Proteomics 2002: Commercial & Technological Potentials

Published by: PJB Publications USA Inc.

Published: Feb. 1, 2002 - 200 Pages

Table of Contents

1.1 Defining Proteomics

1.2 Report Description

1.3 Executive Summary

1.3.1 Protein Separations

1.3.2 Protein Analysis by Mass Spectrometry

1.3.3 Protein Biochips

1.3.4 Bioinformatics

1.3.5 Proteomics Services and Information

1.3.6 Opportunties, Obstacles, and Future Trends

2. Overview of Proteomics

2.1 Proteomics Today: 2001

2.1.1 Proteomics and Genomics

2.1.2 Today’s Suppliers, Products, and Services

2.1.3 Today’s Proteomics Markets

2.2 Proteomics in the Mid Term: 2002-2005

2.2.1 Protein Separation and Purification

2.2.2 Protein Identification

2.2.3 Functional Characterization

2.2.4 Structural Analysis

2.2.5 Bioinformatics

2.3 The Future of Proteomics: 2006 and Beyond

2.3.1 Diagnostics

2.3.2 Pharmaceuticals

3. Market Analysis for Protein Separation and Analysis Tools

3.1 Protein Separation by 2DGE

3.1.1 Market Leaders

3.1.2 Product Examples

3.1.3 Market Size and Growth

3.2 Protein Separation by HPLC and Capillary LC

3.2.1 Market Leaders

3.2.2 Product Examples

3.2.3 Market Size and Growth

3.3 Protein Separation by ICAT

3.3.1 Market Leader

3.3.2 Market Size and Growth

3.4 Separation to Analysis by Gel-to-Mass Products

3.4.1 Market Leaders

3.4.2 Product Examples

3.4.3 Market Size and Growth

3.5 Protein Analysis by MALDI-MS and LC/MS

3.5.1 Market Leaders

3.5.2 Product Examples

3.5.3 Market Size and Growth

3.6 Protein Analysis by Tandem MS Systems (MS/MS)

3.6.1 Market Leaders

3.6.2 Product Examples

3.6.3 Market Size and Growth

3.7 The Bioinformatics Connection

4. Market Analysis for Advanced Proteomics Tools

4.1 Structural Analysis Tools

4.1.1 X-ray Crystallography

4.1.2 Nuclear Magnetic Resonance

4.1.3 In silico Modeling

4.2 Functional Characterization Tools

4.2.1 Phage Display

4.2.2 Two-Hybrid Systems

4.3 Protein Biochips

4.3.1 Applications for Protein Biochips

4.3.2 Market Leaders

4.3.3 Market Size and Growth

4.4 Bioinformatics Tools

4.4.1 Applications for Bioinformatics in Proteomics

4.4.2 Market Leaders

4.4.3 Market Size and Growth

5. Market Analysis for Proteomics Information and Services

5.1 Late Stage Proteomics Companies

5.1.1 Oxford GlycoSciences

5.1.2 Large Scale Biology Corp.

5.1.3 Hybrigenics SA

5.1.4 CuraGen

5.2 Mid Stage Proteomics Companies

5.2.1 MDS Proteomics

5.2.2 Inpharmatica

5.2.3 Syrrx

5.3 Early Stage Proteomics Companies

5.3.1 GeneFormatics

5.3.2 GeneProt (formerly Geneva Proteomics)

5.3.3 Glaucus Proteomics

5.4 Market Size and Growth

6. Market Expectations and Opportunities

6.1 Market Bottlenecks and Opportunities

6.1.1 Enhanced Automation

6.1.2 Information Integration

6.1.3 Market Development

6.2 Interviews With Proteomics Industry Experts

6.2.1 Hybrigenics: Donny Strosberg, CEO

6.2.2 Oxford GlycoSciences: Michael Kranda, CEO

6.2.3 Leading Pharmaceutical Company: R&D Executive

6.3 Future Trends

6.3.1 Trends for Tool Providers

6.3.2 Trends for Proteomics Companies

6.3.3 Trends for Proteomics in Big Pharma

7. Company Profiles

7.1 ACLARA BioSciences

7.2 Agilent Technologies

7.3 Amersham Biosciences

7.4 Applied Biosystems

7.5 Applied Precision

7.6 Astex Technology Ltd.

7.7 AxCell Biosciences

7.8 Biacore International AB

7.9 BioCarta

7.10 Bio-Rad Laboratories

7.11 BioVisioN AG

7.12 Bruker Daltonics

7.13 Caliper Technologies

7.14 Ciphergen Biosystems

7.15 Compugen

7.16 CRS Robotics

7.17 CuraGen Corporation

7.18 GeneFormatics Inc.

7.19 GeneProt

7.20 Genetix, Ltd.

7.21 Genomic Solutions

7.22 Glaucus Proteomics B.V.

7.23 Hybrigen

7.24 Hybrigenics SA

7.25 Illumina, Inc.

7.26 IMGENEX

7.27 Incyte Genomics, Inc.

7.28 Inpharmatica

7.29 Large Scale Biology Corp.

7.30 Matritech

7.31 MDS Proteomics

7.32 Micromass

7.33 NextGen Sciences Ltd.

7.34 Oxford GlycoSciences Plc

7.35 Nonlinear Dynamics Ltd.

7.36 Packard Bioscience

7.37 Pharmacopeia, Inc.

7.38 Promega

7.39 Proteome Systems Ltd.

7.40 Sequenom

7.41 Structural Bioinformatics, Inc.

7.42 Structural Genomix

7.43 Syrrx

7.44 Thermo Finnigan

7.45 Zyomyx

8. Company Directory: Other Companies Involved in Proteomics

Appendix: Glossary of Terms and Abbreviations

Abstract

But: what is the real commercial potential of these tools? And how are they being used?

Proteomics 2002 dissects the proteomics sector, to answer the crucial questions about this burgeoning field:

• How are proteomics tools being used in drug discovery today? By whom? With what results?
• What new protein analysis tools are being developed? In which areas? By whom?
• Who are the leaders in proteomics services? Who are their partners?

Proteomics 2002 explores the technological state-of-play and commercial drug discovery potential of the most important proteomic approaches, including:

• Protein separation and purification, including 2-D gel electrophoresis and liquid chromatography, ICAT, and gel-to-mass analysis
• Protein identification, including mass spectrometry and matrix-assisted laser desorption/ionization time of flight
• Protein functional characterization, including yeast two-hybrid, phage display, and protein biochips Structural analysis, including X-ray crystallography modeling, nuclear magnetic resonance spectroscopy, and in silico modeling
• Bioinformatics, including database management and modeling.

Proteomics is shaping the future of drug discovery and advanced diagnostics.

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