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The World Market for Addiction Disorders, 2009 - 2016

Published by: Spectra Intelligence

Published: Oct. 1, 2009 - 81 Pages


Table of Contents


Chapter 1. Introduction to Addiction Disorders

Addiction: Substance Characteristics and Prevalence of Misuse

Neurobiological Basis of Addiction

Prevalence of Substance Misuse - Estimates for North America, Europe and Asia

North America

United States

Canada

Europe

Asia (Japan)

Incidence Estimates for Addiction Disorders in North America, Europe, and Japan

Treatment Options

Chapter 2. The Addiction Pharmacotherapy Market

Market Overview for Addiction Disorders

Market Forecasts by Therapeutic Area

Alcohol Addiction

Narcotic Addiction

Tobacco Addiction


Chapter 3. Alcohol Addiction Market

Alcohol Addiction

Acamprosate (Campral) - Merck Serono/Forest Laboratories

Disulfiram (Antabuse) - Alpharma

Naltrexone Hydrochloride

Alkermes - Reformulated Naltrexone (Vivitrol)

Pipeline Focus for Alcohol Addiction - Biotie Therapies Corp

Nalmefene

Naltrexone Depot

Alcohol Addiction - Market Insights and Future Considerations

Chapter 4. The Narcotic Addiction Market

Global Narcotics - Usage Statistics

Narcotic Addiction - The Scale of the Problem

Pharmacotherapies for Narcotic Addiction - Market Evaluation

Opioid Addiction Pharmacotherapies

Drug Substitute Therapies

Subutex/Suboxone (Buprenorphine) - Schering-Plough/Reckitt Benckiser

Suboxone Reformulation

Methadone

Drugs to Control Opioid Withdrawal Symptoms

BritLofex (Lofexidine); Opizone (Naltrexone) - Britannia Pharma/STADA

Naltrexone

Nalorex - Bristol-Myers Squibb

Opizone - Britannia

Therapeutic Switching in Addiction Markets

Outlook for Pharmacotherapeutic Markets Related to Alcohol and Narcotic Abuse

Chapter 5. Tobacco Addiction

Prevalence and Mortality Statistics

Nicotine: Mechanism of Action

Tobacco Dependence and Smoking Cessation

Smoking and Health Consequences

Healthcare Costs of Smoking Addiction

Tobacco Addiction Pharmacotherapeutics

Market Analysis of Smoking Cessation Pharmacotherapeutics

Nicotine Replacement Therapies

Nicorette/Nicotrol - McNeil Healthcare/Johnson & Johnson

Sales Estimates

NiQuitin/NicoDerm/Nicorette/Nicabate - GlaxoSmithKline

Sales Estimates

Nicotinell/Habitrol - Novartis

Sales Estimates

Neuromodulating Pharmacotherapies for Smoking Cessation

Zyban (Bupropion) - GlaxoSmithKline

Sales Estimates

Champix/Chantix (Varenicline) - Pfizer

Sales Estimates

Tobacco Addiction - Market Insights and Future Considerations

Chapter 6. Drugs in Research and Development

Addiction Disorders - Research and Development Overview

Pipeline Addiction Pharmacotherapies

Alcohol Dependence

Cocaine Dependence

Novel Late-Stage Candidates

Celtic Pharmaceuticals

Synosia Therapeutics/Roche

Cannabis Dependence

Immunotherapy Focus - InterveXion Therapeutics

Opioid Dependence

Late-Stage Development Products for Opioid Dependence

Impulse Control Disorders

Pipeline Focus - Gambling Addiction

Tobacco/Nicotine Dependence

Pipeline Focus on Immunotherapies for Tobacco Dependence

Nabi Biopharmaceuticals - NicVAX

Celtic Pharmaceuticals - TA-NIC

Smoking Cessation - A Transforming Market

Chapter 7. Market Analysis, Therapy Forecasting, and Prospect Mining

Market Analysis and Therapy Forecasting

Therapy Area Forecasts

Comparative Analysis: Addiction Pharmacotherapies

Prospect Mining

Addiction Disorder Pharmacotherapy Prospects

Therapy Area Forecasts 2016 and 2025

Chapter 8. Summary and Key Data Points on the Addiction Market

Key Data Points

Reference Sources

List of Tables

Table 1.1 Neurotransmitter Systems Associated with Addiction

Table 1.2 Drugs of Abuse and their Associations with Neurotransmitter Systems

Table 1.3 Estimated Prevalence of Substance Misuse in Europe, 2009 (000' users)

Table 1.4 Estimated Incidence for Addiction Disorders in North America, Europe and Japan, 2009 (incidence in 000s)

Table 2.1 Market Synopsis for Addiction Disorders: Current data

Table 2.2 Estimated Global Sales (US$) and Annual Growth (%) of Key Drugs to Treat Addictions, 2008-2016

Table 3.1 Physiological Consequences of the Disulfiram-Alcohol Reaction

Table 5.1 Estimated Sales (US$) and Annual Growth (%) of Smoking Cessation Therapies, 2008-2016

Table 6.1 Drugs in Development/Trials for Alcohol Dependence, 2009

Table 6.2 Drugs in Development/Trials for Cocaine Dependence, 2009

Table 6.3 Drugs in Development/Trials for Cannabis Dependence, 2009

Table 6.4 Drugs in Development/Trials for Ampetamine and Phencyclidine Dependencies, 2009

Table 6.5 Drugs in Development/Trials for Opioid Dependence, 2009

Table 6.6 Drugs in Development/Trials for Impulse Control Disorders, 2009

Table 6.7 Drugs in Development/Trials for Tobacco Addiction, 2009

Table 7.1 Estimated Global Drug Market (US$m) and Growth Rate (%) for Addiction Pharmacotherapies, 2008-2016

Table 7.2 Therapy Area Forecasts for the World Addiction Disorders Market, 2016 and 2025

List of Figures

Figure 1.1 Estimated Prevalence of Substance Misuse in United States, 2009

Figure 1.2 stimated Prevalence of Substance Misuse in Canada, 2009

Figure 1.3 Estimated Prevalence of Substance Misuse in Europe, 2009

Figure 1.4 Estimated Prevalence of Substance Misuse in Japan, 2009

Figure 2.1 Estimated Sales (US$) of Addiction Drugs Segmented by Therapeutic Area, 2008-2016

Figure 2.2 Estimated Global Sales (US$) of Leading Addiction Drugs by Therapy Area, 2009 & 2016

Figure 7.1 Comparative Analysis of Leading Addiction Pharmacotherapies, 2008-2016 (US$m)

Figure 7.2 Key Addiction Disorder Pharmacotherapy Prospects, 2009

Abstract

The substance dependence field is transforming into a high-growth market opportunity. Supported by the success of Pfizer's recently launched Chantix/Champix, which is on track for blockbuster status in the smoking cessation sector, pharmacotherapies in development for alcohol, narcotic, and nicotine dependencies are poised to radically change the addiction treatment landscape in this difficult-to-treat patient population.

The report estimates that the current market for addiction disorders is valued at US$3.2 billion and this is forecast to increase 19% to US$3.8 billion by 2016.

The World Market for Addiction Disorders, 2009 2016: Future Therapies for Substance Dependence and Impulse Control, will introduce the reader a specialty pharmaceutical market which is positioned for high-growth based on analysis of marketed and pipeline drugs, company activities, and addiction disorder demographics.

Therapy area forecasting and illustrative comparative sales data is presented to gain insight into leading products with sales estimates to 2016.

Objectives of Report

The objectives of this 80 page report are to provide an in-depth analysis of the global addiction pharmacotherapeutic market. Included in this study are analyses of key therapy areas, R&D programs, and innovating companies and products. The reader will benefit from market forecasts, pooled knowledge of recent industrial activities and events, and from analytical discourse, which is intended to stimulate growth and create new market opportunities.

Report Highlights Include:
  • The current market for addiction disorders is valued at US$3.2 billion, up from US$2 billion in 2005
  • Critical analysis of alcohol, cocaine, opiate, and nicotine addictions
  • Review of epidemiological, aetiological, and demographic data for addiction disorders
  • Analysis of over 10 key marketed products and inclusion of 34 R&D candidates identified in preclinical to clinical stages of development for addiction disorders
  • Sales estimates (US$) to 2012 for major therapy areas
  • Strategic insights for life-cycle optimization and product development
  • Critical evaluation of leading addiction pharmacotherapies
  • Emerging markets identified and sector analysis
  • Trend analysis of industry events and activities over past 2 years
  • Detailed R&D themes and clusters by addiction area
  • Data generation on sector and market values between 2004 and 2012 and therapy forecasts by 2020 (US$)
  • High revenue-yielding prospects identified with projected sales estimations
  • R&D pipeline positioning for novel candidates
  • Market insights for product development and drug promotion
What you can learn from this report:
  • Which addiction therapies are the current and potential future market leaders
  • How companies are reformulating products for addiction indications
  • Which premarket addiction pharmacotherapies are identified as high-value products
  • Which companies are developing drugs for addiction disorders
  • Sales predictions to 2016 for addiction pharmacotherapies
  • What the likely impact of pipeline products will be on value growth of the addiction market over the 10 years
  • Which addiction subsectors could be niche market opportunities
  • What the future outlook holds for addiction pharmacotherapies
  • Insight into R&D trends for alcohol, cocaine, opiate, and nicotine addictions
  • Which molecules and compounds are main R&D clusters for dependency disorders
  • Which of the pipeline candidates are top prospects in the addiction market over the next decade and to 2025
Report Contains:
  • Detailed survey and analysis of the current and future global addiction disorder market
  • Comprehensive update on key marketed products indicated for alcohol, narcotic, and nicotine dependency disorders
  • Review of epidemiological, demographic, aetiological, and therapeutic data associated with addiction disorders
  • Market analysis and insight of key addiction pharmacotherapies and pipelines
  • Market value predictions of individual marketed products to 2016
  • Insight and trend analysis of pipeline products for addiction disorders
  • Review of promising pipeline products and potential market opportunities
  • Extensive coverage of the R&D pipeline for addiction disorders
  • Guide to leads for potential licensing opportunities


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