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Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015

Published by: Wintergreen Research

Published: Feb. 18, 2009 - 723 Pages


Table of Contents


MICROSCOPE EXECUTIVE SUMMARY

Microscope Market Driving Forces

Microscope Market Shares

Carl Zeiss ES-8

Microscope Market Forecasts

Research And Industrial Use Of Imaging

Japan's Leading National Institute Orders Powerful

Microscope from FEI

Every Major Developed Country Needs To Invest

Nanotechnology Microscopes

King Abdullah University of Science and Technology and

FEI Team for Nanoscience Facility

Japan's Leading National Institute Orders Powerful

Microscope from FEI

FEI's Titan Krios TEM Selected by Leading Life Science

Research Centers in Asia

IBM Microscope 100 Million Times Finer

Resolution Than Current MRI

1. MICROSCOPES MARKET DESCRIPTION AND MARKET DYNAMICS

1.1 Electron Microscope

1.1.1 Electron Microscope Economic Driving Forces

1.1.2 Transmission Electron Microscope (TEM)

1.1.3 TEM Uses Magnetic Lenses Guide the Electrons

1.1.4 Scanning Electron Microscope

1.1.5 TEM and SEM used for Nanotechnology

1.1.6 Nanotechnology: Using a Bottom-Up Approach Larger Structures Are Built Or Grown Atom By Atom Or Molecule By Molecule

1.2 Atomic Force Microscopy

1.2.1 AFM

1.2.2 Force Spectroscopy

1.3 Emerging Topics In Microscopy And Microanalysis

1.3.1 Intravital Two-Photon Microscopy

1.3.2 Understanding Of Interactions Between Organic And Mineral Interfaces

1.3.3 Routine Application Of Imaging, Spectroscopy And Diffraction Techniques For The Analysis Of Individual Nanostructured Materials

1.3.4 Irradiation By Energetic Electrons

1.3.5 Focused Ion Beam (FIB) Science And Technology

1.3.6 Semiconductor Quantum Dots (QDs)

1.3.7 Advances of Electron Backscatter Diffraction

1.3.8 Development Of Nano-Materials

1.3.9 Approaches To Achieve Sub-Light Wavelength Resolution

1.3.10 Advanced Coating Stability

1.3.11 Quantitative Atom-Probe Tomography (APT)

1.3.12 Electron Microscopy Structural Issues

1.4 Microscope Frames And Accessory Modules

1.4.1 Fluorescent Or Phase Microscope Modules

1.4.2 Modern Materials, Lubricants And Machine Tools

1.5 Microscope Market Segments

1.5.1 Bio-Med Microscope Market

1.5.2 Clinical Microscope Market

1.5.3 Industrial Microscope Market

1.5.4 Electronics Market Microscopes

1.5.5 Metalurgical Microscopes

1.6 Stereomicroscopy Need To Measure On-Axis

1.6.1 Stereo Microscopes

1.7 Compound Microscopes

1.8 Microscopy Illumination Methods

1.9 Microscopy Imaging Techniques

1.10 Nanotechnology Paves The Way For A Revolution In Materials

2. MICROSCOPE MARKET SHARES AND MARKET FORECASTS

2.1 Microscope Market Driving Forces

2.2 Microscope Market Shares

2.2.1 Carl Zeiss

2.3 Microscope Market Forecasts

2.4 Optical Microscope and Electron Microscope Market Segments

2.5 Electron Microscope Transmission (TEM) and Scanning (SEM) Markets

2.5.1 Electron Microscope Transmission Electron Microscopy (TEM) and Scanning Electron Microscope (SEM) Market Shares

2.5.2 Electron Microscope Transmission Electron Microscopy (TEM) and Scanning Electron Microscope (SEM) Market Forecasts

2.5.3 Hitachi S-5500 In-lens FE-SEM

2.5.4 FEI

2.5.5 Japan's Leading National Institute Orders Powerful Microscope from FEI

2.5.6 King Abdullah University of Science and Technology and FEI Company Team to Create Major Nanoscience Facility

2.5.7 Jeol Scanning Electron Microscopes

2.5.8 JEOL

2.5.9 JEOL Electron Optics

2.5.10 JEOL Analytical Electron Microscope Instruments

2.5.11 Carl Zeiss ORION™ Helium Ion Microscope

2.6 TEM and SEM Research Electron Microscope Market Forecasts

2.6.1 Electron Microscopes Are Helping Materials Scientists

2.6.2 Electron Microscope TEM and SEM Research Markets

2.6.3 Electron Microscope TEM and SEM Life Sciences Market Shares

2.6.4 Electron Microscope TEM and SEM Life Sciences Market Forecasts

2.6.5 Nanoparticles for Drug Delivery

2.6.6 Electronics Electron Microscope TEM and SEM Market Shares

2.6.7 Electron Microscope TEM and SEM Electronics Market Forecasts

2.6.8 Electron Microscope SEM and TEM Industry Market Shares

2.6.9 Electron Microscope SEM and TEM Industry Market Forecasts

2.7 Optical Microscopes Market Shares

2.7.1 Olympus Group

2.7.2 Nikon Sales Strength

2.7.3 Nikon Biological Microscopes Coolscope II

2.7.4 Nikon Inverted Microscopes (For Research) Eclipse Ti-E

2.7.5 Danaher / Leica Microsystems

2.7.6 Leica M80 Stereomicroscope

2.7.7 Carl Zeiss

2.8 Optical Microscopes Market Forecasts

2.8.1 Worldwide Optical Research Microscope Shipments, Market Shares

2.8.2 Olympus SZX Research Stereomicroscope System

2.8.3 Worldwide Optical Research Microscope Shipments, Market Forecasts

2.8.4 Worldwide Bio-Med And Life Science Optical Microscope Market Shares

2.8.5 Worldwide Bio-Med And Life Science Optical Microscope Market Forecasts

2.8.1 Worldwide Optical Clinical and Surgical Microscope Market Shares

2.8.1 Worldwide Optical Clinical and Surgical Microscope Market Forecasts

2.8.1 Worldwide Optical Industrial and Semiconductor Microscope Market Shares

2.8.1 Nikon Advanced Integration With Peripherals Via Intelligent Software

2.8.2 Nikon Motorized Laser TIRF Illumination Unit

2.8.3 Nikon ECLIPSE L300D Episcopic Illumination Type

2.8.4 Worldwide Optical Industrial and Semiconductor Microscope Market Forecasts

2.8.5 Carl Zeiss

2.8.6 Olympus Materials Research Imaging Solutions

2.9 Customized Focused Ion And Electron Beam Columns Microscopes

2.9.1 Orsay Physics

2.10 Lensless Microscope Technology Electron Microscopy And Optical Microscopy Markets

2.10.1 Phase Focus

2.11 Microscope Market Regional Segments

2.11.1 Carl Zeiss Revenue By Region

2.11.2 Carl Zeiss Regional Revenue Segments

2.11.3 FEI Revenue by Region

2.11.4 Agilent Revenue by Region

3. MICROSCOPE PRODUCT DESCRIPTION

3.1 Olympus

3.1.1 Olympus SZX Research Stereomicroscope System

3.1.2 Olympus Integration of Apochromatic System

3.1.3 Olympus Vertical Observation

3.1.4 Olympus Multiphoton Microscope

3.1.5 Olympus Confocal Microscope

3.1.6 Olympus Confocal Microscope Laser Monitoring Function

3.1.7 Olympus Photo Stimulation

3.1.8 Olympus Unmixing

3.1.9 Olympus Colocalization

3.1.10 Olympus Industrial Micro-Imaging Segments

3.1.11 Olympus Materials Research Imaging Solutions

3.1.12 Olympus Ceramics

3.1.13 Olympus Plastics Microscopes

3.1.14 Olympus Materials Forming

3.1.15 Olympus Semiconductor Imaging Solutions

3.1.16 Olympus - Bacus Laboratories - Virtual Microscopy

3.2 Nikon

3.2.1 Nikon ECLIPSE L300D Episcopic

3.2.2 Nikon CFI60

3.2.3 Nikon Biological Microscopes COOLSCOPE II

3.2.4 Nikon Low Magnification Model

3.2.5 Nikon ECLIPSE E200POL

3.2.6 Nikon Inverted Microscopes (For Research) Eclipse Ti-E

3.2.7 Nikon High-Speed Motorized Control And Acquisition

3.2.8 Nikon Advanced Integration With Peripherals Via Intelligent Software

3.2.9 Nikon Motorized Laser TIRF Illumination Unit

3.2.10 Nikon Photo Activation Illumination Unit

3.2.11 Nikon Multiport Design With A Maximum Of Five Imaging Ports

3.2.12 Nikon Industrial Microscopes

3.2.13 Nikon ECLIPSE L300D Episcopic Illumination Type

3.2.14 Nikon Stereoscopic Microscopes

3.2.15 Nikon Semiconductor Inspection Equipment

3.2.16 Nikon Inspection Equipment

3.3 Carl Zeiss

3.3.1 Carl Zeiss Axio

3.3.2 Zeiss Stereo Microscopes

3.3.3 Zeiss SteREO Discovery.V20

3.3.4 Zeiss SteREO Discovery Final Assembly Of The Stereomicroscope

3.3.5 Zeiss SteREO Discovery

3.3.6 Zeiss AxioVision Microscope Software

3.3.7 Carl Zeiss SteREO Discovery.V20 Provides Depth Perception

3.3.8 Carl Zeiss SteREO Discovery.V12

3.3.9 Zeiss Confocal Microscopes

3.3.10 Zeiss Confocal Systems Axio CSM 700

3.3.11 Carl Zeiss Axio CSM 700 Reliably Assesses Surface Quality

3.3.12 Carl Zeiss Topography for LSM

3.3.13 Carl Zeiss ORION™ Helium Ion Microscope

3.4 Leica

3.4.1 Leica M80 Stereomicroscope

3.4.2 Leica M400 E Surgical Microscope

3.4.3 Detailed Description

3.4.4 Leica M80

3.4.5 Leica TCS SP5 X Supercontinuum Confocal Microscope

3.5 Unitron

3.6 Meiji Techno

3.7 Motic 3-126

3.8 American Optical

3.9 Lumenera

3.10 Diagnostic Instruments

3.11 Meiji Techno Microscopes

3.11.1 Meiji MT4000 Series Laboratory and Student Compound Microscopes in Transmitted Light Brightfield and Phase Contrast.

3.11.2 Meiji MT4200 Binocular & MT4300 Trinocular

3.11.3 Meiji MT5000 Series Laboratory Compound Microscopes in Transmitted Light Brightfield and Phase Contrast

3.11.4 Meiji IM7000 Series and Meiji MT9000 Series

3.11.5 Meiji RZ Research Zoom Stereomicroscope:

3.11.6 Meiji EMZ Zoom Stereomicroscopes:

3.12 FEI Electron Microscopes SEM and TEM

3.12.1 FEI Phenom Applications

3.12.2 Metallurgical Applications Using The FEI Phenom

3.12.3 Forensic Applications of FEI Scanning Electron Microscopy

3.12.4 FEI Micron Scale Insect Anatomy

3.12.5 FEI Phenom Use for Pharmaceutical Particle Inspection

3.12.6 FEI Topography Imaging With Phenom

3.12.7 FEI Product Offerings

3.12.8 FEI SEM Transition in Imaging

3.12.9 FEI TEM Product Positioning

3.13 Hitachi

3.13.1 Hitachi S-5500 In-lens FE-SEM

3.14 Jeol Scanning Electron Microscopes

3.14.1 Jeol JXA-8500F Electron Probe Microanalyzer (EPMA)

3.14.2 JEOL Electron Microscope Semiconductor Equipment

3.15 Alicona Imaging

3.15.1 Alicona Imaging InfiniteFocus

3.15.2 Alicona Imaging InfiniteFocusRobot

3.15.3 Alicona Imaging InfiniteFocus Real 3D

3.15.4 Alicona Imaging InfiniteFocus Inline

3.15.5 Alicona Imaging EdgeMaster

3.15.6 Alicona Imaging MeX

3.16 Anderson Materials Evaluation EDS, XRF, and FTIR

3.16.1 Anderson Materials XPS Surface Analysis Technique

3.16.2 Anderson Materials XPS System Capabilities

3.16.3 Anderson Materials XPS Applications

3.16.4 Anderson Materials ESCA Surface Analysis Applications

3.16.5 Anderson Materials X-ray Photoelectron Spectroscopy

3.17 Westover Scientific Telecommunications Fiber Optic Network Probe

3.18 AIST-NT Co

3.18.1 AIST-NT Co Products

3.19 Angstrom - Advanced

3.20 Angstrom Advanced

3.21 Agilent Technologies Atomic Force Microscopes

3.21.1 Agilent Technologies In Particle Analysis

3.21.2 Agilent Particle Analysis Target Markets

3.21.3 Agilent Inks And Pigments

3.21.4 Agilent Specialty Chemicals

3.22 Veeco

3.23 Asylum Research

3.23.1 Asylum Cypher AFM Features

3.23.2 Asylum Nanoindenting

3.23.3 Asylum Research Atomic Force Microscope (AFM)

3.23.4 Asylum Research Atomic Force Microscope Technical Innovations

3.24 JPK Instruments

3.25 Nanosurf FlexAFM easyScan 2

3.26 Bruker AXS

3.27 Nanonics

3.27.1 Nanonics Confocal Microscope

3.27.2 Nanonics Confocal Microscope

3.27.3 Nanonics Dual Microscope

3.27.4 Nanonics Dual Microscope Combined Upright and Inverted Systems

3.27.5 Nanonics SPM & NSOM Systems

3.27.6 Nanonics Transparent Correlation of Raman and SPM Imaging.

3.27.7 Nanonics Parallel Imaging

3.27.8 Nanonics Raman Mapping with Z-Control

3.27.9 Nanonics Examples of the Power of Integrated Raman/AFM

3.27.10 Nanoindentation Correlated with Material Properties

3.27.11 Local Stress of MEMs Devices

3.27.12 Intermittent Contact Mode in Liquids

3.28 Nanotec Electrónica

3.28.1 Nanotec Products

3.29 Cervantes AFM System

3.30 Dulcinea Control System

3.31 Omicron Multiprobe MBE and S System For Thin Film Deposition Analysis

3.31.1 Omicron Multiprobe MXPS Thin Film Studies With Pulsed Laser Deposition (PLD) System

3.31.2 Omicron Multiscan LAB:

3.31.3 Omicron Customized Solution for 2.5 - 350 K STM Operation in 3D Magnetic Fields

3.32 Veeco

3.32.1 Veeco BioScope II Atomic Force Microscope - Combining atomic force And Optical Microscopy

3.32.2 Veeco BioScope SZ Atomic Force Microscope Designed For Life Sciences Research

3.32.3 Veeco Caliber Atomic Force Microscope AFM with Research-Quality Results

3.32.4 Veeco Dimension 3100 Scanning Probe Microscope - Superior research versatility

3.32.5 Veeco Dimension 5000 Scanning Probe Microscope Large-Sample Metrology And Imaging

3.32.6 Veeco Dimension V Scanning Probe Microscope - Superior High-Resolution Research Performance And Versatility

3.32.7 Veeco Electrochemical SPM Real-Time Electrochemical Processes In-Situ

3.32.8 Veeco EnviroScope Atomic Force Microscope - Combined AFM Imaging With Sample Environmental Control

3.32.9 Veeco Innova Scanning Probe Microscope Low Noise, High Resolution AFM

3.32.10 Veeco MultiMode V Scanning Probe Microscope High Resolution SPM

3.32.11 NanoMan VS Scanning Probe Microscope Enabling Advanced Nanoscale Surface Manipulation

3.32.12 Veeco Scanning Probe Microscope Force Spectroscopy Research

3.33 Agilent

3.34 Orsay Physics S.A.

3.34.1 Orsay Physics S.A. COBRA-FIB Column

3.35 Seiko

3.35.1 Seiko SUPRA 55VP Versatile High Performance VP SEM

3.35.2 Carl Zeiss NVision 40 FIB-SEM

3.35.3 Carl Zeiss NVision DES100 1540XB CrossBeam/

4. MICROSCOPE TECHNOLOGY

4.1 IBM Microscope 100 Million Times Finer Resolution Than Current MRI

4.1.1 IBM Research

4.2 Technological Trends in the Microscopy Business

4.3 Industry Overview

4.3.1 Key Trends in the Laboratory Equipment Market

4.3.2 Semiconductor Industry

4.4 Surface Science Technologies

4.4.1 Surface Analyzers

5. MICROSCOPE COMPANY PROFILES

5.1 Alicona Imaging

5.2 Aligent

5.2.1 Agilent Technologies Inc. (NYSE: A) High-Precision Atomic Force Microscopes (AFM)

5.2.2 Agilent Technologies Atomic Force Microscopes

5.2.3 Agilent Buys Nano Instruments

5.2.4 Agilent Technologies Atomic Force Microscopes Consumables

5.2.5 Agilent Gold Mica Substrates

5.2.6 Agilent Hydrogen Flame Annealing

5.2.7 Agilent Net Revenue Fiscal Year 2008

5.2.8 Agilent Electronic and Communications Measurement

5.2.9 Agilent Bio-Analytical Measurement

5.2.10 Agilent Laboratories

5.2.11 Agilent Technologies Fourth Quarter 2008 Revenue

5.2.12 Agilent Electronic Measurement

5.2.13 Agilent Technologies Revenue

5.3 Angstrom Advanced

5.4 Asylum Research

5.5 Bausch and Lomb

5.6 Bruker

5.6.1 Bruker Acquires S.I.S. Surface Imaging System In the AFM Market

5.7 Carl Zeiss

5.7.1 Carl Zeiss Regional Revenue Segments

5.7.2 Carl Zeiss Foundation Organizational Structure

5.7.3 Carl Zeiss Reorganization of Business Units

5.7.4 Carl Zeiss AxioVision Physiology Microscope System

5.7.5 Carl Zeiss Meditec

5.7.6 Carl Zeiss Revenue By Strategic Business Segment

5.7.7 Carl Zeiss Revenue By Region

5.7.8 Zeiss Outlook

5.7.9 Zeiss Clinical Diagnostics ACIS III System Developed by Clarient

5.8 Danaher Corporation

5.8.1 Danaher Revenue For Fourth Quarter And Full Year 2008

5.8.2 Danaher Operating Segments

5.8.3 Danaher Third Quarter Revenue

5.8.4 Danaher / Leica Brand

5.8.5 Danaher / Leica Microsystems

5.8.6 Leica Microsystems’ Life Science Division

5.8.7 Leica Professional Instrumentation

5.8.8 Leica Industrial Technologies

5.8.9 Danaher Tools & Components

5.8.10 Leica Microsystems Acquires Surgipath Medical Industries, Inc.

5.8.11 Leica Microsystems’ Life Science Division

5.8.12 Danaher Leica Microsystems’ Industry Division

5.8.13 Danaher Leica Microsystems’ Biosystems Division

5.8.14 Danaher Leica Microsystems’ Surgical Division

5.8.15 Danaher / Leica MM AF Imaging Systems and MetaMorph Software

5.9 FEI

5.9.1 FEI Acquires Intellection Holdings

5.9.2 FEI Suppliers

5.9.3 FEI Technologies And Applications

5.9.4 FEI Worldwide Presence

5.9.5 Japan's Leading National Institute Orders Powerful Microscope from FEI

5.9.6 FEI's Titan Krios TEM Selected by Leading Life

Science Research Centers in Asia

5.9.7 King Abdullah University of Science and Technology and FEI Company Team to Create Major Nanoscience Facility

5.9.8 FEI Revenue

5.9.9 FEI Strategic Positioning

5.9.10 FEI Life Sciences Instrument Positioning

5.9.11 FEI Three major markets - Research & Industry, Electronics and Life Sciences Segment Information

5.9.12 FEI Electronics Segments

5.9.13 FEI Research and Industry

5.9.14 FEI Life Sciences

5.9.15 FEI Service and Components

5.9.16 FEI Electronics Market

5.9.17 FEI Research And Industry Market

5.9.18 FEI Life Sciences

5.9.19 FEI Order Cancellations

5.9.20 FEI Sales by Geographic Region

5.9.21 FEI North America

5.9.22 FEI Europe

5.9.23 FEI Asia-Pacific Region

5.9.24 FEI SEM Phenom Scope

5.9.25 FEI Fits in the Semiconductor Microscope Equipment Supply Chain

5.9.26 FEI Leader in Tools for Nanotechnology

5.9.27 FEI Titan Electron Microscope (TEM) Designed By Philips Design

5.10 Hitachi

5.11 Jeol

5.11.1 Jeol Electron Optics

5.11.2 Jeol Analytical Instruments

5.11.3 Jeol Semiconductor Equipment

5.11.4 Jeol Thin Film Coating Systems

5.11.5 Jeol Medical Equipment

5.12 JPK Instruments

5.12.1 JPK Instruments Business units

5.12.2 Molecular Analytics Division

5.13 Kaust

5.14 Labomed

5.15 Motic

5.15.1 Motic Contract With Carl Zeiss

5.16 Nanotec Electronica / Nanonics

5.17 Nanosurf

5.17.1 Nanosurf Integrated Microscopy

5.17.2 Nanosurf Technology

5.18 NIKON

5.18.1 Nikon Revenue

5.18.2 Nikon Instruments Business

5.18.3 Nikon Geographical Segments

5.18.4 Nikon Instrument Product Line

5.18.5 Nikon Stereoscopic Microscopes

5.18.6 Nikon Cameras for Microscopy

5.18.7 Nikon Bioscience Field Market Environment and Business Trends

5.18.8 Nikon Business Strategy

5.18.9 Nikon Instruments and Biosciences Business

5.19 Olympus

5.19.1 Olympus Microscopes For Industrial Applications

5.19.2 Olympus Micro-Imaging

5.19.3 Olympus Centre Strengthens R&D In Lab Equipment

5.20 Omicron

5.20.1 Omicron High-Performance STM Operation

5.20.2 Omicron Customized Solution

5.21 Orsay Physics S.A.

5.22 Phase Focus

5.22.1 Phase Focus 'Lenless' Optical Microscope

5.22.2 Phase Focus / Fusion IP £250k Funding

5.23 Raith

5.23.1 Raith Secure Customers Investments

5.24 Seiko Instruments Inc. (SII)

5.24.1 Seiko Holdings

5.24.2 Seiko Watch Corporation

5.24.3 Seiko Clock

5.24.4 Seiko Precision

5.24.5 Seiko Instruments (SII)

5.24.6 Seiko Epson

5.25 Thermo Fisher Scientific

5.26 Veecro

5.26.1 Veeco Third Quarter and Nine Month 2008 Revenue

5.27 Westover Scientific

5.28 Selected Microscopy Vendors

5.28.1 Atomic Force Microscope Manufacturers

5.28.2 Grandeye

5.28.3 BioTek

5.28.4 Avo Photonics

List of Tables and Figures

Table ES-1

Microscope Market Driving Forces

Table ES-1 (Continued)

Microscope Market Driving Forces

Table ES-2

Technology Impact on Microscope Market Driving Forces

Table ES-3

Worldwide Microscope

Shipments Market Shares, Dollars, 2008

Figure ES-4

Worldwide Optical and Electron Microscope Market

Forecasts, Dollars, 2009-2015

Figure ES-5

FEI From Wafer to Atomic Resolution

Figure ES-6

FEI Industry Transition in Imaging

Figure 1-1

Platinum Electrode Measuring One Hundredth

Of A Nanometer Deposited On Pyramid Shaped

AFM Tip Via Focused Ion Beam (Fib) Deposition

Table 1-2

Emerging Topics In Microscopy And Microanalysis

Table 1-3

Commercial Microscope Modules

Table 1-4

Microscope Market Segments

Table 1-5

Stereo Microscope Features

Table 1-5 (Continued)

Stereo Microscope Features

Table 2-1

Microscope Market Driving Forces

Table 2-1 (Continued)

Microscope Market Driving Forces

Table 2-2

Technology Impact on Microscope Market Driving Forces

Table 2-3

Worldwide Microscope

Shipments Market Shares, Dollars, 2008

Table 2-4

Worldwide Microscope

Shipments Market Shares, Dollars, 2008

Figure 2-5

Worldwide Optical and Electron Microscope

Market Forecasts, Dollars, 2009-2015

Table 2-6

Worldwide Total Optical and Electron Microscope

Market Forecasts, Dollars, 2009-2015

Figure 2-7

Worldwide Optical and Electron Microscope

Market Segments, 2008

Figure 2-8

Worldwide Optical and Electron Microscope Market Segments, 2015

Table 2-9

Worldwide Optical and Electron Microscope

Market Segments, Dollars, 2009-2015

Figure 2-10

FEI Magellan Nanoscale Characterization

Down To The Level of Atoms

Figure 2-11

Improvements in Visualization from SEM to TEM

Figure 2-12

FEI Titan Nanoscale Visualization Down To The Level Of Atoms

Table 2-13

Comparison of AFM, TEM, SEM, and Optical

Microscopy Techniques

Table 2-14

Worldwide TEM and SEM Electron Microscope Shipments

Market Shares, Dollars, 2008

Table 2-15

Worldwide TEM and SEM Electron Microscope Shipments

Market Shares, Dollars, 2008

Table 2-16

Worldwide Electron Microscope

Market Forecasts, Dollars, 2009-2015

Table 2-17

Worldwide Electron Microscope

Market Forecasts, Dollars, 2009-2015

Figure 2-18

Worldwide TEM and SEM Electron Microscope

Shipments, Research, Bio-Med and Life Sciences,

Clinical and Surgical, Industrial, Mining and Materials,

Electronics and Semiconductor, and Ion Beam

Market Forecasts, Units and Dollars, 2009-2015

Figure 2-19

Worldwide Research TEM and SEM Electron Microscope

Shipments Market Shares, Dollars, 2008

Table 2-20

Worldwide Research TEM and SEM Electron Microscope

Shipments Market Shares, Dollars, 2008

Table 2-21

JEOL Electron Microscope Products

Table 2-22

JEOL Analytical Instrument Products

Figure 2-23

Carl Zeiss ORION™ Helium Ion Microscope

Figure 2-24

Worldwide Research TEM and SEM

Electron Microscope Market Forecasts, Dollars, 2009-2015

Figure 2-25

Nanotechnology Funding of National Programs

Table 2-26

FEI Electron Microscope Research Positioning

Table 2-27

Worldwide Research TEM and SEM Electron

Microscope Shipments Market Forecasts,

Units and Dollars, 2009-2015

Table 2-28

Electron Microscope TEM and SEM Research

Segment Growth Drivers

Table 2-29

Worldwide Bio-Med and Life Science Shipments

TEM and SEM Electron Microscope Market Shares,

Dollars, 2008

Table 2-30

Worldwide Bio-Med and Life Science Shipments

TEM and SEM Electron Microscope Market Shares, Dollars, 2008

Figure 2-31

Worldwide Bio-Med and Life Science TEM and SEM

Electron Microscope Market Forecasts, Dollars, 2009-2015

Figure 2-32

Worldwide Bio-Med and Life Science TEM and SEM

Electron Microscope Market Forecasts, Dollars, 2009-2015

Table 2-33

TEM and SEM Life Sciences Market Growth Factors

Table 2-33 (Continued)

TEM and SEM Life Sciences Market Growth Factors

Figure 2-34

Life Sciences Market Growth

Table 2-35

FEI Solutions For Structural Biology

Table 2-36

University and Government Lab Life Science Applications

Figure 2-37

Nanoparticles for Drug Delivery

Table 2-38

Nanotechnology Life Sciences Market Growth Factors

Table 2-39

Worldwide Electronics and Semiconductor TEM and SEM

Electron Microscope Shipments Market Shares, Dollars, 2008

Table 2-40

Worldwide Electronics and Semiconductor TEM and SEM

Electron Microscope Shipments Market Shares, Dollars, 2008

Figure 2-41

Worldwide Electronics TEM and SEM

Electron Microscope Market Forecasts, Dollars, 2009-2015

Table 2-42

Worldwide Electronics and Semiconductor TEM and

SEM Electron Microscope Shipments

Market Forecasts, Units and Dollars, 2009-2015

Table 2-43

Electron Microscope Semiconductor Equipment Products

Table 2-44

Electron Microscope TEM and SEM Electronics

Market Growth Drivers

Table 2-45

Electron Microscope TEM and SEM Electronics Market Tactics:

Table 2-46

Worldwide Industrial Mining and Materials TEM and SEM

Electron Microscope Shipments Market Shares, Dollars, 2008

Table 2-47

Worldwide Industrial Mining and Materials TEM and SEM

Electron Microscope Shipments Market Shares, Dollars, 2008

Table 2-48

Worldwide Industrial, Mining and Materials TEM and

SEM Electron Microscope Shipments

Market Forecasts, Units and Dollars, 2009-2015

Table 2-49

Worldwide Industrial, Mining and Materials TEM and

SEM Electron Microscope Shipments

Market Forecasts, Units and Dollars, 2009-2015

Table 2-50

Thin Film Coating System Products

Table 2-51

Worldwide Optical Microscopes Market Shares, Dollars, 2008

Table 2-52

Worldwide Optical Microscope Shipments

Market Shares, Dollars, 2008

Figure 2-53

Worldwide Optical Microscope Market Forecasts,

Dollars, 2009-2015

Figure 2-54

Worldwide Optical Microscope Market Forecasts,

Dollars, 2009-2015

Figure 2-55

Worldwide Optical Microscope Shipments, Research,

Bio-Med and Life Sciences, Clinical and Surgical,

Industrial and Semiconductor, Market Forecasts,

Units and Dollars, 2009-2015

Figure 2-56

Worldwide Optical Research Microscope Shipments,

Market Shares, Dollars, 2008

Figure 2-57

Worldwide Optical Research Microscope Shipments,

Market Shares, Dollars, 2008

Figure 2-57

Worldwide Optical Research Microscope Market

Forecasts, Dollars, 2009-2015

Figure 2-58

Worldwide Bio-Med and Life Science Optical

Microscope Shipments, Market Shares, Dollars, 2008

Figure 2-59

Worldwide Bio-Med and Life Science Optical

Microscope Shipments, Market Shares, Dollars, 2008

Figure 2-60

Worldwide Bio-Med And Life Science Optical Microscope

Forecasts, Dollars, 2009-2015

Figure 2-61

Worldwide Optical Clinical and Surgical Microscope Shipments

Market Shares, Dollars, 2008

Table 2-62

Worldwide Optical Clinical and Surgical Microscope Shipments

Market Shares, Dollars, 2008

Figure 2-61

Worldwide Optical Clinical and Surgical Microscope Shipments

Market Forecasts, Dollars, 2009-2015

Figure 2-62

Worldwide Optical Industrial and Semiconductor

Microscope Shipments Market Shares, Dollars, 2008

Figure 2-63

Worldwide Optical Industrial and Semiconductor

Microscope Shipments Market Shares, Dollars, 2008

Figure 2-64

Worldwide Optical Industrial and Semiconductor

Microscope Market Forecasts, Dollars, 2009-2015

Table 2-65

Customized Focused Ion And Electron Beam Column

Microscope Market Competitive Factors

Figure 2-66

Worldwide Customized Focused Ion and Electron Beam

Columns

Microscope Shipments Market Shares, Dollars, 2008

Table 2-67

Worldwide Customized Focused Ion and Electron Beam

Columns

Microscope Shipments Market Shares, Dollars, 2008

Figure 2-68

Worldwide Focused Ion Beam and Electron Beam Columns

Electron Microscope Market Forecasts, Dollars, 2009-2015

Figure 2-69

Worldwide Focused Ion Beam and Electron Beam Columns

SEM and TEM Electron Microscope Market Forecasts,

Dollars, 2009-2015

Table 2-70

Regional Microscope Shipment Analysis

Market Shares, Dollars, 2008

Table 2-71

Regional Microscope Shipment Analysis

Market Shares, Dollars, 2008

Figure 5-72

FEI Growth and Regional Diversity

Table 2-73

FEI Nanotechnology Research Center Penetration

Figure 3-1

Olympus SZX16 Advanced Research Microscope

Table 3-2

Olympus SZX16 Research Microscope Benefits

Table 3-2 (Continued)

Olympus SZX16 Research Microscope Benefits

Table 3-3

Olympus SDF Objective Lenses Features

Figure 3-4

Olympus Multiphoton Microscope

Table 3-5

Olympus FV1000MPE TWIN Features

Table 3-6

Olympus Confocal Microscope Benefits

Table 3-7

Olympus Confocal Microscope Evolved Laser Light Stimulation

Table 3-8

Olympus Confocal Microscope Evolved Basic Performance

Table 3-9

Olympus Confocal Microscope Quantification

Table 3-10

Olympus Confocal Microscope High Sensitivity

Figure 3-11

Olympus Confocal Microscope

Table 3-12

Olympus Industrial Micro-Imaging Segments

Figure 3-13

Olympus Semiconductor Imaging Solutions

Table 3-14

Olympus Virtual Microscopy Applications

Table 3-15

Nikon CFI60 Features

Figure 3-16

Nikon CFI60

Figure 3-17

Nikon COOLSCOPE2 Main Screen And Controller

Table 3-18

Nikon Low Magnification Features

Table 3-19

Nikon Low Magnification Microscope Features

Table 3-19 (Continued)

Nikon Low Magnification Microscope Features

Figure 3-20

Nikon ECLIPSE E200POL

Figure 3-21

Nikon Inverted Microscopes For Research ECLIPSE Ti-E

Table 3-22

ECLIPSE L300D Episcopic Illumination Type

Figure 3-23

Nikon ECLIPSE L300D Episcopic Illumination Type

Table 3-24

Selected Nikon Industrial Microscopes and Accessories and Other

Table 3-25

Nikon Stereoscopic Zoom Microscope SMZ1500 Features

Figure 3-26

SMZ1500 With Epi-Fluorescence Attachment

Table 3-27

Stereoscopic Zoom Microscope Products

Table 3-28

Nikon Wafer Edge Bevel Inspection System

WES-3000 Major Features

Figure 3-29

Nikon Wafer Edge Bevel Inspection System WES-3000

Table 3-30

Nikon Wafer Edge Bevel Inspection System

Applications and Functions

Table 3-31

Nikon Wafer Edge Bevel Inspection System Products

Table 3-32

Nikon Inspection Equipment

Figure 3-33

Zeiss Axio

Figure 3-34

Zeiss Stereo Microscope

Figure 3-35

Zeiss SteREO Lumar

Table 3-36

Zeiss SteREO Discovery.V20

Table 3-37

Zeiss SteREO Discovery.V20 Features

Table 3-38

Zeiss SteREO Discovery.V20 Microscopic Sharper

Images Benefits

Table 3-39

Zeiss SteREO Discovery Stereomicroscope

Final Assembly Process

Figure 3-40

Zeiss Final Assembly Of The Stereomicroscope

Figure 3-41

Zeiss Benefits of Sharper Image From Computer Based Alignment

Figure 3-42

Carl Zeiss SteREO Discovery.V20 Image Quality

Table 3-43

Carl Zeiss Stereomicroscopy Benefits

Table 3-44

Carl Zeiss SteREO Discovery.V12 Stereomicroscopy Applications

Figure 3-45

Axio Observer

Table 3-46

Zeiss Live Cell Imaging under Physiological Conditions

Table 3-47

Zeiss Imaging

Figure 3-48

Zeiss Confocal Microscopes Support Fluorescence

Correlation Spectroscopy To Visualize Dynamics At

The Molecular Level

Figure 3-49

Carl Zeiss Axio CSM 700

Figure 3-50

Carl Zeiss LSM 700 Confocal Laser Scanning Microscope

3D Topography & Fluorescence Measurements

Figure 3-51

Zeiss High-End Confocal Microscope

Figure 3-52

Carl Zeiss LSM 5 Macros

Figure 3-53

Carl Zeiss AxioVision Physiology Microscope System

Figure 3-54

Carl Zeiss ORION™ Helium Ion Microscope

Table 3-55

Leica Microscope Product Positioning

Figure 3-56

Leica M80 stereomicroscope

Table 3-57

Leica M400 E Surgical Microscope Key Features

Figure 3-58

Leica M125 Trinocular Zoom Stereomicroscope

with Ergonomic Tilting

Figure 3-59

Leica Transmitted Light Darkfield Example

Table 3-60

Leica Microsystems GmbH Wetzlar, Germany

Table 3-61

Leica Optical Microscope Product Set

Figure 3-62

Leica M205 A Stereomicroscope

Table 3-63

Leica M205 A Key Features

Table 3-64

American Optical Cycloptic Stereomicroscope

Figure 3-65

American Optical Cycloptic Microscope

Table 3-66

Meiji's EMZ Stereomicroscope Models

Figure 3-67

Meiji Microscopes

Table 3-68

Meiji EMZ13TR Trinocular Zoom Stereo

Table 3-69

FEI's Phenom™ Desktop SEM Key Specifications

Figure 3-70

FEI Scanning Microscope

Table 3-71

FEI Phenom Desktop SEM Modules

Figure 3-72

FEI Broad Product Positioning

Figure 3-73

FEI Throughput Solution

Figure 3-74

Microscope Industry Transition in Imaging

Figure 3-75

FEI SEM Magellan Extreme High Resolution

Figure 3-76

FEI Magellan SEM Semi Process Development Application

Figure 3-77

FEI Magellan Nanoscale Characterization

Down To The Level Of Atoms

Figure 3-78

FEI Titan Nanoscale Visualization Down To The Level Of Atoms

Figure 3-79

FEI TEM Titan For Biology

Figure 3-80

FEI Solutions for Cellular Biology: 3D Tomography Software

Figure 3-81

FEI Emerging Solutions for Biology

Figure 3-82

FEI Solutions for Nanoparticles

Table 3-83

Hitachi Electron Microscopes

Figure 3-84

Hitachi H-9500 300kV TEM

Table 3-85

Hitachi S-5500 In-lens FE-SEM Features

Table 3-86

Hitachi S-5500 In-lens FE-SEM Product Number:S-5500 Features

Figure 3-87

Hitachi S-5500 In-lens FE-SEM

Figure 3-88

Hitachi TEM

Table 3-89

Hitachi FIB + SEM TM-1000 Tabletop Microscope Benefits

Table 3-90

Hitachi TEM System Specifications

Figure 3-91

Jeol Scanning Electron Microscope

Table 3-92

Jeol JXA-8500FThe Electron Microscope Benefits

Table 3-93

Jeol Electron Microscope Semiconductor Products

Figure 3-94

Alicona Imaging InfiniteFocus Robot

Table 3-95

Anderson Materials XPS Surface Analysis Technique

Table 3-96

Anderson Materials ESCA Samples and Materials

Figure 3-97

Westover Scientific Telecommunications Fiber Optic

Network Probe Microscope

Figure 3-98

Westover Scientific FiberChek2 Probe

Figure 3-99

Westover Scientific Fiber Probes

Table 3-100

AIST-NT Co Products

Figure 3-101

AIST-NT Images

Figure 3-102

AIST-NT Piezo Response Imaging

Figure 3-103

AIST-NT Topography image of PZT

Figure 3-104

AIST-NT Images Piezo response image (normal force).

Left - amplitude. Right - phase.

Figure 3-105

AIST-NT Polymer Images

Figure 3-106

AIST-NT Images

Figure 3-107

AIST-NT Images Nanolithography

Figure 3-108

AIST-NT Images Diamond Materials

Figure 3-109

AIST-NT MaterialsImages Kelvin Probe Microscopy image

Figure 3-110

Angstrom Advanced Atomic Force

Microscope and Scanning Probe Microscope

Figure 3-111

Angstrom Advanced Ellipsometer

Table 3-112

Agilent Atomic Force Microscopes industry segments

Table 3-113

Agilent Atomic Force Microscopes Applications

Figure 3-114

Veeco AFMs for Research

Figure 3-115

Veeco AFMs

Figure 3-116

Asylum’s MFP-3D AFM

Table 3-117

Asylum Cypher AFM Features

Figure 3-118

Asylum Research Closed loop STM Showing

Graphite Atoms, 6nm Scan

Figure 3-119

Asylum Research Automated Laser Alignment

Figure 3-120

Asylum Research Loop Image Of Domains Of

Surfactant Hemi-Micelles Surrounding A Defect On

Graphite, 200nm Scan

Figure 3-121

Asylum Research. Closed Loop Image

Of Extracellular Face Of Bacteriorhodopsin In Buffer

Table 3-122

Asylum Research Modules

Table 3-123

Asylum Types of Microscopy

Table 3-124

Asylum Cypher AFM

Table 3-125

Asylum Specifications

Table 3-126

Asylum Scanner Modules

Table 3-127

Asylum Standard View Module Specifications

Table 3-128

Asylum Research Atomic Force Microscope

Technical Innovation

Figure 3-129

Asylum Research Atomic Force Microscope

Figure 3-130

Asylum Research Atomic Force Microscope MFP-3D Head

Figure 3-131

Asylum Research Atomic Force Microscope

Nano-Positioning System

Figure 3-132

Asylum Research Atomic Force Microscope

MFP-3D XY Scanner

Figure 3-133

Asylum Research Atomic Force Microscope MFP-3D XY

Figure 3-134

Asylm Image Of A Hard Disk, 20μm scan Science Applications

Figure 3-135

Lithography Nanografting of thiols on a Au(111) surface.

1.5μm Scan

Table 3-136

JPK Instruments Solutions

Table 3-137

JPK Instruments Applications

Table 3-138

JPK Instruments Major AFM Modes

Figure 2-139

Nanosurf easyScan 2Product Lines

Figure 3-140

Nanosurf Mobile S Provides Portable, All-in-One AFM System

Figure 3-141

Nanosurf Nanite

Table 3-142

Nanosurf Nanite Features

Figure 3-143

Bruker AXS

Figure 3-144

Nanonics Confocal Microscope

Table 3-145

Nanonics Confocal Microscope Features

Table 3-146

Nanonics Dual (upright/inverted) Microscope

Table 3-147

Nanonics Dual Microscope

Figure 3-148

Nanonics Dual Microscope Combined Upright and Inverted Systems

Figure 3-149

Nanonics Dual Microscope Combined Upright and Inverted Systems

Figure 3-150

Nanonics Systems Combining AFM and Raman

Figure 3-151

Nanonics AFM without Optical Obstruction

Figure 3-152

Nanonics Parallel Imaging of a Silicon Semiconductor

Table 3-153

Nanonics Difference Between Raman Mapping With And

Without Z-Control Vibration Mode of Diamond at 1334cm-1

Figure 3-154

Raman Shift as a Function of Local Stress Location

Figure 3-155

Omicron Multiprobe MXPS System For Thin Film Studies

Figure 3-156

Omicron Multiscan LAB Combined With a

Multiprobe MXPS System

Figure 3-157

Omicron Customized Solution for 2.5 -

350 K STM Operation in 3D Magnetic Fields

Figure 3-158

Omicron Customized Microscope

Table 3-159

Veeco BioScope II Atomic Force Microscope Product Description

Table 3-160

Veeco BioScope SZ Atomic Force Microscope Product Features:

Table 3-161

Veeco Caliber Atomic Force Microscope Product Features:

Table 3-162

Veeco Dimension 3100 Scanning Probe Microscope Product Features:

Table 3-163

Veeco Dimension 5000 Scanning Probe Microscope

Product Features:

Table 3-164

Veeco Dimension V Scanning Probe Microscope Product Features:

Table 3-165

Veeco Electrochemical SPM Product Features:

Table 3-166

Veeco EnviroScope Atomic Force Microscope

Product Features & Benefits:

Table 3-167

Veeco Innova Scanning Probe Microscope Product Features:

Table 3-168

Veeco MultiMode V Scanning Probe Microscope Product Features:

Table 3-169

NanoMan VS Scanning Probe Microscope Product Features:

Table 3-170

Veeco Scanning Probe Microscope Product Features & Benefits:

Figure 3-171

Agilent 5500 AFM (N9410S)

Figure 3-172

Agilent 5500 AFM Imaging Modes

Figure 3-173

Agilent Photodetector Atomic Visualization

Figure 3-174

Agilent Region Where The Tip Approaches The Surface

Figure 3-175

Orsay Physics S.A. COBRA-FIB Column

Table 3-176

Seiko ULTRA 55 Transmission Electron Microscope Features

Figure 3-177

Zeiss NVision 40 FIB-SEM NVision 40 FIB-SEM Cross

Beam System

Table 3-178

Carl Zeiss NVision 40 FIB-SEM Features

Table 4-1

Computerization Of Microscopic Manufacturing Procedure Benefits

Table 5-1

Alicona Microscope Applications Research And Development

Table 5-2

Agilent Electronic And Bio-Analytical Measurement Positioning

Table 5-3

Agilent Nanotechnology Microscope Instruments

Table 5-3 (Continued)

Agilent Nanotechnology Microscope Instruments

Table 5-4

Agilent Nanotechnology Microscope Instruments

Agilent Applications

Table 5-4 (Continued)

Agilent Nanotechnology Microscope Instruments

Agilent Applications

Table 5-4 (Continued)

Agilent Nanotechnology Microscope Instruments

Agilent Applications

Table 5-5

Agilent Imagining Modes

Table 5-6

Agilent Technologies Atomic Force Microscopes Consumables

Figure 5-7

Agilent Revenue by Market Segment Q4 2008

Figure 5-8

Agilent Revenue by Market Segment FY 2008

Figure 5-9

Agilent Revenue by Geographical Region Q4 2008

Figure 5-10

Agilent Revenue by Geographical Region FY 2008

Table 5-11

Agilent Networks Communications Measurement Types

Table 5-12

Agilent General Purpose Test Products

Table 5-13

Agilent Communications Technology Addressed

with Test Equipment

Table 5-14

Agilent Bio-Analytical Measurement Business

Application-Focused Solutions

Table 5-15

Agilent Chemical and Segment Analysis Market Focus

Table 5-16

Agilent Key Product Categories For The

Bio-Analytical Measurements

Table 5-17

Markets In Which Carl Zeiss Participates

Figure 5-18

Carl Zeiss AxioVision Physiology Microscope System

Figure 5-19

Leica Microsystems Latest Products

Table 5-20

Life Science Division Products

Table 5-21

Danaher Leica Microsystems’ Life Science Division Products

Table 5-22

Danaher Leica Microsystems’ Industry Division Products

Table 5-23

Danaher Leica Microsystems’ Biosystems Division Products

Table 5-24

Danaher Leica Microsystems’ Surgical Division Products

Figure 5-25

FEI Growth and Regional Diversity

Table 5-26

FEI Overall Revenue Levels, Electronics vs. Other Levels

Table 5-27

FEI Nanotechnology Research Center Penetration

Figure 5-28

FEI Life Sciences Instrument Landscape

Table 5-29

FEI Strategic Positioning

Table 5-30

FEI Q3 2008 Summary Results

Table 5-31

FEI Broad Product Line That Creates And Measures Nanostructures

Figure 5-32

FEI Product Track

Table 5-33

FEI Titan -World’s Most Powerful Electron Microscope Features

Table 5-34

FEI Imago Scientific Instruments Collaboration

Figure 5-35

FEI Industry Transition in Imaging

Figure 5-36

FEI From Wafer to Atomic Resolution

Figure 5-37

FEI Life Sciences Instrument Landscape

Figure 5-38

FEI Role in Life Sciences

Figure 5-39

FEI Titan Krios and Titan Global Life Sciences Regional Activity

Figure 5-40

FEI Segment Analysis

Table 5-41

Jeol Electron Optic Products

Table 5-42

Jeol Analytical Instruments Products

Table 5-43

Jeol Semiconductor Equipment Products

Table 5-44

Jeol Thin Film Coating System Products

Table 5-45

Jeol Medical Equipment Products

Table 5-46

Jeol Priority Fields Of The Basic Plan For Scientific Technologies

Table 5-47

Selected Jeol Microscope Products

Table 5-48

Motic Products

Figure 5-49

Nikon Segment and Regional Revenue Analysis

Source: Nikon.

Figure 5-50

Nikon Imaging Segment Revenue Analysis

Figure 5-51

Nikon Imaging, Precision Equipment, and

Instruments Segment Revenue Analysis

Table 5-52

Nikon Imaging, Precision Equipment, and

Instruments Segment Revenue Analysis

Figure 5-53

Nikon Regional Segment Revenue Analysis

Table 5-54

Nikon Regional Segment Revenue Analysis

Figure 5-55

Nikon Financial Results by Quarter

Table 5-56

Nikon Financial Results by Quarter

Table 5-57

Nikon Consolidated Financial Results

Table 5-58

Nikon Instrument Product Line

Table 5-59

Nikon Biological Microscopes

Table 5-60

Nikon Industrial Microscopes

Table 5-61

Nikon Stereoscopic Microscope Products

Table 5-62

Nikon Cameras for Microscopy

Table 5-63

Nikon Microscopic Image Recording Equipment

Figure 5-64

Nikon Product Development Strategy

Table 5-65

Nikon Wafer Edge Chips And Damage Microscopes Features

Figure 5-66

Olympus Microscopes

Table 5-67

Orsay Physics S.A. Customers

Table 5-67 (Continued)

Orsay Physics S.A. Customers

Table 5-68

Veeco Instruments

Table 5- 69

Selected Microscopy Vendors

Table 5-70

Selected Atomic Force Microscope Manufacturers

Abstract

Breakthrough technology in microscopy brings advancements that provide customers with the power to discover things they have never seen before, and to solve problems never before solvable.

Microscope markets are segmented as optical microscopes, electron microscopes, scanning probe microscopes, and focused ion beam microscopy. Optical microscopes are light microscopes. The optical microscope is limited in the minimum size and nature of the features it can resolve by manufacturability constraints and the physics of light. While optical microscopes once accounted for the bulk of all microscopes sold in the world, today their percentage of total revenue is shrinking.

New microscopy technologies have been developed to overcome the limitations of light microscopes. Electron, scanning probe, and focused ion beam microscopy are essential aspects of different approaches to visualization at the nanoparticle level. The field of microscopy continues to evolve rapidly, as new requirements and imaging technologies are developed.

Technology integration, marking the convergence of information technology and digital imaging, is expected to change standard laboratories into advanced research centers. Current innovations in the microscopy industry are towards development of microscopes with higher precision and resolution.

Developments in image restoration, reconstruction, and other related fields will continue to influence the industry.

Innovations in electronics, engineering and industrial materials permit the industry to effectively overcome conventional barriers, allowing new systems to evolve based on new technologies.

Custom-assembled systems are based on modular approaches to product delivery. Platforms are implemented as frameworks that accept any of a variety of modules. In this manner customization is supported in the microscope industry. These custom-assembled systems enable end users incorporate existing workflow.

The microscope markets are driven by the need for research facilities to attract the most qualified researchers. The best researchers are attracted to good equipment. They will move to where the best equipment is. For enterprises and universities to land and hang on to leading researchers, they have to upgrade their equipment or those people are gone in a year.

The research and industrial use of imaging has shifted rapidly with the increasing significance of nanotechnology. To look at particles on the nano-scale requires increased sophistication and use of more expensive imaging equipment. This means that fewer organizations can afford the imaging equipment needed to stay competitive and that those organizations that can afford the very expensive imaging equipment will tend to be quite large.

Nanotechnology funding at $8.5 billion in 2008 is anticipated to increase rapidly as countries respond ot the economic meltdown. Every dollar invested in nanotechnology research turns $5 in tax dollars within a year and continues to provide that level of taxes for the next 20 to 50 years. This is a very good investment.

Countries are learning that they need to compete at a level of industrial development in the new global economy. The financial meltdown represents at its core the disintegration of national boundaries in the traditional sense. In its place are global enterprises based in a particular country, providing tax dollars to that base nation.

In this global economy, innovation is central. Innovation is based on software systems that improve productivity. Software is used to manage information and make it more accessible. Innovation improves enterprise and business decision making. Nanotechnology and electron microscopes are a central aspect of this global initiative.

FEI has had momentum in the microscope research markets unmatched by any competitor. The wins in the research market are significant because the nanotechnology techniques being developed there will work for another generation, driving markets in every segment as the research in nanotechnology being conducted now provides technology that will flow out into industry and government at a rapid pace.

FEI Company (Nasdaq:FEIC) high-resolution imaging and analysis system Titan(3(TM)) 80-300 scanning/transmission electron microscope (S/TEM) competitive win in the National Institute for Materials Science (NIMS) and King Abdullah University of Science and Technology (KAUST) of Saudi Arabia bring enormous opportunity to the company.

Nanoparticles are so tiny that good technology is a basic part of the industry. The best researchers prefer the FEI technology, giving the company significant competitive advantage.

IBM has extended 3D MRI to the Nanoscale. IBM Research (NYSE: IBM) scientists, in collaboration with the Center for Probing the Nanoscale at Stanford University, have demonstrated magnetic resonance imaging (MRI) with volume resolution 100 million times finer than conventional MRI.

Microscope market forecasts indicate that markets at $3.5 billion in 2008 are anticipated to reach $7.7 billion by 2015. Growth is stimulated by worldwide government investment in innovation in response to the meltdown of financial markets.

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