US Market for Spinal Implants, MIS, VCF, & Biomaterials 2007

Published by: iData Research, Inc.

Published: Apr. 1, 2007 - 359 Pages

Table of Contents

LIST OF FIGURES

LIST OF CHARTS

EXECUTIVE SUMMARY

1.1 U.S. MARKET FOR SPINAL IMPLANTS & BIOMATERIALS

1.2 TRADITIONAL CERVICAL FUSION FIXATION MARKET

1.3 TRADITIONAL THORACOLUMBAR FUSION FIXATION MARKET

1.4 INTERBODY FUSION MARKET

1.5 MOTION PRESERVATION MARKET

1.6 MIS FUSION MARKET

1.7 MIS VCF MARKET

1.8 SPINAL ELECTRICAL STIMULATION MARKET

1.9 BIOMATERIALS MARKET

1.10 LEADING COMPETITORS

RESEARCH METHODOLOGY

2.1 RESEARCH SCOPE

2.2 IDATA’S 9 STEP METHODOLOGY

Step 1 : Project Initiation & Team Selection

Step 2: Prepare Data Systems and Perform Secondary Research

Step 3: Preparation for Interviews & Survey design

Step 4: Performing Primary Research

Step 5: Research Analysis: Establishing Baseline Estimates

Step 6: Market Forecasting

Step 7: Identify Strategic Opportunities

Step 8: Final Review and Market Release

Step 9: Customer Feedback and Market Monitoring

U.S. SPINAL IMPLANT & BIOMATERIALS MARKET

3.1 INTRODUCTION

3.2 MARKET ANALYSIS AND FORECAST

3.2.1 Overview

3.2.2 Market Analysis by Segment

3.2.3 Trend Analysis and Forecast

3.3 MARKET DRIVERS AND LIMITERS

3.3.1 Drivers

3.3.2 Limiters

3.4 COMPETITIVE ANALYSIS

3.4.1 Market Share

3.4.2 Market Concentration

3.5 MERGERS AND ACQUISITIONS

3.5.1 Kyphon - St. Francis Medical Technology

3.5.2 Orthofix - Blackstone

3.5.3 Kyphon - Disc-O-Tech Medical Technologies

3.5.4 Zimmer - Endius

3.6 LITIGATION ISSUES

THE HUMAN SPINE

4.1 BASIC ANATOMY

4.2 SPINAL DISORDERS

4.2.1 Overview

4.2.2 Degenerative Disc Disease

4.2.3 Deformity

4.2.4 Trauma & Tumor

4.3 SPINAL DISORDER TREATMENTS

4.3.1 Decompression

4.3.2 Disectomy

4.3.3 Spinal Fusion

4.3.4 Corpectomy

4.3.5 Spinal Arthroplasty

SPINAL FUSION PROCEDURES

5.1 INTRODUCTION

5.2 INTERBODY FUSION DEVICES PROCEDURE VOLUMES

5.3 FUSION PROCEDURES BY SPINAL REGION

CERVICAL FIXATION MARKET

6.1 INTRODUCTION

6.2 PROCEDURE VOLUMES

6.2.1 Total Cervical Fixation Procedures

6.2.2 Cervical Anterior Fixation Procedures

6.2.3 Cervical Posterior Fixation Procedures

6.2.4 Cervical Bioresorbable Fixation Procedures

6.3 CERVICAL FIXATION MARKET ANALYSIS AND FORECAST

6.3.1 Cervical Fixation Market Overview

6.3.2 Cervical Anterior Constrained Fixation Market

6.3.3 Cervical Anterior Semi-Constrained Fixation Market

6.3.4 Cervical Anterior Dynamic Fixation Market

6.3.5 Cervical Anterior Bioresorbable Fixation Market

6.3.6 Cervical Posterior Wiring Fixation Market

6.3.7 Cervical Posterior Pedicle Fixation Market

6.4 MARKET DRIVERS AND LIMITERS

6.4.1 Market Drivers

6.4.2 Market Limiters

6.5 COMPETITIVE ANALYSIS

THORACOLUMBAR FIXATION MARKET

7.1 INTRODUCTION

7.2 PROCEDURE VOLUMES

7.2.1 Overview

7.2.2 Degenerative Procedure Volumes

7.2.3 Deformity Procedure Volumes

7.2.4 Trauma/Tumor Procedure Volumes

7.2.5 Posterior Plating Procedure Volumes

7.3 THORACOLUMBAR FUSION MARKET ANALYSIS & FORECAST

7.3.1 Market overview

7.3.2 Degenerative Market

7.3.3 Deformity Market

7.3.4 Trauma/Tumor Market

7.3.5 Posterior Plating Market

7.4 MARKET DRIVERS AND LIMITERS

7.4.1 Market Drivers

7.4.2 Market Limiters

7.5 COMPETITIVE ANALYSIS

INTERBODY DEVICE MARKET

8.1 INTRODUCTION

8.1.1 Overview

8.1.2 Approach Type

8.1.3 Material Type

8.2 PROCEDURE VOLUMES

8.2.1 Overview

8.2.2 Procedures by Material Type

8.2.3 Procedures by Approach

8.3 MARKET ANALYSIS AND FORECAST

8.3.1 Market Segmentation Overview

8.3.2 ALIF Market by Material

8.3.3 PLIF Market by Material

8.3.4 TLIF Market by Material

8.3.5 Cervical Market by Material

8.3.6 Corpectomy/VBR Market

8.3.7 Metal Market by Approach

8.3.8 PEEK Market by Approach

8.3.9 Machined Bone Market by Approach

8.4 MARKET DRIVERS AND LIMITERS

8.4.1 Market Drivers

8.4.2 Market Limiters

8.5 COMPETITIVE ANALYSIS

8.5.1 Overview

8.5.2 Competitors in the Non-bone Market

8.5.3 Competitors in the Machined Bone Market

MOTION PRESERVATION

9.1 OVERVIEW

9.1.1 The Technology

9.1.2 Market Summary

9.2 ARTIFICIAL DISCS

9.2.1 Procedure Volume

9.2.2 Market Analysis and Forecast

9.2.3 Drivers and Limiters

9.2.4 Competitive Analysis

9.3 DYNAMIC STABILIZATION

9.3.1 Introduction

9.3.2 Inter-spinous Device Market Analysis and Forecast

9.3.3 Leading Companies and Products

9.4 NUCLEUS REPLACEMENT

9.4.1 Introduction

9.4.2 Market Forecast

9.4.3 Leading Companies and Products

9.5 ANNULUS REPAIR

9.5.1 Procedure Penetration

9.5.2 Market Forecast

9.5.3 Leading Companies and Products

9.6 FACET ARTHROPLASTY

9.6.1 Procedure and Market Forecast

9.6.2 Leading Companies and Products

MINIMALLY INVASIVE SPINAL VCF MARKET

10.1 INTRODUCTION

10.1.1 Percutaneous Vertebroplasty

10.1.2 Kyphoplasty

10.2 PROCEDURE VOLUMES

10.2.1 Total VCF Procedures

10.2.2 Vertebroplasty Procedures

10.2.3 Kyphoplasty Procedures

10.3 VCF MARKET ANALYSIS AND FORECAST

10.3.1 Total VCF Market

10.3.2 Kyphoplasty Market

10.3.3 Vertebroplasty Market

10.4 MARKET DRIVERS AND LIMITERS

10.4.1 Market Drivers

10.4.2 Market Limiters

10.5 COMPETITIVE ANALYSIS

MIS SPINAL FUSION MARKET

11.1 INTRODUCTION

11.1.1 Overview

11.1.2 Systems Overview

11.1.3 Device Overview

11.2 PROCEDURE VOLUMES

11.2.1 Overview

11.2.2 Cannulated and Non-Cannulated Screw Procedures

11.3 MIS FUSION MARKET ANALYSIS AND FORECAST

11.3.1 Overview

11.3.2 MIS Thoracolumbar Fixation Market

11.3.3 MIS Interbody Market

11.3.4 MIS Percutaneous System Market

11.3.5 MIS Retractor System Market

11.4 MARKET DRIVERS AND LIMITERS

11.4.1 Market Drivers

11.4.2 Market Limiters

11.5 COMPETITIVE ANALYSIS

SPINAL ELECTRICAL STIMULATION MARKET

12.1 INTRODUCTION

12.2 UNIT VOLUMES

MARKET ANALYSIS AND FORECAST

12.2.1 Overview

12.2.2 Lumbar Electrical Stimulation Market

12.2.3 Cervical Electrical Stimulation Market

12.3 MARKET DRIVERS AND LIMITERS

12.3.1 Market Drivers

12.3.2 Market Limiters

12.4 COMPETITIVE ANALYSIS

SPINAL BIOMATERIALS MARKET

13.1 SPINAL BIOMATERIALS OVERVIEW

13.1.1 Introduction

13.1.2 Bone Graft Substitutes

13.1.3 Platelet Concentration System

13.1.4 Growth Factors

13.2 PROCEDURE VOLUMES

13.2.1 Bone Graft Substitutes

13.2.2 Autografts and Allografts

13.2.3 Synthetic and DBM Grafts

13.2.4 Spinal Growth Factors

13.2.5 Platelet Concentration Systems Procedures

13.3 MARKET ANALYSIS AND FORECAST

13.3.1 Market Overview

13.3.2 Allograft Market

13.3.3 DBM Market

13.3.4 Synthetic Market

13.3.5 Platelet Concentration System Market

13.3.6 Growth Factor Market

13.3.7 Stem Cell Graft Market Forecast

13.4 MARKET DRIVERS AND LIMITERS

13.4.1 Bone Graft Substitutes: Drivers & Limiters

13.4.2 Growth Factors: Drivers and Limiters

13.4.3 Platelet Concentration Systems: Drivers and Limiters

13.5 COMPETITIVE ANALYSIS

13.5.1 Competitors in the Spinal Bone Graft Substitute Market

13.5.2 Leading Competitors for Spinal Biomaterials

ABBREVIATIONS

LIST OF FIGURES

EXECUTIVE SUMMARY

RESEARCH METHODOLOGY

U.S. SPINAL IMPLANT & BIOMATERIALS MARKET

Figure 3-1 - Total Spinal Implant, MIS & Biomaterials Market, U.S., 2003- 2013

Figure 3-2 - Spinal Implant and Biomaterial Market Growth Rates, U.S., 2003- 2013

Figure 3-3 - Spinal Implant and Biomaterials Market Drivers and Limiters, U.S., 2006

Figure 3-4 - Spinal Implant and Biomaterials Market Share, US., 2006

Figure 3-5 - Spinal Implants and Biomaterials Market Concentration Based on the Herfindahl Index, U.S., 2003-2013

The Human Spine

Spinal Fusion Procedures

Figure 5-1 - Total Interbody Procedures by Approach, U.S., 2003-2013

Figure 5-2 - Total Spinal Fusion Procedures, U.S., 2003-2013

Figure 5-3 - Total Instrumented Spinal Fusions, U.S., 2003-2013

Cervical Fixation Market

Figure 6-1 - Cervical Fixation Procedure Percentages, U.S., 2003-2013

Figure 6-2 - Total Cervical Fixation Procedures, U.S., 2003-2013

Figure 6-3 - Cervical Anterior Fixation Procedure Percentages, U.S., 2003- 2013

Figure 6-4 - Cervical Anterior Fixation Proceudres by Segment, U.S.,2003- 2013

Figure 6-5 - Cervical Posterior Fixation Procedure Percentages, U.S., 2003- 2013

Figure 6-6 - Cervical Posterior Fixation Procedures by Segment, U.S., 2003- 2013

Figure 6-7 - Cervical Anterior Bioreabsorbable Fixation Procedures, U.S., 2005-2013

Figure 6-8 Cervical Fixation Market; Segmentation Percentages, U.S., 2003- 2013

Figure 6-9 - Total Cervical Fixation Market, U.S., 2003-2013

Figure 6-10 - Cervical Anterior Fixation Market Percentages, U.S., 2003-2013

Figure 6-11 - Cervical Anterior Market by Segment, U.S., 2003-2013

Figure 6-12 - Cervical Posterior Market; Segmentation Percentages, U.S., 2003-2013

Figure 6-13 Cervical Posterior Fixation Market, U.S., 2003-2013

Figure 6-14 - Cervical Anterior Constrained Fixation Market, U.S., 2003-2013

Figure 6-15 - Cervical Anterior Semi-Constrained Fixation Market, U.S., 2003-2013

Figure 6-16 Cervical Anterior Dynamic Fixation Market, US., 2003-2013

Figure 6-17 - Cervical Anterior Bioresorbable Fixation Market, U.S., 2005- 2013

Figure 6-18 - Cervical Posterior Wiring Fixation Market, U.S., 2003-2013

Figure 6-19 - Cervical Posterior Pedicle Screw/Rod Fixation Market, U.S., 2003-2013

Figure 6-20 - Cervical Fixation Market Drivers and Limiters, U.S., 2003-2013

Figure 6-21 - Cervical Fixation Market Share, U.S., 2006

THORACOLUMBAR FIXATION MARKET

Figure 7-1 - Thoracolumbar Procedure Percentages Segmented by Indication, U.S., 2003-2013

Figure 7-2 - Total Thoracolumbar Fixation Procedures, U.S., 2003-2013

Figure 7-3 -Thoracolumbar Degenerative Anterior Plating & Posterior Fixation Procedure Volumes, U.S., 2003-2013

Figure 7-4 - Thoracolumbar Fixation Procedures by Levels Fused, U.S., 2003- 2013

Figure 7-5 - Thoracolumbar Deformity Fixation Procedures, U.S., 2003-2013

Figure 7-6 - Thoracolumbar Trauma/Tumor Fixation Procedure Volumes, U.S., 2003-2013

Figure 7-7-Trauma/Tumor/Deformity Posterior Plating Procedures, U.S., 2003- 2013

Figure 7-8 - Thoracolumbar Market Share, U.S., 2003-2013

Figure 7-9 - Total Thoracolumbar Fusion Fixation Market, U.S., 2003-2013

Figure 7-10- Thoracolumbar Degenerative Market Segmentation and Share, U.S., 2003-2013

Figure 7-11 - Thoracolumbar Degenerative Anterior Plate Market Forecast, U.S., 2003-2013

Figure 7-12 -Degenerative Posterior Fixation Market, U.S., 2003-2013

Figure 7-13 - Degenerative Level Share Breakdown, U.S., 2003-2013

Figure 7-14 - Degenerative Single Level Market, U.S., 2003-2013

Figure 7-15 - Degenerative Double Level Market, U.S., 2003-2013

Figure 7-16 - Degenerative Multi-level Market, U.S., 2003-2013

Figure 7-17 - Deformity Thoracolumbar Fixation Market, U.S., 2003-2013

Figure 7-18 - Truama/Tumor Fixation Market, U.S., 2003-2013

Figure 7-19 - Posterior Plating Fixation Market, U.S., 2003-2013

Figure 7-20 - Posterior Plating Penetration, U.S., 2003-2013

Figure 7-21 - Overview of Market Drivers and Limiters for Thoracolumbar Fixation, U.S

Figure 7-22 - Thoracolumbar Fusion Fixation Market Share, U.S., 2006

INTERBODY DEVICE MARKET

Figure 8-1 - Interbody Procedure Percentages by Approach, U.S., 2003-2013

Figure 8-2 - Total Interbody Procedures By Approach, U.S., 2006-2013

Figure 8-3 - Interbody Procedure Percentages by Material, , U.S., 2003-2013

Figure 8-4 Total Interbody Procedures by Material Type, U.S., 2003-2013

Figure 8-5 - Interbody PEEK Device Procedure Percentages by Approach, U.S., 2003-2013

Figure 8-6 -Interbody PEEK Device Procedures by Approach, U.S., 2003-2013

Figure 8-7 - Interbody Metal Device Procedure Percentages by Approach, U.S., 2003-2013

Figure 8-8 -Interbody Metal Device Procedures by Approach Type, U.S., 2003- 2013

Figure 8-9 - Interbody Machined Bone Procedure Percentages by Approach, Percentages, U.S., 2003-2013

Figure 8-10 -Interbody Machined Bone Procedures by Approach, U.S., 2003- 2013

Figure 8-11 - ALIF Procedure Percentages by Material, U.S., 2003-2013

Figure 8-12 - ALIF Procedures by Material, U.S., 2003-2013

Figure 8-13 - PLIF Procedure Percentages by Approach, U.S., 2003-2013

Figure 8-14 - PLIF Procedures by Material Type, U.S., 2003-2013

Figure 8-15 - TLIF Procedure Percentages by Material Type, U.S., 2003-2013

Figure 8-16 - TLIF Procedures by Material Type, U.S., 2003-2013

Figure 8-17 - Cervical Interbody Procedure Percentages by Approach Type, U.S., 2003-2013

Figure 8-18 - Cervical Interbody Procedures by Matertial, U.S., 2003-2013

Figure 8-19 - Interbody Device Market Percentages by Approach, U.S., 2003- 2013

Figure 8-20 - Interbody Device Market by Approach, U.S., 2003-2013

Figure 8-21 - Interbody Device Market Percentages Segmented by Material, U.S., 2003-2013

Figure 8-22 - Interbody Devices Market Segmented by Material, US., 2003- 2013

Figure 8-23 - ALIF Market Percentages by Material, U.S., 2003-2013

Figure 8-24 -ALIF Market by Material U.S., 2003-2013

Figure 8-25 - ALIF Market by Material, Metal, U.S., 2003-2013

Figure 8-26 - ALIF Market By Material, PEEK, U.S., 2003-20013

Figure 8-27 - ALIF Market By Material, Machined Bone, U.S., 2003-2013

Figure 8-28 - PLIF Market Percentages by Material, U.S., 2003-2013

Figure 8-29 -PLIF Market by Material, U.S., 2003-2013

Figure 8-30 - PLIF Market by Material, Metal, U.S., 2003-2013

Figure 8-31 - PLIF Market By Material, PEEK, U.S., 2003-20013

Figure 8-32 - PLIF Market By Material, Machined Bone, U.S., 2003-2013

Figure 8-33 - TLIF Market Percentages by Material, U.S., 2003-2013

Figure 8-34 -TLIF Market by Material U.S., 2003-2013

Figure 8-35 - TLIF Market by Material, Metal, U.S., 2003-2013

Figure 8-36 - TLIF Market by Material, PEEK, U.S., 2003-20013

Figure 8-37 - TLIF Market by Material, Machined Bone, U.S., 2003-2013

Figure 8-38 - CIF Market Percentages by Material, U.S., 2003-2013

Figure 8-39 -CIF Market by Material U.S., 2003-2013

Figure 8-40 - CIF Market by Material, Metal, U.S., 2003-2013

Figure 8-41 - CIF Market by Material, PEEK, U.S., 2003-20013

Figure 8-42 - CIF Market by Material, Machined Bone, U.S., 2003-2013

Figure 8-43 - Corpectomy/VBR Cage Market, U.S., 2003-2013

Figure 8-44 - Interbody Metal Device Market Percentages by Approach U.S., 2003-2013

Figure 8-45 - Interbody Metal Device Market by Approach, U.S., 2003-2013

Figure 8-46 - Interbody PEEK Market Percentages by Approach, U.S., 2003- 2013

Figure 8-47 - Interbody PEEK Device Market by Approach, U.S., 2003-2013

Figure 8-48 - Interbody Machined Bone Market Percentages by Approach, U.S., 2003-2013

Figure 8-49 -Interbody Machined Bone Device Market by Approach, U.S., 2003-2013

Figure 8-50 - Interbody Device Market Drivers and Limiters, U.S.

Figure 8-51 - Leading Competitors in the Total Interbody Devices Market, Market Shares, U.S., 2006

Figure 8-52 - Leading Competitors in the Non-bone Interbody Devices Market, Market Shares, U.S., 2006

Figure 8-53 - Leading Competitors in the Machined Bone Interbody Devices Market, Market Shares, U.S., 2006

MOTION PRESERVATION

Figure 9-1 - Motion Preservation Market, U.S., 2004-2013

Figure 9-2 - Artitifical Disc Procedures and Fusion Procedure Penetration, U.S., 2004-2013

Figure 9-3 -Artificial Disc Market by Type, U.S., 2004-2013

Figure 9-4 - Lumbar Artificial Disc Market, U.S., 2004-2013

Figure 9-5 - Cervical Artificial Disc Market, U.S., 2007-2013

Figure 9-6 - Artificial Discs Market Drivers and Limiters, U.S., 2006

Figure 9-7 - Leading Competitors for Artificial Discs, U.S., 2006

Figure 9-8 -Inter-spinous Dynamic Stabilization Market, U.S., 2005-2013

Figure 9-9 Emerging Inter-spinous Products, U.S.,2006-2013

Figure 9-10 -Leading Competitors for Inter-spinous Devices, U.S., 2006

Figure 9-11 - Nucleus Replacement Device Market, U.S., 2010-2013

Figure 9-12 - Emerging Nucleus Replacement Devices, U.S., 2006-2013

Figure 9-13 - Annular Repeair Market Forecast, U.S., 2007-2013

Figure 9-14 - Annular Repair Market, U.S., 2007-2013

Figure 9-15 - Emerging Annular Repair Products, U.S., 2006-2013

Figure 9-16 - Facet Arthroplasty Procedure Penetration Rates, U.S., 2009-2013 251

Figure 9-17- Facet Arthroplasty Market, U.S., 2009-2013

Figure 9-18 - Emerging Facet Arthroplasty Devices, U.S., 2006-2013

MINIMALLY INVASIVE SPINAL VCF MARKET

Figure 10-1 - Total VCF Procedure Segmentation Percentages, U.S., 2003- 2013

Figure 10-2 - Total VCF Procedures by Type, U.S., 2003-2013

Figure 10-3 - Vertebroplasty Procedures, U.S., 2003-2013

Figure 10-4 - Kyphoplasty Procedures and Fractures, U.S., 2003-2013

Figure 10-5 -VCF Market by Type, U.S., 2003-2013

Figure 10-6 - Kyphoplasty Market, U.S., 2003-2013

Figure 10-7 - Vertbroplasty Market, U.S., 2003-2013

Figure 10-8 - VCF Market Drivers and Limiters, U.S., 2003-2013

Figure 10-9 - Leading Competitors,VCF Market Share, U.S., 2006

MIS SPINAL FUSION MARKET

Figure 11-1 - Total MIS Fusion Procedures, U.S., 2003-2013

Figure 11-2 - Total MIS Procedure Percentages Based on Pedicle Screw Types, U.S., 2003-2013

Figure 11-3 - Total MIS Cannulated Pedicle Screw Procedure Percentages Specific to Retractor Systems, U.S., 2003-2013

Figure 11-4 - Total MIS Pedicle Screw Procedures, U.S., 2003-2013

Figure 11-5 - MIS Fusion Market by Device, U.S., 2003-2013

Figure 11-6 - MIS Fusion Market by System, U.S., 2003-2013

Figure 11-7 - MIS Thoracolumbar Fixation Market., U.S., 2003-2013

Figure 11-8 - MIS Cannulated Screw Market. U.S., 2003-2013

Figure 11-9 - MIS Non-Cannulated Screw Market. U.S., 2003-2013

Figure 11-10 - MIS Interbody Market, U.S., 2003-2013

Figure 11-11 - MIS Percutaneous Market, U.S., 2003-2013

Figure 11-12 - MIS Retractor System Market Segmented by Device, U.S., 2003-2013

Figure 11-13 - MIS Retractor Cannulated Screw Market, U.S., 2003-2013

Figure 11-14 - MIS Retractor Non-Cannulated Market, U.S., 2003-2013

Figure 11-15 - MIS Fusion Market Drivers and Limiters, U.S., 2006

Figure 11-16 - Leading Competitors, MIS Spinal Fusion Devices, Market Share, U.S., 2006

SPINAL ELECTRICAL STIMULATION MARKET

Figure 12-1 - Electrical Stimulation Unit Volumes, U.S., 2003-2013

Figure 12-2 - Total Electrical Stimulation Market, U.S., 2003-2013

Figure 12-3 - Lumbar Electrical Stimulation Market, U.S., 2003-2013

Figure 12-4 - Cervical Electrical Stimulation Market, U.S., 2003-2013

Figure 12-5 - Electrical Stimulation Market Drivers and Limiters, U.S., 2006

Figure 12-6- Leading Competitors, Spinal Electrical Stimulation Devices, Market Share, 2006, U.S.

SPINAL BIOMATERIALS MARKET

Figure 13-1 - Bone Graft Substitutes Properties, U.S.

Figure 13-2 - Bone Graft Substitutes, Procedure Volumes, U.S., 2003-2013

Figure 13-3 - Allograft and Autograft Procedure Volumes, U.S., 2003-2013

Figure 13-4 - Synthetic and DBM Graft Procedure Volumes and Growth, U.S., 2003-2013

Figure 13-5 - Total Spinal Growth Factor Procedure Volumes, U.S., 2003-2013 328

Figure 13-6 - Thoracolumbar and Cervical Growth Factor Procedure Volumes, U.S., 2003-2013

Figure 13-7 - Platelet Concentration Procedure Volumes, U.S., 2003-2013

Figure 13-8 - Total Spinal Biomaterials Market, U.S., 2003-2013

Figure 13-9 - Allograft Market, U.S., 2003-2013

Figure 13-10 - DBM Market, U.S., 2003-2013

Figure 13-11 - Synthetic Market, U.S., 2003-2013

Figure 13-12 - Platelet Concentration System Market, U.S., 2003-2013

Figure 13-13 - Total Growth Factor Market, U.S., 2003-2013

Figure 13-14 - Thoracolumbar Growth Factor Market, U.S., 2003-2013

Figure 13-15 - Cervical Growth Factor Market, U.S., 2003-2013

Figure 13-16 Stem Cell Based Graft Market, U.S., 2006-2013

Figure 13-17 - Bone Graft Substitute Market Drivers & Limiters, U.S., 2006

Figure 13-18 Growth Factor Market Drivers & Limiters, U.S., 2006

Figure 13-19 - Leading Competitors in the Bone Graft Substitutes Market, U.S., 2006

Figure 13-20 Leading Competitors in the Spinal Biomaterials Market, U.S., 2006

ABBREVIATIONS

LIST OF CHARTS

EXECUTIVE SUMMARY

Chart 1-1 Spinal Implants & Biomaterials Market by Segment, U.S., 2006

Chart 1-2 - Traditional Cervical Fixation Market, U.S., 2003-2013

Chart 1-3 - Traditional Thoracolumbar Fixation Market, U.S., 2003-2013

Chart 1-4 - Interbody Fusion Market, U.S., 2006

Chart 1-5 - Spinal Biomaterials Market, U.S., 2003-2013

Chart 1-6 - Leading Competitors, Spinal Implant and Biomaterials U.S., 2006

RESEARCH METHODOLOGY

U.S. SPINAL IMPLANT & BIOMATERIALS MARKET

Chart 3-1 - Spinal Implant and Biomaterials Market, U.S., 2006

Chart 3-2 - Spinal Implant and Biomaterials Market, U.S., 2003-2013

Chart 3-3 - Spinal Implant and Biomaterials Market Trends, U.S., 2003-2013

Chart 3-4 - Spinal Implant and Biomaterials Market Trends Excluding Motion Preservation, U.S., 2003-2013

Chart 3-5 - Leading Competitors, Spinal Implant and Biomaterials Market Share, U.S., 2006

Chart 3-6 - Spinal Implants and Biomaterials Market Concentration based on the Herfindahl index, U.S., 2003-2013

The Human Spine

Spinal Fusion Procedures

Chart 5-1 - Total Interbody Procedures, U.S., 2006

Cervical Fixation Market

Chart 6-1 - Total Cervical Fixation Market Forecast, U.S., 2003-2013

Chart 6-2 - Cervical Anterior Fixation Market, U.S., 2003-2013

Chart 6-3 - Cervical Posterior Fixation Market Forecast, U.S., 2003-2013

Chart 6-4 - Cervical Anterior Constrained Fixation Market Forecast, U.S., 2003-2013

Chart 6-5 - Cervical Anterior Semi-Constrained Fixation Market Forecast, U.S., 2003- 2013

Chart 6-6 - Cervical Anterior Dynamic Fixation Market Forecast, U.S., 2003-201382

Chart 6-7 - Cervical Anterior Bioresorbable Fixation Market Forecast, U.S., 2003- 2013

Chart 6-8 - Cervical Posterior Wiring Fixation Market Forecast, U.S., 2003-201387

Chart 6-9 - Cervical Posterior Pedicle Screw/Rod Fixation Market Forecast

THORACOLUMBAR FIXATION MARKET

Chart 7-1 - Total Thoracolumbar Fusion fixation Market Forecast, U.S., 2003-2013

Chart 7-2 - Thoracolumbar Degenerative Market Forecast, U.S., 2003-2013

Chart 7-3 - Thoracolumbar Anterior Plate Market Forecast, U.S., 2003-2013

Chart 7-4 - Degenerative Posterior Fixation Market Forecast, U.S., 2003-2013

Chart 7-5 - Deformity Thoracolumbar Fixation Market Forecast, U.S., 2003-2013123

Chart 7-6 - Truama/Tumor Fixation Market Forecast, U.S., 2003-2013

Chart 7-7 - Posterior Plating Fixation Market, U.S., 2003-2013

INTERBODY DEVICE MARKET

Chart 8-1 - Interbody Market Trends by Approach, Growth Rates, U.S., 2003-2013

Chart 8-2 - Interbody Market by Approach, U.S., 2003-2013

Chart 8-3 - Interbody Market by Material, Growth Rates, U.S., 2003-2013

Chart 8-4 - Interbody Market by Material, U.S., 2003-2013, U.S., 2003-2013

Chart 8-5 - ALIF Market By Material, Growth Rates, U.S., 2003-2013

Chart 8-6 - ALIF Market by Material, U.S., 2003-2013

Chart 8-7 - PLIF Market Trends By Material, Growth Rates, U.S., 2003-2013

Chart 8-8 - PLIF Market by Material, U.S., 2003-2013

Chart 8-9 - TLIF Market Trends By Material, Growth Rates, U.S., 2003-2013

Chart 8-10 - TLIF Market by Material, U.S., 2003-2013

Chart 8-11 - CIF Market By Material, Growth Rates, U.S., 2003-2013

Chart 8-12 - CIF Market by Material, U.S., 2003-2013

Chart 8-13 - Corpectomy/VBR Cage Market, U.S., 2003-2013

Chart 8-14 - Interbody Metal Device Market by Approach, Trends and Growth Rates, U.S., 2003-2013

Chart 8-15 - Interbody Metal Device Market by Approach, U.S., 2003-2013

Chart 8-16 - Interbody PEEK Device Market by Approach, Trends andGrowth Rates, U.S., 2003-2013

Chart 8-17 - Interbody PEEK Device Market by Approach, U.S., 2003-2013

Chart 8-18 - Interbody Machined Bone Device Market by Approach, Trends and Growth Rates, U.S., 2003-2013

Chart 8-19 - Interbody Machined Bone Device Market by Approach, U.S., 2003-2013

MOTION PRESERVATION

Chart 9-1 - Motion Preservation Market, U.S., 2004-2013

Chart 9-2 -Artificial Disc Market by Type, U.S., 2004-2013

Chart 9-3 - Lumbar Artificial Disc Market, U.S., 2004-2013

Chart 9-4 - Cervical Artificial Disc Market, U.S., 2007-2013

Chart 9-5 - Inter-spinous Dynamic Stabilization Market, U.S., 2005-2013

Chart 9-6 - Nucleus Replacement Device Market, U.S., 2010-2013

Chart 9-7 - Annular Repair Market, U.S, 2007-2013

Chart 9-8 - Facet Arhtroplasty Market, U.S., 2009-2013

MINIMALLY INVASIVE SPINAL VCF MARKET

Chart 10-1 - VCF Market, U.S., 2003-2013

Chart 10-2 - Kyphoplasty Market, U.S., 2003-2013

Chart 10-3 - Vertebroplasty Market, U.S., 2003-2013

MIS SPINAL FUSION MARKET

Chart 11-1 - MIS Fusion Market by Device, U.S., 2003-2013

Chart 11-2 - MIS Fusion Market by System, U.S., 2003-2013

Chart 11-3 - MIS Thoracolumbar Market, U.S., 2003-2013

Chart 11-4 - MIS Cannulated Pedicle Screw Market, U.S., 2003-2013

Chart 11-5 - Non-cannulated MIS Fusion Market, U.S., 2003-2013

Chart 11-6 - MIS Interbody Fusion Market, U.S., 2003-2013

Chart 11-7 - MIS Percutaneous Market, U.S., 2003-2013

Chart 11-8 - MIS Retractor Market, U.S., 2003-2013

Chart 11-9 - MIS Retyractor Pedicle Srcrew Market, U.S., 2003-2013

SPINAL ELECTRICAL STIMULATION MARKET

Chart 12-1 - Total Electrical Stimulation Market, U.S., 2003-2013

Chart 12-2- Lumbar Electrical Stimulation Market, U.S., 2003-2013

Chart 12-3 - Cervical Electrical Stimulation Market, U.S., 2003-2013

SPINAL BIOMATERIALS MARKET

Chart 13-1 - Spinal Biomaterial Market Forecast, U.S., 2003-2013

Chart 13-2 - Biomaterials Market Value Share by Product, U.S., 2006 & 2013

Chart 13-3 - Allograft Market Forecast, U.S., 2003-2013

Chart 13-4 - DBM Market Forecast, U.S., 2003-2013

Chart 13-5 - Synthetic Market Forecast, U.S., 2003-2013

Chart 13-6 - Platelet Concentration Systems Market Forecast, U.S., 2003-2013 . 342

Chart 13-7 - Total Growth Factor Market Forecast, U.S., 2003-2013

Chart 13-8 -Thoracolumbar Growth Factor Market Forecast, U.S., 2003-2013

Chart 13-9 - Cervical Growth Factors Market Forecast, U.S., 2003-2013

ABBREVIATIONS

Abstract

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