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Genetic Engineering

Published by: Global Industry Analysts

Published: Oct. 1, 2009 - 63 Pages


Table of Contents


1.INDUSTRY OVERVIEW

Genetic Engineering: A Prelude

The Evolution and Progress of GM Crops

GM Crops Gain Global Acceptance

GM Cultivation Gains Prominence in Developing Nations

Rising Prices, Food Shortage Make Biotech Grains Attractive

Challenges to GM Crops Adoption

Biotech Regulatory Measures Hinder Crop Domestication

Governments Not to Give Up on GM Hope

US - The Largest Producer of GM Crops

Major Market Participants

2.MARKET DYNAMICS

Global Food Demand to Drive Need for GM Crops

Genetic Engineering - A Solution for Food Crisis!

Harmful or Healthy: Breaking The Myth About GM Crops

Non-food Sectors to Benefit from GE Technology

Genetic Engineering and Enzymes

GE to Help Starch and Sugar Processing Enzyme Market
GE to Drive Demand for Bakery Enzymes

3.ISSUES AND CONCERNS

The GM Food Issue Continues

Nations at Crossroads to Accept or Object GE Crops

Nations Set Global Agenda to Settle GM Crop Controversies

4.REGIONAL TRENDS

US Soybean and Corn Crop to Witness Robust Growth

GMO Crops’ Future Hinges on Co-Existence Measures in EU

UK Government’s GM Crops Proposal Faces Rebuff

Spanish Transgenic Corn Plantation Increases

Chinese Biopharmaceutical Market to Continue its Growth Spurt

Government to Support Biopharmaceutical Innovation
India - The Leading Cultivator of Bt Cotton
India Ousts China in Bt Cotton Cultivation
GM Crops to Earn Good Returns for Australia
Biotechnology - A Boon for Agriculture in Malaysia

Biotech Crops Cultivation Zooms in South Africa

5.GENETIC ENGINEERING: AN OVERVIEW

The Concept…

Molecular Basics - The Gene

Genome - The Information Pool

Evolution of Genetic Engineering

Historical Developments in Genetic
Engineering:

The Human Genome Project
Significant Events in the Past
Gene Therapy
Types of Gene Therapy
Monogenic Gene Therapy

Suicide Gene Therapy

Antisense Gene Therapy

Human Genetic Engineering
Genetic Engineering in Animals

Role of Biotechnology in Agriculture

Insect Resistant Crops Vs. Herbicide Tolerant Crops
Genetically Modified Foods
GM Food Faces Worldwide Criticism During Initial Years
Benefits of Genetically Modified Foods
Pest Resistance
Cold Tolerance

Herbicide Tolerance

Drought and Salinity Tolerance

Disease Resistance

Phytoremediation

Nutrition

Pharmaceuticals

Negative Impacts of GM Foods
Possibility of Crosspollination
Decreased Pesticides Effectiveness

Unintentional Destruction of Other Species

Health Concerns Related to GM Foods

Cost Concerns Related to GM Foods

Genetic Engineering and Food Processing
Genetic Engineering and Regulatory Environment

Patents - An Overview

6.GENE THERAPY - A REVIEW

Factors Influencing Gene Therapy’s Future Development

Human Genome Analysis
Gene Therapy - The Next Generation Cardiovascular Therapy

Public Support for Gene Therapy

RNAi Bode Bright Prospects

Factors Hampering Gene Therapy Future
Development
Stringent US and European Regulatory Laws Prolongs Gene Therapy Development

Identifying Genetic Fault

Immune Response

Delivering Genetic Materials into Patient Cells

Multigene Disorders

Side Effects

Push Towards Germline Gene Transfer

Technical Limitations

Commercialization: A Road Uphill
Time Line in Gene Therapy Drug Development
Table 1: Gene Therapy Clinical Trials (2007): Percentage Breakdown by Geographic Region for the US, Europe, Canada, Japan and Rest of World

Table 2: Gene Therapy Clinical Trials Worldwide (2007): A Split by Development Phase

Various Gene Therapy Products Under Development (2007)

Target Diseases and Players Involved
Key Players by Application Area
Table 3: Gene Therapy Clinical Trials Worldwide (2007): Percentage Breakdown by Disease/ Application Area for Cancer, Heart Disease, Monogenic Diseases,Infectious Diseases and Others

Table 4: Gene Therapy Clinical Trials Worldwide (2007):Percentage Breakdown by Gene Type Transferred for Antigen, Cytokine, Tumor Suppressor, Growth Factor, Suicide, Deficiency and Others

Table 5: Gene Therapy Clinical Trials Worldwide (2007): Percentage breakdown by Vector Type for Adenovirus, Retrovirus, Naked/Plasmid DNA, Lipofection, Vaccinia Virus, Poxvirus, Adeno- associated Virus, and Others

Gene Therapy Industry in Europe and the US -A Comparison
7.RESEARCH AND DEVELOPMENT

Anti-Clotting Drug from GE Goats to Win Approval

British Midlands University to Reveal Genetic Code of Bacterium Causing Hospital Acquired Infection

Genetically Engineered BMPs to Facilitate Bone Formation in Orthopedic Surgeries

GE Finds Application in Obesity Control

Trubion Develops Advanced mAbs

New Study Reveals microRNA’s Role in Heart Failure

Cell-based Assays to Aid in Early Drug Discovery

Inhibition of SHIP Gene to Minimize Risk in Stem Cell Transplants

Drug Discovery to Employ Chemical Genetics

GE to Aid in the Discovery of New Enzyme Sources

Demand for Lactose-Free Products Boosts Enzymes Applications Market

8.MERGERS & ACQUISITIONS

RJH Industries Acquires Philippines Royal Oil

Monsanto Takes Over Aly Participacoes

Monsanto Acquires De Ruiter Seeds Group

Lydall Announces Acquisition of DSM Solutech

Biotie Completes Acquisition of elbion

Pfizer Animal Health Acquires Catapult Genetics

Monsanto Completes Marmot Acquisition

BioEnergy Takes Over Assets of OmniGene Bioproducts

BRAIN Takes Over Industrial Biotech Assets of MerLion Pharmaceuticals

MTS Health Investors Acquires DNA Diagnostic Center

Bayer HealthCare Takes Over Direvo Biotech

QIAGEN Completes Acquisition of Corbett Life Science

ChemVentures to Acquire BioFocus DPI Chemistry Facility

Nanobac Pharmaceuticals to Take Over DNAPrint Genomics

GlaxoSmithKline to Take Over Genelabs Technologies

Invitrogen Merges with Applied Biosystems

NitroMed Enters into Definitive Merger Agreement with Archemix

Monsanto Completes Acquisition of Delta & Pine Land

Inverness Medical Innovations Acquires Biosite

Avesta Biotherapeutics Takes Over Siegfried Biologics

Entelos Takes Over Iconix Biosciences

Illumina Takes Over Solexa

Celera Group Acquires Atria Genetics

CytoDyn Acquires Advanced Genetic Technologies

Takeda Europe to Take Over Paradigm Therapeutics

AmerisourceBergen Announces Acquisition of IgG of America

GlaxoSmithKline Plans Praecis Acquisition

9.RECENT INDUSTRY ACTIVITY

Eureka, Glycos Partner to Develop Bacterium for Biorefinery

Genzyme Acquires Rights to MabCampath, Fludara and Leukine

Quantel Announces Genetic Engineering Technology Support for Lasergraphics

USDA to Deregulate Syngenta’s GE Corn

Archer Daniels, Deere & Company and Monsanto to Form Partnership

Genzyme Collaborates with ICGEB

Veredus Partners with STMicroelectronics to Establish Bio-Application Lab

Invitrogen Gains License for Stem Cell Line

Millipore Enters into Agreement with Solabia

Advanced Cell Forms Joint Venture with CHA Biotech

Luminex Enters into Agreement with Mingyuan

ProGenTech Inks Agreement with Human Genetic Signatures

Monsanto and China National Seed Group Sign Agreement

Monsanto and Syngenta Sign Royalty-Bearing Licensing Agreement

Affymetrix Signs Definitive Agreement with Panomics

Sanofi-Aventis to Use Regeneron’s Genetic Modification Method

Monsanto to Build DEKALB Corn Seed Production Facility

Qatar Receives Grant to Augment Agro-Genetic Engineering Capacity

Monsanto Expands Jerseyville Facility

Sirtris Pharmaceuticals Obtains Approval for NamPRT

Origin Agritech Obtains License for Phytase Corn

Shenyang Xiehe Establishes Genetic Engineering Subsidiary

BioServe Enters into Alliance with DNAPrint Genomics

Evogene Teams Up with Ormat on Biodiesel

EMD and Dendritic Nanotechnologies Enter into License and Supply Agreement

AureoGen Biosciences Enters into Agreement with Takara Bio

Shanghai Wanxing Inks Agreement with Blue Blood Biotech

Stem Cell Sciences Signs Agreement with RIKEN Centre

Olympus and National Center for Biological Sciences Open New Facility

Biocentury Obtains Approval for Hybrid Cotton Seed in India

Novozymes to Expand Operation Base

Cell Therapeutics to Develop More Targeted Treatments for Cancer

10.PRODUCT/SERVICE LAUNCHES

Affymetrix Introduces MyGeneChip Program

Genomnz to Unveil DNA Testing Service

Whatman Introduces EasiCollect

Nanoxis Launches Membrane Protein

Few Important Terms Used in Genetic

Engineering
Chromosomes

Genome

Recombinant DNA

Retroviruses

Plasmids

Transgenic Animals and Plants

Gene Therapy


GLOBAL DIRECTORY

Abstract

The global outlook series on Genetic Engineering provides a collection of market briefs and concise summaries of research findings. The report offers a bird’s eye view of the industry, highlights latest developments, and discusses demand drivers, issues and concerns, and regulatory environment. Discussion on the industry’s most noteworthy regional market, the US, is amply detailed with unbiased research commentary to provide the reader a rudimentary understanding of the prevailing market climate. The report also provides select data on regional markets. Also included is an indexed, easy-to-refer, fact-finder directory listing the addresses, and contact details of 169 companies active in the market.

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