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The Global Specialty Excipient Market for Oral Solid-Dosage-Form Pharmaceuticals, 2005-2015 Volume IV: United States

Published by: Kline & Company, Inc.

Published: Aug. 15, 2009


Table of Contents


1. INTRODUCTION: UNITED STATES

Scope

Sources and methods

Organization

Units

Abbreviations

Limitations


2. EXECUTIVE SUMMARY


3. PHARMACEUTICAL INDUSTRY OVERVIEW: UNITED STATES

Trends

Research and development

Drug classes

Drug delivery forms

Advanced forms of delivery

The global market

Industry consolidation

The global prescription market

Leading drug companies

Research and development expenditures

The U.S. Market

Total sales

Leading therapeutic classes

Leading products

Over-the-counter drugs

Leading OTC companies

Other U.S. manufacturers

Background on oral solid-dosage forms

Major classes

Tablets

Capsules

Formulation platform: selecting excipients

Prescription drugs

Nonprescription drugs

Generic prescription drugs

Private-label or generic OTCs

4. SPECIALTY BINDERS AND FILLERS: UNITED STATES

Introduction

Estimated consumption

Supplier base

Outlook

4A. Alginates: United States

Introduction

Products

Consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

4B. Cellulosics: United States

Introduction

Estimated consumption

Suppliers

Outlook

Carboxymethylcellulose sodium

Introduction

Products

Estimated consumption

Customer base

Suppliers

Outlook

Appraisal

Ethyl cellulose

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Market Developments

Outlook

Appraisal

Hydroxypropyl cellulose

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

Hydroxypropyl methylcellulose

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

Methylcellulose

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

Microcrystalline cellulose

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal


4C. Dicalcium Phosphate: United States

Introduction

Products

Consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

4D. Directly Compressible Sucrose: United States

Introduction

Products

Consumption

Customer base

Suppliers

Channels of distribution

Market developments and trends

Outlook

Appraisal

4E. Lactose: United States

Introduction

Products

Consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

4F. Polyols: United States

Introduction

Estimated consumption

Suppliers

Outlook

Mannitol

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Market developments

Outlook

Appraisal

Sorbitol

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Market developments

Outlook

Appraisal

4G. Povidone: United States

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

4H. Starches: United States

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Market developments and trends

Outlook

Appraisal

4I. Xanthan Gum

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Market developments

Outlook

Appraisal


5. DISINTEGRANTS: UNITED STATES

Introduction

Estimated consumption

Supplier base

5A. Crospovidone: United States

Introduction

Estimated consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

5B. Croscarmellose Sodium: United States

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal

5C. Sodium Starch Glycolate: United States

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Outlook

Appraisal


6. LUBRICANTS: UNITED STATES

Introduction

Products

Magnesium stearate

Introduction

Products

Estimated consumption

Customer base

Suppliers

Channels of distribution

Market developments

Outlook

Appraisal


7. COATINGS: UNITED STATES

Introduction

Products

Estimated consumption

Customer base

Suppliers

Outlook

7A. Polymers/Film Formers: United States

Introduction

Products

Estimated consumption

Suppliers

Outlook

Polymethacrylates

Introduction

Products

Estimated consumption

Suppliers

Channels of distribution

Market developments and trends

Outlook

Hydroxypropyl methylcellulose

Introduction

Products

Estimated consumption

Suppliers

Channels of distribution

Market developments and trends

Outlook

Ethyl cellulose

Introduction

Products

Estimated consumption

Suppliers

Channels of distribution

Market developments and trends

Outlook

Cellulose acetate phthalate

Introduction

Products

Suppliers

Channels of distribution

Market developments and trends

Outlook

7B. Formulated Coatings: United States

Introduction

Products

Estimated consumption

Customer Base

Suppliers

Channels of distribution

Market developments

Outlook

7C. Coating Types: United States

Introduction

Film coatings

Instant-release sugar coatings

Suppliers

7D. Coating Functions: United States

Aesthetic/finishing coatings

Introduction

Properties

Polymers

Market developments and outlook

Protective coatings

Introduction

Properties

Polymers

Market developments

Enteric/delayed coatings

Introduction

Polymers

Sustained-release coatings

Introduction

Polymers

Market developments



8. SPECIALTY EXCIPIENTS USED IN MATRIX DELIVERY SYSTEMS: UNITED STATES

Introduction

Alginates

Cellulose acetate phthalate

Cellulose acetate and cellulose acetate butyrate

Hypromellose

Ethylcellulose

Hydroxypropylcellulose and hydroxyethyl cellulose

Polyvinyl acetate

Xanthan gum

Polymethacrylates

Polyethylene oxide

Carbomers

Drug-dissolution mechanism from carbopol polymers

Drug-delivery companies

Outlook


9. TECHNOLOGY TRENDS: UNITED STATES

Background

Equipment

Nanoparticles

Product development

Coatings

Modified-release products

Trends compared with cosmetics and toiletries

Outsourcing

Consolidation trend in contract services

Impact on excipient suppliers


10. REGULATORY MATTERS: UNITED STATES

Overview

FDA regulations

New excipients

U.S. Pharmacopoeia and national formulary

Global harmonization

Good manufacturing practices

Regulatory guidances

Industry involvement

11. SUPPLIERS: UNITED STATES

Specialty binders, fillers, matrix formers, disintegrants, and lubricants

Coatings

Supplier profiles

11A. BASF

Background

Organization and recent restructuring

Management and personnel

Sales and financial performance

Products

Excipient sales

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development

Outlook and appraisal

11B. Colorcon

Background

Acquisitions/partnership

Organization

Management and personnel

Sales and financial performance

Products

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development

Appraisal

11C. Eastman Chemical Company

Introduction

Products

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development

Outlook and appraisal

11D. International Specialty Products Inc.

Background

Organization

Sales and financial performance

Products

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development focus

Outlook

Appraisal

11E. JRS Pharma

Background

Organization

Management and personnel

Sales and financial performance

Products

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development focus

Outlook and appraisal

11F. Kerry Bio-Science

Background

Organization

Management and personnel

Sales and financial performance

Products

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development focus

Outlook

Appraisal

11G. Lubrizol

Background

Organization

Management and personnel

Sales and financial performance

Products

Functionality

Competitive position

Prices

Manufacturing facilities

Research and development focus

Outlook

11H. Mallinckrodt

Background

Organization

Management and personnel

Sales and financial performance

Products

Prices

Competitive position

Sales and marketing strategy

Manufacturing facilities

Market developments

Outlook and appraisal

11I. National Starch & Chemical Company

Background

Organization

Management and personnel

Sales and financial performance

Products

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development focus

Outlook and appraisal

11J. Roquette America

Background

Organization

Management and personnel

Sales and financial performance

Products

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development focus

Outlook

Appraisal

11K. SPI Pharma

Background

Organization

Management and personnel

Sales and financial performance

Products

Sales and marketing strategy

Competitive position

Manufacturing facilities

Research and development

Outlook

Appraisal


APPENDIX: LIST OF ORGANIZATIONS AND PERSONNEL INTERVIEWED


Abstract

This report provides a comprehensive examination of the complex and fragmented global market for oral solid-dosage products. Each regional volume features distinct and detailed analyses of five major specialty excipient categories and more than 25 individual products. Key industry dynamics and trends are also examined in each volume. Detailed assessments of specialty excipient procurement practices and business profiles of leading and niche specialty excipient and delivery technology suppliers are provided for each region. A forecast to 2015 completes each regional volume.

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