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Strategic Perspectives: Oncology licensing strategies - how will targeted therapies affect the licensing market?

Published by: Datamonitor

Published: May. 15, 2002 - 139 Pages


Table of Contents






EXECUTIVE SUMMARY

Scope

Datamonitor insight into licensing in oncology

INTRODUCTION

Drivers and barriers to pharmaceutical in-licensing

Drivers of licensing agreements

Barriers to forming licensing agreements

Filling pipeline gaps with suitable products

Portfolio fit

Other product features

Finding the right partner

Sales and marketing strength

Disease area expertise

Experience in launching products

Technical expertise

Geographic presence

Global reputation

Sales of currently launched products

Further funding options and future relationships

Cultural fit

IN-LICENSING BY COMPANIES WITH ONCOLOGY EXPERTISE

Introduction

Case study: BMS and ImClone

Bristol-Myers Squibb and the cytotoxics market

Erbitux to the rescue

ImClone: partnering for success?

So what went wrong?

Peace, time and good data: the only route to a resolution

Making the most of a bad situation: the long-term forecast

Will a delayed launch allow competitors to steal Erbitux’s thunder?

Conclusions

IN-LICENSING AN ONCOLOGY PORTFOLIO

Introduction

Case Study: Roche and Genentech

The deal that gained Roche an empire

What did Roche get when it bought Genentech?

US focus for Genentech

Roche’s cancer portfolio in 2001

Conclusions

LICENSING TO GAIN ACCESS TO NEW GEOGRAPHICAL MARKETS

Introduction

Case study: Pierre Fabre, GlaxoSmithKline and Navelbine

Navelbine (vinorelbine)

Licensing to GlaxoSmithKline

Pierre Fabre’s future cytotoxic compounds

GSK’s growth strategy: an attractive licensing partner?

Conclusions

LICENSING TO GAIN ACCESS TO THE JAPANESE MARKET

Introduction

Maximizing market share: effective promotion of cancer agents for out-licensers

Building the ideal cancer portfolio…

Case Study: Aventis, Chugai and Taxotere

Aventis and Taxotere

The Japanese cytotoxics market

Chugai and Taxotere

Conclusions

Domestic firms can be useful when gaining marketing approval

Japanese market now more penetrable

Retaining flexibility

LICENSING IN THE BIOTECH INDUSTRY

Introduction

Licensing deals within the biotechnology industry

Case Study: Amgen, Johnson & Johnson and epoetin alfa.

Amgen

Epoetin alfa

The out-licensing of epoetin alpha to J&J

Legal issues between J&J and Amgen

Amgen and J&J go head-to-head in arthritis indication

Has J&J helped Amgen achive its potential?

Has J&J damaged its reputation as a licensing partner?

Conclusion

The good, the bad and the ugly

APPENDIX

Datamonitor's Oncology Business Unit

Primary Research methodology

Primary research

Opinion Leader Interviews

Pipeline productivity index methodology

Sales Data Research Methodology

Introduction

Hypothesis formulation

Hypothesis testing

Data verification with key contacts

Quality control

R&D Research Methodology

Introduction

Hypothesis formulation

Hypothesis testing

Data verification and quality control

Supplementary data

Brain Cancer

Breast Cancer

Colorectal Cancer

Head & Neck Cancer

Leukemia

Lung Cancer

Melanoma

Ovarian Cancer

Pancreatic Cancer

Prostate Cancer

Bibliography

Future readings

Relevant links

How to contact experts in your industry

© Datamonitor 2002. All Rights Reserved.



Abstract

Strategic Perspectives: Oncology Licensing Strategies reviews and analyses the licensing issues most relevant to the current oncology market. In today’s dynamic oncology arena, the number of classical cytotoxics — the traditional foundation of cancer pharmaceuticals organizations — in development is decreasing, while the number of immunotherapies, vaccines and small molecule drugs is increasing at an exponential rate. Few pharmaceutical companies can afford to invest heavily in the development of multiple technology platforms or in more than a few of the widely diverse products in pipeline or on the market. How can acceleration in new areas be achieved? While some pharmaceutical companies have chosen the direct route of developing technology platforms and/or purchasing companies with expertise in their areas of interest, there is an increasing, across-the-board trend toward in-licensing to provide the strength and depth of product portfolio that will help maintain a share of a rapidly expanding oncology therapeutics market. This report covers the general features of licensing decisions and the means by which effective and lucrative licensing deals can be made for both in-licenser and out-licenser. The report is based upon the most likely scenarios faced by those companies involved in-licensing issues, defined by company type. The first section covers the general issues that surround licensing, and further chapters cover licensing by pharmaceutical companies of different sizes and levels of expertise in oncology, using case studies as an informational tool. The final chapter brings together the lessons that can be learned from the case studies within each chapter and formulates a number action points that oncology R & D managers and marketing can use to develop effective licensing agreements within oncology.

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