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Chiral Chemicals

Published by: RI Technologies

Published: Mar. 1, 2008 - 380 Pages


Table of Contents



I. SCOPE AND METHODOLOGY

II. REPORT SYNOPSIS

1. Introduction

Identification of Chirality in Molecules

Chiral Parameters and Molecular Chirality

Terminology in Chiral Technology

Chiral

Chirality

Effects of Molecular Structure on Chirality:

Chiral Ligand

Chiral Catalyst

Chiroptical

Chirotopic

Stereoisomers

Racemate

Racemisation

Epimers

Epimerisation

Meso isomers

Absolute Stereochemistry

Chirality Sense

Enantiomers or Chiral Isomers

Disconnection

Synthon

Chiral Transformation

Retron

Retrosynthetic Tree

Elements of Chirality

Chiral center

Plane of Symmetry for Chirality or Chirality Plane

Axis of Chirality or Chirality Axis

Diastereoisomers

Nomenclature of Diastereomers

Diastereoselectivity

Enantiomeric excess

Diastereoisomer Excess/Diastereomeric Excess

Chiral Technology - Historical Profile (250 B.C - 1985 A.D.)

History and Background

Optical Activity

Polarization of Calcite

Chirality of Tartaric Acid

Tiny Crystals of Tartaric Acid are found to be Hemihedral

Medical Background

The First Catalytic Asymmetric Synthesis for Disease Treatment

Segmentation of Chiral Chemicals

Exhibit 1: Segmentation of Global Chiral Chemicals Market by Method of Preparation/Separation

(Traditional, Asymmetric, Biological and Other) and Application (Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other)

Exhibit 2: Segmentation of Fields in Method of Preparation/Separation (Traditional,

Asymmetric, Biological)

2. Global Market Analysis

Exhibit 3: Chiral Chemicals (2005-2012) - Global Market Analysis (Current & Future)

in US$ Billion (Graphical Representation Included)

Market Analysis by Segmentation

Analysis by Method for Preparation/Separation

Exhibit 4: Chiral Chemicals (2005-2012)-Global Market Analysis (Current and Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Billion (Graphical Representation Included)

Exhibit 5: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of Global

Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Application

Exhibit 6: Chiral Chemicals (2005-2012)-Global Market Analysis (Current and Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and Other

in US$ Billion (Graphical Representation Included)

Exhibit 7: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of Global

Market Value by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and Other

Market Analysis by Geographic Region

Analysis by Method of Preparation/Separation

Traditional

Exhibit 8: Chiral Chemicals by Traditional Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for North America, Europe, Asia-Pacific,

Japan and Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 9: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for North America, Europe,

Asia-Pacific, Japan and Rest of World

Asymmetric

Exhibit 10: Chiral Chemicals by Asymmetric Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for North America, Europe, Asia-Pacific,

Japan and Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 11: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for North America, Europe,

Asia-Pacific, Japan and Rest of World

Biological

Exhibit 12: Chiral Chemicals by Biological Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for North America, Europe, Asia-Pacific,

Japan and Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 13: Chiral Chemicals by Biological Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for North America, Europe,

Asia-Pacific, Japan and Rest of World

Other

Exhibit 14: Chiral Chemicals by Other Methods (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for North America, Europe, Asia-Pacific,

Japan and Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 15: Chiral Chemicals by Other Methods (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for North America, Europe,

Asia-Pacific, Japan and Rest of World

Analysis by Application

Pharmaceutical

Exhibit 16: Chiral Chemicals by Application in Pharmaceuticals (2005-2012) - Global Market

Analysis (Current & Future) by Geographic Region for North America, Europe, Asia-Pacific,

Japan and Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 17: Chiral Chemicals by Application in Pharmaceuticals (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for North America, Europe,

Asia-Pacific, Japan and Rest of World

Agrochemical

Exhibit 18: Chiral Chemicals by Application in Agrochemicals (2005-2012) - Global Market

Analysis (Current & Future) by Geographic Region for North America, Europe,

Asia-Pacific, Japan and Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 19: Chiral Chemicals by Application in Agrochemicals (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for North America, Europe,

Asia-Pacific, Japan and Rest of World

Flavors /Fragrances

Exhibit 20: Chiral Chemicals by Application in Flavors/Fragrances (2005-2012) - Global Market

Analysis (Current & Future) by Geographic Region for North America, Europe, Asia-Pacific,

Japan and Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 21: Chiral Chemicals by Application in Flavors/Fragrances (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region for North America,

Europe, Asia-Pacific, Japan and Rest of World

Other

Exhibit 22: Chiral Chemicals by Application in Other (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and

Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 23: Chiral Chemicals by Application in Other (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for North America, Europe,

Asia-Pacific, Japan and Rest of World

Exhibit 24: List of Major Global Companies

3. Regional Market Analysis

North America

Exhibit 25: Chiral Chemicals (2005-2012) - North American Market Analysis

(Current & Future) in US$ Billion (Graphical Representation Included)

Major Companies in North America

Albemarle Corporation (USA)

Altus Pharmaceuticals, Inc. (USA)

Beckman Coulter, Inc. (USA)

Boulder Scientific Company (USA)

Cambrex Corporation (USA)

Chiral Quest, Inc. (USA)

Chiral Technologies, Inc. (USA)

DavosPharma (USA)

Digital Specialty Chemicals (Canada)

Dow Chemical Company (USA)

Genencor (USA)

Genzyme Corporation (USA)

JASCO, Inc. (USA)

Maxygen (USA)

PDR-Chiral, Inc. (USA)

PerkinElmer, Inc. (USA)

Phenomenex, Inc. (USA)

Regis Technologies, Inc. (USA)

Rudolph Instruments, Inc. (USA)

SEDERE, Inc. (USA)

Strem Chemicals, Inc. (USA)

Synthetech, Inc. (USA)

Synthon Chiragenics Corporation (USA)

Thermo Fisher Scientific, Inc (USA)

Varian, Inc. (USA)

Analysis by Method of Preparation/Separation

Traditional

Exhibit 26: Chiral Chemicals by Traditional Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for United States and Canada

in US$ Billion (Graphical Representation Included)

Exhibit 27: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for United States and

Canada (Graphical Representation Included)

Asymmetric

Exhibit 28: Chiral Chemicals by Asymmetric Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for United States and Canada

in US$ Billion (Graphical Representation Included)

Exhibit 29: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for United States and

Canada (Graphical Representation Included)

Biological

Exhibit 30: Chiral Chemicals by Biological Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for United States and Canada

in US$ Billion (Graphical Representation Included)

Exhibit 31: Chiral Chemicals by Biological Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for United States and

Canada (Graphical Representation Included)

Other

Exhibit 32: Chiral Chemicals by Other Methods (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for United States and Canada

in US$ Billion (Graphical Representation Included)

Exhibit 33: Chiral Chemicals by Other Methods (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for United States and

Canada (Graphical Representation Included)

Analysis by Application

Pharmaceutical

Exhibit 34: Chiral Chemicals by Application in Pharmaceuticals (2005-2012) - Global

Market Analysis (Current & Future) by Geographic Region for United States and

Canada in US$ Billion (Graphical Representation Included)

Exhibit 35: Chiral Chemicals by Application in Pharmaceuticals (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region

for United States and Canada (Graphical Representation Included)

Agrochemical

Exhibit 36: Chiral Chemicals by Application in Agrochemicals (2005-2012) - Global Market

Analysis (Current & Future) by Geographic Region for United States and

Canada in US$ Billion (Graphical Representation Included)

Exhibit 37: Chiral Chemicals by Application in Agrochemicals (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region

for United States and Canada (Graphical Representation Included)

Flavors /Fragrances

Exhibit 38: Chiral Chemicals by Application in Flavors/Fragrances (2005-2012) -

Global Market Analysis (Current & Future) by Geographic Region

for United States and Canada in US$ Billion (Graphical Representation Included)

Exhibit 39: Chiral Chemicals by Application in Flavors/Fragrances (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region

for United States and Canada (Graphical Representation Included)

Other

Exhibit 40: Chiral Chemicals by Application in Other (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for United States and

Canada US$ Billion (Graphical Representation Included)

Exhibit 41: Chiral Chemicals by Application in Other (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for United States and

Canada (Graphical Representation Included)

Europe

Exhibit 42: Chiral Chemicals (2005-2012) - European Analysis (Current & Future)

in US$ Billion (Graphical Representation Included)

Major Companies in Europe

Avecia Biologics Limited (UK)

BASF Aktiengesellschaft (Germany)

Clariant AG (Switzerland)

Groupe Novasep (France)

Johnson Matthey plc (UK)

Lonza Group AG (Switzerland)

Rhodia, Inc. (France)

Solvias AG (Switzerland)

Analysis by Method of Preparation/Separation

Traditional

Exhibit 43: Chiral Chemicals by Traditional Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Germany, United Kingdom, France,

Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included)

Exhibit 44: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Germany,

United Kingdom, France, Switzerland and Rest of Europe

Asymmetric

Exhibit 45: Chiral Chemicals by Asymmetric Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Germany, United Kingdom, France,

Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included)

Exhibit 46: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Germany,

United Kingdom, France, Switzerland and Rest of Europe

Biological

Exhibit 47: Chiral Chemicals by Biological Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Germany, United Kingdom, France,

Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included)

Exhibit 48: Chiral Chemicals by Biological Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Germany, United Kingdom,

France, Switzerland and Rest of Europe

Other

Exhibit 49: Chiral Chemicals by Other Methods (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Germany, United Kingdom, France,

Switzerland and Rest of Europe in US$ Million (Graphical Representation Included)

Exhibit 50: Chiral Chemicals by Other Methods (2006, 2009 and 2012) - Percentage Breakdown

of Global Market Value by Geographic Region for Germany, United Kingdom, France,

Switzerland and Rest of Europe

Analysis by Application

Pharmaceutical

Exhibit 51: Chiral Chemicals by Application in Pharmaceuticals (2005-2012) - Global Market

Analysis (Current & Future) by Geographic Region for Germany, United Kingdom,

France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included)

Exhibit 52: Chiral Chemicals by Application in Pharmaceuticals (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region for Germany,

United Kingdom, France, Switzerland and Rest of Europe

Agrochemical

Exhibit 53: Chiral Chemicals by Application in Agrochemicals (2005-2012) - Global Market

Analysis (Current & Future) by Geographic Region for Germany, United Kingdom, France,

Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included)

Exhibit 54: Chiral Chemicals by Application in Agrochemicals (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Germany,

United Kingdom, France, Switzerland and Rest of Europe

Flavors /Fragrances

Exhibit 55: Chiral Chemicals by Application in Flavors/Fragrances (2005-2012) - Global

Market Analysis (Current & Future) by Geographic Region for Germany, United Kingdom,

France, Switzerland and Rest of Europe in US$ Million(Graphical Representation Included)

Exhibit 56: Chiral Chemicals by Application in Flavors/Fragrances (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region for Germany,

United Kingdom, France, Switzerland and Rest of Europe

Other

Exhibit 57: Chiral Chemicals by Application in Other (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Germany, United Kingdom, France,

Switzerland and Rest of Europe in US$ Million (Graphical Representation Included)

Exhibit 58: Chiral Chemicals by Application in Other (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Germany, United Kingdom,

France, Switzerland and Rest of Europe

Asia-Pacific

Exhibit 59: Chiral Chemicals (2005-2012) - ^Asia-Pacific Market Analysis (Current & Future)

in US$ Billion (Graphical Representation Included)

Major Companies in Asia-Pacific

Anhui Biochem United Pharmaceutical Co., Ltd. (China)

Huaxing Chem, Inc. (China)

Kingnord (China)

Pearce Pharmaceuticals (Australia)

Shanghai Hanhong Chemical Co., Ltd. (China)

SK Corporation (Korea)

Suven Life Sciences Limited (India)

Suzhou ChonTech PharmaChem Technology Co., Ltd. (China)

Analysis by Method of Preparation/Separation

Traditional

Exhibit 60: Chiral Chemicals by Traditional Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Australia, China, India and

Rest of Asia-Pacific in US$ Billion (Graphical Representation Included)

Exhibit 61: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Australia, China,

India and Rest of Asia-Pacific

Asymmetric

Exhibit 62: Chiral Chemicals by Asymmetric Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Australia, China, India and

Rest of Asia-Pacific in US$ Billion (Graphical Representation Included)

Exhibit 63: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Australia, China, India and

Rest of Asia-Pacific

Biological

Exhibit 64: Chiral Chemicals by Biological Method (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Australia, China, India and

Rest of Asia-Pacific in US$ Million (Graphical Representation Included)

Exhibit 65: Chiral Chemicals by Biological Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Australia, China,

India and Rest of Asia-Pacific

Other

Exhibit 66: Chiral Chemicals by Other Methods (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Australia, China, India and Rest of Asia-Pacific in US$ Million (Graphical Representation Included)

Exhibit 67: Chiral Chemicals by Other Methods (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Australia, China,

India and Rest of Asia-Pacific

Analysis by Application

Pharmaceutical

Exhibit 68: Chiral Chemicals by Application in Pharmaceuticals (2005-2012) - Global

Market Analysis (Current & Future) by Geographic Region for Australia, China,

India and Rest of Asia-Pacific in US$ Billion (Graphical Representation Included)

Exhibit 69: Chiral Chemicals by Application in Pharmaceuticals (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region for Australia,

China, India and Rest of Asia-Pacific

Agrochemical

Exhibit 70: Chiral Chemicals by Application in Agrochemicals (2005-2012) - Global Market

Analysis (Current & Future) by Geographic Region for Australia, China, India and

Rest of Asia-Pacific in US$ Million (Graphical Representation Included)

Exhibit 71: Chiral Chemicals by Application in Agrochemicals (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region for Australia,

China, India and Rest of Asia-Pacific

Flavors /Fragrances

Exhibit 72: Chiral Chemicals by Application in Flavors/Fragrances (2005-2012) - Global

Market Analysis (Current & Future) by Geographic Region for Australia, China, India and

Rest of Asia-Pacific in US$ Million (Graphical Representation Included)

Exhibit 73: Chiral Chemicals by Application in Flavors/Fragrances (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value by Geographic Region for Australia,

China, India and Rest of Asia-Pacific

Other

Exhibit 74: Chiral Chemicals by Application in Other (2005-2012) - Global Market Analysis

(Current & Future) by Geographic Region for Australia, China, India and Rest of

Asia-Pacific US$ Million (Graphical Representation Included)

Exhibit 75: Chiral Chemicals by Application in Other (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value by Geographic Region for Australia, China, India and

Rest of Asia-Pacific

Japan

Exhibit 76: Chiral Chemicals (2005-2012) -Japanese Market Analysis (Current & Future)

in US$ Billion (Graphical Representation Included)

Major Companies in Japan

Daicel Chemical Industries Ltd. (Japan)

Rest of World

Exhibit 77: Chiral Chemicals (2005-2012) - Rest of World Market Analysis (Current & Future)

in US$ Billion (Graphical Representation Included)

III. PRODUCT TECHNOLOGY/RESEARCH

1. Introduction

Definition and Overview of Chiralty

Concept of Chiral Technology

Prominent Prinicliples Governing Chiral Technology

Typing the Chirality

The Process of Axial Chirality

The Technique of Planar Chirality

The Technique of Cryptochirality

Definition and Overview of Isomerism

Types of Isomers

Structural Isomers

Nuclear or Chain Isomerism

Position Isomerism or Skeleton Isomerism.

Functional Group Isomerism

Stereo Isomerism

Geometric Isomerism

Optical Isomerism

Tautomerism

Other Varieties of Isomers

Anomers

Rotamers and Conformers

Configurational Isomers

Epimers

Meso-isomer (Achiral molecules)

Enantiomer

Diastereomer

Cis-Trans and E-Z Isomerism

Conformational Isomerism

Keto-Enol Tautomerism

Chiral Chemicals Growth Trends - Global Markets

Exhibit 78: Global Market for Chiral Chemicals: Geographic Regions (Japan, Asia-Pacific,

Europe, Rest of World and North America) Ranked by Projected CAGR

for 2005 through 2012 (Graphical Representation Included)

Chiral Synthesis

Chiral Separation

Importance of Chiral Separation

2. Segmentation of Chiral Chemicals

Segmentation by Method of Preparation/Separation

Growth Trends - Global Market for Chiral Chemicals by Method of Preparation/Separation

Exhibit 79: Global Market for Chiral Chemicals by Method (Biological,

Asymmetric, Traditional and Other) Ranked by Projected CAGR for

2005 through 2012 (Graphical Representation Included)

Traditional Method

Growth Trends - Global Market for Chiral Chemicals by Traditional Method

Exhibit 80: Global Market for Chiral Chemicals by Traditional Method: Geographic Regions

(Japan, Asia-Pacific, Europe, Rest of World and North America) Ranked by projected

CAGR for 2005 through 2012 (Graphical Representation Included)

Traditional Methods of Chiral Preparation/Separation

Crystallization

Chromatographic Resolution

Chiral Pool Synthesis

Various Chiral Separation Methods

Diastereomeric Crystallisation

Methods Preferred During Crystallisation

Diastereomeric Derivative Method

Increment and Custom Purifications

Supercritical Fluid Chromatography

High Performance Liquid Chromatography

Continous Chromatography

Crystallisation Solid-Liquid Separation Technique

Process

Crystall ization in nature

Artificial method

Production of crystal from the perspective of material industry

Purification

Thermodynamic aspect

Resolution

Kinetic resolution

Enzymatic resolution

Chromatographic Separation Technique

Introduction

Process of Chiral Chromatography

Ion Pair additives

Inclusion complexes

Ligand exchange and protein interactions

Pirkle Chiral Stationary Phases

Chromatographic Techniques

Column Chromatography

Planar Chromatography

Paper Chromatography

Thin layer Chromatography

Techniques by Physical State of Mobile Phase

Gas Chromatography

Liquid Chromatography

Supercritical fluid Chromatography

Techniques by Separation Mechanism

Ion Exchange Chromatography

Size Exclusion Chromatography

Affinity Chromatography

Stationary Phases

Chiral Effinity by Proteins

Serum Albumin

Al-acid Glycoprotein

Ovomucoid and A-Chymotrypsin

Biomedical Applications of Chiral Liquid Chromatography

Liquid Chromatographic Chiral Stationary Phases in Pharmaceutical Analysis

The Separation of Enantiomeric Sugars by Chromatographic Methods

Preparation of Pure Enantiomers using Enantioselective Liquid Chromatography - a Practical

Method of Preparation of Pure Atenolol Enantiomers

Application of Thin-Layer Chromatography in Enantiomeric Chiral Analysis

Selection of High-Performance Liquid Chromatographic Methods in Pharmaceutical Analysis

Pharmaceutical Analysis Comprising Well Performing Liquid Chromatography

The Replicated Mobile Bed

Industrial Size Simulated Moving Bed Process

Chiral Liquid Chromatography with Replicated Mobile Columns Technique

Scope of Chromatography

Procedural Divisions in Chiral Technology

Vascular Electrophoresis

Steps in Capillary Electrophoresis

Appliance

Identification

Methods of Partition

Effectiveness and Solution

Other Partition Procedures

Electromigration Partition Procedures

Course of Partition

Partition in Microflows

Smaller Molecules Passage Certainity

Asymmetric Method

Growth Trends - Global Market for Chiral Chemicals by Asymmetric Method

Exhibit 81: Global Market for Chiral Chemicals by Asymmetric Method: Geographic Regions

(Japan, Asia-Pacific, Europe, Rest of World and North America) Ranked by

Projected CAGR for 2005 through 2012 (Graphical Representation Included)

Asymmetric Methods of Synthesizing Chiral Compounds

Asymmetric Synthesis

Absolute Asymmetric Synthesis

Asymmetric Catalysis

Chiral Organocatalysis

Bio-catalysis

Asymmetric Autocatalysis

Asymmetric Hydrogenation

Asymmetric Catalytic Oxidation

Jacobsen epoxidation

Sharpless epoxidation of allyl alcohols

Sharpless asymmetric dihydroxylation of alkenes

Sharpless oxyamination

Shi epoxidation of alkenes

Asymmetric Catalytic Reduction

Biological Method

Growth Trends - Global Market for Chiral Chemicals by Biological Method

Exhibit 82: Global Market for Chiral Chemicals by Biological Method: Geographic Regions

(Asia- Pacific, Japan, Europe, North America and Rest of World) Ranked by

Projected CAGR for 2005 through 2012 (Graphical Representation Included)

Biological Techniques

Kinetic Resolution

Dynamic Kinetic Resolution

Mutual and Parallel Kinetic Resolution

Bio-catalysis

Organocatalysis

Bio-catalysis and Organocatalysis

Selectivity of Enzymes

Chemoselectivity:

Regioselectivity and Diastereoselectivity:

Enantioselectivity:

Other Methods

Growth Trends - Global Market for Chiral Chemicals by Other Methods

Exhibit 83: Global Market for Chiral Chemicals by Other Methods: Geographic Regions

(Japan, Europe, Asia-Pacific, North America and Rest of World) Ranked by Projected

CAGR for 2005 through 2012 (Graphical Representation Included)

Chiral Genesis Procedures

RetroGenesis Study

Strategies to be Followed in RetroGenesis Study

Operational Strategies

Stereochemical Strategies

Structure-Goal Strategies

Transform-based Strategies

Topological Strategies

Added Features in Chiral Genesis

Irregular Orientation

Cram's guideline on Irregular Orientation

Felkin guideline

Preserved Chirality

Chiral Resolution

Chiral Auxiliary

Capillary Electrophoresis in Chiral Analysis

Benefits of Capillary Electrophoresis Methods for Impurity Analysis

Data Integrity

Applications of Chiral Capillary Electrophoresis

Chemoenzymatic Synthesis

Resolution of Chiral Drugs

Chiral Stationary Phase

Indirect Drug Analysis

Direct Drug Analysis

Segmentation by Application

Growth Trends - Global Market for Chiral Chemicals by Application

Exhibit 84: Global Market for Chiral Chemicals by Application (Agrochemical,

Flavors/Fragrances, Other and Pharmaceutical) Ranked by Projected CAGR

for 2005through 2012 (Graphical Representation Included)

Pharmaceutical

Growth Trends - Global Market for Chiral Chemicals in Pharmaceutical

Exhibit 85: Global Market for Chiral Chemicals by Application in Pharmaceuticals: Geographic

Regions (Japan, Asia-Pacific, Europe, Rest of World and North America) Ranked

by Projected CAGR for 2005 through 2012 (Graphical Representation Included)

Chiral Technology and its use in the Pharmaceutical Industry

Chiral Compounds

Chirality in Pharmacology

Chiral Drugs

Excavations in Drug Chirality

Chiral discrimination and Enantioselective Analysis of Drugs

The Chiral Switch Drugs

Single-isomer Drugs

Enantiomeric Medicines

Application of Enantiomeric Separations in Pharmaceutical Analysis Using Chiral Elements

Liquid Chromatography-Enabled Enantiomeric Resolution of Medicinal Compounds.

Enantiopure Prescription

Enantiomerically Pure Nucleosides’ Synthesis and Antiviral Activities

Chiral Intermediates’ Application in the Pharmaceutical Industry

Chiral Alteration

Chiral Specialty Transitional Chemical:

Chiral Supplementary

Studies on DNA Binding with Novel Copper Compounds Comprising Tryptophan as

Chiral Supplementary

Cisplatin-resistant Tumor Cells of Apoptosis Induced by New Trans-platinum Medicines with

Phosphines and Amines as Carrier Ligands

Exhibit 86: Major Drugs, Companies and Sales in the Chiral Pharmaceutical Industry

Agrochemical

Growth Trends - Global Market for Chiral Chemicals in Agrochemical

Exhibit 87: Global Market for Chiral Chemicals by Application in Agrochemical:

Geographic Regions (Japan, Asia-Pacific, Europe, Rest of World and North America)

Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included)

Chiral Technology in Agrochemicals

Introduction

Pesticides

Pesticides and its Role in Pest Control - An Important Aspect of Agriculture

Enantiomeric Enrichment Profiles of Chiral Pesticides in the Environment

Understanding the Function of Constant Enantiomer Fraction

Various Environmental Applications of Chiral High-Performance Liquid Chromatography

Technique (HPLC)

Nature and Behavior of Pesticides in the Environment

Organochlorine Pesticides

Enantiomeric Separations of Neutral Organophosphorus Pesticides

Enantiomeric Separation of Chiral Pesticides by High Performance

Liquid Chromatography on Cellulose

Enantiomeric Separation of Several Antimycotic Azole Drugs using Supercritical Fluid

Chromatography

Enantiomeric Resolution of Chiral Pesticides by High-Performance Liquid Chromatography

Direct Enantiomeric Resolutions of Chiral Triazole Pesticides by High-Performance

Liquid Chromatography

Stereo- and Enantioselective Determination of Pesticides in Soil by using Achiral and

Chiral Liquid Chromatography in Combination with Matrix Solid-phase Dispersion

Chiral Separations of Pesticide Enantiomers by High-Performance Liquid Chromatography

using Cellulose Triphenylcarbamate Chiral Stationary Phase

Enantiomeric Enrichment of Chiral Pesticides in the Environment

Herbicides

Capillary Electrophoresis of Herbicides

Enantiomeric Separation of Herbicides Using Chiral HPLC

Responses of Enantioselective Characteristics to Temperature Variations

Absolute Configurations of Chiral Herbicides

Salt Dependence on Vancomycin-Herbicide Enantiomer Binding

Enantioselective Effects of Optically Active Herbicidal Activity

Enantiomeric Separation of Drugs and Herbicides on Stationary Phase

Fungicides

Harvest Safeguard

Fungal Progress Phase

Genomic in the Era Ahead

Conflict Invoked Reactions in Fungicides Elements

Mechanism in Fungicide

Bioaccretion and Biomodifications in Chiral Fungicides

Straightforward Chiral Isolations of Fungicide Enantiomers

Stereoselective Deprivation of Fungicide

Exhibit 88: Major Chiral Agrochemicals, Uses, Mode of Action, Toxicity,

Major Products and Major Companies

Exhibit 89: Chiral Agrochemicals (2005-2012) - Global Market (Current and Future)

for Insecticides, Fungicides, herbicides and Other

in US$ Billion (Graphical Representation Included)

Flavors/Fragrances

Growth Trends - Global Market for Chiral Chemicals in Flavors/Fragrances

Exhibit 90: Global Market for Chiral Chemicals by Application in Flavors/Fragrances:

Geographic Regions (Japan, Asia-Pacific, Europe, Rest of World and North America)

Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included)

Chiral Technology in Savors and Aromas

Savor and Aroma Volatiles

Savors and Aromas Alcoholic Beverages

Savors and Aromas Containing Essential Oil

Enantiomeric Ratios of Volatile Constituents in Essential Oils

Chiral Divided-Chain Fatty Acids

Glucosides as Restricted -Emitting Flavors

Impact of Chiral Aromas

Study of Chiral Segregation

Chromatographic Procedures

Resolution Isolation

Other

Growth Trends - Global Market for Chiral Chemicals in Other Applicaion

Exhibit 91: Global Market for Chiral Chemicals by Application in Other: Geographic

Regions (Japan, Asia-Pacific, Europe, Rest of World and North America) Ranked

by Projected CAGR for 2005 through 2012 (Graphical Representation Included)

Polymers

Biopolymers, Analytical Techniques

Chiral Polymer Catalysts in Preparative Organic Chemistry

Chiral Recognition Applications of Molecularly Imprinted Polymers

Synthesis of Optically Active P-Chiral and Optically Inactive Oligophosphines

Synthesis of Coordination Polymers Bipyridazine

Enantioselective Absorption of Chirally Doped Liquid Crystalline Networks

Polymeric Alkenoxy Amino Acid Surfactants

Enantioselective Synthesis of Binaphthyl Polymers using Chiral Asymmetric

Phenolic Coupling Catalysts

Chiral Intermediates

Amino Acids

Propionic Acid

Glycidol

Preparation of Chiral Intermediates

Biocatalysts and their Applications

Catalysts

Biocatalysts

Enantioselective Enzyme

Enzymes in Chiral Synthesis

Applications of Biocatalysts

Chemical Industry

Medical Field

Diabetes

Phenylketonuria [PKU]

Gaucher’s Disease

Heart Attack

Acute Childhood Leukemia

Cystic Fibrosis

Biocatalysts Employed in Drug Discovery

Bacterial Enzymes

Organometallic Catalysts

Peptide Catalysts

Chiral Ruthenium Catalysts

Enzyme Cofactors

Chirality in Veterinary Care

Veterinary Chiral Drugs

Use of Enantiomers in Veterinary Care

Chiral Drugs Used In Domestic Animals

The Action of Vedaprofen and its Enantiomers

Properties of Vedaprofen in an Equine

Pharmacokinetics and Dynamics of Ketoprofen in Horse

Role of Racemism in Active Drug Development in Cats

Pharmacokinetics and Pharmacodynamics of Ketoprofen in Calves

Enantiospecific Properties of Ketoprofen in Sheep

Behavior of Enantiomers in Male and Female Sheep

Chiral Technology in Therapeutics

Use of Nucleoside Antiretroviral Agents for HIV Treatment

Chiral Intermediates Useful in the Synthesis of HIV Protease Inhibitors

Chiral Liquid Chromatography for Diastereomeric Resolution of Antiviral Nucleotide

Amidate Pro-Drugs

Chiral Technology for Anaesthetics

The Commercial Preparation of Levorotatory Isomer

Anaesthesia Stereoisomers

Chiral Capillary Electrophoresis System Benefits

L-Isomer Clinical Applications

Pharmacokinetics

Pharmacodynamics

Chiral Technology for Hematopoietic Disorders

Chiral in Antibodies

Chiral Technology for Enantiomers Separation via Stereoselective Antibodies

Chiral Surfaces Identification by Antibody

Antibody Catalysis Studies

Hormones

Stereo Selective Synthesis of Juvenile Hormone for Stoichiometric Introduction

of Tritium Atoms

Psychiatric

Chirality Technologies and Drugs used in Psychiatry

Diabetes

Phenomenon of Chiral Mutagenesis of Insulin

Solution Structure of Human Proinsulin C-Peptide for Biosynthesis of Insulin

Calcium Antagonist Racemic Mixture in the Treatment of Hypertension

Chiral Ketone Intermediates for Flavopiridol and Analogs

Synthesis and Antiviral Activities

Dermal

Application of Chiral Technology for Skin Care Product Manufacture

Chirally Correct Ingredients for Effective Skin Care

Cardiovascular

Application of Chiral Technology in Cardiovascular Research

Effect of Enantioselective Actions on Coronary Vascular Resistance

Stereo Selective Chromatography of Drugs for Application in Treatment of

Cardiovascular Disorders

Enantiomeric Resolution of Cardiovascular Agents for

Better Quality Control of Drugs

Application of Beta-Adrenergic Blockers to Heal Cardio Vascular Disorders

Diuretics

Application of Liquid Chromatography for Separation of Stereoisomers of Diuretics

Establishing the Structure of Diuretic-Glutathione Conjugate

Enantiomers of Benzothiadiazine by the Direct Chromatographic Resolution of

the Racemic Drugs

Carcinoma

Synthesis, Molecular Recognition, and Anticancer Activity of Chiral Compounds

Chromatographic Separations and Circular Dichroism using Chiral Stationery Phases

Production of 13-Hydroxyoctadecadienoic Acids to Monitor Progression

of Prostate Cancer

Stereo Selectivity of Esterases for Development of Prodrugs for Treatment of Cancer

Preparation of a Chiral Matrix to Analyze Effects of Unnatural Diastereomer

Analysis of Lipoxygenase Products in Human Saliva using Gas Chromatography

Metabolic Chiral Inversion of Arylpropionates for Application in Vivo Models

Anticancer Activity of Beta-l-Dioxolane-Cytidine Containing Unnatural Configuration

Chiral Analysis Methods

Circular Dichroism

Polarized Light

Derivation of Ellipticity

Application of Biological Molecules

Simulated Moving Bed

Construction

Advantages

Applications

X-Ray Crystallography

Scattering Techniques

X-ray Scattering Techniques

Elastic vs. Inelastic Scattering

Other Types of X-ray Scattering

Electron and Neutron Diffraction

Advantages of a Crystal

Methods

Crystallization

Data Collection

Mounting the Crystal

X-Ray Sources

Recording the Reflections

Data Analysis

Crystal Symmetry, Unit Cell, and Image Scaling

Initial Phasing

Model Building and Phase Refinement

Deposition of the Structure

High Performance Liquid Chromatography

Types of HPLC

Normal Phase Chromatography

Reversed Phase chromatography

Size Exclusion Chromatography

Ion-exchange Chromatography

Bio-affinity Chromatography

Gas-Liquid Chromatography

Methods

Carrier gas selection and flow rates

Inlet Types and Flow Rates

Sample Size and Injection Technique

Column selection

Data Reduction and Analysis

1) Qualitative Analysis

2) Quantitative Analysis

Application

Nuclear Magnetic Resonance Spectroscopy

Types of Nuclear Magnetic Resonance Spectroscopy

Continuous Wave Spectroscopy

Fourier Spectroscopy

Multi-Dimensional

Solids

Sensitivity

Applications

Medicine

Chemistry

Non-Destructive Testing

Data Acquisition in the Petroleum Industry

Polarimetry

Measuring Optical Rotation

Applications

1) Quality and Process Control Applications

2) Pharmaceutical Industry

3) Flavor, Fragrance, and Essential Oil Industry

4) Food Industry

5) Carbohydrates

6) Chemical Industry

IV. MARKET DYNAMICS

1. Market Overview

Global Market Analysis

Exhibit 92: Chiral Chemicals (2005-2012) - Global Market Analysis (Current & Future) by

Geographic Region for North America, Europe, Asia-Pacific, Japan and

Rest of World in US$ Billion (Graphical Representation Included)

Exhibit 93: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Global Market Value by Geographic Region for North America, Europe, Asia-Pacific,

Japan and Rest of World (Graphical Representation Included)

Analysis by Method of Preparation/Separation

Exhibit 94: Chiral Chemicals (2005-2012) - Global Market Analysis (Current and Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Billion (Graphical Representation Included)

Exhibit 95: - Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Global Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 96: Chiral Chemicals by Traditional Method (2005-2012) - Global Market Analysis

(Current and Future) for Diastereomeric Crystallization, Chromatography and

Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 97: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Global Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 98: Chiral Chemicals by Asymmetric Method (2005-2012) - Global

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Billion (Graphical Representation Included)

Exhibit 99: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 100: Chiral Chemicals by Biological Method (2005-2012) - Global

Market Analysis (Current and Future) for Bio-catalysis and

Kinetic Resolution in US$ Billion (Graphical Representation Included)

Exhibit 101: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Global Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 102: Chiral Chemicals (2005-2012) - Global Market Analysis (Current and Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 103: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Global Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other

2. Market Trends

The Emergence of Chiral Drugs

Uses of Chiral Technology in Biotechnology

3. Major Global Companies In Chiral Chemicals Industry

Albemarle Corporation (USA)

Alps Pharmaceutical Ind. Co., Ltd. (Japan)

Altus Pharmaceuticals, Inc. (USA)

Anhui Biochem United Pharmaceutical Co., Ltd. (China)

Avecia Biologics Limited. (UK)

BASF Aktiengesellschaft (Germany)

Beckman Coulter, Inc. (USA)

Boulder Scientific Company (USA)

Cambrex Corporation (USA)

Chiral Quest, Inc. (USA)

Chiral Technologies, Inc. (USA)

Clariant AG (Switzerland)

Daicel Chemical Industries Ltd. (Japan)

DavosPharma (USA)

Digital Specialty Chemicals (Canada)

Dow Chemical Company (USA)

Genencor (USA)

Genzyme Corporation (USA)

Groupe Novasep (France)

Huaxing Chem, Inc (China)

JASCO, Inc. (USA)

Johnson Matthey plc (UK)

Kingnord (China)

Lonza Group AG (Switzerland)

Maxygen (USA)

PDR-Chiral, Inc. (USA)

Pearce Pharmaceuticals (Australia)

PerkinElmer, Inc. (USA)

Phenomenex, Inc. (USA)

Regis Technologies, Inc. (USA)

Rhodia, Inc. (France)

Rudolph Instruments, Inc. (USA)

SEDERE, Inc. (USA)

Shanghai Hanhong Chemical Co., Ltd. (China)

SK Corporation (Korea)

Solvias AG (SWITZERLAND)

Strem Chemicals, Inc. (USA)

Suven Life Sciences Limited (India)

Suzhou ChonTech PharmaChem Technology Co., Ltd. (China)

Synthetech, Inc. (USA)

Synthon Chiragenics Corporation (USA)

Thermo Fisher Scientific, Inc (USA)

Varian, Inc. (USA)

4. Major Activities in Chiral Technology Industry

JASCO Signs Partnership Agreement with Restek…

Thermo Fisher Scientific Enters into Alliance with Phytronix for Providing Advanced

LDTD Technology for Rapid LC/MS Analyses…

Shire Human Grants Marketing License to Genzyme for Elaprase®

Waters and Thar Extend Collaboration for Greener Separations

Sircuit® Cosmeceuticals Signs Partnership Agreement with Inskin Cosmedics Group

Groupe Novasep to Buy PharmaChem Technologies to form a Leading Supplier for

the Life Science Industries

ZaCh Systems Purchases Fine Chemicals Unit

Proxycs Signs Partnership Agreement with Novasep Process

Codexis Purchases BioCatalytics: Merger Creates a new Worldwide Leader in the Design,

Synthesis and Use of Biocatalysts

VioQuest Pharmaceuticals Strengthens Balance Sheet through Sale of

Chiral Quest Subsidiary and Completion of Private Placement

CNRS and Rhodia Extend Their Long-Standing Partnership

Strategic Alliance between Daicel Chemical Industries and Groupe Novasep for

Chiral Separation

Lonza Plans New Plant for Large-scale Production of Highly Potent APIs

DowpharmaSM Signs License Agreement with VGX Pharmaceuticals for Production

of Viral Proteins to Treat Cancer

Rahu Catalytics Strategic Alliance with Avantium Technologies

SAFC Completes Construction of Two New Protein Purification Facilities

Codexis Signs Technology Agreement with Merck

Almac forms Strategic Alliance with BioCatalytics

Nicholas Piramal Targets European Market with New Innovation Centre

Albermarle Corp., Acquires DSM Facility

Sigma-Aldrich Buys Astec

Suven Signs Collaborative Agreement with Eli Lilly

Chiral Catalysis Technology License Granted to Solvias

Clariant Sells Pharmaceutical Fine Chemicals to TowerBrook Capital Partners

Rhodia Sells its Pharmaceutical Custom Synthesis Business to Shasun Chemicals & Drugs

Solvias Gets Exclusive License from Yale University for Highly Efficient

C N-Coupling Technology

Regis Technologies to Expand Chiral Separation Services with SFC

IEP Signs License Agreement with SK Energy & Chemical for Bio-Process Technology

Chiral Technologies Licenses HPLC for Chiral Drugs

Codexis Inc Purchases Julich Fine Chemicals

5. Major Product Innovations/Launches in Chiral Technology Industry

PerkinElmer Launches Novel and Effective Sample Introduction Systems for Application in

Environmental based studies…

Regis Launches RegisPack™ Polysaccharide Coated Chiral Columns…

Zebron ZB-XLB - New Low Polarity GC Columns that Provide Stable GC Analysis

For Environmental Applications

PerkinElmer Launches New Gas Chromatograph

Phenomenex Introduces New Luna® HILIC Chromatography Columns for

Analysis of Polar Metabolites

Varian Launches New Capillary Column for the Analysis of Polar Compounds using GS/MS

New Compact HPLC Column Temperature Controller Available at a Low Cost

Genecor Launches Maxaliq™ ONE for Improved Ethanol Production from Corn

CMO Daiso Acquires Chiral Synthesis Technology from Harvard

Avecia Launches New Protein Production Technology for the Manufacture of

Biopharmaceuticals

PerkinElmer Launches New GC/MS to Meet Customer Needs

Chiral Technologies Introduces CHIRALPAK® IC

JASCO Introduces New Preparative SFE/SFC System with Chiral Detection

Chirosolve Introduces Chirosolv® Kits…

JASCO Launches its New Unique P-2000 Polarimeter

Varian Introduces HPLC Columns for Use in R&D

Novasep Launches New HPLC Columns for Superior Purification

VersaMatrix Launches Versaffin™ for Customized Affinity Ligands

ENS Releases New Analytical Chiral Column for the Separation of Small Molecules

Eksigent Increases its Chromatography Column Product Line

GE Healthcare Launches New Peptide Separation System

JASCO Launches J-815 - The Most Modern Spectropolarimeter

GE Healthcare Introduces High Performance Fast Flow Products

The World’s Fastest LC System Launched by Agilent

Agilent Technologies Launches New Mass Spectrometer Product Line

ZirChrom Separations Inc. Introduces a New Class of CSPs

PerkinElmer Introduces the dotLINK Interface, Providing GC And HPLC Users

With Ethernet Connectivity

6. Regional Market Analysis

A. North America

Exhibit 104: Chiral Chemicals (2005-2012) -North American Market Analysis

(Current & Future) in US$ Billion (Graphical Representation Included)

Exhibit 105: List of Major Companies in North America

Analysis by Geographic Region

Exhibit 106: Chiral Chemicals (2005-2012) - North American Market Analysis

(Current and Future) by Geographic Region for United States and

Canada in US$ Billion (Graphical Representation Included)

Exhibit 107: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

North American Market Value by Geographic Region for

United States and Canada (Graphical Representation Included)

Analysis by Method of Preparation/Separation

Exhibit 108: Chiral Chemicals (2005-2012) - North American Market Analysis

(Current & Future) by Method for Traditional, Asymmetric, Biological and

Other in US$ Billion (Graphical Representation Included)

Exhibit 109: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

North American Market Value by Method for Traditional, Asymmetric,

Biological and Other (Graphical Representation Included)

Analysis by Traditional Method

Exhibit 110: Chiral Chemicals by Traditional Method (2005-2012) - North American

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 111: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of North American Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 112: Chiral Chemicals by Asymmetric Method (2005-2012) - North American

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Billion (Graphical Representation Included)

Exhibit 113: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of North American Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 114: Chiral Chemicals by Biological Method (2005-2012) - North American

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Billion (Graphical Representation Included)

Exhibit 115: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of North American Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 116: Chiral Chemicals (2005-2012) - North American Market Analysis (Current &

Future) by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 117: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

North American Market Value by Application for Pharmaceutical,

Agrochemical, Flavors/Fragrances and Other (Graphical Representation Included)

A1. United States

Analysis by Method of Preparation/Separation

Exhibit 118: Chiral Chemicals (2005-2012) -United States Market Analysis (Current &

Future) by Method for Traditional, Asymmetric, Biological and

Other in US$ Billion (Graphical Representation Included)

Exhibit 119: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

United States Market Value by Method for Traditional, Asymmetric,

Biological and Other

Analysis by Traditional Method

Exhibit 120: Chiral Chemicals by Traditional Method (2005-2012) - United States

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 121: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of United States Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 122: Chiral Chemicals by Asymmetric Method (2005-2012) - United States

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Billion (Graphical Representation Included)

Exhibit 123: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of United States Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 124: Chiral Chemicals by Biological Method (2005-2012) - United States

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Billion (Graphical Representation Included)

Exhibit 125: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of United States Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 126: Chiral Chemicals (2005-2012) - United States Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 127: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

United States Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

A2. Canada

Analysis by Method of Preparation/Separation

Exhibit 128: Chiral Chemicals (2005-2012) - Canadian Market Analysis (Current & Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Billion (Graphical Representation Included)

Exhibit 129: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of Canadian

Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 130: Chiral Chemicals by Traditional Method (2005-2012) - Canadian Market Analysis

(Current and Future) for Diastereomeric Crystallization, Chromatography and

Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 131: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Canadian Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 132: Chiral Chemicals by Asymmetric Method (2005-2012) - Canadian

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Billion (Graphical Representation Included)

Exhibit 133: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Canadian Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 134: Chiral Chemicals by Biological Method (2005-2012) - Canadian

Market Analysis (Current and Future) for Bio-catalysis and

Kinetic Resolution in US$ Billion (Graphical Representation Included)

Exhibit 135: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Canadian Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 136: Chiral Chemicals (2005-2012) - Canadian Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 137: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Canadian Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

B. Europe

Exhibit 138: Chiral Chemicals (2005-2012) - European Market Analysis

(Current & Future) in US$ Billion (Graphical Representation Included)

Exhibit 139: List of Major Companies in Europe

Analysis by Geographic Region

Exhibit 140: Chiral Chemicals (2005-2012) - European Market Analysis (Current & Future)

by Geographic Region for Germany, United Kingdom, France, Switzerland and

Rest of Europe in US$ Billion (Graphical Representation Included)

Exhibit 141: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

European Market Value by Geographic Region for Germany, United Kingdom,

France, Switzerland and Rest of Europe

Analysis by Method of Preparation/Separation

Exhibit 142: Chiral Chemicals (2005-2012) -European Market Analysis (Current & Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Billion (Graphical Representation Included)

Exhibit 143: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

European Market Value by Method for Traditional, Asymmetric, Biological and

Other (Graphical Representation Included)

Analysis by Traditional Method

Exhibit 144: Chiral Chemicals by Traditional Method (2005-2012) - European

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 145: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of European Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 146: Chiral Chemicals by Asymmetric Method (2005-2012) - European

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Billion (Graphical Representation Included)

Exhibit 147: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of European Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 148: Chiral Chemicals by Biological Method (2005-2012) - European

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Billion (Graphical Representation Included)

Exhibit 149: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of European Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 150: Chiral Chemicals (2005-2012) - European Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 151: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of European

Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other

B1. Germany

Analysis by Method of Preparation/Separation

Exhibit 152: Chiral Chemicals (2005-2012) - German Market Analysis (Current & Future)

by Method for Traditional, Asymmetric, Biological and

Other in US$ Billion (Graphical Representation Included)

Exhibit 153: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of German

Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 154: Chiral Chemicals by Traditional Method (2005-2012) - German

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 155: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of German Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 156: Chiral Chemicals by Asymmetric Method (2005-2012) - German

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 157: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of German Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 158: Chiral Chemicals by Biological Method (2005-2012) - German Market

Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 159: Chiral Chemicals by Biological Method (2006, 2009 and 2012) - Percentage

Breakdown of German Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 160: Chiral Chemicals (2005-2012) - German Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 161: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of German

Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

B2. United Kingdom

Analysis by Method of Preparation/Separation

Exhibit 162: Chiral Chemicals (2005-2012) - United Kingdom Market Analysis

(Current & Future) by Method for Traditional, Asymmetric, Biological and

Other in US$ Billion (Graphical Representation Included)

Exhibit 163: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

United Kingdom Market Value by Method for Traditional, Asymmetric,

Biological and Other

Analysis by Traditional Method

Exhibit 164: Chiral Chemicals by Traditional Method (2005-2012) - United Kingdom

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 165: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of the United Kingdom Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 166: Chiral Chemicals by Asymmetric Method (2005-2012) - United Kingdom

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 167: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of United Kingdom Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 168: Chiral Chemicals by Biological Method (2005-2012) - United Kingdom

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 169: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of United Kingdom Market Value for

Bio-catalysis and Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 170: Chiral Chemicals (2005-2012) - United Kingdom Market Analysis (Current &

Future) by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion

Exhibit 171: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

United Kingdom Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other

B3. France

Analysis by Method of Preparation/Separation

Exhibit 172: Chiral Chemicals (2005-2012) -French Market Analysis (Current & Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Billion (Graphical Representation Included)

Exhibit 173: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of French

Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 174: Chiral Chemicals by Traditional Method (2005-2012) - French Market Analysis

(Current and Future) for Diastereomeric Crystallization, Chromatography and

Chiral Pool in US$ Million (Graphical Representation Included)

Exhibit 175: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of French Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 176: Chiral Chemicals by Asymmetric Method (2005-2012) - French

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 177: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of French Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 178: Chiral Chemicals by Biological Method (2005-2012) - French

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 179: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of French Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 180: Chiral Chemicals (2005-2012) - French Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 181: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

French Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

B4. Switzerland

Analysis by Method of Preparation/Separation

Exhibit 182: Chiral Chemicals (2005-2012) -Swiss Market Analysis (Current & Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Million (Graphical Representation Included)

Exhibit 183: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of Swiss

Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 184: Chiral Chemicals by Traditional Method (2005-2012) - Swiss Market Analysis

(Current and Future) for Diastereomeric Crystallization, Chromatography and

Chiral Pool in US$ Million (Graphical Representation Included)

Exhibit 185: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Swiss Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 186: Chiral Chemicals by Asymmetric Method (2005-2012) - Swiss

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 187: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Swiss Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 188: Chiral Chemicals by Biological Method (2005-2012) - Swiss

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 189: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Swiss Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 190: Chiral Chemicals (2005-2012) - Swiss Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Million (Graphical Representation Included)

Exhibit 191: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Swiss Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

B5. Rest of Europe

Analysis by Method of Preparation/Separation

Exhibit 192: Chiral Chemicals (2005-2012) -Rest of Europe Market Analysis (Current &

Future) by Method for Traditional, Asymmetric, Biological and

Other in US$ Million (Graphical Representation Included)

Exhibit 193: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Rest of Europe Market Value by Method for Traditional, Asymmetric,

Biological and Other

Analysis by Traditional Method

Exhibit 194: Chiral Chemicals by Traditional Method (2005-2012) - Rest of Europe

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Million (Graphical Representation Included)

Exhibit 195: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Rest of Europe Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 196: Chiral Chemicals by Asymmetric Method (2005-2012) - Rest of Europe

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 197: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Rest of Europe Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 198: Chiral Chemicals by Biological Method (2005-2012) - Rest of Europe

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 199: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Rest of Europe Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 200: Chiral Chemicals (2005-2012) - Rest of Europe Market Analysis (Current &

Future) by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Million (Graphical Representation Included)

Exhibit 201: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Rest of Europe Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

C. Asia-Pacific

Exhibit 202: Chiral Chemicals (2005-2012) - ^Asia-Pacific Market Analysis

(Current & Future) in US$ Billion (Graphical Representation Included)

Exhibit 203: List of Major Companies in Asia-Pacific

Analysis by Geographic Region

Exhibit 204: Chiral Chemicals (2005-2012) - ^Asia-Pacific Market Analysis (Current &

Future) by Geographic Region for Australia, China, India and

Rest of Asia-Pacific in US$ Billion (Graphical Representation Included)

Exhibit 205: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

^Asia-Pacific Market Value by Geographic Region for Australia, China, India and

Rest of Asia-Pacific (Graphical Representation Included)

Analysis by Method of Preparation/Separation

Exhibit 206: Chiral Chemicals (2005-2012) -Asia-Pacific Market Analysis (Current &

Future) by Method for Traditional, Asymmetric, Biological and Other

in US$ Billion (Graphical Representation Included)

Exhibit 207: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Asia-Pacific Market Value by Method for Traditional, Asymmetric, Biological and

Other (Graphical Representation Included)

Analysis by Traditional Method

Exhibit 208: Chiral Chemicals by Traditional Method (2005-2012) - Asia-Pacific

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 209: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Asia-Pacific Market Value by Traditional for Diastereomeric Crystallization,

Chromatography and Chiral Pool (Graphical Representation Included)

Analysis by Asymmetric Method

Exhibit 210: Chiral Chemicals by Asymmetric Method (2005-2012) - Asia-Pacific

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Billion (Graphical Representation Included)

Exhibit 211: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Asia-Pacific Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 212: Chiral Chemicals by Biological Method (2005-2012) - Asia-Pacific

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 213: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Asia-Pacific Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 214: Chiral Chemicals (2005-2012) - Asia-Pacific Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 215: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Asia-Pacific Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

C1. Australia

Analysis by Method of Preparation/Separation

Exhibit 216: Chiral Chemicals (2005-2012) -Australian Market Analysis (Current &

Future) by Method for Traditional, Asymmetric, Biological and Other

in US$ Million (Graphical Representation Included)

Exhibit 217: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of Australian

Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 218: Chiral Chemicals by Traditional Method (2005-2012) - Australian

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 219: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Australian Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 220: Chiral Chemicals by Asymmetric Method (2005-2012) - Australian

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 221: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Australian Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 222: Chiral Chemicals by Biological Method (2005-2012) - Australian

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 223: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Australian Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 224: Chiral Chemicals (2005-2012) - Australian Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Million (Graphical Representation Included)

Exhibit 225: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown

of Australian Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

C2. China

Analysis by Method of Preparation/Separation

Exhibit 226: Chiral Chemicals (2005-2012) -Chinese Market Analysis (Current & Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Million (Graphical Representation Included)

Exhibit 227: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Chinese Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 228: Chiral Chemicals by Traditional Method (2005-2012) - Chinese Market Analysis

(Current and Future) for Diastereomeric Crystallization, Chromatography and

Chiral Pool in US$ Million (Graphical Representation Included)

Exhibit 229: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Chinese Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 230: Chiral Chemicals by Asymmetric Method (2005-2012) - Chinese

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 231: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Chinese Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 232: Chiral Chemicals by Biological Method (2005-2012) - Chinese

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 233: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Chinese Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 234: Chiral Chemicals (2005-2012) - Chinese Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Million (Graphical Representation Included)

Exhibit 235: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Chinese Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

C3. India

Analysis by Method of Preparation/Separation

Exhibit 236: Chiral Chemicals (2005-2012) -Indian Market Analysis (Current & Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Million (Graphical Representation Included)

Exhibit 237: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of Indian

Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 238: Chiral Chemicals by Traditional Method (2005-2012) - Indian Market Analysis

(Current and Future) for Diastereomeric Crystallization, Chromatography and

Chiral Pool in US$ Million (Graphical Representation Included)

Exhibit 239: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) -

Percentage Breakdown of Indian Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 240: Chiral Chemicals by Asymmetric Method (2005-2012) - Indian

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 241: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Indian Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 242: Chiral Chemicals by Biological Method (2005-2012) - Indian

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 243: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Indian Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 244: Chiral Chemicals (2005-2012) - Indian Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Million (Graphical Representation Included)

Exhibit 245: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown

of Indian Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

C4. Rest of Asia-Pacific

Analysis by Method of Preparation/Separation

Exhibit 246: Chiral Chemicals (2005-2012) -Rest of Asia-Pacific Market Analysis

(Current & Future) by Method for Traditional, Asymmetric, Biological and

Other in US$ Million (Graphical Representation Included)

Exhibit 247: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Rest of Asia-Pacific Market Value by Method for Traditional, Asymmetric,

Biological and Other

Analysis by Traditional Method

Exhibit 248: Chiral Chemicals by Traditional Method (2005-2012) - Rest of Asia-Pacific

Market Analysis (Current and Future) for Diastereomeric Crystallization,

Chromatography and Chiral Pool in US$ Million

Exhibit 249: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Rest of Asia-Pacific Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 250: Chiral Chemicals by Asymmetric Method (2005-2012) - Rest of Asia-Pacific

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 251: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Rest of Asia-Pacific Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 252: Chiral Chemicals by Biological Method (2005-2012) - Rest of Asia-Pacific

Market Analysis (Current and Future) for Bio-catalysis and Kinetic Resolution

in US$ Million (Graphical Representation Included)

Exhibit 253: Chiral Chemicals by Biological Method (2006, 2009 and 2012) - Percentage

Breakdown of Rest of Asia-Pacific Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 254: Chiral Chemicals (2005-2012) - Rest of Asia-Pacific Market Analysis

(Current & Future) by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other in US$ Million (Graphical Representation Included)

Exhibit 255: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Rest of Asia-Pacific Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

D. Japan

Exhibit 256: Chiral Chemicals (2005-2012) -Japanese Market Analysis (Current & Future)

in US$ Billion (Graphical Representation Included)

Exhibit 257: List of Major Companies in Japan

Analysis by Method of Preparation/Separation

Exhibit 258: Chiral Chemicals (2005-2012) -Japanese Market Analysis (Current & Future)

by Method for Traditional, Asymmetric, Biological and Other

in US$ Billion (Graphical Representation Included)

Exhibit 259: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Japanese Market Value by Method for Traditional, Asymmetric, Biological and Other

Analysis by Traditional Method

Exhibit 260: Chiral Chemicals by Traditional Method (2005-2012) - Japanese Market Analysis

(Current and Future) for Diastereomeric Crystallization, Chromatography and

Chiral Pool in US$ Billion (Graphical Representation Included)

Exhibit 261: Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Japanese Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 262: Chiral Chemicals by Asymmetric Method (2005-2012) - Japanese

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 263: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Japanese Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 264: Chiral Chemicals by Biological Method (2005-2012) - Japanese

Market Analysis (Current and Future) for Bio-catalysis and

Kinetic Resolution in US$ Million (Graphical Representation Included)

Exhibit 265: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Japanese Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 266: Chiral Chemicals (2005-2012) - Japanese Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 267: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Japanese Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

E. Rest of World

Exhibit 268: Chiral Chemicals (2005-2012) - Rest of World Market Analysis

(Current & Future) in US$ Billion (Graphical Representation Included)

Exhibit 269: List of Major Companies in Rest of World

Analysis by Method of Preparation/Separation

Exhibit 270: Chiral Chemicals (2005-2012) -Rest of World Market Analysis (Current &

Future) by Method for Traditional, Asymmetric, Biological and Other

in US$ Billion (Graphical Representation Included)

Exhibit 271: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Rest of World Market Value by Method for Traditional, Asymmetric,

Biological and Other

Analysis by Traditional Method

Exhibit 272: Chiral Chemicals by Traditional Method (2005-2012) - Rest of World Market

Analysis (Current and Future) for Diastereomeric Crystallization, Chromatography and

Chiral Pool in US$ Million (Graphical Representation Included)

Exhibit 273: - Chiral Chemicals by Traditional Method (2006, 2009 and 2012) - Percentage

Breakdown of Rest of World Market Value for Diastereomeric Crystallization,

Chromatography and Chiral Pool

Analysis by Asymmetric Method

Exhibit 274: Chiral Chemicals by Asymmetric Method (2005-2012) - Rest of World

Market Analysis (Current and Future) for Synthesis and Catalysis

in US$ Million (Graphical Representation Included)

Exhibit 275: Chiral Chemicals by Asymmetric Method (2006, 2009 and 2012) -

Percentage Breakdown of Rest of World Market Value for Synthesis and

Catalysis (Graphical Representation Included)

Analysis by Biological Method

Exhibit 276: Chiral Chemicals by Biological Method (2005-2012) - Rest of World

Market Analysis (Current and Future) for Bio-catalysis and

Kinetic Resolution in US$ Million (Graphical Representation Included)

Exhibit 277: Chiral Chemicals by Biological Method (2006, 2009 and 2012) -

Percentage Breakdown of Rest of World Market Value for Bio-catalysis and

Kinetic Resolution (Graphical Representation Included)

Analysis by Application

Exhibit 278: Chiral Chemicals (2005-2012) - Rest of World Market Analysis (Current & Future)

by Application for Pharmaceutical, Agrochemical, Flavors/Fragrances and

Other in US$ Billion (Graphical Representation Included)

Exhibit 279: Chiral Chemicals (2006, 2009 and 2012) - Percentage Breakdown of

Rest of World Market Value by Application for Pharmaceutical, Agrochemical,

Flavors/Fragrances and Other (Graphical Representation Included)

7. Industry Outlook

V. CORPORATE DIRECTORY

Abstract

This market insight report on Chiral Chemicals focuses on the different Methods and Applications of Chiral Chemicals. Various Chiral Chemical preparation and separation methods include Traditional, Asymmetric, Biological and Other. Pharmaceuticals, Agrochemicals, Flavors/Fragrances are the different Chiral Chemical applications discussed. The study provides global market analysis for preparation of Chiral Chemicals by Traditional (Diastereomeric Crystallisation, Chromatography & Chiral Pool), Asymmetric (Synthesis & Catalysis) and Biological (Bio-catalysis & Kinetic Resolution). The study includes estimates and projections for the global Chiral Chemicals market. Projections and estimates figure for geographic regions including North America, Europe, Asia-Pacific, Japan, and Rest of World. The industry is analyzed in US Dollars and includes 279 exclusive exhibits with graphical representations. A total of 358 companies are covered that are engaged in Chiral Chemical R&D, discovery, testing, and supply of products and services.

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