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Launching Combination Products: Brand extension and franchise development strategies

Published by: Business Insights

Published: Jan. 1, 2008 - 101 Pages


Table of Contents


Launching combination products

Executive Summary

An introduction to combination products

Combination product strategies in the cardiovascular market

Combination product strategies in the respiratory market

Combination product strategies in the diabetes market

Combination product strategies in the HIV market

Combination product strategies in the women’s health market

Combination product strategies in other therapeutic markets

Brand extension and franchise development strategies

Chapter 1 An introduction to combination products

Summary

Introduction

Therapeutic value

Combining therapies

Improved convenience

Commercial value

Brand extension

Franchise development

Leading combination products

Key products

Key therapeutic categories

Key combination product strategies

Chapter 2 Strategies for cardiovascular products

Summary

Introduction

Leading combination products

Recent combination product launches

Exforge

Future combination product developments

Simcor

Avandia/simvastatin

Key combination product launch strategies

Chapter 3 Strategies for respiratory products

Summary

Introduction

Leading combination products

Recent combination product launches

Symbicort

Future combination product developments

Singulair/Claritin

Flutiform

Key combination product launch strategies

Chapter 4 Strategies for diabetes products

Summary

Introduction

Leading combination products

Recent combination product launches

Janumet

Duetact

Future combination product developments

Avandia/simvastatin

Synordia

Key combination product launch strategies

Chapter 5 Strategies for HIV products

Summary

Introduction

Leading combination products

Recent combination product launches

Atripla

Future combination product developments

Key combination product launch strategies

Chapter 6 Strategies for women’s health products

Summary

Introduction

Leading combination products

Recent combination product launches

Lybrel

Angeliq

Future combination product developments

Aprela

DUB-OC

Key combination product launch strategies

Chapter 7 Strategies for other therapeutic areas

Summary

Introduction

Leading combination products

Anti-infectives

Recent combination product launches

Combigan

Ziana

Pylera

Future combination product developments

Oncology

CNS and pain

Key combination product launch strategies

Chapter 8 Brand extension and franchise development strategies

Summary

Introduction

Case studies

Diovan, Diovan HCT/Co-Diovan and Exforge

Avandia, Avandamet and Avandaryl

Advair/Seretide

Case study: Kaletra

Case study: Vytorin

Key success factors

Branding

Pricing

Positioning

Chapter 9 Appendix

Sources

Product sales data

Regulatory data

Specific sources

List of Figures

Figure 1.1: Number of combination products by therapy area, 2006

Figure 1.2: Key combination product strategies

Figure 2.3: Key cardiovascular combination product strategies

Figure 3.4: Key respiratory combination product strategies

Figure 4.5: Key diabetes combination product strategies

Figure 6.6: Key women’s health combination product strategies

Figure 8.7: Diovan, Diovan HCT/Co-Diovan sales, 2002-2006

Figure 8.8: Avandia, Avandamet and Avandaryl sales, 2002-2006

Figure 8.9: Advair/Seretide, Flovent/Flixotide and Serevent sales, 2002-2006

Figure 8.10: Kaletra sales, 2002-2006

Figure 8.11: Vytorin, Zetia and Zocor sales, 2002-2006

List of Tables

Table 1.1: Leading brand extension combination products, 2006

Table 1.2: Leading brand extension combination products, 2006

Table 1.3: Leading franchise development combination products, 2006

Table 2.4: Leading brand extension combination products in the cardiovascular market, 2004- 2006

Table 2.5: Leading franchise development combination products in the cardiovascular market, 2004-2006

Table 2.6: Recently approved combination products in the cardiovascular market, 2005-2007

Table 2.7: Future combination products in development for the cardiovascular market, 2007

Table 3.8: Leading brand extension combination products in the respiratory market, 2004-2006

Table 3.9: Leading franchise development combination products in the respiratory market, 2004- 2006

Table 3.10: Recently approved combination products in the respiratory market, 2005-2007

Table 3.11: Future combination products in development for the respiratory market, 2007

Table 4.12: Leading brand extension combination products in the diabetes market, 2004-2006

Table 4.13: Recently approved combination products in the diabetes market, 2005-2007

Table 4.14: Future combination products in development for the diabetes market, 2007

Table 5.15: Leading franchise development combination products in the HIV market, 2004-

Table 5.16: Recently approved combination products in the HIV market, 2005-2007

Table 6.17: Leading brand extension combination products in the women’s health market, 2004- 2006

Table 6.18: Leading franchise development combination products in the women’s health market, 2004-2006

Table 6.19: Recently approved combination products in the women’s health market, 2005-2007

Table 6.20: Future combination products in development for the women’s health market, 2007

Table 7.21: Leading brand extension combination products in other therapeutic markets, 2004- 2006

Table 7.22: Leading franchise development combination products in other therapeutic markets, 2004-2006

Table 7.23: Recently approved combination products in other therapeutic markets, 2005-2007

Table 7.24: Future combination products in development for other therapeutic markets, 2007

Abstract

Combination pharmaceutical products, or fixed-dose combinations (FDC’s), offer benefits to many drug classes due to the additive nature of therapeutic effect and the reduced level of side-effects associated with their use. Their core advantage however is an improvement in convenience that stems from reducing prescription numbers and their associated administrative costs. Although fixed-dose combination drugs have historically attracted disapproval from physicians, who typically prefer to determine the components and ratios of drug applications at their own discretion, a widespread acknowledgement and acceptance of these therapies has now been established. This is largely due to their effectiveness in areas such as HIV and asthma, but the successful positioning of combination products remains difficult in therapeutic areas where combination therapies only provide marginally incremental benefits. Launching Combination Products is a new report published by Business Insights that provides detailed strategic guidance for the preparation and successful execution of combination product launches. This report performs a comprehensive examination of current competitive pressures, best practices and future developments in key therapeutic areas including cardiovascular, respiratory, HIV and women’s health. Detailed case studies also provide unique insights into the brand extension and franchise development strategies of leading companies and help to identify the key success factors behind recent combination product launches. Discover potential growth opportunities for your brands, identify future combination launches and use case studies to understand the most effective launch strategies across key therapeutic areas with this new report.

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