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Anticoagulants

Published by: Global Industry Analysts

Published: Oct. 1, 2008 - 327 Pages


Table of Contents


I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations

Disclaimers

Data Interpretation & Reporting Level

Quantitative Techniques & Analytics

Product Definitions And Scope Of Study

II. EXECUTIVE SUMMARY

1. Worldwide Anticoagulants Market

Global Market Overview

Current and Future Scenario

Major Markets - Products

Injectable Anticoagulants - On An Up Trend

Low Molecular Weight Heparins - Ruling the Roost

Major Markets - Regional

United States - The Largest Market

Europe - The Second Largest Market

2. Industry Overview

The Pharmaceuticals Industry

Industry Framework

Regulatory Price Controls - Present and Future

Consolidations Driving the Industry

Patent Expiries Giving Way to Generic Drugs

Anticoagulants Sector

A Snapshot of Available Therapies

An Insight into Currently Available Antithrombotic Drugs

Weaknesses of Available Therapies

Forces Driving the Market

Oral Anticoagulants Market

Injectable Anticoagulants Market

Heparin Market

LMWH Market

3. Market Dynamics

Drug Advancements Drive Anticoagulant Market

Niche Markets - The New Target for Drug Makers

An Opportunity to Grow Further

Geriatric Patients - At High Risk of Blood Clots

Improved Anticoagulant Agents for Children Group

Growing Demand for Self-Testing

LMWHs Eases Outpatient Management

Concern Over Underutilization of Warfarin

Anticoagulants to Lose UA/AMI Markets to Antiplatelets

Influx of New Drugs: Invigorates the Market

Novel Heparins: Enhances Market Potential

Anticoagulant Therapy During Pregnancy Improves Outcomes

New Therapies: Need of the Hour

Anticoagulant Therapy in IPF: Reduces Mortality Risk

Failure of Exanta

4. Product Overview

Introduction to Anticoagulants

Evolution of Anticoagulants

Blood Coagulation - A Major Concern

Anticoagulants Disrupts Metastatic Events

The Coagulation Cascade

Coagulation Factors Found in the Coagulation Cascade

Precautions

Side Effects

Hemorrhagic Symptoms and Side Effects

Impediments

Potential Candidates for Anticoagulation

Alternative Therapies to Anticoagulants

Thrombolytics - Another Major Solution for Thrombosis

Anticoagulants Drug Class

Oral Anticoagulants

Oral Anticoagulants Induces Calcification

Warfarin

Advantages and Alternatives

Side Effects

Limitations

Coumadin

Injectable Anticoagulants

Heparin - The Backbone of Injectable Anticoagulants

Unfractionated Heparin

Advantages and Alternatives

Limitations

Low Molecular Weight Heparins

Costs

Impediments

Lovenox/Clexane (enoxaparin)

Approved Indications for Lovenox:

Advantages and Alternatives

Fragmin (dalteparin)

Approved Indications for Fragmin Use:

Contradictions

Precautions

Fraxiparine (nadroparin)

Innohep (tinzaparin)

Contraindications

Side Effects

Other Serious Adverse Events Associated with Innohep

Precautions

Normiflo (ardeparin)

Clivarine (reviparin)

Summary of Available LMWHs

Non-Heparin Injectables

Arixtra (fondaparinux)

Contraindications

Market and Market Participants

Angiomax (bivalirudin)

Advantages

Contraindications

Side Effects

Argatroban/ Novastan

Side Effects

Precautions

Refludan (lepirudin)

Orgaran (danaparoid sodium)

Contraindications

Side Effects

Caution

Precaution

A Comparative Analysis of Various Direct Thrombin Inhibitors

Other Anticoagulants

Lithium Heparin

EDTA

Citrate

Oxalate

5. A Comparative Study of Anticoagulant Therapies

A Comparative Study of Warfarin Against LMWHs

A Comparative Study of LMWH Against UFH

A Comparative Study of Heparin Against Angiomax

A Comparative Study of Arixtra Against UFH and LMWH

A Comparative Study of Angiomax Against UFH and LMWH

6. Areas of Indication

Indications for Anticoagulant Use

Venous/DVT Thrombosis Indications

Venous Thromboembolism (VTE)

Deep Vein Thrombosis (DVT)

Pulmonary Embolism (PE)

Orthopedic (Hip or Knee Replacement) Surgery

General Surgery

Cancer

Arterial Thrombosis Indications

Arterial Thrombosis

Acute Coronary Syndromes (ACS)

Atrial Fibrillation (AF)

Unstable Angina (UA)

List of Approved Anticoagulants for Unstable Angina

Myocardial Infraction (MI)

Non-ST Segment Elevation MI

List of Approved Anticoagulants for Non-ST Segment Elevation Myocardial

Infraction

Percutaneous Transluminal Coronary Angioplasty (PTCA)

List of Approved Anticoagulants for Angioplasty Procedures

Heparin Induced Thrombocytopenia (HIT) Indications

HIT Type I

HIT Type II

Heparin Induced Thrombocytopenia with Thrombosis (HITTS)

Other Indications

Hemodialysis

7. Drug Development Pipeline

Select Anticoagulants Under Pipeline

Idraparinux - Sanofi-Aventis

0673 - Sanofi-Aventis

BIBR1048MS - Boehringer Ingelheim

8. Product Introductions

Boehringer Receives EU Approval for Pradaxa

Sanofi-Aventis Receives Approval for Clexane® in Japan

ParagonDx Receives US FDA Approval for its Rapid Genotyping Assay

Lannett Obtains US FDA Approval for Dipyridamole Tablets

Kimball Introduces New Pharmacogenetic Test

Roche Launches an Improved Point-of-Care Anticoagulation Monitoring System

Danish Agency Grants Approval for Anticoagulant Clinical Trials

EMEA Approves ARIXTRA® of GlaxoSmithKline

FDA Approves ANDAs of PLIVA

FDA Approves ARIXTRA Injection of GSK

Japanese Ministry Approves Arixtra of GSK

Eisai Obtains FDA Approval for Fragmin

Sanofi-Aventis' Lovenox® Obtains FDA Approval for Acute Cardiac Care

Zydus Cadila's Warfarin Secures Approval from US FDA

Momenta Pharmaceuticals Seeks Approval for M-Enoxaparin

Mitsubishi Pharma Releases Argatroban in Europe

Regado Develops Anticoagulant

9. Recent Industry Activity

PAION Acquires CeNes Pharmaceuticals

PAION Announces Acquisition of Global Rights to Trigen’s flovagatran

Biological E Collaborates with Choncept and Heparinex

Bayer’s Market Expansion

B. Braun Recalls Heparin Sodium Based Injection Solutions

Baxter Recalls Heparin Sodium Vials

Celgene Acquires Pharmion

BMS Collaborates with Pfizer

Medicines Company Reacquires European Rights for Angiox

HemoSense and LabCorp Sign Agreement for Supply of INRatio System

Sanofi-Aventis Acquires Rights for Panaldine from Daiichi

Alchemia Inks Marketing Alliance with Dr Reddy’s for Heparin

Inverness Announces Acquisition of HemoSense

ev3, FoxHollow Complete Merger

Osmetech Signs Licensing Agreement with Marshfield Clinic

Mitsubishi and Tanabe Agree to Merge

Artisan and A-Bio Form Alliance

Archemix and Nuvelo Announces Expansion of Alliance

American Capital Acquires Scientific Protein Laboratories’ One Stop Buyout™

Bristol-Myers to Start New Facility in Massachusetts

AstraZeneca Stops Development of Exanta

Pfizer Enters into Agreement with BPC

AstraZeneca Pacts with Targacept

GlaxoSmithKline Acquires ID Biomedical

Direct Capital Buys Stake in NZP

Archemix and Nuvelo Stop Development of ARC183

Novartis Purchases Bristol-Myers’ US/Canadian Consumer Medicine Operations

Akers Pacts with Cardinal Health

10. Focus on Select Global Players

AstraZeneca PLC (UK)

Barr Laboratories Inc (USA)

Bristol-Myers Squibb Company (USA)

Celgene Corporation (USA)

GlaxoSmithKline plc (UK)

Mitsubishi Tanabe Pharma Corporation (Japan)

Pfizer Inc (USA)

Sanofi-Aventis (France)

11. Global Market Perspective

Table 1: World Recent Past, Current & Future Analysis for Anticoagulants by Geographic Region/Country - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 2: World Long-term Projections for Anticoagulants by Geographic Region/Country -

US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales

Figures in US$ Million for Years 2011 through 2015 (includes corresponding

Graph/Chart)

Table 3: World 10-Year Perspective for Anticoagulants by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 4: World Recent Past, Current & Future Analysis for Oral Anticoagulants by Geographic Region/ Country - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 5: World Long-term Projections for Oral Anticoagulants by Geographic Region/Country

- US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales

Figures in US$ Million for Years 2011 through 2015 (includes corresponding

Graph/Chart)

Table 6: World 10-Year Perspective for Oral Anticoagulants by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 7: World Recent Past, Current & Future Analysis for Injectable Anticoagulants by Geographic Region/Country - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 8: World Long-term Projections for Injectable Anticoagulants by Geographic

Region/Country - US, Japan, Europe, and Rest of World Markets Independently Analyzed with

Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding

Graph/Chart)

Table 9: World 10-Year Perspective for Injectable Anticoagulants by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 10: World Recent Past, Current & Future Analysis for Injectable Anticoagulants by Product Segment - Unfractionated Heparin and Low Molecular Weight Heparin Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 11: World Long-term Projections for Injectable Anticoagulants by Product Segment -

Unfractionated Heparin and Low Molecular Weight Heparin Markets Independently Analyzed

with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes

corresponding Graph/Chart)

Table 12: World 10-Year Perspective for Injectable Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Unfractionated Heparin and Low Molecular Weight Heparin Markets for the Years 2003, 2008 & 2012

Table 13: World Recent Past, Current & Future Analysis for Unfractionated Heparin by Geographic Region/Country - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 14: World Long-term Projections for Unfractionated Heparin by Geographic

Region/Country - US, Japan, Europe, and Rest of World Markets Independently Analyzed with

Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding

Graph/Chart)

Table 15: World 10-Year Perspective for Unfractionated Heparin by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 16: World Recent Past, Current & Future Analysis for Low Molecular Weight Heparin s by Geographic Region/Country - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 17: World Long-term Projections for Low Molecular Weight Heparin by Geographic

Region / Country - US, Japan, Europe, and Rest of World Markets Independently Analyzed

with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes

corresponding Graph/Chart)

Table 18: World 10-Year Perspective for Low Molecular Weight Heparin by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

III. MARKET

1. The United States

A. Market Overview

Outlook

Atrial Fibrillation - A Key Risk Factor

Regulatory Route to the US Market

Price Controls

US Anticoagulants Market

US Heparin Market

Hinging on Market Opportunities

Generics - Threatening Branded Anticoagulants

List of Patent Protected Anticoagulants in the US

Ignorance - A Major Hindrance

Future Challenges and Growth Drivers

US Emerging Anticoagulant Market

US Emerging Anticoagulants Market: Products in the Pipeline

Product Introductions

Strategic Corporate Developments

Focus on Select Players

B. Market Analytics

Table 19: US Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 20: US Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 21: US 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

2. Japan

A. Market Overview

Pharmaceutical Industry in Japan

Regulatory Procedure in Japan

Drug Pricing in Japan

Anticoagulants Market in Japan

Rising Incidence of Pulmonary Thromboembolism

Product Introductions

Strategic Corporate Developments

Mitsubishi Tanabe Pharma Corporation - A Major Player

B. Market Analytics

Table 22: Japanese Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 23: Japanese Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 24: Japanese 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

3. Europe

A. Market Overview

An Analysis of Major Regional Markets

France - A Major Market

UK - High Growth Potential Market

Pharmaceutical Industry in Europe

Regulatory Procedure in Europe

Anticoagulants Market in Europe

List of Patent Protected Anticoagulants in Europe

Injectable Sector - Booming Ahead

Market in High Need of an Ideal Therapy

Product Introductions

Strategic Corporate Development

B. Market Analytics

Table 25: European Recent Past, Current & Future Analysis for Anticoagulants by Geographic Region/Country - France, Germany, Italy, UK, Spain, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 26: European Long-term Projections for Anticoagulants by Geographic Region/Country - France, Germany, Italy, UK, Spain, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 27: European 10-Year Perspective for Anticoagulants by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK, Spain, and Rest of Europe Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 28: European Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 29: European Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 30: European 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

3a. France

A. Market Overview

Sanofi-Aventis - A Major Player

B. Market Analytics

Table 31: French Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 32: French Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 33: French 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

3b. Germany

A. Market Overview

Market Drivers for Injectable Anticoagulants

Anticoagulants Growth Drive European POC Testing Market

Strategic Corporate Developments

B. Market Analytics

Table 34: German Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 35: German Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 36: German 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

3c. Italy

Market Analysis

Table 37: Italian Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 38: Italian Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 39: Italian 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

3d. The United Kingdom

A. Market Overview

Outlook

Growing AF Market for Warfarin

Select Players

Strategic Corporate Developments

B. Market Analytics

Table 40: UK Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 41: UK Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 42: UK 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

3e. Spain

Market Analysis

Table 43: Spanish Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 44: Spanish Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 45: Spanish 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

3f. Rest of Europe

Market Analysis

Table 46: Rest of Europe Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 47: Rest of Europe Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 48: Rest of Europe 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

4. Rest of World

A. Market Overview

Anticoagulants Market in Australia

Strategic Corporate Developments

B. Market Analytics

Table 49: Rest of World Recent Past, Current & Future Analysis for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 50: Rest of World Long-term Projections for Anticoagulants by Product Segment - Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 51: Rest of World 10-Year Perspective for Anticoagulants by Product Segment - Percentage Breakdown of Dollar Sales for Oral Anticoagulants and Injectable Anticoagulants (Unfractionated Heparin and Low Molecular Weight Heparin) Markets for the Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)

IV. COMPETITIVE LANDSCAPE 179 $995

Total Companies Profiled: 51 (including Divisions/Subsidiaries - 55)

Region/Country Players

The United States28

Canada1

Japan 2

Europe 13

France 1

Germany4

The United Kingdom 4

Rest of Europe 4

Asia-Pacific (Excluding Japan)9

Middle East 2


Abstract

This report analyzes the worldwide markets for Anticoagulants in Millions of US$. The major product segments analyzed are Oral Anticoagulants, and Injectable Anticoagulants (Unfractionated Heparin, and Low Molecular Weight Heparin). The report provides separate comprehensive analytics for the US, Japan, Europe, and Rest of World. Annual forecasts are provided for each region for the period of 2000 through 2015. The report profiles 51 companies including many key and niche players worldwide such as AstraZeneca PLC, Barr Laboratories Inc, Bristol-Myers Squibb Company, Celgene Corporation, GlaxoSmithKline plc, Mitsubishi Tanabe Pharma Corporation, Pfizer Inc, and Sanofi-Aventis. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

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