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The Global Pain Market, 2008-2023

Published by: Visiongain

Published: Nov. 13, 2008 - 102 Pages


Table of Contents


1 Executive Summary

1.1 The Pharmaceutical Pain Market Review: Entering a Crucial Period

1.2 Aims, Scope and Format of the Report

2 Introduction to Pain

2.1 What is Pain?

2.1.1 Historical aspects of Pain

2.2 Pain Pathways

2.2.1 WHO Pain Ladder

2.3 Classification and Types of Pain

2.3.1 Acute Pain

2.3.2 Chronic Pain

2.3.2.1 Psychosocial Effects of Chronic Pain

2.3.2.2 The Financial Burden of Chronic Pain

2.3.2.3 Chronic Cancer Pain

2.3.2.4 Breakthrough Cancer Pain

2.4 Neuropathic Pain

2.4.1 Distinguishing Neuropathic Pain

2.5 Neurochemistry of Pain

2.5.1 Prostaglandins

2.5.2 Opioids

2.6 Pain Treatments

2.7 OTC Pain Relievers


3 An Overview of the Global Pain Pharmaceutical Market 2008-2023

3.1 The Global Pain Pharmaceutical Market Analysis

3.1.1 Celebrex Currently Leads the Pain Pharma Market

3.1.2 The Non-Narcotics Segment Currently Dominates the Pain Market - But Will This Last?

3.2 Major Success in the Pain Pharmaceutical Market Has Proved to Be Elusive to Date

3.3 While the Past Has Been Difficult for Pain Management, There is Optimism for the Future


4 The Global Non-Narcotics Market 2008-2023

4.1 Non-Narcotics Market Analysis

4.2 Efferalgan Currently Leads the Non-Narcotics Market - But Will This Last?

4.2.1 Development of Efferalgan (Paracetamol)

4.3 Tylenol Set to Reach Blockbuster Status

4.3.1 Development of Tylenol (Paracetamol)

4.4 Aspirin Bayer - Huge Amount of Line Extensions Keeping Sales Up

4.4.1 Aspirin Bayer (Acetylsalicylic Acid)

4.5 Advil Set to Exhibit Strong Growth?

4.5.1 Advil (Ibuprofen)

4.6 Tramal - How Will Sales Develop?

4.6.1 Development of Tramal (Tramadol)

4.7 The Non-Narcotics Market Currently Dominates the Pain Industry


5 The Global Narcotics Market 2008-2023

5.1 Narcotics Market Analysis

5.2 Oxycontin - Beset by Major Challenges

5.2.1 Development of Oxycontin (Oxycodone)

5.3 Duragesic

5.3.1 Development of Duragesic (Fentanyl)

5.4 Oxycodone TEVA

5.4.1 Oxycodone

5.5 Fentanyl MYLA - How Will Sales Develop?

5.5.1 Fentanyl

5.6 Fentanyl NOVT - How Will Sales Develop?

5.7 Total Sales in the Narcotics Market Will Increase Despite Being Crowded


6 The Global Anti-Arthritic Market 2008-2023

6.1 Anti-Arthritic Market Analysis

6.2 Pfizer's Celebrex Dominates the Market, But Will This Last?

6.2.1 Development of Celebrex (Celecoxib)

6.3 Voltaren - How Will Sales Develop?

6.3.1 Development of Voltaren (Diclofenac)

6.4 Arcoxia Has Reduced Gastro Intestinal Effects

6.4.1 Development of Arcoxia (Etoricoxib)

6.5 Mobic Will Suffer from Generic Competition

6.5.1 Development of Mobic (Meloxicam)

6.6 Arthrotec Will Decline in Growth

6.6.1 Development of Arthrotec (Diclofenac/Misoprostol)

6.7 Rises Predicted for Global Arthritis Market


7 The Global Anti-Migraine Market 2008-2023

7.1 Anti-Migraine Market Analysis

7.2 GSK's Blockbuster Imitrex/Imigran - How Will Sales Develop?

7.2.1 Development of Imitrex/Imigran (Sumatriptan)

7.3 Merck & Co's Maxalt - The New Market Leader Perhaps?

7.3.1 Development of Maxalt (Rizatriptan)

7.4 Zomig Shows Positive Growth

7.4.1 Development of Zomig (Zolmitriptan)

7.5 Relpax - How Will Sales Develop?

7.5.1 Development of Relpax (Eletriptan)

7.6 Naramig - How Will Sales Develop?

7.6.1 Development of Naramig (Naratriptan)

7.7 What Does the Future Hold for Migraine Therapy?

7.8 What are the Unmet Needs in the Management of Migraine


8 SWOT Analysis

8.1 SWOT Analysis of the Global Pain Market

8.2 Market Drivers

8.3 Market Restraints

8.4 The Pain Market Suffered After the Withdrawal of COX-2 Inhibitors

8.5 Lack of Adequate Reimbursement Limits Potential of Pain Drugs

8.6 Patients Dependent on Reformulations of Existing Drugs

8.7 The Narcotics Market Suffers from Serious Side Effects

8.8 The Under-Treatment of Pain

8.9 How Might These Findings Affect the Market for Pain Drugs?

8.10 The Future of the Pain Market - Closing Comments

8.10.1 Shortcomings in the Attitude Towards Pain Management Illustrate the Need for the Proper Use of New and Existing Pain Management Therapies

8.10.2 Analgesic Effect of Established Drugs for Other Diseases Will Continue to be of Relevance to the Pain Management Market

8.10.3 Personalised Pain Management Therapy


9 Pipeline Products for the Treatment of Pain

9.1 The Pipeline in the Pain Market is Large and Expanding

9.2 The Potential of the Pain Market Has Encouraged R&D Efforts

9.3 Innovation Rules for Early-Stage Pipeline Drugs

9.4 Late-Stage Pipeline Products in the Non-Narcotics Market

9.5 Late-Stage Pipeline Products in the Narcotics Market

9.6 Late-Stage Pipeline Products in the Anti-Arthritic Market

9.7 Late-Stage Pipeline Products in the Anti-Migraine Market

9.8 The Pain Pipeline Shows Short- and Long-Term Potential


10 Future Therapies

10.1 Cannabinoids and Pain: An Alternative to Opioids?

10.2 Experimentally Induced Acute Pain

10.3 Post Surgical Acute Pain

10.4 Chronic Pain

10.5 Sativex

10.5.1 European Phase III Trials of Sativex

10.5.2 Sativex Approved for Cancer Pain

10.6 Cannabinoids and Pain: a Lucrative Market?

10.7 The Future of Pain Research

10.8 Advanced Drug Delivery

10.8.1 Delivery of Poorly-Soluble Drugs

10.8.2 Examples of Poorly-Water-Soluble Drugs


11 Conclusions

11.1 The Pain Market is Heading for Consistent Financial Growth

11.2 Will the Non-Narcotics Segment Dominate the Pain Market in Future?

11.3 The Narcotics Market Will be Hampered by Controversial Issues

11.4 The Anti-Arthritic Market Shows No Signs of Slowing Down

11.5 The Anti-Migraine Market Will Suffer Due to Patent Expiry of Key Products

11.6 Major Success in the Pain Pharmaceutical Market Has Proved to Be Elusive to Date

11.7 Why Growth in the Pain Market Will Continue

List of Tables

Table 3.1 The Global Pain Pharmaceutical Market Forecast ($m), 2008-2023

Table 3.2 Revenues ($m), 6-Year CAGR (%) and Market Share (%) for the Leading Pain Markets, 2007 & 2013

Table 3.3 Top Ten Products in the Pain Market ($m), 2007

Table 4.1 The World Non-Narcotics Market ($m) Forecast 2008-2023

Table 5.1 The World Narcotics Market ($m) Forecast 2008-2023

Table 6.1 The World Anti-Arthritic Market ($m) Forecast 2008-2023

Table 7.1 The World Anti-Migraine Market ($m) Forecast 2008-2023

Table 8.1 A SWOT Chart for the Pain Market, 2008-2013

Table 9.1 Late-Stage Non-Narcotic Pipeline Drugs for Pain, 2008

Table 9.2 Late-Stage Narcotic Pipeline Drugs for Pain, 2008

Table 9.3 Late-Stage Anti-Arthritic Pipeline Drugs for Pain, 2008

Table 9.4 Late-Stage Anti-Migraine Pipeline Drugs for Pain, 2008


List of Figures

Figure 3.1 The Global Pain Pharmaceutical Market Revenue Forecast ($m), 2008-2023

Figure 3.2 Leading Pain Markets’ Revenue ($m) Comparison, 2007 & 2013

Figure 3.3 Leading Pain Sectors’ Market Share (%), 2007

Figure 3.4 Leading Pain Sectors’ Market Share (%), 2013

Figure 4.1 Non-Narcotics World Market Revenue Forecast ($m), 2008-2023

Figure 4.2 Efferalgan Revenue Forecast ($m), 2008-2023

Figure 4.3 Tylenol Revenue Forecast ($m), 2008-2023

Figure 4.4 Aspirin Bayer Revenue Forecast ($m), 2008-2023

Figure 4.5 Advil Revenue Forecast ($m), 2008-2023

Figure 4.6 Tramal Revenue Forecast ($m), 2008-2023

Figure 5.1 Narcotics World Market Revenue Forecast ($m), 2008-2023

Figure 5.2 Oxycontin Revenue Forecast ($m), 2008-2023

Figure 5.3 Duragesic Revenue Forecast ($m), 2008-2023

Figure 5.4 Oxycodone TEVA Revenue Forecast ($m), 2008-2023

Figure 5.5 Fentanyl MYLA Revenue Forecast ($m), 2008-2023

Figure 5.6 Fentanyl NOVT Revenue Forecast ($m), 2008-2023

Figure 6.1 Anti-Arthritic World Market Revenue Forecast ($m), 2008-2023

Figure 6.2 Celebrex Revenue Forecast ($m), 2008-2023

Figure 6.3 Voltaren Revenue Forecast ($m), 2008-2023

Figure 6.4 Arcoxia Revenue Forecast ($m), 2008-2023

Figure 6.5 Mobic Revenue Forecast ($m), 2008-2023

Figure 6.6 Arthrotec Revenue Forecast ($m), 2008-2023

Figure 7.1 Anti-Migraine World Market Revenue Forecast ($m), 2008-2023

Figure 7.2 Imitrex/Imigran Revenue Forecast ($m), 2008-2023

Figure 7.3 Maxalt Revenue Forecast ($m), 2008-2023

Figure 7.4 Zomig Revenue Forecast ($m), 2008-2023

Figure 7.5 Relpax Revenue Forecast ($m), 2008-2023

Figure 7.6 Naramig Revenue Forecast ($m), 2008-2023

Figure 11.1 The Global Pain Pharmaceutical Market Revenue Forecast ($m), 2008-2023


Companies listed:


AstraZeneca

Abbott

Acura

Alpharma

Anesiva

Astellas

Bayer

Biovail

Bristol Myers Squibb

Daiichi Sankyo

Dr. Reddy’s Laboratories

Eisai

Ethypharm

Gruenenthal

GSK

GW pharmaceuticals

Horizon

Idea

Javelin

Johns Hopkins University

Johnson & Johnson

Kowa

Labopharm

MAP Pharmaceuticals

Meda

Merck & Co

NicOx

Novartis

Ono

Pacira Pharmaceuticals

Pain Therapeutics

Paion

Pfizer

PLx Pharma

Pozen

Purdue Pharma

QRxPharma

Ranbaxy

Recordati

Roxro

Shionogi

Symbollon

Teva

UCB

Wex

Winston Laboratories

Zogenix




Abstract

The global pain market generated total sales of $34bn in 2007 - but what will the figures be in the next 5 and 10 years? This report tells you.

The pain market has marked strengths and advantages, but is also limited by problems and concerns. The market will be driven by new drugs and reformulations of existing ones - but which drugs will be most successful? The incidence of pain is increasing rapidly, what some experts call a pain epidemic - so the opportunities available to an additional blockbuster drug is significant. The prevention and treatment of pain is already one of the highest priorities for healthcare authorities in the world, yet for mature markets pain drug sales have fallen. However, visiongain believes that this market has strong growth potential, despite the prospect of generic competition for leading branded products.

The pain market contained four blockbuster drugs in 2007. Visiongain predicts that there will be room for more blockbuster drugs in that market segment during the years ahead as new products are launched, replacing older products. There is great potential for treatments with greater safety, efficacy and tolerability. This report - The Global Pain Market, 2008-2023 - provides analysis and forecasts for the overall pain market and its principal subdivisions, as well as for leading products within those categories. This study also highlights promising pipeline developments and important contemporary issues, especially commercial drivers and restraints.

In particular, The Global Pain Market, 2008-2023 analyses global markets for the following groups of pain treatment:
  • Non-narcotics
  • Narcotics
  • Anti-arthritic treatments
  • Anti-migraine treatments.
This report delivers:
  • Key analysis split by region and class
  • Future market analysis right through to 2023
  • Analysis of key brands, generics, strategies in-place today and future strategies over the next 15 years
  • Analysis of key players in the pain market, current and future licensing strategies
This report examines the global pain drug market critically through a comprehensive review of available information. Sources used include internal databases, industrial databases, commercial news, company reports, published reports and economic research. Visiongain applies in-house financial forecasting, qualitative analyses and the assessment of unmet needs to provide a comprehensive market report with detailed analysis and informed opinion.

In particular, The Global Pain Market, 2008-2023 concentrates on the following essential aspects of the market:
  • Forecast for the worldwide pain pharmaceutical market from 2008 to 2023
  • Forecasts for the principal submarkets from 2008 to 2023
  • Commercial prospects for the market-leading drugs, with sales forecasts from 2008 to 2023
  • Drivers and restraints in the pain market
  • Opportunities and threats in the pain market
  • Future therapies that will drive growth in this market
  • Pipeline developments with significant commercial potential
  • Currently marketed drugs with blockbuster potential
  • Discussion of unmet therapeutic needs and relative advantages of products.
Why you should buy this report:
  • To receive a comprehensive analysis of the prospects for pain drugs from 2008 to 2023
  • To discover predicted revenues, growth rates and other key metrics for leading pain treatments from 2008 to 2023
  • To discover “hot” pipeline developments and up-and-coming products
  • To determine the forces that influence the market for pain drugs:
  • Competitive characteristics of the market
  • Drivers
  • Restraints
  • Strengths, weaknesses, opportunities and threats in that market
  • To find out where the market is heading - both technologically and commercially - from 2008 onwards.


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