|
|
Antibodies in Oncology: Drug Pipeline Update 2009Published by: BioSeeker Group AB Published: Jan. 20, 2009 Table of Contents
AbstractExecutive SummaryThe commercial and therapeutic success of antibodies like Rituxan, Avastin, and Erbitux will force the industry to look into the next generation of therapeutic antibodies, preparing themselves for the second wave in the lucrative field of therapeutic antibodies. Today, there are more than 330 companies plus partners developing more than 450 antibody based oncology drugs in more than 880 developmental projects. In addition, the accumulated number of ceased drugs over the last three years amount to another 192 drugs. In all, these antibody based drugs target around 71 different cancer indications. The number of antibody targets has increased to over 240 described molecular targets in just a few years. These targets are further categorized on the CD-ROM by 56 classifications of molecular function and with pathway referals to BioCarta, KEGG and NetPath. Read more below on how the Antibody in Oncology: Drug Pipeline Update is organized. How May Drug Pipeline Update Be of Use? Show investors/board/management that you are right on top of drug development progress in your therapeutic area. Find competitors, collaborations partners, M&A candidates etc. Jump start competitive drug intelligence operations Excellent starting point for world wide benchmarking Compare portfolio and therapy focus with your peers Speed up pro-active in-/out licensing strategy work Fast and easy way of tracking drugs using search engines; just one click from inside the application and you may search the World Wide Web and PubMed for any drug. Drug Pipeline Update is delivered to you as a CD-ROM application, which requires no installation on your computer. Please read more about application features and system requirements below. Drug Pipeline Update at a Glance Investigators Includes 332 principal investigators plus their collaborators. There is direct access from inside the application to web pages of all principal investigators. Note: You are able to sort and find drugs according to investigators and partners from drop-down menus in the application. You may also sort and find drugs according to country of investigator. Drug name & Synonyms Lists commercial, generic and code names for drugs. In all more than 700 names Developmental stage This Drug Pipeline Update contains 455 antibody drugs in active development and 889 developmental projects: #76 projects have reached market approval #3 projects have been registered #4 projects in pre-registration #39 projects in Phase III #272 projects in Phase II #201 projects in Phase I #268 projects in Preclinical #26 projects in other developmental stages Note: You are able to sort and find drugs according to developmental stage from drop-down menu in the application. Indications Included antibody drugs are in development for 181 different indications, where of 71 are different cancer indications. All antibodies are in development for the treatment of cancer. Note: You are able to sort and find drugs according to type of indication from drop-down menu in the application. Targets Identified drugs are linked to more than 243 different targets, divided into 37 classifications of molecular function:
Target Expression Profile Direct links are provided from inside the application to 211 protein expression profiles of 148 drug targets in various human tissues and cancer types, cell lines and primary cells, including up to:
Mechanism In total there are 269 different drug mechanism of action represented in this Drug Pipeline Update. Note: You are able to sort and find drugs according to mechanism of action from drop-down menu in the application. Compound All antibody based Drug Profile Progress analysis and review of drug development. A typical drug profile reports on, depending on stage of development and available information: Drug Name & Synonyms Presentation of drug name and synonyms Principal Investigator & Partners Presentation of principal investigator and partners Target and Molecular Function of Target Described target(s) is/are presented with: Official Gene Symbol - Official Gene Name [Species/Homo Sapiens] - Molecular Function Target Localization Described target(s) is/are presented with primary and alternate localizations. Target Expression Profiles Links to protein expression profile(s) of target(s) in various human tissues, cell lines and primary cells, including up to:
Mechanism Drug mechanism of action Developmental Projects Summary field of developmental projects for the drug, including indication, developmental stage and status. Example: Cancer, myeloma - Phase II Clinical Trial - Active Cancer, prostate - Phase III Clinical Trial - Ceased Drug Description Short introduction to drug Compound Data Compound type, Chemical name, CAS Number and molecular weight Patent Data Available patent information related to the drug is presented here. Business & Markets Collaborations and deals Approvals and submissions Analyst comments Phase III Data Available Phase III development data, developmental history and scientific data. Phase II Data Available Phase II development data, developmental history and scientific data. Phase I Data Available Phase I development data, developmental history and scientific data. Preclinical Data Available preclinical development data, developmental history and scientific data. Licensing Information Availability for licensing Application Features Use 13 different parameters, available in drop-down menus, to find and sort among drugs
Get Full Details About This Report >> |
|
|||
|
About MarketResearch.com
|
||||