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The HIV Pipeline - A Complete Overview

Published by: Datamonitor

Published: Jul. 5, 2002 - 65 Pages


Table of Contents


ACTION POINTS

Outline of the brief

Four key things you need to know about the HIV Market

HIV PIPELINE ANALYSIS BY CLASS

NNRTI Product Pipeline

Calanolide A

AG 1549

TMC125

NRTI Product Pipeline

Coactinon

Coviracil

Ziagen / Epivir Combination

Amdoxovir

MIV-310

ACH-126,443

PI Product Pipeline

Zrivada

Amprenavir pro-drug

PNU-140690

TMC114

DMP-450

Entry Inhibitor Product Pipeline

T-20

Viraldon

PRO-542

S1360

T-1249

AMD3100

Immunotherapeutic Product Pipeline

Proleukin

Reticulose

WF10

HE2000

Biologics Product Pipeline

Remune

AIDSVAX B/E & M/E

MVA-BN HIV NEF

L.E.A.P.S. with HGP-30

VIR201

Other Products in Pipeline

Ampligen

Memantine

COMPANY ANALYSIS

HIV Pipeline Class Composition

Diversity of Pipeline

Analyst Insight

APPENDIX

R&D research methodology

Hypothesis formulation

Hypothesis testing

Data verification and quality control

References

Bibliography

Relevant links

Datamonitor's Infectious Disease Business Unit

Contacts and Future Readings

Abstract

Introduction: Analysis of the late and early stage HIV pipeline, including antiretrovirals, vaccines and immunotherapies, and identifying licensing opportunities across geographical markets and differentiated therapeutic sectors. Scope of this Report: * Class by class analysis of the 101 pipeline candidates currently in development for the treatment of HIV * Drug classes include NNRTIs, NRTIs, Protease Inhibitors, Entry Inhibitors, Immunotherapeutics and Biologics * Interpretation of clinical and commercial aspects of the 31 candidates in phase II and III trials * Comparative overview of the characteristics of the HIV pipeline by class composition, and company type * Strategic insight into the future shape of the market, and key considerations for players at all levels from discovery to marketing specialists. Report Highlights: HIV management is due to undergo a major shift with the imminent introduction of new classes of therapeutic products. While the majority of pipeline candidates appear to be intended for complementary use with conventional therapeutics, some may have the potential to force older products out of the market. Differentiation, forced by a plateau in advance in meeting unmet need, will attract new players from distinct sectors to compete in the HIV market, forcing conventional market leaders to reappraise both their position in the market, and approach to its future domination. Whilst some new market entrants may be able to drive their own market penetration, the majority will require the market presence of more established players to achieve market entry. Tactical collaboration will prove central to market growth. Key reasons to Buy this Report: * Features, benefits, strengths and weaknesses of all major products set to enter the HIV market and a reference to all developmental compounds * Assess the impact of novel class entry on current HIV therapeutics, and the flexibility of existing classes to counter this potential revolution * Appraise the strategies employed by market leaders to counter the imminent arrival of numerous new market entrants * Identify the tactics new market entrants will employ to maximize impact on a market currently dominated by a small number of strong competitors * Identify potential candidates for licensing through an independent analysis of the positioning of pipeline candidates and their developers.

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