Drug Delivery Technologies: Players, Products & Prospects to 2015

Published by: Espicom Healthcare Intelligence

Published: Nov. 16, 2007 - 454 Pages

Table of Contents

Executive Summary

Competitor Ratio Analysis Summary

Introduction

Overview Of Delivery Technologies For Genetic Material: Past, Present & Future

Nucleic Acid Delivery: Motivators & Resistors

Motivators

Resistors

Nucleic Acid Delivery Technologies

Types Of Nucleic Acid Based Products Under Development By The Pharma Industry

Viral Vector Delivery Of Nucleic Acids

Figure 1: Schematic Of Gene Therapy Utilising An Aav Vector

Figure 2: Schematic Of Gene Therapy Utilising Hvj Envelope - Virosome

Non-viral Vector Delivery Of Nucleic Acids

Figure 3: Stable Nucleic Acid-lipid Particles

Figure 4: Targeted Nanoparticles

Figure 5: Schematic Of Macroflux Technology

Figure 6: Schematic Of Pmed Technology And Delivery

Table 1: Advantages And Disadvantages Of Nucleic Acid Platforms

Current Therapeutic Applications For The Viral And Non-viral Delivery Of Nucleic Acids

Leading Nucleic Acid Based Products In Development

Table 2: Nucleic Acid-based Approved/Filed Drugs

Table 3: Selection Of Nucleic Acid-based Developmental Drugs

Future Commercial Applications & Opportunities

Strategies Of Drug Delivery Companies

Leading Nucleic Acid Drug Delivery Companies

Table 4: Leading Nucleic Acid Drug Delivery Specialists

Partnerships & Acquisitions

Strategic Developmental & Commercialisation Partnerships

Mergers & Acquisitions

Table 5: Recent Partnerships & Acquisitions In The Nucleic Acid Field

Intellectual Property

Table 6: Nucleic Acid Patents

The Viral And Non-viral Vector Delivery Market

Now 2007

Table 7: Approved Nucleic Acid Product Sales

Future 2015

Table 8: Global Controlled-release Product Sales

Table 9: Novel Nucleic Acid Product Sales

Competitor Analysis

Movers & Shakers: Cutting Edge Or Losing Their Grip

Table 10: Movers & Shakers In Nucleic Acid Drug Delivery Systems

Company Profiles

Alphavax, Inc. (Www.Alphavax.Com)

Figure 7: The Alphavaccine Platform System

Table 11: Alphavax Product Pipeline

Table 12: Alphavax’ Sales Forecasts (Us$ Million)

Altea Therapeutics, Inc. (Www.Alteatherapeutics.Com)

Table 13: Altea Therapeutics’ Product Pipeline

Ap Pharma, Inc (Www.Appharma.Com)

Table 14: Ap Pharma’s Product Pipeline

Aradigm, Inc (Www.Aradigm.Com)

Table 15: Aradigm’s Product Pipeline

Biodelivery Sciences International (Www.Biodeliverysciences.Com)

Figure 8: Bioral Technology

Figure 9: Direct Membrane Fusion

Table 16: Bdsi’s Product Pipeline

Calando Pharmaceuticals (Www. Calandopharma.Com)

Figure 10: Schematic Of Cyclodextrin Polymeric Nanoparticles

Table 17: Calando’s Product Pipeline

Table 18: Calando’s Sales Forecasts

Copernicus Therapeutics (Www.Cgsys.Com)

Figure 11: Uptake And Trafficking Of Condensed Nanoparticle Dna

Table 19: Copernicus’ Product Pipeline

Table 20: Copernicus’ Sales Forecasts

Diatos Sa (Www.Diatos.Com)

Table 21: Diatos’ Product Pipeline

Dor Biopharma, Inc (Www.Dorbiopharma.Com)

Table 22: Dor’s Product Pipeline

Expression Genetics, Inc (Www.Egencorp.Com)

Figure 12: Theraplas Technology Platform

Table 23: Egen’s Product Pipeline

Table 24: Egen’s Sales Forecasts

Inovio Biomedical Corporation (Www.Inovio.Com)

Figure 13: Inovio’s Gene Delivery Platform

Table 25: Inovio’s Product Pipeline

Table 26: Inovio’s Sales Forecasts

Macroflux Corporation (Www.Macroflux.Com)

Table 27: Macroflux’ Product Pipeline

Maxcyte, Inc (Www.Maxcyte.Com)

Figure 14: Maxcyte’s Gt Ex-vivo Cell Loading System

Table 28: Maxcyte’s Product Pipeline

Mirus Bio Corporation (Www.Mirusbio.Com)

Figure 15: Polyconjugates - Sirna Delivery System

Table 29: Mirus’ Product Pipeline

Table 30: Mirus’ Sales Forecasts

Nanotherapeutics Inc. (Www.Nanotherapeutics.Com)

Table 31: Nanotherapeutics’ Product Pipeline

Neopharm (Www.Neopharm.Com)

Table 32: Neopharm’s Product Pipeline

Novagali Pharma Sa (Www.Novagali.Com)

Table 33: Novagali’s Product Pipeline

Pci Biotech (Www.Pcibiotech.Com)

Table 34: Pci’s Product Pipeline

Powdermed Inc (Www.Powdermed.Com)

Table 35: Powdermed’s Product Pipeline

Table 5.2.25: Powdermed’s Sales Forecasts

Protiva Biotherapeutics, Inc (Www.Protivabio.Com)

Table 37: Protiva’s Product Pipeline

Table 38: Protiva’s Sales Forecasts

Silence Therapeutics Plc (Www.Silence-therapeutics.Com)

Table 39: Silence Therapeutics’ Product Pipeline

Table 40: Silence Therapeutics’ Sales Forecasts

Supratek Pharma Inc. (Www.Supratek.Com)

Table 40: Supratek’s Product Pipeline

Tekmira Pharmaceuticals Corporation (Www.Tekmirapharm.Com)

Table 42: Tekmira’s Product Pipeline

Table 43: Tekmira’s Sales Forecasts

Vical Inc. (Www.Vical.Com)

Table 44: Vical’s Product Pipeline

Table 45: Vical’s Sales Forecasts

Appendix 1

Table 46: Global Nucleic Acid Approved Drugs Sales 2006a-20015e

Appendix 2

Table 47: Global Nucleic Acid Developmental Drugs Sales 2006a-20015e

Appendix 3

Competitor Ratio Analysis Criteria

Table 48: Key Nucleic Acid Delivery Companies By 2015

Bibliography

Glossary

Acronyms

Footnote References

Executive Summary

Competitor Ratio Analysis Summary

Introduction

Overview Of Controlled-release Delivery: Past, Present & Future

Controlled-release Delivery: Motivators & Resistors

Motivators

Resistors

Controlled-release Delivery: Impact On Product Lifecycles

Controlled-release Delivery

Types Of Controlled-release Delivery Used By Pharma Industry

Activated Controlled-release Delivery

Figure 1: Activated Controlled-release Delivery - Alza’s Oros Systems

Degradation Controlled-release Delivery

Figure 2: Degradation Controlled-release Delivery - Skyepharma’s Geomatrix

Diffusion Controlled-release Delivery

Figure 3: Monolithic Diffusion Controlled-release Delivery - Labopharm’s Contramid

Figure 4: Reservoir Diffusion Controlled-release Delivery - Impax’ Cmds

Figure 5: Combined Controlled-release Delivery - Flamel’s Micropump

Table 1: Advantages And Disadvantages Of Controlled-release Platforms

Current Therapeutic Application Of Controlled-release In Drug Delivery

Leading Brands That Utilise Controlled-release Delivery

Table 2: Controlled-release Approved Drugs

Future Commercial Applications & Opportunities

Strategies Of Drug Delivery Companies

Leading Controlled-release Drug Delivery Companies

Table 3: Leading Controlled-release Drug Delivery Companies

Partnerships & Acquisitions

Strategic Developmental & Commercialisation Partnerships

Merger & Acquisitions

Table 4: Recent Partnerships & Acquisitions In The Controlled-release Field

Intellectual Property

Table 5: Controlled-release Patents

The Controlled-release Market

Now 2007

Table 6: Approved Controlled-release Product Sales

Future 2015

Table 7: Global Controlled-release Product Sales

Table 8: Novel Controlled-release Product Sales

Competitor Analysis

Movers & Shakers: Cutting Edge Or Losing Their Grip

Table 9: Movers & Shakers In Controlled-release Drug Delivery Systems

Company Profiles

Alpharx Corporation (Www.Alpharx.Com)

Table 10: Alpharx’ Product Pipeline

Table 11: Alpharx’ Drug Delivery Sales

Alza Corporation (Www.Alza.Com)

Table 12: Alza’s Product Pipeline

Table 13: Alza’s Drug Delivery Sales

Andrx Corporation (Www.Watsonandandrx.Com)

Table 14: Andrx’ Product Pipeline

Table 15: Andrx’ Drug Delivery Sales

Antares Pharma, Inc. (Www.Antarespharma.Com)

Table 16: Antares’ Product Pipeline

Table 17: Antares’ Drug Delivery Sales

Biovail International (Www.Biovail.Com)

Table 18: Biovail’s Product Pipeline

Table 19: Biovail’s Drug Delivery Sales

Camurus Ab (Www.Camurus.Se)

Table 20: Camurus Ab’s Product Pipeline

Table 21: Camurus Ab’s Drug Delivery Sales

Cipher Pharmaceuticals, Inc. (Www.Cipherpharma.Com)

Table 22: Cipher’s Product Pipeline

Table 23: Cipher’s Drug Delivery Sales

Debiopharm (Www.Debio.Com)

Table 24: Debiopharm’s Product Pipeline

Table 25: Debiopharm’s Drug Delivery Sales

Delsite Biotechnologies, Inc. (Www.Delsite.Com)

Table 26: Delsite’s Product Pipeline

Depomed, Inc. (Www.Depomedinc.Com)

Table 27: Depomed’s Product Pipeline

Table 28: Depomed’s Product Sales

Durect Corporation (Www.Durect.Com)

Table 29: Durect’s Product Pipeline

Table 30: Durect’s Product Sales

Eiffel Technologies (Www.Eiffeltechnologies.Com.Au)

Table 31: Eiffel’s Product Pipeline

Elan Corporation (Www.Elan.Com)

Table 32: Elan’s Product Pipeline

Table 33: Elan’s Drug Delivery Sales

Elite Pharmaceuticals, Inc. (Www.Elitepharma.Com)

Table 34: Elite’s Product Pipeline

Table 35: Elite’s Product Sales

Endo Pharmaceuticals, Inc. (Www.Endo.Com)

Table 36: Endo’s Product Pipeline

Table 37: Endo’s Product Sales

Ethypharm Sa (Www.Ethypharm.Com)

Table 38: Ethypharm’s Product Pipeline

Table 39: Ethypharm’s Product Sales

Eurand (Www.Eurand.Com)

Table 40: Eurand’s Product Pipeline

Table 41: Eurand’s Product Sales

Flamel Technologies, Inc. (Www.Flamel.Com)

Table 42: Flamel’s Product Pipeline

Table 43: Flamel’s Product Sales

Glycologic, Ltd (Www.Glycologic.Co.Uk)

Table 44: Glycologic’s Product Pipeline

Impax Laboratories, Inc. (Www.Impaxlabs.Com)

Table 45: Impax’ Product Pipeline

Table 46: Impax’s Product Sales

Kv Pharmaceuticals, Inc (Www.Kvpharmaceutical.Com)

Table 47: Kv’s Product Pipeline

Labopharm, Inc. (Www.Labopharm.Com)

Table 48: Labopharm’s Product Pipeline

Table 49: Labopharm’s Product Sales

Lavipharm Sa (Www.Lavipharm.Com)

Table 50: Lavipharm’s Product Pipeline

Table 51: Lavipharm’s Product Sales

Octoplus N.V. (Www.Octoplus.Nl)

Table 52: Octoplus’ Product Pipeline

Table 53: Octoplus’ Product Sales

Penwest Pharmaceuticals (Www.Penw.Com)

Table 54: Penwest’s Product Pipeline

Table 55: Penwest’s Product Sales

Protherics (Www.Protherics.Com)

Table 56: Protherics’ Product Pipeline

Table 57: Protherics’ Drug Delivery Sales

Scolr Pharma, Inc. (Www.Scolr.Com)

Table 58: Scolr’s Product Pipeline

Table 59: Scolr’s Drug Delivery Sales

Shire (Www.Shire.Com)

Table 60: Shire’s Product Pipeline

Table 61: Shire’s Drug Delivery Sales

Skinvisible, Inc. (Www.Skinvisible.Com)

Table 62: Skinvisible’s Product Pipeline

Skyepharma (Www.Skyepharma.Com)

Table 63: Skyepharma’s Cr Product Pipeline

Table 64: Skyepharma’s Controlled-release Product Sales

Spherics (Www.Spherics.Com)

Table 65: Spheric’s Product Pipeline

Appendix 1

Table 66: Global Controlled-release Approved Drugs Sales 2006a-20015e

Appendix 2

Table 67: Global Controlled-release Developmental Drugs Sales 2006a-20015e

Appendix 3

Competitor Ratio Analysis Criteria

Table 68: Key Controlled-release Delivery Companies By 2015

Bibliography

Glossary

Acronyms

Executive Summary

Competitor Ratio Analysis Summary

Introduction

Overview Of Nanotechnology: Past, Present & Future

Figure 1: Top Ten Applications Of Nanotechnology In Developing Countries

Nanotechnology: Motivators & Resistors

Motivators

Resistors

Nanotechnology: Impact On Product Lifecycles

Nanotechnology In Drug Delivery

Core Nanotechnology Used By The Pharma Industry

Nano-engineered Drugs

Nano-carriers

Figure 2: Dendrimer Structure

Figure 3: Liposome Structure

Figure 4: Micelle Structure

Current Therapeutic Application Of Nanotechnology In Drug Delivery

Leading Brands That Utilise Nanotechnology Delivery

Table 1: Nanotechnology-enabled Approved Drugs

Future Commercial Applications & Opportunities

Strategies Of Drug Delivery Companies

Leading Nanotechnology Drug Delivery Companies

Table 2: Leading Nanotechnology-enabled Drug Delivery Companies

Partnerships & Acquisitions

Strategic Development & Commercialisation Partnerships And Joint Ventures

Table 3: Recent Partnerships & Acquisitions In The Nanotechnology Field

Mergers & Acquisitions

Table 4: Nanotechnology Patents

The Nanotechnology Market

Now 2007

Table 5: Approved Nano-enabled Product Sales

Future 2015

Table 6: Novel Nano-enabled Product Sales

Table 7: Global Nano-enabled Product Sales

Competitor Analysis

Movers & Shakers: Cutting Edge Or Losing Their Grip

Table 8: Movers & Shakers In Nanotechnology Drug Delivery Systems

Company Profiles

Abraxis Bioscience (Www.Abraxisbio.Com)

Table 9: Abraxis’ Product Pipeline

Table 10: Abraxis Drug Delivery Sales

Access Pharmaceuticals (Www.Accesspharma.Com)

Table 11: Access Pharmaceuticals Product Pipeline

Alpharx Corporation (Www.Alpharx.Com)

Table 12: Alpharx’ Product Pipeline

Table 13: Alpharx’ Pharmaceuticals Drug Delivery Sales

Alza Corporation (Www.Alza.Com)

Table 14: Alza’s Drug Delivery Sales

Biosante Pharmaceuticals (Www.Biosantepharma.Com)

Table 15: Biosante’s Product Pipeline

Table 16: Biosante’s Drug Delivery Sales

Camurus Ab (Www.Camurus.Se)

Table 17: Camurus Ab’s Product Pipeline

Table 18: Camurus Ab’s Drug Delivery Sales

Eiffel Technologies (Www.Eiffeltechnologies.Com)

Table 19: Eiffel’s Product Pipeline

Elan Corporation (Www.Elan.Com)

Table 20: Elan’s Product Pipeline

Table 21: Elan’s Drug Delivery Sales

Eurand (Www.Eurand.Com)

Table 22: Eurand’s Product Pipeline

Gilead Sciences (Www.Gilead.Com)

Table 23: Gilead Sciences’ Product Pipeline

Table 24: Gilead Sciences’ Drug Delivery Sales

Nano Interface Technology (Www.Nanointerfacetech.Com)

Table 25: Niti’s Product Pipeline

Nano S Biotechnology Gmbh (Www.Nano-s.Com)

Table 26: Nano S’ Product Pipeline

Nanobio Corporation (Www.Nanobio.Com)

Table 27: Nanobio’s Product Pipeline

Table 28: Nanobio’s Drug Delivery Sales

Nanobiomagnetics (Www.Nanobmi.Com)

Table 29: Nanobiomagnetics’ Product Pipeline

Nanobiotix (Www.Nanobiotix.Com)

Table 30: Nanobiotix’ Product Pipeline

Nanocarrier (Www.Nanocarrier.Co.Jp)

Table 31: Nanocarrier’s Product Pipeline

Table 32: Nanocarrier’s Drug Delivery Sales

Nanotechnology Victoria, Ltd (Www.Nanovic.Com)

Table 33: Nanovic’s Product Pipeline

Nanomaterials Technology (Www.Nanomt.Com)

Table 34: Nanomaterial’s Product Pipeline

Nanotherapeutics (Www.Nanotherapeutics.Com)

Table 35: Nanotherapeutics’ Product Pipeline

Table 36: Nanotherapeutics’ Drug Delivery Sales

Novavax (Www.Novavax.Com)

Table 37: Novavax’s Product Pipeline

Table 38: Novavax’s Drug Delivery Sales

Skyepharma (Www.Skyepharma.Com)

Table 39: Skyepharma’s Product Pipeline

Table 40: Skyepharma’s Product Sales

Spherics (Www.Spherics.Com)

Table 41: Spheric’s Product Pipeline

Appendix 1

Table 42: Global Nanotechnology Approved Drugs Sales 2006a-20015e

Appendix 2

Table 43: Global Nanotechnology Developmental Drugs Sales 2006a-20015e

Appendix 3

Competitor Ratio Analysis Criteria

Table 44: Key Nanotechnology Delivery Companies By 2015

Bibliography

Glossary

Acronyms

Executive Summary

Competitor Ratio Analysis Summary

Introduction

Overview Of Delivery Technologies For Systemic Targeted Delivery: Past,

Present & Future

Systemic Targeted Delivery: Motivators & Resistors

Motivators

Resistors

Systemic Targeted Delivery Technologies

Types Of Systemic Targeted Delivery Platform In Development In The Pharma Industry

Targeting Ligands

Figure 1: Antibody-directed Enzyme Prodrug Targeted Delivery

Figure 2: Peptide-induced Release For Targeted Delivery

Figure 3: Nucleomic Mediated Targeted Intranuclear Delivery

Figure 4: Vitamin Mediated Targeted Intracellular Delivery - Cobalamin

Non-biological Targeting Platforms

Figure 5: Photosensitive Targeted Delivery

Current Therapeutic Applications For Systemic Targeted Delivery

Leading Systemic Targeted Products In Development

Table 1: Approved Systemic And Targeted Drugs

Future Commercial Applications & Opportunities

Strategies Of Drug Delivery Companies

Leading Targeted Drug Delivery Companies

Table 2: Leading Systemic Targeted Delivery Specialists

Partnerships & Acquisitions

Strategic Alliances

Strategic Acquisitions

Table 3: Recent Market Activity In Targeted Delivery Companies

Intellectual Property

Table 4: Targeted Drug Delivery Patents

The Targeted Delivery Market

Now 2007

Table 5: Approved Targeted Delivery Product Sales

Future 2015

Table 6: Global Controlled Release Product Sales

Table 7: Novel Targeted Delivery Product Sales

Competitor Analysis

Movers & Shakers: Cutting Edge Or Losing Their Grip

Table 8: Movers & Shakers In Targeted Drug Delivery Systems

Company Profiles

Access Pharmaceuticals (Www.Accesspharma.Com)

Figure 6: Schematic Of Targeted Nanoparticle

Table 9: Targeted Delivery Of Cancer Subtypes Via Folate Polymer, Vitamin B12 Polymer And Biotin Polymers

Table 10: Access Pharmaceuticals’ Product Pipeline

Table 11: Access Pharmaceuticals’ Targeted Delivery Sales Forecasts

Alza (Www.Alza.Com)

Table 12: Alza’s Product Pipeline

Table 13: Alza’s Targeted Drug Delivery Sales

Avidimer Therapeutics (Www.Avidimer.Com)

Table 14: Avidimer’s Product Pipeline

Table 15: Avidimer'S Targeted Drug Delivery Sales

Calando Pharmaceuticals (Www. Calandopharma.Com)

Figure 7: Schematic Of Cyclodextrin Polymeric Nanoparticles

Table 16: Calando’s Product Pipeline

Table 17: Calando’s Targeted Delivery Sales Forecasts

Cell Therapeutics (Www.Ctiseattle.Com)

Figure 8: Cti’s Polyglutamate Polymer Technology

Table 18: Cti’s Product Pipeline

Copernicus Therapeutics (Www.Cgsys.Com)

Table 20: Copernicus’ Product Pipeline

Table 21: Copernicus’ Targeted Delivery Sales Forecasts

Diatos Sa (Www.Diatos.Com)

Table 22: Diatos’ Product Pipeline

Table 23: Diatos’ Targeted Drug Delivery Sales

Enzon Pharmaceuticals, Inc. (Www.Enzon.Com)

Table 24: Enzon’s Product Pipeline

Table 25: Enzon’s Targeted Product Sales

Endocyte Inc. (Www.Endocyte.Com)

Table 26: Endocyte’s Product Pipeline

Table 27: Endocyte’s Targeted Drug Delivery Sales

Eurand (Www.Eurand.Com)

Table 28: Eurand’s Product Pipeline

Immunogen (Www.Immunogen.Com)

Table 29: Immunogen’s Product Pipeline

Table 30: Immunogen’s Targeted Delivery Sales

Imarx Therapeutics (Www.Imarx.Com)

Table 31: Imarx’ Product Pipeline

Table 32: Imarx’ Targeted Product Sales

Insert Therapeutics (Www.Insertt.Com)

Figure 9: Schematic Of Cyclosert’s Nanoparticle Mediated Drug Delivery To Solid Tumours

Table 33: Insert Therapeutics’ Product Pipeline

Table 34: Insert Therapeutics' Targeted Product Sales

Mirus Bio Corporation (Www.Mirusbio.Com)

Figure 10: Polyconjugates - Sirna Delivery System

Table 35: Mirus’ Product Pipeline

Nanobiomagnetics, Inc (Www.Nanobmi.Com)

Table 36: Nanobiomagnetics’ Product Pipeline

Nanobiotix (Www.Nanobiotix.Com)

Table 37: Nanobiotix’ Product Pipeline

Nanocarrier (Www.Nanocarrier.Co.Jp)

Figure 11: Nanocoat Technology

Table 38: Nanocarrier’s Product Pipeline

Table 39: Nanocarrier’s Targeted Drug Delivery Sales

Neopharm (Www.Neopharm.Com)

Table 40: Neopharm’s Product Pipeline

Table 41: Neopharm’s Drug Delivery Sales

Novosom Ag (Www.Novosom.Com)

Figure 12: Schematic Of Smarticles Mechanism Of Targeted Delivery

Table 42: Novosom’s Product Pipeline

Pci Biotech As (Www.Photocure.Com)

Figure 13: Schematic Of Principle Of Pci Technology

Table 43: Pci’s Product Pipeline

Point Biomedical Corporation (Www.Pointbio.Com)

Figure 14: Schematic Of Point’s Bisphere

Table 44: Point’s Product Pipeline

Quest Pharmatech (Www.Questpharmatech.Com)

Table 45: Quest Pharmatech’s Product Pipeline

Seattle Genetics (Www.Seattlegenetics.Com)

Figure 15: Schematic Of Adc’s

Table 46: Seattle Genetic’s Product Pipeline

Table 47: Seattle Genetic’s Delivery Sales

Starpharma (Www.Starpharma.Com)

Table 48: Starpharma’s Product Pipeline

Supratek Pharma Inc. (Www.Supratek.Com)

Table 49: Supratek’s Product Pipeline

Tekmira Pharmaceuticals Corporation (Www.Tekmirapharm.Com)

Table 50: Tekmira’s Product Pipeline

Table 51: Tekmira’s Targeted Delivery Sales Forecasts

Appendix 1

Table 52: Global Targeted Approved Drugs Sales 2006a-20015e

Appendix 2

Table 53: Global Targeted Developmental Drugs Sales 2006a-20015e

Appendix 3

Competitor Ratio Analysis Criteria

Table 54: Key Targeted Delivery Companies By 2015

Bibliography

Glossary

Acronyms

Abstract

Providing...
Critical analyses and competitive ratings for major specialist developers
Unique sales forecasts to 2015 for key current and new products utilising drug delivery technologies
A comprehensive examination of the 4 major and compelling drug delivery sectors

While pharmaceutical sales have continued to rise steadily during the last five years generating over US$600 billion in 2006, the global drug delivery market has undergone rapid growth from an estimated US$26 billion in 2000 to approximately US$67 billion in 2006. This market has been driven by a number of factors including:
Patent expiration of leading brands forcing the pharmaceutical industry to evaluate ways to maximize product life-cycles through new formulations, combinations and repositioning;
Advances in new delivery technology (microencapsulation and nanotechnology); and
The development and cost-effective manufacture of new delivery materials (dendrimers, lipid formulations and biodegradable polymers).

Within this market there are a number of areas of advanced drug delivery which have attracted the attention of pharmaceutical industry and the investment community. The dramatic growth of the sector is reflected in the evolution of an array of delivery vehicles and hybrid platforms that are increasingly being used to deliver approved and novel therapeutic agents.

Focusing on the sectors that are driving growth!

VOLUME I
CONTROLLED- RELEASE DELIVERY

VOLUME II
NANO-ENABLED DELIVERY

VOLUME III
NUCLEIC ACID DELIVERY

VOLUME IV
TARGETED DELIVERY

Few sectors of the pharmaceutical industry will enjoy such a high level of growth in the future.

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