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Emerging Markets for Microfluidic Applications

Published by: Yole Developpement

Published: Aug. 1, 2009 - 206 Pages


Table of Contents


1 - EXECUTIVE SUMMARY

2 - INTRODUCTION

3-MICROFLUIDIC MARKETS 2009-2014

Market geographical distribution

Impact of microfluidics

Microfluidic applications

Microfluidic components market value and forecast

Compound Annual Growth Rates 2006- 2008 and 2009-2014

4- WHAT HAPPENED SINCE 2007

Microfluidics, a structured market

Market data versus EMMA2007 forecasts

Total diagnostics & Drug Delivery Markets 2006-2008; in M$

Microfluidic Devices Market Evolution 2006-2008, in M$

Market Breakdown in 2008

Materials by Application

Some product introduction

Investments in microfluidics since 2007

M&A in microfluidics since 2007

Life & Death

5- MICROFLUIDIC APPLICATIONS

Microfluidic Applications description

Microfluidics for Analytical devices

Cartridges for clinical and veterinary diagnostics

Microfluidic devices for Pharmaceutical and life science applications

Miniaturized cell based assays

Cell based assays

Miniaturized cell based assays

Applications

Ion channel drug discovery and screening

Patch-clamp

Cell transfection

Living or fixed cells

Primary cells and stem cells

Drug discovery programs

Toxicology and initial ADME studies

Shear flow analysis

Microfluidic devices for Point of Care

Capillary Electrophoresis chips

Microfluidic devices for Industrial and environmental testing

Microdispensers

Microdispensing

Microfluidics positioning in the Liquid Handling market

Microdispensers and workflow platforms

Overview of low liquid-handling systems

Microfluidic devices for drug delivery

6- MICROFLUIDIC TECHNOLOGIES

Microfluidics technologies Overview

Microfluidic Fluid motion strategy

Microfluidic Prototyping and Production

Materials by Application

Silicon as a substrate for Life Science applications

Glass as a substrate for Life Science applications

Polymers as a substrate for Life Science applications

Microfluidic technologies and materials

Synthesis

Microfluidic technologies: Main trends and conclusion

Functions integration

Functions integration, a main challenge

Functions needed for Life Science applications

A multi-disciplinary challenge

Material combination, a main challenge

Packaging techniques and their evolution

Packaging evolution

Advanced packaging: The challenges

From 2D to 3D…

Packaging for Life Science applications

DALSA Semiconducteur: Capillary Electrophoresis (CE) and DNA Separation

7- MICROFLUIDIC SUPPLY CHAIN

Competences required along the microfluidic industrial chain

Expectations of the microfluidic customers

Glass industrial supply chain

Polymer industrial supply chain

Silicon Industrial supply chain

IVD Industrial supply chain

8- MICROFLUIDIC VALUE CHAIN

Value chain analysis

Case Study: Microarray component value chain

Case Study: CALIPER Life Sciences LabChip

Case Study: Cost Analysis Caliper Labchip

Case Study: Caliper Labchip; Material Variation

Case Study: Caliper Labchip; Production location

Conclusion on the value chain

9- CONCLUSION

Abstract

Market and Technology Analysis of Microfluidic devices and technologies for Point of care diagnostics, Pharmaceutical and life science research, Analytical devices, Industrial & environmental testing, Drug delivery, and Clinical & veterinary diagnostics.

OBJECTIVES OF THE REPORT

The new Yole report presents microfluidics market data for 2006-2008 and market forecasts for 2009-2014 for life sciences and in-vitro-diagnostic applications, and provides detailed analysis of the market. A specific section is dedicated on the analysis of what happened over the last 3 years (including Alliances & mergers, new products, fund raising…), which are key elements to understand the actual and future microfluidic market.

MICROFLUIDIC APPLICATIONS

EMMA 09 report describes in detail the following applications:
  • Point of care diagnostics,
  • Pharmaceutical and life science research,
  • Analytical devices,
  • Industrial & environmental testing,
  • Drug delivery and clinical & veterinary diagnostics.
This analysis includes the market data, trends and drivers, key players and technologies. MICROFLUIDIC TECHNOLOGIES

The report provides an overview of the main fluid motion and manufacturing technologies. We describe, by application, the main material used (glass, polymer, silicon...), with their advantages and drawbacks.

MICROFLUIDIC SUPPLY CHAIN

The report describes the microfluidic supply chain, from R&D to commercialization and distribution. It shows for each type of material the main players and their role in the supply chain.

MICROFLUIDIC VALUE CHAIN

The analysis of the value chain provides an understanding of costs related to the different manufacturing steps (included packaging and quality control) in relation to the cost of the final product which includes reagent, commercialization and distribution costs.

MARKET

Microfluidic components are diverse and find many applications in the diagnostic and life Sciences fields. Microfluidics has entered the Life Sciences market as a key technology to provide solution to the market requirements in terms of:
  • Analysis automation
  • through:
  • high parallelisation
  • multiplex analysis
  • Reduced analysis cost by
  • lowering sample volume and reagents used
  • Faster analysis
  • Higher accuracy in fluid
  • dispensing.
In 2014, the market of microfluidic devices will exceed $3 billion. Drug discovery remains the first microfluidics market, and will continue to grow significantly as well. This is particularly true for the technologies enabling multiplexing. However, the largest growth is expected in the field of Point of Care diagnostics.

Today, some products are moving from research applications to the clinical diagnostics and point of care fields. However, this trend is limited due to the relative high manufacturing costs of many microfluidic devices and the fact that significant hurdles remain in the technology itself and its fusion into the healthcare system.

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