The Global Market for Sleep-Wake Disorders, 2005-2012 Trends, Opportunities, and Insights in a High-Value CNS Therapy Area : Market Research Report

The Global Market for Sleep-Wake Disorders, 2005-2012 Trends, Opportunities, and Insights in a High-Value CNS Therapy Area

Published by: Spectra Intelligence

Published: Dec. 9, 2005 - 78 Pages

List of Tables
List of Figures
Executive Summary: Objectives of the Report; Research Methodology
Chapter 1 Introduction to Sleep-Wake Disorders: Sleep Disorders
Chapter 2 The Market for Sleep-Wake Disorders: Sleep-Wake Disorders; Wake-Promotion; Insomnia; Wake-Promotion; Restless Legs Syndrome; Sleep Apnoea - An Emerging High-Growth Sector
Chapter 3 Drugs in Research and Development: Sleep-Wake Disorders; Research and Development Overview
Chapter 4 Market Analysis, Therapy Forecasting, and Prospect Mining: Sleep-Wake Disorders; Comparative Analysis: Sleep-Wake Disorder Product Sales; Prospect Mining; Sleep-Wake Disorder Prospects

Therapy Area Forecasts 2012 and 2020

Chapter 5 Report Synopsis

Sleep-Wake Disorders - Key Data Points

Bibliography and Reference Sources

List of Tables

Table 1.1 Insomnia Categorized by Duration of Symptoms

Table 1.2 Causes of Insomnia

Table 1.3 Symptoms of Narcolepsy

Table 1.4 Medical and Surgical Treatment Options for Sleep Apnoea

Table 2.1 Estimated Global Sales (US$) & Forecasts of Leading Drugs for Sleep-Wake Disorders, 2004-2012

Table 2.2 Marketed Drugs to Treat Insomnia, 2005

Table 2.3 Drugs in Development for Restless Legs Syndrome, 2005

Table 3.1 Drugs in Development for Sleep-Wake Disorders, 2005

Table 4.1 Global Market for Sleep-Wake Pharmacotherapies (US$m), 2004-2012

Table 4.2 Therapy Area Forecasts for Sleep-Wake Disorders, 2012 & 2020

List of Figures

Figure 2.1 Estimated Sales (US$) and Forecasts of Sleep-Wake Disorder Drugs Segmented by Therapeutic Area, 2004-2012

Figure 2.2 Estimated Global Market Share of Sleep-Wake Disorder Drugs by Therapy Area, 2005 & 2012

Figure 4.1 Sleep-Wake Disorder Therapy Area Forecasts, 2005 & 2012 (US$m)

Figure 4.2 Comparative Analysis of Leading Sleep-Wake Disorder Products, 2004-2012 (US$m)

Figure 4.3 Key Sleep-Wake Disorder Drug Prospects, 2005

Abstract

The market for sleep-wake disorders is expanding based on new indications and novel drugs which offer efficacious sleep solutions and wake-promoting effects while limiting adverse side effects that are associated with conventional drugs. In a global market estimated at US$4.3 billion and forecast to increase 158% to US$11 billion by 2012, drugs for sleep-wake disorders such as insomnia, excessive daytime sleepiness, shift-work sleep disorder, sleep apnoea, and restless legs syndrome are predicted to transform the market to a high-value CNS therapy area within a decade. Furthermore, new therapies in the pipeline that provide complete sleep solutions to patients with impaired sleep-wake rhythms or drugs that improve wakefulness in occupational settings will offer new market opportunities and treatment options.

Trailblazer Cephalon has been integral in expanding the wake-promotion sector with Provigil and has stimulated the market to develop more drugs for conditions such as sleep apnoea, occupational shift-work disorders, and delayed-phase circadian rhythm disorders. Despite an optimistic outlook, immediate challenges in the market include short-term saturation in the insomnia therapy area as three new products were recently approved, namely Ambien CR, Lunesta, and Rozerem, with up to four further drugs expected to be approved and launched over the next 18 months including Indiplon, Gaboxadol, Doxepin, and Posidorm. In view of expanded product choice companies will need to adopt aggressive marketing approaches and utilize key therapeutic differentiators to claim market share for their products. However, the majority of sleep-wake disorders are underdiagnosed or misdiagnosed which indicates a significant market opportunity for manufacturers to redefine marketing strategies to optimize revenues for their products. This report comments on strategic and commercial issues that may affect current product positioning and discusses key compounds that have the potential to become high-value products over the next decade. The report also provides insights into forthcoming market dynamics and product sales to 2012 to enable the reader to make assumptions about future markets and prospects, and utilize the data for proprietary predictive market modelling.

REPORT HIGHLIGHTS AND KEY FINDINGS

The current market for sleep-wake disorders is valued at US$4.3 billion, which is forecast to increase 158% CAGR to US$11 billion by 2012

Critical analysis of insomnia, excessive daytime sleepiness, narcolepsy, sleep apnoea, shift-work sleep disorder, and restless legs syndrome
Review of epidemiological, aetiological, and demographic data for sleep-wake disorders
Analysis of over 10 key marketed products and inclusion of 30 R&D candidates identified in preclinical to clinical stages of development for sleep-wake disorders
Sales estimates (US$) to 2012 for major therapy areas
Strategic insights for life-cycle optimization and product development
Critical evaluation of leading sleep-wake disorder pharmacotherapies
Trend analysis of industry events and activities over past 2 years
Detailed R&D themes and clusters by therapy area
Data generation on sector and market values between 2004 and 2012 and therapy forecasts by 2020 (US$)
High revenue-yielding prospects identified with projected sales estimations
R&D pipeline positioning for novel candidates
Market insights for product development and drug promotion

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The Global Market for Sleep-Wake Disorders, 2005-2012 Trends, Opportunities, and Insights in a High-Value CNS Therapy Area

Table of Contents

Abstract