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Published by: Renub Research
Published: Jun. 8, 2011 - 95 Pages
Table of Contents- 1. Executive Summary
- 2. Worldwide Prevalence of Alzheimer’s Patients
- 2.1 Total Number of Alzheimer’s Patients
- 2.2 Total Number of Early Stage Alzheimer’s Patients
- 2.3 Total Number of Late Stage Alzheimer’s Patients
- 3. Regional Estimates for Alzheimer’s Patients
- 3.1 Africa
- 3.1.1 Total Number of Alzheimer’s Patients
- 3.1.2 Total Number of Early Stage Alzheimer’s Patients
- 3.1.3 Total Number of Late Stage Alzheimer’s Patients
- 3.2 Asia
- 3.2.1 Total Number of Alzheimer’s Patients
- 3.2.2 Total Number of Early Stage Alzheimer’s Patients
- 3.2.3 Total Number of Late Stage Alzheimer’s Patients
- 3.3 Europe
- 3.3.1 Total Number of Alzheimer’s Patients
- 3.3.2 Total Number of Early Stage Alzheimer’s Patients
- 3.3.3 Total Number Of Late Stage Alzheimer’s Patients
- 3.4 Latin America & Caribbean
- 3.4.1 Total Number of Alzheimer’s Patients
- 3.4.2 Total Number of Early Stage Alzheimer’s Patients
- 3.4.3 Total Number of Late Stage Alzheimer’s Patients
- 3.5 North America
- 3.5.1 Total Number of Alzheimer’s Patients
- 3.5.2 Total Number of Early Stage Alzheimer’s Patients
- 3.5.3 Total Number of Late Stage Alzheimer’s Patients
- 3.6 Oceania
- 3.6.1 Total Number of Alzheimer’s Patients
- 3.6.2 Total Number of Early Stage Alzheimer’s Patients
- 3.6.3 Total Number of Late Stage Alzheimer’s Patients
- 4. Worldwide Alzheimer’s Disease Market
- 4.1 North America Alzheimer’s Disease Market
- 4.2 Europe Alzheimer’s Disease Market
- 4.3 Rest of the World Alzheimer’s Disease Market
- 5. Worldwide - Alzheimer’s Drug Market Share 2008 - 2009
- 6. Worldwide - Top 10 Alzheimer’s Drug Brands Market Performance
- 6.1 Exelon (Rivastigmine) - Past, Present & Future Forecast
- 6.2 Aricept (Donepezil) - Past & Present Market
- 6.3 Razadyne (Galantamine) (Past & Present Market)
- 6.4 Memantine (Namenda, Ebixa, Axura)
- 6.4.1 Namenda (Memantine) - Past, Present & Future Forecast
- 6.4.2 Ebixa (Memantine) - Past, Present & Future Forecast
- 6.4.3 Axura (Memantine) - Past, Present & Future Forecast
- 6.5 Nootropil (Piracetam) - Past, Present & Future Market
- 6.6 Prometax (Rivastigmine) - Past, Present & Future Forecast
- 6.7 Memac (Donepezil)
- 6.8 Eranz (Donepezil)
- 6.9 Future Blockbuster Alzheimer’s Drug
- 7. Alzheimer’s Disease Deals, 2005 - 2009
- 8. Key Drivers of Growth in Global Alzheimer’s Disease Drug Market
- 8.1 Aging Population
- 8.2 Unmet Medical Needs
- 8.3 Future Drugs for Disease Modification in Alzheimer’s Disease
- 9. Key Challenges in the Global Alzheimer’s Disease Drug Market
- 9.1 Lack of Validated Targets & Lack of Animal Models
- 9.2 Barriers in the Design and Implementation of Clinical Trials
- 9.3 Barriers in Academia & Regulatory Issues
- 10. Key Players in the Alzheimer’s Drug Market
- 10.1 Forest Laboratorie
- 10.2 Eisai
- 10.3 H. Lundbeck A/S
- 10.4 Novartis
- 10.5 Merz GmbH & Co. KGaA
- 10.6 Johnson & Johnson
- 10.7 UCB
- List of Figures:
- Figure 2 1: Worldwide - Number of Patients with Alzheimer’s Disease (Million), 2006 - 2010
- Figure 2 2: Worldwide - Number of Patients with Early Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 2 3: Worldwide - Number of Patients with Late Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 1: Africa - Number of Patients with Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 2: Africa - Number of Patients with Early Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 3: Africa - Number of Patients with Late Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 4: Asia - Number of Patients with Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 5: Asia - Number of Patients with Late Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 6: Europe - Number of Patients with Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 7: Europe - Number of Patients with Early Stage Alzheimer ’s Disease (Million), 2006 - 2010
- Figure 3 8: Europe - Number of Patients with Late Stage Alzheimer ’s Disease (Million), 2006 - 2010
- Figure 3 9: Latin America & Caribbean - Number of Patients with Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 10: Latin America & Caribbean - Number of Patients with Early Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 11: Latin America & Caribbean - Number of Patients with Late Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 12: North America - Number of Patients with Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 13: North America - Number of Patients with Early Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 14: North America - Number of Patients with Late Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 15: Oceania - Number of Patients with Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 16: Oceania - Number of Patients with Early Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 3 17: Oceania - Number of Patients with Late Stage Alzheimer’s Disease (Million), 2006 - 2010
- Figure 4 1: Worldwide - Alzheimer’s Disease Market (Billion US$), 2006 - 2010
- Figure 4 2: Worldwide - Future Forecast for Alzheimer’s Disease Market (Billion US$), 2011 - 2015
- Figure 4 3: North America - Alzheimer’s Disease Market (Billion US$), 2006 - 2010
- Figure 4 4: North America - Future Forecast for Alzheimer’s Disease Market (Billion US$), 2011 - 2015
- Figure 4 5: Europe - Alzheimer’s Disease Market (Billion US$), 2006 - 2010
- Figure 4 6: Europe - Future Forecast for Alzheimer’s Disease Market (Billion US$), 2011 - 2015
- Figure 4 7: Rest of the World - Alzheimer’s Disease Market (Billion US$), 2006 - 2010
- Figure 4 8: Rest of the World - Forecast for Alzheimer’s Disease Market (Billion US$), 2011 - 2015
- Figure 5 1: Worldwide - Drug Companies Market Share in Alzheimer’s Disease Market (Percent), 2008
- Figure 5 2: Worldwide - Drug Companies Market Share in Alzheimer’s Disease Market (Percent), 2009
- Figure 6 1: Worldwide - Exelon Alzheimer’s Drug Sales (Million US$), 2005 - 2010
- Figure 6 2: Worldwide - Future Forecast for Exelon Alzheimer’s Drug Sales (Million US$), 2010 - 2014
- Figure 6 3: Worldwide - Aricept Alzheimer’s Drug Sales (Billion US$), 2005 - 2009
- Figure 6 4: Worldwide - Razadyne Alzheimer’s Drug Sales (Million US$), 2007 - 2009
- Figure 6 5: Worldwide - Namenda Alzheimer’s Drug Sales (Million US$), 2003 - 2010
- Figure 6 6: Worldwide - Future Forecast for Namenda Alzheimer’s Drug Sales (Million US$), 2011 - 2015
- Figure 6 7: Worldwide - Ebixa Alzheimer’s Drug Sales (Million US$), 2003 - 2010
- Figure 6 8: Worldwide - Future Forecast for Ebixa Alzheimer’s Drug Sales (Million US$), 2011 - 2014
- Figure 6 9: Worldwide - Axura Alzheimer’s Drug Sales (Million US$), 2003 - 2010
- Figure 6 10: Worldwide - Future Forecast for Axura Alzheimer’s Drug Sales (Million US$), 2011 - 2014
- Figure 6 11: Worldwide - Nootropil Alzheimer’s Drug Sales (Million US$), 2004 - 2010
- Figure 6 12: Worldwide - Future Forecast for Nootropil Alzheimer’s Drug Sales (Million US$), 2011 - 2014
- Figure 6 13: Worldwide - Prometax Alzheimer’s Drug Sales (Million US$), 2007 - 2010
- Figure 6 14: Worldwide - Future Forecast for Prometax Alzheimer’s Drug Sales (Million US$), 2011 - 2012
- Figure 6 15: Worldwide - Memac Alzheimer’s Drug Sales (Million US$), 2007 - 2009
- Figure 6 16: Worldwide - Eranz Alzheimer’s Drug Sales (Million US$), 2007 - 2009
- Figure 8 1: Worldwide - Population Aged 60 or Over: World and Development Regions, 1950, 1975, 2009, 2025 & 2050
- Figure 8 2: Worldwide - Old-Age Dependency Ratio: Major Areas, 2009 & 2050
- List of Tables:
- Table 2 1: Worldwide - Forecast For Number of Patients with Alzheimer’s (Million) 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 2 2: Worldwide - Stages of Alzheimer’s Disease
- Table 2 3: Worldwide - Forecast for Number of Patients with Early Stage Alzheimer’s Disease (Million) 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 2 4: Worldwide - Forecast for Number of Patients with Late Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 1: Africa - Forecast for Number of Patients with Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 2: Africa - Forecast for Number of Patients with Early Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 3: Africa - Forecast for Number of Patients with Late Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 4: Asia - Forecast for Number of Patients with Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 5: Asia - Number of Patients with early stage Alzheimer’s Disease (Million), 2006 - 2010
- Table 3 6: Asia - Forecast for Number of Patients with Early Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 7: Asia - Forecast for Number of Patients with Late Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 8: Europe - Forecast for Number of Patients with Alzheimer ’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 9: Europe - Forecast for Number of Patients with Early Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 10: Europe - Forecast for number of patients with late stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 11: Latin America & Caribbean - Forecast for Number Of Patients with Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 12: Latin America & Caribbean - Forecast for Number of Patients with Early Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 13: Latin America & Caribbean - Forecast for Number of Patients with Late Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 14: North America - Forecast for Number of Patients with Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 15: North America - Forecast for Number of Patients with Early Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 16: North America - Forecast for Number of Patients with Late Stage Alzheimer’s Disease (Million), 2011 - 2016, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 17: Oceania - Forecast for Number Of Patients with Alzheimer’s Disease (Million), 2011 - 2016, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 18: Oceania - Forecast for Number of Patients with Early Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 3 19: Oceania - Forecast for Number of Patients with Late Stage Alzheimer’s Disease (Million), 2011 - 2015, 2020, 2025, 2030, 2035, 2040, 2045, 2050
- Table 6 1: Worldwide - Bapineuzumab Drug Future Forecast Sales, (Billion US$), 2016
- Table 7 1: Worldwide - Alzheimer’s Disease Deals, 2005 - 2009
- Table 8 1: Worldwide - Population Aged 60 or Over, 65 or Over and 80 Or Over By Sex (Thousands): World, Major Areas and Regions, 2009
- Table 10 1: Forest Laboratories - Key Financials (Million US$), March 2008 - March 2010
- Table 10 2: Eisai - Key Financials (Million US$) March 2008 - March 2010
- Table 10 3: H. Lundbeck A/S - Key Financials (Million US$), 2007 - 2009
- Table 10 4: Novartis - Key Financials (Million US$), 2007 - 2009
- Table 10 5: Merz GmbH & Co. KGaA - Key Financials (Euro Million) 2007/08 - 2008/09
- Table 10 6: Johnson & Johnson - Key Financials (Million US$) 2007 - 2009
AbstractAlzheimer’s Disease - Market Overview
Alzheimer’s is a complex disease and there is no single “magic bullet” available in the market to prevent or cure it. Though many marketed drugs have been approved for Alzheimer’s disease, but it still remains a significant area of unmet medical need. Clinical success has proven elusive; however, numerous companies are developing novel treatments. Currently there’s no cure for Alzheimer’s and its still waiting for its key product. In addition, all current marketed products are going to be generic in the next five years.
In 2010, there were more than 30 Million people suffering with Alzheimer’s disease but it is anticipated that by 2015 over 35 Million people worldwide will be suffering from this disease. Much of this increase will be due to increase in number of people with Alzheimer’s in low and middle income countries. Since the risk of getting the disease increases with age, the number of patients with the illness to be found in any community will depend on the proportion of older people in the group. Traditionally, the developed countries have large proportions of elderly people, and so they have many cases of Alzheimer’s disease in the community at one time. However, developing countries are also undergoing a demographic transition so that more and more persons are surviving to an old age.
Global Alzheimer’s disease has increased manifold and expected to cross US$ 19 Billion by 2015. North America controls more than 50% of the total Alzheimer’s drug market share in 2010. Over the past years, the Alzheimer’s disease market has been flagged with several drugs into the market. Till last year Aricept was the world best selling drug which lost patent protection in November 2010, a milestone that will be followed by a rapid loss in sales. But there are other drugs which has the potential to become blockbuster drug by 2010. Namenda, Exelon has shown alluring growth in the market and become blockbusters in 2010. Ebixa a drug of Memantine group is expected to have a Billion dollar market by 2014. Given the alarming worldwide growth in Alzheimer’s patients, and especially if companies are able to address major unmet needs, the outlook for the Alzheimer’s disease market is excellent.
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