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Published by: AdvanceTech Monitor
Published: Sep. 1, 2001 - 266 Pages
Table of Contents 1. Executive Summary
2. Introduction
3. Knowledge Management to
Enable the Emerging R&D Model
- Forces driving change
- The future R&D organization
- Components of a knowledge management solution
- Accenture's proprietary model
4. Measuring Return on Knowledge
- The concept of knowledge management
- Aligning knowledge communities
- Implementing knowledge management
- Post-implementation lessons and considerations
5. Design and Implementation of Knowledge Management Systems
- Organizing knowledge groups
- Enabling knowledge communities
- Components of knowledge management systems
- Research applications
6. Outcomes-Based Knowledge Management (KM)
- Evolution of the KM concept
- Creating a business context
- Components of a clinical trial KM solution
7. Knowledge Creation to Enhance Competitiveness of R&D
- Knowledge that results in a competitive advantage
- Strategies, tools and technologies
- Case studies of knowledge creation
8. Leveraging Technology to Create Knowledge Across the Enterprise
- Current practice of knowledge management in big pharma
- IT strategies and tools used by big pharma
- Case studies of successful knowledge management initiatives
9. IT Systems to Integrate Preclinical Evaluations into Discovery
- Sources and relationship of data
- Tools and technologies for information management
- Managing compounds during drug discovery
10. eBusiness Technologies and Pharmaceutical R&D
- Current IT systems to manage pharmaceutical R&D
- Software solutions for integrating legacy systems Features of a successful knowledge management solution
11. Integrated IT Systems for Global Research
- Challenges facing research IT organizations
- Key strategies and practices of IT groups in pharmaceutical R&D
- The use of IT to coordinate global research
- Lessons learned from other industries
12. Modeling as a Tool for Knowledge
Creation and Sharing
- The role of modeling in tactical and strategic decisions
- Framework for modeling the R&D process
- The use of modeling to understand the behavior of R&D
13. From Disseminating Data to Knowledge Management
- Lilly's experience in knowledge management initiatives
- Creating tools and techniques to generate knowledge
- Using knowledge management rating tools to assess progress
14. Better Decision-Making Through Data-Mining and Visualization
- Systems for data storage, mining and analysis
- Building predictive models for improved R&D
- Data-mining and visualization in drug discovery and clinical trials
15. Communities of Practice to Create and Share Knowledge
- Rationale for creating communities of practice
- Selecting and implementing practice communities in R&D
- Lessons learned
16. Implementation of a Global Expertise Locator
- The concept of expertise locators
- Implications of company-specific approaches
- Lessons learned from pilot studies
17. The Role of KM in Library Design
- Incorporating historical knowledge into drug library design
- Computational modeling of drug candidates
- Virtual screening of virtual libraries
18. Informative Library Design in Drug Discovery
- Rationale for improving library design
- Computational techniques to improve active site modeling
- Modeling library design for library enrichment
19. Increasing Efficiency of Lead Identification and Optimization
- Current practices in lead identification and optimization (LI/LO)
- Integrating the elements of LI/LO for knowledge creation
- Techniques for improving efficiency ofLI/LO
20. Improving Decision-Making During Drug Discovery
- Factors driving change in drug discovery
- Layering techniques for managing knowledge systems
- Meta approaches to utilize data and information
- Data-mining tools to create knowledge
21. Knowledge Management Solutions for Data-Rich Applications
- Managing combinatorial libraries
- Computing physical property distributions
- Data compression methods for performance optimization
- Managing high-throughput screening data
AbstractThis report examines the impact of knowledge on competitiveness, outcomes-based knowledge management, the role of technology in data capture and dissemination of information, knowledge management solutions in drug discovery and more. Perspectives and Approaches from:
- Consulting firms
- Technology providers
- Big Pharma
- AstraZeneca Pharmaceuticals
- Aventis Pharmaceuticals, Inc.
- Eli Lilly & Company
- GlaxoSmithKline
AdvanceTech Monitor (ATM) reports give you a unique
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expert analysis of the technology and business strategies
behind The Pharmaceutical Industry's Need for
Knowledge Management, more than 100 tables and
figures to illustrate points of discussion and more than
150 Web links to key Internet sources of information.
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