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ARDS: Searching for Effective Therapies

Published by: Datamonitor

Published: Jul. 5, 2002 - 19 Pages


Table of Contents


EXECUTIVE SUMMARY

INTRODUCTION TO ARDS

Disease Definition

Causes of ARDS

Epidemiology

TREATMENT APPROACHES

Mechanical ventilation

Unmet needs in ARDS therapy

OUTLOOK FOR DRUG THERAPY

Surfactants

Product pipeline

Analysis of potential new therapies

Market considerations

Intellectual Property Disputes

Safety Concerns

REASON FOR CAUTIOUS OPTIMISM

© Datamonitor 2002. All Rights Reserved.

Abstract

Introduction: Surfactants, long the primary treatment for infant respiratory distress syndrome (IRDS), are now being investigated for application to Acute Respiratory Distress Syndrome (ARDS). To date, however, clinical trials have produced mixed results. Scope of this Report: * Analysis based on review of the most recent published reports of clinical trials results evaluating potential ARDS therapies * Summary of treatment practices and unmet clinical need in ARDS. Report Highlights: Five surfactants are already marketed for the related condition, IRDS. Surfactants remain the most promising class of drugs in development for ARDS. While other drug classes, such as glucocorticoids, have also been investigated for use in ARDS therapy, trial results have proved disappointing. Key Reasons to Buy this Report: * To evaluate potential commercial opportunities in a market having no approved drugs * To assess competitors in the respiratory market

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