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Published by: BCC Research
Published: Feb. 1, 2002 - 332 Pages
Table of Contents
Title
Introduction/Summary
Assays
Market For Microarray Biochip Business To Cross $1 Billion By 2005
Ligand-Controlled Biochip Hybrids
Snp Scoring Wins Patent
Cytochrome Activity Sensors Patented
Peptide Libraries Expressed In Cells
Large-Scale Snp Assay Validated
Basic Science
Market For Angiogenesis Regulating Products To Reach $2.4 Billion In 2006
Antidepressants Make Nerves Grow
No Stored In Blood Cells
Oncogenic Protein Kills Leukemia
Latency Of Hiv Explained
Cannabinoids In The Brain
Expanding The Genetic Code
Killer Cells Target Viruses
Gateways To Death Identified
Cocaine Changes Brain’s Circuits
Hiv-Infected Rat May Be Human Model
Gbv-C Virus Interferes With Aids
Tumors Lay Down Tracks
Nanowire Nanosensors Analyze Molecules
Pheromones Change Brain Activity
Enzyme Involved In Memory Retention
How Anthrax Toxin Kills Us
Movement Of Single Molecules Imaged
Hiv Protein Cracks Open Cell Nucleus
Smallpox Research Program Initiated
Colors Reveal Protein Structure
Alzheimer’s Proteins In Transport
Collaborations
Rheumatoid Diagnostic Deal Signed
Rolling Circles Amplify Dna
Antifungal Joins Antibacteral Agent
Petacrunchers On The Way
Pancreatic Insufficiency Alliance Formed
Repligen Hopes To Cure Autism
Trans-Pacific Functional Genomics Collaboration
Cogent, Elan Tackle Polyglutamine Diseases
Swiss Deal On Genomics
Central Nervous System Collaboration
Coming-3.5 Million Points Of Data
Zinc Finger To Target Hiv
Antibiotic Discovery Agreement Signed
Optical Biochip Licensing Deal
Genotyping Analysis Alliance Begun
Bristol Meyers And Exelixis Team Up
Rigel, Novartis In Angiogenesis Pact
Translating Technology Into Danish
Anti-Fusion Anti-Virals
Agreement On Secreted Proteins
Novartis Embraces Inverse Genomics
Combinatorial Chemistry
Virtual Lab Wins Patent
Bar Codes For Chemicals
On Bead Screening And Identification
Diagnostics
Market For New Therapeutics And Diagnostics For Stds On The Rise
U.S. Market For Treating Women’s Disorders To Cross $30 Billion By 2005
Stroke Test Earns Patent
Glucose Predicts Heart Disease
Pcr Test For Hiv Accepted For Review
Clinical Trial Of Fertility Monitor
Epithelial Cells Correlate With Cancer
Micrometastases Found In "Negative" Patients
Breast Cancer Serum Assay
Neural Networks Analyze Gene Data
Cf Test Could Be Improved
Screening For Single Gene Defects
Labmap Assay Approved By Fda
Cantilever Measures Antigen Concentration
Proteins Used As Chemical Sensors
Fusion Gene Diagnostic Of Childhood Cancer
Grant For Biowarfare Agent Detection
Rolling Amplification Detects Papilloma
Melanoma P16 Test Launched
Tiger Stalks Bioterror Agents
Rapid Id Of Salmonella Strains Possible
Drug Delivery
Advanced Drug Delivery Systems To Cross $27 Billion By 2005
Fishnet Polymers For Proteins Patented
Oral Compounds Modulate Gnrh
Camptothecins Linked To Polyglutamate
Electroporation Increases Bleomycin Toxicity
Parathyroid Hormone Delivered Orally
Peptide Delivery Through The Skin
Transdermal Patch For Adhd Treatment
Intranasal Morphine Under Development
Oral Delivery Of Insulin Successful
Way To The Brain Is Through The Nose
Polymeric Micelles For Drug Transport
Subsidiary Formed To Exploit Polymer
Unit Formed To Deliver Proteins
Anti-Angiogenesis Nanoparticles
Oral Delivery Of Macromolecules
Fighting Nasty Toenail Fungus
Taking Interferon Through The Nose
First Week Predicts Success Of Hiv Drugs
Blood Test For Creutzfeld-Jacob
Bioterror Detection Device Developed
Drug Targets
Method Traps Malaria Parasites
Breast, Ovarian Cancer Targets Identified
Lexicon, Abgenix Seek Drug Targets
Dopamine Receptor Tied To Obesity
Src As A Stroke Target
Slowing A Runaway Immune Response
Hep C Virus Clamps Onto Ribosomes
Making Room For Fat
Targeting Tumor’s Blood Supply
Baylor Creates Leaner Mice
Enzyme Involved In Cocaine Addiction
Glutamine Causes Rat Addicts To Relapse
Muscle Protein Linked To Dystonia
Slamming Door On Potassium
Ion Channel Defect Produces Paralysis
Are Ligases Important Drug Targets?
Gene Responsible For High Cholesterol
Type 1 Diabetes Reversed In Mice
Glycation End Products Factor In Alzheimer’s
Pdgfr-Alpha In Hedgehog Pathway
Receptors For Trace Amines Discovered
How Staph A Resists Methicillin
Cell Cycle Protein Patented
Triglyceride Levels Regulator Identified
Ion Channel Protein Contraceptive Target
Macrophage Inhibitor Factor Licensed
Collagenase Plays Role In Atherosclerosis
Links Between Parkinson’s Forms
Enzyme Controls Immune Responses
Wasting Of Mice And Men
Human Genome
Take A Look At Yourself
Industry News
Blood Industry To Cross $8.6 Billion By 2006
Advanced Wound Care Business To Cross $3 Billion By 2005
Rx-To-Otc Market To Continue Expansion
Worldwide Market For Cardiovascular Drugs To Cross $76 Billion By 2005
Innovative Therapies To Boost The Cancer Treatment Market In The Next Four Years
A Lion Swallows Trega Biosciences
Centocor Licenses Thrombin Inhibitors
Merger Forms Entigen Corp.
Epigenomics Merges With Orca
Cheap Aids Drugs Offered
Ivax Buys Mexican Drug Marketer
High-Tech Industry Lured
Biotech Business Plan Competition
Kidney Disease Effort Established
Cellmark Goes To Orchid
Cancer Drugs On The Way
Diabetes Funding To Be Boosted
J & J Acquires Alza Corp.
Vertex To Acquire Aurora Biosciences
Merck To Buy Rosetta Inpharmatics
Spending On Drugs Rising Fast
Gemini Genomics, Sequenom To Merge
Many Ms Patients Are Not Treated
Venture Capital Down, Except For Biotech
Biotech 2001: More Is Better
Baxter Buys Oncology Subsidiary
Deltagen Acquires Arcaris
Statin Drugs Defended
Bayer Fights Sea Of Troubles
Half Of Pharmaceutical Licensing Deals Fail
Transmission Of Drug- Resistant Hiv Rare
Drugs For Elderly Swell Pipeline
"Glue Grants" For Two Consortiums
Endocrine Trials Network Established
One Patent Down, One Upheld
Is Pharmageddon On The Horizon?
Life Science Vc Fund Formed
Biotech Industry Merge Continues
There’s Action In Mergers, Acquisitions
Gift Will Establish Neuroscience Institute
Informatics
Gene Ontology Under Development
Acne-Generating Organism Sequenced
Chemically Perceptive Database Software
Spotfire Linked To Celera’s Databases
Analysis Of Non- Synonymous Snps
Virulent Streptococcus Pyogenes Sequenced
Mouse Genome Completed
Computational Hologram Patent Awarded
Meta-Analysis Makes Most Of Clinical Data
Distributed Computing Speeds Genomics
Screens Identify Small Rnas
Gene Function Database Introduced
Celera To Aid In Snp Linkage Map
Harnessing Unused Processing Cycles
Supercomputers For Biological Modeling
Electrostatic Models For Microtubules
Expresso Analysis Of Microarray Data
Sun Shines On Life Sciences
New Compounds
Worldwide Market For Prophylactic And Therapeutic Vaccines To Approach $10 Billion By 2006
Worldwide Market For Bulk Pharmaceutical Actives To Cross $77 Billion By 2005
Chocolate May Protect The Heart
Statins For Alzheimer’s?
Phase Ii Trials For Ergo-1
Compound Inhibits Angiogenesis
Fatty Acid Linked To Antipsychotic
Creating New Kinase Inhibitors
Hiv Entry Inhibitor To Be Developed
Agonist For Retinal Detachment
Histone Deacetylase Inhibitor For Leukemia
Sealing Damaged Neural Membranes
Phospholipase Inhibitortreats Atherosclerosis
Drug Candidates From Sea Sponges
Nitro-Aspirin Reduces Restenosis
Tnf Inhibitor For Rheumatoid Arthritis
Clinical Results Of Natrecor Reviewed
An Apple A Day?
Neurotrophin Causes Weight Loss
Alkaloid Shrinks Prostate Tumors
Reducing Cross-Linkers Prevent Kidney Disease
Dna Binding Compounds Kill Yeasts And Molds
Substance P Antagonist Closes The Door On Hiv
Preclinical Testing Of Anti-Thrombin Iii
Histatin Tested Against Candidiasis
Compound Makes Fat Mice Thin
Vitamin C Precursor Treats Stroke
Antagonist Calms Irritable Bowels
Natrecor Is Finally Cleared
Inhibitor For Rheumatoid Arthritis
Cpg Oligo Triggers Type 1 Interferons
Two Ilex Drugs Enter Clinic
Hypoxic Cell Cytotoxin Fights Cancer Cells
Nda Filed For Cold Treatment
Gaucher Disease Therapy Tested
Blocking Mucus To Treat Cystic Fibrosis
Patent For Protein Inhibitors Issued
Patents Picket Proteasome Inhibition
Ubiquitin Ligase Agreement Signed
Inverse Agonist Tested As Anti-Psychosis Agent
Cancer Drug From Marine Bacteria
Patent Awarded On Hiv Fusion Inhibitor
Kinase Inhibitor Blocks Tumor Growth
Antibiotics From Biofilm Blocking
Triggering Cell Death In Leukemia
Genomics Yields Anti-Obesity Drug
A Suppressor Of Ige Synthesis Discovered
Old Compounds
Steroids Don’t Slow Copd
Selegiline Doesn’t Increase Death Risk
Antibiotics To Treat Asthma?
Aspirin Targets Dendritic Cells
Cyclophosphamide Cures Aplastic Anemia
Melatonin Inhibits Alzheimer’s Aggregates
Thalidomide Inhibits Cyclooxygenase-2
Outlook 2001
Looking Back, And Looking Ahead
Informatics
Pharmacogenomics
New Compounds
Screening
Microfluidics
Finance
Peptides
Synthetic Hdl Mimic Tested
Cholesterol Binding Peptide Licensed
Single Amino Acid Alters Crf Binding
Peptide Critical To Cirrhosis Development
Remedy For Burkholdia Cepacia
Specific Peptides, Natural Antibiotics
Insulin Mimics Identified
Pharmacogenomics
Linking Multiple Genes To Diseases
Assay Ids High Hiv Drug Susceptibility
Dna Chips Predict Drug Response
Secure Pharmacogenomic Information Storage
Racial Bias In Hepatitis Drug Reactions Studied
Tnf Polymorphism Affects Pneumonia
Proteomics
Biotechnology — Revolutionizing Healthcare
Market For Bone And Joint Therapies To Double In The Coming 5 Years
Yummy Enhances Cell Research
Microfluidics For Protein Analysis
Mapping A Protein Family
Seeking Markers For Depression
Commercializing Protein Chips
Protein/Protein Interaction Info
Chromotography Meets Mass Spec
High-Throughput Platform Agreements
Rosetta Scores On Folding Test
The Whole Human Proteome Project
Protein Profiling Patent Issued
Proteomics Factory Opens In Geneva
When Proteins Stress Out
Protein Microarrays Use Affibodies
Nmr For Protein Ligand Interactions
Improving On Nature’s Folding
Kinesin Wobbles; Keeps On Truckin’
Nano-Sized Barcodes For Immunoassays
Entire Yeast Proteome Analyzed
3-D Map For Meningitis
Ww Domain Signaling Pathway Studied
Publications
Buying Enzymes Off The Shelf
Biotech 2001, More Is Better
Rational Drug Design
De Novo Drug Design Agreement
Cystic Fibrosis Protein Solved
Preventing Hiv Attachment
Industrialization Of Nmr Techniques
Designable Protein Structures Generated
Crystal Structure Of Ribosomes Obtained
How Statins Lower Cholesterol
Pathogen Protein Structure Deciphered
Structure Of Glycogen Synthase Kinase Solved
A Better Inhibitor For Alzheimer’s Disease
Big Computer For Drug Design
Nanotech Dendrimers As Drug Candidates
Structure Of Protease Drug Target Solved
Structure Of Brca Terminus Revealed
Topoisomerase I Target Of Anti-Cancer Agents
Synchroton Beamlines For Structure Studies
Nmr Used To Design Inhibitors
Robotics
Introducing The ‘Gene Gin’
Manipulating Cells With Magnetic Fields
Microfluidics-Based Dna Synthesis
Screening
Invader Looking At Hemochromatosis
Fluorescent Protein Is Tracking Device
Hts Screening Yields New Drug Candidates
Ubiquitin Is Disease Indicator
Mous Announces Rat Apps From Lion
Darpa Grant For Bio-Flips
Snp Map Of Mouse Genome Planned
Dna Fragment Labchip Available
Screening Of P450 Cytochrome Inhibitors
Nanopore Discriminates Between Dna Molecules
Exo-Proofreading Aids Snp Recognition
High Throughput Genotyping
Bioelectronic System Detects Mutations
Microfluidic Screening Agreement Signed
Zebrafish Get Gene Screen
Initiative Uses Third Wave Assays
High-Throughput Cell Analytic Tool
High Throughput Topological Analysis
Special Report
American Diabetes Assn. 61st Annual Sessions
Technology Conference
Too Much Money, Too Few Drugs
Impact Of Genomics On Pharma R&D
List Of Tables
Summary Table:
Worldwide Revenues For Selected Drug Discovery Related Products, Through 2005
1 Worldwide Market For Microarrays, Arrayers, Scanners And Microfluidics, Through 2005
2 Market For Angiogenesis Regulating Products, Through 2006
3 U.S. Market For New Therapeutics And Diagnostics Std Products By Disease Category, Through 2005
4 Market Size For Treatment And Diagnosis Of U.S. Women’s Disorders, Through 2005
5 Advanced Drug Delivery Systems, Through 2005
6 U.S. Blood Industry, Through 2006
7 Value Of Advanced Wound Care Business, Through 2005
8 The U.S. Market For Rx-To-Otc Switched Ingredients, Through 2005
9 Worldwide Sales Of Cardiovascular Drugs By Disease Category, Through 2005
10 Worldwide Market For Cancer Therapy Products, Through 2005
11 Worldwide Market For Prophylactic And Therapeutic Vaccines, Through 2006
12 Worldwide Market For Pharmaceutical Active Ingredients, Through 2005
13 Market For Selected Biotechnology Enabling Technologies And Star Products, Through 2005
14 Market For Bone And Joint Therapies By Type, Through 2005
List Of Figures
Summary Figure:
Worldwide Revenues For Selected Drug Discovery Related Products, 2001 And 2005
1 Worldwide Market For Microarrays, Arrayers, Scanners, And Microfluidics, 2001 And 2005
2 Market For Angiogenesis Regulating Products, 2001 And 2006
3 U.S. Market For New Therapeutics And Diagnostics Std Products By Disease Category, 2001 And 2005
4 Market Size For Treatment And Diagnosis Of U.S. Women’s Disorders, 2001 And 2005
5 Advanced Drug Delivery Systems, 2001 And 2005
6 U.S. Blood Industry, 2001 And 2006
7 Value Of Advanced Wound Care Business, 2001 And 2005
8 The U.S. Market For Rx-To-Otc Switched Ingredients, 2001 And2005
9 Worldwide Sales Of Cardiovascular Drugs By Disease Category, 2001 And 2005
10 Worldwide Market For Cancer Therapy Products, 2001 And 2005
11 Worldwide Market For Prophylactic And Therapeutic Vaccines, 2001 And 2006
12 Worldwide Market For Pharmaceutical Active Ingredients, 2001 And 2005
13 Market For Selected Biotechnology Enabling Technologies And Star Products, 2001 And 2005
14 Market For Bone And Joint Therapies By Type, 2001 And2005
AbstractDrug development and manufacturing are rapidly changing. Its no longer just the influence of biotechnology. Now, new screening techniques such as combinational chemistry are having a profound impact. This unique compilation covers developments and news in drug discovery, new compounds, synthesis, bulk manufacturing, compounding, formulation, excipients, drug delivery, new regulations, and industry news.
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