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Published by: BioInformatics, LLC
Published: Jun. 1, 2002 - 119 Pages Special discount! Hard copy regularly $3200, now just $800!
Table of Contents
Section 1. Executive Overview & Introduction
- Among the Study’s Key Findings
Section 2. Study Methodology & Demographics
- Objectives
- Comments
- Definition of Terms
- Market Segment
- Organization Size
- Laboratory Size
- Region
- Job Position
- Area(s) of Research Expertise
- Questionnaire Used to Conduct the Study
Section 3. Significant Findings
- Product Use & Application
- Product Expectations
- Technology & Suppliers
Section 4. Presentation of Survey Data
Product Use & Application
- Current use of NMR
- Location of NMR experiments
- Principle reason why NMR experiments are not performed within own lab/group
- Applications for which NMR is used
- Type(s) of spectrometers used
- Method(s) typically used to optimize NMR experimental results
- Type(s) of spectra acquired in NMR experiments
- Type(s) of NMR experiments typically conducted
- Maximum radio frequency of the NMR spectrometer most typically used
- Type(s) of protection against stray magnetic fields employed on the NMR spectrometer most commonly used
- Techniques used in combination with NMR used
- Emerging NMR technologies currently used
- Number of samples run per month
- Average number of different NMR experiments performed on a single sample
- Future use of NMR
- Application(s) for which NMR software is primarily used
- Kinds of NMR software packages most commonly used
Product Expectations
- Most influential features in decision to use one NMR spectrometer over another
- Most influential factor in decision to purchase one NMR spectrometer over another
- Most significant performance limitation lab experiences when performing NMR
- Most valuable improvement to conventional NMR technology
- Most important characteristic in selecting one NMR software package over another
- Most influential factor in decision to purchase one NMR spectrometer software over another
- Interest in utilizing automated NMR sample preparation
- Area the NMR industry should focus its product development efforts
Technologies & Suppliers
- “Top-of-mind” company/supplier for NMR spectrometers
- Primary supplier for NMR spectrometers and related products and services
- Familiarity with suppliers of NMR spectrometers and related products and services
- Primary supplier of commercial NMR software packages
- Familiarity with suppliers of commercial NMR software packages
- Estimated percentage of current total annual budget for products/services dedicated to NMR applications
- Estimated percentage of future total annual budget for products/services dedicated to NMR applications
- Additional comments as to where suppliers should focus their efforts to better meet needs in the area of NMR products and services
Section 5. Cross Tabulations of Survey Data
- Questions and answer choices tabulated against Market Segment, Region, Area of Research(s) or other relevant questions.
Section 6. Appendix
- Other Published Reports
- About BioInformatics
- Our Valued Clients
AbstractRather than providing a broad overlook of the drug discovery market, BioInformatics’ series, The Tools & Techniques of Drug Discovery, looks in-depth at six different market segments though the eyes of a worldwide panel of research scientists. Based on a 33-question survey, Nuclear Magnetic Resonance (NMR) is the sixth of six titles in the series and focuses specifically on NMR technology to help suppliers better serve and satisfy this market.
Structural data is critical in determining how a potential drug will bind with a target molecule. Nuclear magnetic resonance screening of multiple targets and the rational design of high-affinity ligands are now a main focus of drug discovery efforts. The objective of this report is to provide understanding of how researchers are applying various NMR spectroscopy disciplines within drug discovery - including library screening, rational design of high-affinity ligands and structure-activity relationships.
Given the diversity of its applications, NMR spectroscopy has become, and will continue to remain, indispensable to the pharmaceutical and biotech industries. Adaptations of current NMR methods along with improvements to instrumentation are currently being developed as scientists implement high-throughput, automated approaches to accelerate the drug discovery process. Such approaches are necessary in order to fully characterize the large number of proteins currently being generated by structural genomics research.
These types of developments in NMR technology are forging a path for exciting new applications in both solution- and solid-state research. Nuclear Magnetic Resonance will explore end-users’ satisfaction with industry innovations such as the integration of sophisticated radio frequency, improved digital electronics, automated probe/sample handling technologies and advanced bioinformatics. It will also assess researcher’s needs for increased sensitivity and greater throughput capacity, which is essential for companies wishing to increase the efficiency of the drug discovery process.
Objectives
The major objectives of this report are as follows:
- Examine the use and application of NMR in drug discovery research.
- Determine what features are most influential in purchasing decisions.
- Identify the preferred suppliers of NMR spectrometers and related products and services (including software packages).
- Establish the parameters for quality in NMR products and services.
- Understand—from the user’s perspective—the level of satisfaction with current products and any unmet needs in the area of NMR spectroscopy.
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