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Conference Documentation: Advances in Anti-Arthritic Agents

Published by: SMI Publishing, Ltd

Published: Apr. 24, 2002


Table of Contents


9.10 <<...>> RESEARCH TRENDS IN DISEASE-MODIFYING AGENTS FOR ARTHRITIS

Directions for the next generation of arthritis agents

Dr Philip Simon, Executive Director, Arthritis & Bone Metabolism, Novartis

9.40 <<...>> MATRIX METALLOPROTEASE INHIBITORS

Potential arthritis disease modification drugs?

Dr Yetunde Taiwo, Associate Director, Arthritis & Bone Research, Procter &
Gamble

10.20 <<...>> DEVELOPMENT OF P38 MAP KINASE AND ICE/CASPASE-1 INHIBITORS

New classes of orally active, anti-cytokine anti-inflammatory drugs

John Randle, Program Executive, Vertex

11.20 <<...>> NOVEL KINASE TARGETS AND INHIBITORS FOR THE TREATMENT OF
INFLAMMATORY DISEASES

Next generation of oral antirheumatic drugs

Dr Alan Lewis, President, Signal Research Division, Celgene

12.00 <<...>> NOVEL NON-INFLAMMATORY COMPOUND

Novel inhibitor of TNFa

Dr Somesh Sharma,, Chief Scientific Officer, Calyx Therapeutics

1.40 <<...>> CP1-1714: A NON-IMMUNOSUPPRESSIVE INHIBITOR OF PROINFLAMMATORY
GENE EXPRESSION

Potential DMARD properties in preclinical models of rheumatoid arthritis

Dr Paul Wood, President & Chief Executive Officer, Centaur Pharmaceuticals

2.20 <<...>> SelCIDS/ImiDs: POTENTIAL ANTI-ARTHRITIC AGENTS

New compounds for an old malady

Dr David Stirling, Chief Scientific Officer & Executive Vice President,
Pharm Research & Development, Celgene Corporation

3.00 <<...>> THE ROLE OF CYTOKINE TRAPS IN THE TREATMENT OF RHEUMATOID
ARTHRITIS (RA

Dr Scott Mellis, Vice President, New Product Planning, Regeneron

4.00 <<...>> UNDERSTANDING RHEUMATOID ARTHRITIS PATHOPHYSIOLOGY

A novel in silico human model for evaluating anti-arthritic targets,
pathways and therapies in the joint

Thomas Paterson, Chief Scientific Officer, Entelos

4.40 <<...>> MANAGING THE IMAGING COMPONENT
Demonstration of structural benefit in phase 3 RA studies

Klaus Noever, Director, Business Development & Clinical Affairs, Bio-Imaging
Technologies


9.00 <<...>> Chairman's Opening Remarks

Dr K Wayne Marshall, President and Chiefe Executive Officer, ChondroGene

9.10 <<...>> VAP-1: A NOVEL DRUG DEVELOPMENT TARGET

Vascular Adhesion Protein-1 as a drug target in rheumatoid arthritis

Dr Timo Veromaa, Vice President, Drug Development, BioTie Therapies

9.40 <<...>> ANTIBODIES TO INTERFERON-g IN THE THERAPY OF RHEUMATIC
DISEASES

IFN-g: a key cytokine in the pathogenesis of autoimmune diseases, including
rheumatoid arthritis

Dr Simon Skurkovich, Vice President, Research & Development, Advanced
Biotherapy

10.20 <<...>> ANTI-INFLAMMATORY ENGINEERING WITH PROTEINS

Progression of a membrane-targeted complement regulator in RA

Dr Richard Smith, Chief Scientific Officer, AdproTech

11.20 <<...>> AN ALTERNATIVE APPROACH TO DRUG THERAPY FOR ARTHRITIS

Enhancement of existing medicines

Dr Alan Rothaul, Senior Pharmacologist, Arakis

12.00 <<...>> NO-RELEASING DRUGS AS POTENT ANTI-ARTHRITIC AGENTS

Dr Jean Luc Burgaud, External Research Collaborations Manager, NicOx

1.40 <<...>> FAST DISSOLVE: A GREAT NEW DOSAGE FORM FOR PAIN THERAPY

Fast dissolve for pain therapy

Dr John Siebert, President & Chief Executive Officer, CIMA LAB

2.20 <<...>> MESENCHYMAL STEM CELL THERAPY: APPLICATIONS IN JOINT DISEASE

Mesenchymal stem cell-based therapy offers great promise for tissue
regeneration. In vivo studies show that in several types of connective
tissue defects there is enhanced and more rapid repair when these cells are
delivered to the site of injury

Dr Frank Barry, Director, Arthritis Research, Osiris Therapeutics

3.00 <<...>> THE ROLE OF GENOMICS IN TACKLING ARTHRITIS

Genetic approaches to identifying new drug targets

Dr Jerry Lanchbury, Reader, Molecular Immunogenetics, King's College

4.00 <<...>> CHONDROCYTE GENOMICS

Implications for development of disease-modifying OA therapies

Dr K Wayne Marshall, President & Chief Executive Officer, ChondroGene

4.40 <<...>> BOTANICAL DRUGS AND OSTEOARTHRITIS

A re-evolution from salicylates to willow bark

Dr Reinhard März, Head, Medical Science & Research, Bionorica

5.20 <<...>> Chairman's Closing Remarks and Close of Conference






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