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Published by: BCC Research
Published: Jan. 1, 2002 - 135 Pages
Table of Contents Title
Introduction
Study Goals And Objectives
Reasons For Doing The Study
Audience For The Report
Scope And Format
Methodology And Information Sources
Bcc Information And Related Bcc Studies
Disclaimer
Executive Summary
Overview: Proteomics And The Current Proteomics Market Structure
What Is Proteomics?
Tools Of Proteomics
2-D Electrophoresis
Mass Spectroscopy
Bioinformatics
Other Important Proteomics Tools
Protein Chips
Capillary Hplc
Uses Of Proteomics Technologies
In Academia
Uses In Drug Discovery
Uses In Diagnostics
Industry Perceptions Of Proteomics And Its Potential
An Important Note
Government Regulations
Introduction
Drug Discovery
Preclinical Testing And Submission Of An Ind
Submission Of An Nda
Post-Fda Approval
Conclusions
Other Financial Issues Related To Pharmaceuticals
New Drug Approvals
Mass Spectroscopy
Basic Theory
Liquid Chromatography And Mass Spectroscopy Combined
Mass Spectroscopy Markets: 2000 To 2006
Time-Of-Flight Mass Spectroscopy
Maldi-Tof
Q-Tof
Lc-Ms: Quadrupole Mass Spectroscopy
Lc-Ion Trap Mass Spectroscopy
Other Developments In The Mass Spectroscopy Business
Proteomics Markets
Two-Dimensional Electrophoresis
Other Techniques For Separating Protein Mixtures
Market Outlook
Suppliers
Market Leaders In 2-D Electrophoresis
Capillary Electrophoresis (Ce)
Background
Other Ce Techniques For Analyzing Proteins
Protein Chips
Recent Advances And Future Outlook
Bioinformatics
Structure Of The Bioinformatics Industry
Bioinformatics And Proteomics: Databases
Bioinformatics And Proteomics: Software For Analysis
Concluding Remarks
Patent Trends
Mass Spectroscopy
Patents By Year Of Issuance And By Type
Patent Assignees
Capillary Electrophoresis Patent Trends
Patents By Year Of Issuance And By Type
Patent Assignees
Two-Dimensional Electrophoresis Patent Trends
Patents By Year Of Issuance And By Type
Patent Assignees
Company Profiles
Mass Spectroscopy Instrument Suppliers
Agilent Technologies, Inc.
Applera Corporation
Applied Biosystems
Bear Instruments, Inc.
Gbc Scientific Equipment, Pty. Ltd.
Hitachi Instruments, Inc.
Kratos Analytical
Micromass
Perkinelmer, Inc.
Phenomenex
Richard Scientific, Inc.
Shimadzu Scientific Instruments
Spark Holland
Thermo Electron
Thermo Separation Products (Thermoquest)
Varian, Inc.
Waters Corporation
2-D Electrophoresis Or Capillary Electrophoresis Suppliers
Amersham Pharmacia Biotech
Bio-Rad Laboratories
Compugen
Decodon, Gmbh
Dionex Corporation
Gene Logic
Geneva Proteomics
Genomic Solutions, Inc.
Invitrogen
Large Scale Biology Corporation
Micro-Tech Scientific
Nonlinear Dynamics
Proteome Systems Ltd.
Scimagix
Zaxis, Inc.
Protein Chip Companies
Applera Corporation
Biosite, Inc.
Celera Genomics
Ciphergen Biosystems, Inc.
Genomic Solutions, Inc.
Glaucus Proteomics
Hts Biosytems
Hybrigenics Sa
Illumina, Inc.
Large Scale Biology Corporation
Lumicyte, Inc.
Phylos, Inc.
Protiveris
Somalogic, Inc.
Zyomyx, Inc.
Bioinformatics Companies
Axcell Biosciences Corporation
Celera Genomics Group
Geneva Bioinformatics
Geneprot (Geneva Proteomics)
Genomic Solutions, Inc.
Hybrigenics Sa
Incyte Genomics
Inpharmatica Ltd
Integrative Proteomics
Mds Proteomics
Myriad Genetics, Inc.
Proteome Systems Ltd.
Structural Bioinformatics
List Of Tables
Summary Table: Revenues For Selected Proteomics-Related Products,* Worldwide Forecast, Through 2006
1 Publications Conerning Proteomics
2 A Sample Of 2-D Electrophoresis Suppliers
3 A Sample Of Mass Spectroscopy Suppliers
4 A Sample Of Companies Involved In Proteomics-Bioinformatics
5 A Sample Of Protein Chip Companies
6 Important Capillary Hplc Companies
7 R&D Spending In The Pharmaceutical Industry, 1980 To 2001
8 Distribution Of Drug Research Costs
9 Drugs Approved By The Fda, 1993 To 2000
10 Mass Spectroscopy Expenditures, Through 2006
11 Market-Specific Mass Spectroscopy Expenditures, Through 2006
12 Overall Market Shares For Mass Spectroscopy, 2000
13 Selected Maldi-Tof Models
14 Q-Tof Models
15 Selected Quadrupole Mass Spectrometers
16 Selected Ion Trap Mass Spectrometer Models
17 2-D Gel Electrophoresis Expenditures, Through 2006
18 Selected Units For 2-D Electrophoresis Units*
19 Selected Software Packages For Analyzing 2-D Electrophoresis Experiments
20 The Capillary Hplc Market, Through 2006
21 Selected Models Of Automated Capillary Hplc Equipment
22 Selected Models Of Automated Capillary Electrophoresis Equipment
23 Projections For Protein Chip Revenues, Through 2006
24 Suppliers Of Protein Chips
25 Projections For Bioinformatics Expenditures, Through 2006
26 Selected Commerical Proteomics Databases
27 Selected Software Packages For Analyzing 2-D Electrophoresis Experiments
28 Mass Spectroscopy Patents By Year Of Issuance: 1996 To July 2001
29 Patents By Technology Type, 1996 To July 2001
30 Patents Relating To Protein Sequencing By Mass Spectroscopy, 1996 To July 2001
31 Patents By Assignee Classification
32 Patents By Institution, 1996 To July 2001*
33 Capillary Electrophoresis/Mass Spectroscopy Patents
34 Maldi-Tof Patents
35 Proteomics-Related Methods/Mass Spectroscopy Patents
36 Capillary Electrophoresis Patents By Year Of Issuance, 1996 To July 2001
37 Capillary Electrophoresis: Apparatus And Reagents Patents, 1996 To July 2001
38 Capillary Electrophoresis: Methods Patents, 1996 To July 2001
39 Capillary Electrophoresis Patents By Technology Type, 1996 To July 2001
40 Capillary Electrophoresis Patents By Assignee Classification
41 All Electrophoresis Patents By Institution, 1996 To July 2001*
42 Two Dimensional Electrophoresis Patents By Year Of Issuance, 1986 To July 2001
43 Two Dimensional Electrophoresis: Apparatus And Reagents Patents, 1986 To July 2001
44 Two Dimensional Electrophoresis: Methods Patents, 1989 To July 2001
45 Patents By Technology Type, 1996 To July 2001
46 All Electrophoresis Patents By Institution, 1996 To July 2001*
List Of Figures
Summary Figure: Revenues For Selected Proteomics-Related Products,* Worldwide Forecast, 2000, 2001 And 2006
1 Drugs Approved By The Fda, 1993 To 2000
2 Mass Spectroscopy Expenditures, 2000, 2001 And 2006
3 Overall Market Shares For Mass Spectroscopy, 2000
4 Protein Separation Using 2-D Electrophoresis
AbstractProteomics is an emerging field that has developed in the wake of genomics. Its goal is to understand protein expression at the cellular level, and apply this information to scientific and medical problems. For example, compared to healthy cells, how does influenza virus infection affect the total protein output? Are any of the proteins expressed only in the infected cells suitable targets for new antiviral drugs? This approach also applies to cancerous cells, and cells from patients with degenerative diseases and many other conditions. New technologies like protein chips and capillary electrophoresis are emerging to serve proteomic studies, and more mature technologies like 2-D electrophoresis, mass spectroscopy, and nuclear magnetic resonance spectroscopy are being adapted for protein studies, and in some cases, for high throughput uses. Bioinformatics applications are constantly being developed to analyze the data produced by all of these technologies. This BCC study examines how proteomics technologies have affected basic research and pharmaceutical research, and how they are likely to affect research in the near future. It also analyzes how proteomics technologies are developing, and examines new companies that are likely to make substantial contributions to the field. An important part of the report analyzes instruments that are vital to proteomics studies. Sales and spending projections through 2006 are included.
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