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All Change in the US Pharma Market?

Published by: Espicom Healthcare Intelligence

Published: Jun. 18, 2008 - 186 Pages


Table of Contents


Foreword

EXECUTIVE SUMMARY

Industry Overview

Branded company sales overview

Leading Originator Companies, Global Pharmaceutical Revenues, 2006-07 (US$ millions)

Exposure to generics

% of Global Revenues Likely to Face Generic Competition, 2008-12

Branded defence strategies

Incremental innovation

Extended-release formulations

Second-generation products

Citizen petitions

Deals with generic companies

Authorised generics

Biologics

Leading Originator Companies, PHSA Biologic Revenues 2007

FDCA biologics

Generic Approvals and Launches

Pharmaceutical Products Estimated to Face Widespread Generic Competition by 2012

Pharmaceutical Products Estimated to Face Limited Generic Competition by 2012

Pharmaceutical Products Estimated to Face No Generic Competition by 2012

Biologic Products: No Generic Competition to 2012

2007 Global Revenues Subject to Generic Competition by 2012 (US$ millions)

Generic launches „at risk‟

Summary of „at risk‟ US Generic Launches, 2006-08

Research-Based Company Profiles

Abbott Laboratories

Sales Intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Biaxin

Depakote/Depakote ER

Humira

Kaletra

Omnicef

Synthroid

Tricor

Amgen

Sales Intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

US Product Sales Data, 2006-07 (US$ millions)

Aranesp

Epogen

Neulasta

Neupogen

Enbrel

Sensipar

Vectibix

AstraZeneca

Sales Intro

Exposure to generics 2008-12

Defence Strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

US Product Sales Data, 2006-07 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (US$ millions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Arimidex

Atacand

Casodex

Crestor

Nexium

Prilosec

Pulmicort

Seroquel

Toprol XL

Zoladex

Zomig

Boehringer Ingelheim

Sales Intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (euro millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (euro millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Aggrenox

Combivent

Flomax

Micardis

Mirapex

Mobic

Spiriva

Bristol-Myers Squibb

Sales Intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

US Product Sales Data, 2006-07 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (US$ billions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (US$ billions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Abilify

Avapro/Avalide

Baraclude

Erbitux

Orencia

Plavix

Pravachol

Reyataz

Sprycel

Sustiva

Eli Lilly

Sales Intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

US Product Sales Data, 2006-07 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (US$ millions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Alimta

Byetta

Cialis

Cymbalta

Evista

Forteo

Gemzar

Humatrope

Strattera

Zyprexa

Insulin products

GlaxoSmithKline

Sales Intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (£ millions)

US Product Sales Data, 2006-07 (£ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (£ billions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (£ billions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Advair Diskus

Augmentin

Avandia

Avodart

Combivir

Coreg

Epzicom

Flonase

Flovent

Imitrex

Lamictal

Paxil

Requip

Trizivir

Valtrex

Wellbutrin

Zofran

Johnson & Johnson

Sales intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (US$ billions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Aciphex

Concerta

Duragesic

Levaquin

Procrit

Remicade

Risperdal

Topamax

Merck & Co

Sales intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Cancidas

Cozaar

Emend

Fosamax

Januvia

Maxalt

Primaxin

Proscar/Propecia

Singulair

Trusopt/Cosopt

Zocor

Novartis

Sales intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

US Product Sales Data, 2006-07 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (US$ billions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (US$ billions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Diovan

Exelon

Famvir

Femara

Focalin

Gleevec

Lamisil

Lescol XL

Lotrel

Sandostatin

Trileptal

Zometa

Pfizer

Sales Intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

2007 Revenues Exposed To Probable Generic Competition, 2008-12 (US$ billions)

2007 Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Aricept

Aromasin

Caduet

Camptosar

Cardura

Celebrex

Chantix

Detrol/Detrol LA

Genotropin

Geodon Oral

Lipitor

Lyrica

Neurontin

Norvasc

Relpax

Sutent

Vfend

Viagra/Revatio

Xalatan

Zithromax

Zoloft

Zyrtec

Zyvox

Roche

Sales intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (CHF millions)

US Product Sales Data, 2006-07 (CHF millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (CHF millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (CHF millions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Avastin

Boniva

CellCept

Herceptin

Kytril

Lucentis

Nutropin

Pegasys

Rituxan

Tamiflu

Tarceva

Valcyte

Xeloda

Xenical

Xolair

Sanofi Aventis

Sales intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (euro millions)

US Product Sales Data, 2006-07 (euro millions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (euros millions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Actonel

Allegra

Amaryl

Ambien

Avapro

Copaxone

Deprocon

Eloxatine

Lantus

Lovenox

Nasacort

Plavix

Taxotere

Altace

Uroxatral

Wyeth

Sales intro

Exposure to generics 2008-12

Defence strategies

Product Summary, 2006-2012

Summary of Products Reviewed

Summary by Year

Global Product Sales Data, 2006-07 (US$ millions)

US Product Sales Data, 2006-07 (US$ millions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (US$ billions)

2007 Global Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (£ billions)

2007 US Revenues Exposed To Probable Generic Competition, 2008-12 (% of Total)

Effexor

Prevnar

Protonix

Zosyn/Tazocin

Tygacil

Appendix: Overview of the generic application and approval system

Appendix 1: ANDA Approvals

ANDA Approvals, 2002-08

Abstract

This extensive report provides a unique analysis of the likely impact of generic competition in the US pharma market. Now you can...

Identify the 150 products which could be subject to generic competition over the next 5 years

Evaluate the level of impact on each product

Assess the impact of generic competition on 14 leading branded companies

Understand the strategies being used by companies in defence of their products’ position
Key questions answered in this report

Which companies are at greater or lesser risk of generic competition by 2012 and what will be the impact on revenues?

What strategies has Abbott successfully employed in defence of Depakote and Tricor?

Who is benefiting from the unresolved biosimilar approval process?

AstraZeneca could have US$5.31 billion of revenue at risk by 2012 - what are the products affected and when will the impact be felt?

What lessons can be learned from the ongoing Apotex/BMS and SA litigation in relation to the world’s second best selling drug Plavix?

There is much discussion about generic competition to Lipitor, but what other products are at risk in Pfizer’s portfolio?

Why has Wyeth not sued Sun Pharmaceutical over its extended release tablet for Effexor?

Understand the developments that are driving change
All Change in the US Pharma Market?
The rise of generics, products at risk and defence strategies

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