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Treatment-resistant depression: An untapped area of the patient population

Published by: Datamonitor

Published: Mar. 18, 2002 - 37 Pages


Table of Contents






TABLE OF CONTENTS

INTRODUCTION

Overview of treatment-resistant depression

EPIDEMIOLOGY

Risk factors for TRD

Prevalence of major depression

Prevalence of TRD

TREATMENT STRATEGIES

Overview

Switching strategies

Effexor

Wellbutrin

Remeron

Augmentation/combination strategies

Augmentation strategy

Combination strategy

Non-pharmacological strategies

Electroconvulsive therapy

Vagus nerve stimulation

THE FUTURE DECODED

Developing augmentation therapy

New entrants into the market

Conclusion

APPENDIX

Contributing experts

Bibliography

References

Websites

DATAMONITOR HEALTHCARE

© Datamonitor 2002. All Rights Reserved.



Abstract

Increasingly, treatment-resistant depression (TRD) is becoming a focus for not just antidepressant manufacturers that operate in this market, but also healthcare providers, the media, national governments and patient groups. This is because TRD is being ever more recognized as a major problem within the overall treatment of major depression. In the literature surrounding this segment of the depression patient population, TRD is also known as refractory depression or intractable depression. Consequently, this market brief discusses the prevalence rate of TRD, illustrates the strategies employed by manufacturers of major antidepressant brands to gain access to this patient group, examines other strategies employed by psychiatrists, for example, augmentation or combination therapy, to treat this patient set and outlines Datamonitor’s recommendations for manufacturers of existing brands and those aiming to enter the market in how to maximize the revenues they accrue from this section of the patient population.

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