MicroRNAs and Exosomes Market Report 2012

Published by: Select Biosciences Limited

Published: Aug. 1, 2012 - 168 Pages

Table of Contents

Chapter I. MicroRNA Research Market Analysis

Scope

Segmentation of the RNA Space

MicroRNA genes, non-coding RNA genes

Primary Market Survey to Assess microRNA Research Trends

Qualitative and Quantitative Market Data

MicroRNA Grant Funding Metrics in the US

miRBase Registry Metrics

MicroRNA Research Market Size and Growth Rate

Heat Map of microRNA Research and its Evolution

Detailed Analysis of microRNA-Focused Publications as a Means to Segment the Space

Expansion of the microRNA Field

MicroRNA Association Documented in Various Disease Classes: Potential for Development into Biomarkers

Translational Value of microRNA Associations

The Potential for Long Non-coding RNAs

Long Non-coding RNAs Market Trends

Chapter II. MicroRNAs in Physiological and Disease Processes

Cancer

microRNAs Documented in Chromosomal Alterations/Aberrations

Epigenetic Silencing of microRNAs

microRNA Expression Profiles in Hematological Malignancies

microRNA Expression Profiles in Solid Tumors

microRNAs Associated with Outcome in Cancers [Cancer Personalized Medicine]

microRNAs in Breast Cancer

microRNAs in Lung Cancer

microRNAs in Prostate Cancer

microRNAs in Pancreatic Cancer

microRNAs in GI Tract Cancers

Normal Muscle Development and Vascular Disease

microRNAs Associated with Vascular Disease, Inflammation and Angiogenesis

microRNAs Associated with Cardiac Hypertrophy

Diabetes

CNS Normal Development and Diseases

Stem Cells

Hepatic Physiology, Pathology, and Toxicity Screening

Chapter III. Exosomes Market Analysis

Exosomes Characteristics

Exosomes Market Trends

Quantitative Analysis of Research Market Trends

Worldwide Market Survey Data and Trends Therein

Emerging Space of Circulating Biomarkers

Sources of Circulating Nucleic Acids

Plasma microRNAs as Candidate Biomarkers in Various Disease Classes

Signatures of Circulating Cell-Free microRNAs in Various Cancer Classes

Comparison of Various Classes of Biomarkers

Appendix. Research Methodology

Abstract

This is the latest and most up-to-date Market Report from Select Biosciences addressing the microRNA and Exosomes markets as they are evolving. In this report, we focus upon the microRNA research marketplace from the perspective of the translational opportunities in these spaces. The focus of this field is moving from basic research towards the utility of associations of microRNA expression patterns in disease. In this manner, microRNA signatures may be validated as biomarkers in many disease areas—cancers, cardiovascular disease, neurological disease, inflammation, and metabolic diseases.

Select Biosciences has performed worldwide market tracking wherein we’ve analyzed end-user research trends in the microRNA as well as Exosome markets—these areas are evolving in parallel given the opportunity in the Circulating Biomarkers space and the utility of microRNAs and mRNAs to be harvested from exosomes and assayed as signatures for disease.

For exosomes, we’ve analyzed the research trends, types of downstream applications being performed as well as biomarker classes being studied currently and this is the First Market Report to Document the Market Landscape of Exosomes.

Select Biosciences has characterized the associations of microRNAs in various disease classes and presents these detailed associations as “hotspot maps” in this report. Specifically, these associations [to be interpreted as starting material for biomarker development and validation] are described for many cancer classes, cardiovascular disease, CNS disease, diabetes, inflammation, and obesity. They offer the opportunity for R&D planning efforts addressing the question of “which microRNA content needs to be addressed in a particular disease class.”

This data-driven characterization of the microRNAs and Exosomes landscape is a hands-on document that can be used for competitive benchmarking, business planning, and strategy development—all the data that have been collected in this industry analysis are presented and they form the basis for the conclusions drawn throughout the market report presented in a format enabling “drag-and-drop” into business presentations/business plans—this Market Report is written and delivered to customers in PowerPoint format.

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