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State of the Clinical Trials Industry 2008

Published by: CenterWatch

Published: May. 1, 2008


Table of Contents



L I S T O F F I G U R E S A N D TA B L E S

F O R E W O R D

I N T R O D U C T I O N

2007 in Review

CHAPTER O N E

Industry Sales

Ethical Pharmaceuticals: Worldwide and U.S. Sales

Medical Devices: Worldwide Sales, Largest Markets

Generic Pharmaceuticals: U.S. Sales; Percent of Total

Prescriptions Sold

Biotech

CHAPTER T W O

R&D Expenditure

Total R&D Spending, U.S. and Global

Top 10 Pharmaceutical Company R&D Spending

Top 10 Biotech Company R&D Spending

Government Sponsored and Industry Sponsored R&D Spending

Worldwide Clinical Spending

U.S. Clinical Spending

Worldwide Clinical Grants Market

NIH Budget

Clinical Grants Spending


CHAPTER T H R E E

Clinical Development

Worldwide Drugs in Development by Top Therapeutic Areas

Drugs in Preclinical and Clinical Development

Pediatric Drugs: Total Drugs and Top Areas of Pediatric Drug Testing

Mean Development Cycle Time for New Biopharmaceuticals

Delays in Development

Causes and Costs Associated with Delays

CHAPTER F O U R

Eye Ons and Pipelines

Breast Cancer

Depression

Diabetes

Diarrhea

Hepatitis C

Hypertension

Leukemia

Melanoma

Obesity

Pain

Respiratory Diseases

Vaccines

CHAPTER F I V E

Sponsors

CenterWatch U.S. Investigative Site Survey-Sponsors

CenterWatch European Investigative Site Survey-Sponsors

CenterWatch Latin American Investigative Site Survey-Sponsors

CHAPTER S I X

Contract Research Organizations

CRO Market Size

Growth in Spending

Company Valuations

CenterWatch U.S. Investigative Site Survey-CROs

CenterWatch European Investigative Site Survey-CROs

CenterWatch Latin American Investigative Site Survey-CROs

Sponsor Usage

CRO Acquisitions

CROs Costs and Performance

Academic Health Centers (AHCs)

Site Management Organizations (SMOs)

CHAPTER S E V E N

Outsourcing

Outsourcing Challenges

CenterWatch Vendor and Outsourcing Survey

Clinical Trial Laboratory Services

Use of EDC Technology

Institutional Review Boards (IRBs): Total and OHRP Registered

Electronic Health Records

CHAPTER E I G H T

Investigative Site Infrastructure and Operations

Investigator Profiles: U.S. and Worldwide

CenterWatch Physician's Survey

CenterWatch Training Survey

Clinical Research Coordinators (CRCs)

CenterWatch Investigator Meeting Survey


CHAPTER N I N E

Study Volunteers

Online Clinical Trials Information

CenterWatch Patient Experience Survey

Patient Recruitment

Clinical Trial Participation

Retention Strategies

Payment to Study Volunteers

Understanding Risks and Informed Consent

Volunteer Satisfaction With Clinical Trials

Volunteer Demographics

Health Demographics

CHAPTER T E N

U.S. Regulatory

IND Submissions

NDA Submissions and Approvals

NME Approvals

IDE Approvals

FDA Inspections

CHAPTER E L E V E N

Worldwide View

Country Attractiveness for Clinical Trials

Analysis of Investigators based on FDA1572

Canadian Clinical Trials

Australian Clinical Trials

EU Clinical Trials

Russian Clinical Trials

Japanese Clinical Trials

Korean Clinical Trials

Singapore Clinical Trials

India Clinical Trials

Latin American Clinical Trials

NIH Grants Abroad

INDEX

ABOUT CENTER WATCH

Abstract

State of the Clinical Trials Industry 2008 edition offers the newest statistics on the clinical trials industry. This comprehensive, easy-to-use resource includes over 600 charts and graphs of original, proprietary CenterWatch data examining all aspects of the global clinical trials industry. Also included are a review of the top clinical research stories of 2007 as reported by the editorial staff of The CenterWatch Monthly; as well as drug pipeline information and updates on specific disease areas.

What’s New in the 2008 Edition?
  • Over 400 New and updated data charts
  • A new chapter featuring international developments
  • Summary highlights of key points from each chapter
  • An index of each charts and company mentioned
  • An expanded table of contents and list of figures
State of the Clinical Trials Industry 2008 includes data on:
  • Proprietary data from multiple CenterWatch surveys
  • Overall R&D spending and cycle times
  • U.S. and world wide clinical research
  • Causes and costs associated with delays
  • Trial success based on company size
  • CRO market size, costs and performance
  • Site perception of sponsors and CROs
  • Regulatory submissions and approvals


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