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Drug Delivery Systems

Published by: Freedonia Group Inc

Published: Mar. 1, 2008 - 338 Pages


Table of Contents


INTRODUCTION

I. EXECUTIVE SUMMARY

II. MARKET ENVIRONMENT

General

Macroeconomic Trends

Demographic Patterns

Health Care Trends

Health Insurance

Medical Conditions

Acute Conditions

Chronic Conditions

National Health Expenditures

Medical Providers

Outpatient Clinics

Skilled Nursing Homes

Acute Care Hospitals

Physicians

Patient Activity

Acute Care Hospital Admissions

Surgical Procedures

Outpatient Visits

Pharmaceutical Market Overview

Regulation

Research & Development

Demand Patterns & Forecasts

Therapeutic Classes

Generic Competition

Dosage Formulations

Regulatory Classifications

III. DRUG DELIVERY MATERIALS

General

Sterile & Purified Water

Synthetic Polymers

Polyethylene Glycol (PEG)

Acrylic Polymers

Carbomers

Methacrylate Copolymers

Polyethylene Oxide

Polyvinyl Alcohol

Other Synthetic Polymers

Cellulose Derivatives

Ethyl Cellulose

Hydroxypropyl Methylcellulose (HPMC)

Other Cellulose Derivatives

Minerals

Mineral Hydrocarbons

Petrolatum

Mineral Oil

Mineral Hydrocarbon Waxes

Other Minerals

Attapulgite

Calcium Carbonate

Calcium Silicate

Electrolytes

Other Drug Delivery Materials

Starch Compounds

Cyclodextrins

Dextrates

Dextrin

Maltodextrin

Sugars & Polyols

Sucrose

Sorbitol

Lactose

Mannitol

Natural Gums

All Other Drug Delivery Materials

IV. DRUG DELIVERY SYSTEMS OVERVIEW

General

Types of Drug Delivery Systems

Historical Demand Patterns

Regulation

Research & Development

US Trade

International Markets

V. ORAL DRUG DELIVERY SYSTEMS

General

Controlled-Release Formulations

Technologies

Coated Systems

Diffusion Systems

Reservoir Systems

Chewable Tablets

Orally Disintegrating Tablets

Nanoparticulate Formulations

Ethical Pharmaceuticals

Over-the-Counter Drugs

Transmucosal Formulations

VI. PARENTERAL DRUG DELIVERY SYSTEMS

General

Therapeutic Monoclonal Antibodies

Technology

Anti-Cancer Agents

Other Therapeutic Monoclonal Antibodies

Products in Development

Prefilled Syringes

Applications

Injectors

Cartridges & Insulin Pens

Encapsulated Systems

Polymer-Protected Systems

PEGylated Formulations

Other Polymer-Protected Pharmaceuticals

Liposomes

Developmental Activities

Premixed IV Solutions

Mini-Bags

Bag/Vial Infusion Systems

Applications

VII. INHALATION, TRANSDERMAL & IMPLANTABLE DRUG DELIVERY SYSTEMS

General

Inhalation Drug Delivery Systems

Dry Powder Formulations

Devices & Technologies

Applications

Metered Dose Formulations

Devices & Technologies

Applications

Transdermal Drug Delivery Systems

Products & Technologies

Developers & Suppliers

Applications

Implantable Drug Delivery Systems

Drug-Eluting Stents

Drug Inserts

Brachytherapy

VIII. APPLICATIONS

General

Central Nervous System Agents

Respiratory Agents

Hormones & Related Agents

Gastrointestinal Agents

Cardiovascular Agents

Anti-Infective Agents

Nutritional Agents

Biologicals

Genito-Urinary Agents

Other Therapies

IX. INDUSTRY STRUCTURE

General

Developmental Revenues

Market Share

Competitive Strategies

Mergers & Acquisitions

Licensing & Related Agreements

Marketing & Distribution

Manufacturing

Company Profiles

Alkermes Incorporated

AptarGroup Incorporated

Aradigm Corporation

Associated British Foods plc

Aveva Drug Delivery Systems, see Nitto Denko

Baxter International Incorporated

Becton, Dickinson and Company

Bespak, see Consort Medical

Cardinal Health Pharmaceutical Technologies and Services, see Catalent Pharma Solutions

Catalent Pharma Solutions Incorporated

Cephalon Incorporated

CIMA LABS, see Cephalon

Consort Medical plc

Corium International Incorporated

CyDex Pharmaceuticals Incorporated

Depomed Incorporated

Dow Corning Corporation

DURECT Corporation

Elan Corporation plc

Emisphere Technologies Incorporated

Encore Medical, see ReAble Therapeutics

Eurand NV

Flamel Technologies SA

Genzyme Corporation

Hospira Incorporated

IOMED, see ReAble Therapeutics

Johnson & Johnson

Nastech Pharmaceutical Company Incorporated

Nektar Therapeutics

Nitto Denko Corporation

NOF Corporation

Penwest Pharmaceuticals Company

ReAble Therapeutics Incorporated

Safety Syringes Incorporated

SPI Pharma, see Associated British Foods

StrataGent Life Sciences, see Corium International

3M Company

Valeritas LLC

Valois SAS, see AptarGroup

Other Companies Mentioned in Study

LIST OF TABLES

SECTION I -- EXECUTIVE SUMMARY

Summary Table

SECTION II -- MARKET ENVIRONMENT

1 Macroeconomic Indicators

2 Population by Age Group

3 Acute Conditions by Type

4 Chronic Conditions by Type

5 National Health Expenditures by Type

6 Medical Providers by Type

7 Patient Activity by Type

8 Pharmaceutical Demand by Therapeutic Class

9 Pharmaceutical Demand by Commercial Status

10 Pharmaceutical Demand by Dosage Formulation

11 Pharmaceutical Demand by Regulatory Classification

SECTION III -- DRUG DELIVERY MATERIALS

1 Drug Delivery Material Demand by Type

2 Sterile & Purified Water Demand in Drug Delivery

3 Synthetic Polymer Demand in Drug Delivery

4 Cellulose Derivative Demand in Drug Delivery

5 Mineral Demand in Drug Delivery

6 Other Material Demand in Drug Delivery

SECTION IV -- DRUG DELIVERY SYSTEMS OVERVIEW

1 Drug Delivery System Demand by Dosage Formulation

2 Drug Delivery System Demand, 1997-2007

3 US Trade in Drug Delivery Systems

4 World Drug Delivery System Demand by Region

SECTION V -- ORAL DRUG DELIVERY SYSTEMS

1 Oral Drug Delivery System Demand by Type

2 Oral Controlled-Release Drug Delivery System Demand

3 Coated Controlled-Release Drug Delivery System Demand

4 Diffusion Controlled-Release Drug Delivery System Demand

5 Reservoir Controlled-Release Drug Delivery System Demand

6 Chewable Tablet Demand by Therapeutic Class

7 Orally Disintegrating Tablet Demand by Therapeutic Class

8 Nanoparticulate Oral Drug Delivery System Demand by Therapeutic Class

9 Oral Transmucosal Drug Delivery System Demand by Therapeutic Class

SECTION VI -- PARENTERAL DRUG DELIVERY SYSTEMS

1 Parenteral Drug Delivery System Demand by Type

2 Therapeutic Monoclonal Antibody Demand by Therapeutic Class

3 Therapeutic Monoclonal Antibodies Approved for US Sale

4 Prefilled Syringe Demand by Therapeutic Class

5 Encapsulated Parenteral Drug Delivery System Demand by Type & Therapeutic Class

6 Premixed IV Solution Demand by Therapeutic Class

SECTION VII -- INHALATION, TRANSDERMAL & IMPLANTABLE DRUG DELIVERY SYSTEMS

1 Other Drug Delivery System Demand by Type

2 Inhalation Drug Delivery System Demand by Type & Therapeutic Class

3 Transdermal Drug Delivery System Demand by Therapeutic Class

4 Implantable Drug Delivery System Demand by Type & Therapeutic Class

SECTION VIII -- APPLICATIONS

1 Drug Delivery System Demand by Therapeutic Class

2 Central Nervous System Drug Delivery Demand by Type

3 Respiratory Drug Delivery Demand by Type

4 Hormone & Related Drug Delivery Demand by Type

5 Gastrointestinal Drug Delivery System Demand by Type

6 Cardiovascular Drug Delivery System Demand by Type

7 Anti-Infective Drug Delivery System Demand by Type

8 Nutritional Delivery System Demand by Type

9 Biological Delivery System Demand by Type

10 Genito-Urinary Drug Delivery System Demand

11 Drug Delivery System Demand in Other Therapies

SECTION IX -- INDUSTRY STRUCTURE

1 Drug Delivery Revenues by Company, 2007

2 Selected Acquisitions & Divestitures

3 Selected Cooperative Agreements

LIST OF CHARTS

SECTION III -- DRUG DELIVERY MATERIALS

1 Drug Delivery Material Demand by Type, 2007

SECTION IV -- DRUG DELIVERY SYSTEMS OVERVIEW

1 Drug Delivery System Demand by Dosage Formulation, 2007

SECTION V -- ORAL DRUG DELIVERY SYSTEMS

1 Oral Drug Delivery System Demand by Type, 2007

SECTION VI -- PARENTERAL DRUG DELIVERY SYSTEMS

1 Parenteral Drug Delivery System Demand by Type, 2007

SECTION VII -- INHALATION, TRANSDERMAL & IMPLANTABLE DRUG DELIVERY SYSTEMS

1 Inhalation, Transdermal & Implantable Drug Delivery

System Demand by Type, 2007

SECTION VIII -- APPLICATIONS

1 Drug Delivery System Demand by Therapeutic Class, 2007

SECTION IX -- INDUSTRY STRUCTURE

1 US Drug Delivery Product Sales by Company, 2007

Abstract

Demand to grow more than 10% annually through 2012
US demand for drug delivery systems is projected to expand more than ten percent annually to $132 billion in 2012. Growth opportunities for drug delivery systems extend into all therapeutic classes of pharmaceuticals and encompass a wide range of compounds and formulations. Central nervous system, respiratory and hormone and related agents will remain the top three applications based on the special formulating needs of medicines for conditions such as arthritis, multiple sclerosis, asthma, allergies and cancer. However, favorable growth opportunities will emerge for drug delivery systems in most other therapeutic classes due to safety and efficacy shortcomings in many conventional medicines.

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