Medical Adhesives and Sealants

Published by: Global Industry Analysts

Published: Jul. 1, 2007 - 309 Pages

Table of Contents

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations

Disclaimers

Data Interpretation & Reporting Level

Quantitative Techniques & Analytics

Market Definitions and Scope of Study

I. Adhesives and Sealants for Dentistry

Denture and Orthodontic Bonding Agents

Pit & Fissure Sealants and Luting Cements

Restorative Adhesives & Sealants

Tray Adhesives

Dental Surgical Tissue Bonding Agents for Dental Reconstruction

II. Medical Adhesives & Sealants

Adhesives & Sealants for Surgical/Internal Medical Applications

Adhesives & Sealants for External Medical Applications

II. A US MARKET REPORT

1. Market Overview

Driven by High Penetration Rates

Medical Adhesives & Sealants Sitting Pretty

Overpowering Challenges

Industry Landscape Goes Thinner

A Peek into Products with Strong Demand Potential

Synthetics Outperforming Market Kinetics

Current and Future Analysis

By Market Segment/Application

Analysis by Product Chemistry

Table 1: Medical Adhesives and Sealants Market in the US: Percentage Breakdown by Product Chemistry for Synthetic Polymer Based Adhesives & Sealants and Natural Polymer Based Adhesives & Sealants for Years 2000, 2005, and 2010

Table 2: US Market for Synthetic Polymer Based Adhesives & Sealants by Application: Annual Sales for Dental and Medical Markets in US$ Million for Years 2000, 2005, and 2010 (includes corresponding Graph/Chart)

Table 3: US Market for Natural Polymer Based Adhesives & Sealants by Application: Annual Sales for Dental and Medical Markets in US$ Million for Years 2000, 2005, and 2010 (includes corresponding Graph/Chart)

Medical Adhesives Adhere to High Growth - An Evolving Outlook

2. Market Trends & Issues

Appeasing the Eye - The New ‘Functional’ Mantra

Denture Adhesives Pining for Innovation

Sprucing up the Dental Sealants Market

Table 4: Dental Adhesives Market in the US (2004): Percentage Breakdown of Value and Volume Sales by Retail Channel - Drug Stores, Super Markets, and Others (includes corresponding Graph/Chart)

Table 5: Leading Brands of Denture Adhesives in the US (2004): Percentage Breakdown of Sales for Fixodent, Super Poligrip, Sea-Bond, Fixodent Complete, Fixodent Free, Poligrip Free, Poligrip Ultra Fresh, Super Wernets, Cushion Grip, Dentu Grip, and Others (includes corresponding Graph/Chart)

Sealants Chink into the Mechanical Fasteners’ Market

Fibrin-based Products - A Brick in the Wall

Emergence of Topical Hemostats as Threat to Tissue Sealants

Tissue Sealants Fall Prey to Consumer Ignorance

Cosmetic Surgeries - Going ‘Invasive’ on Conventional Sealants

Cyanoacrylate Tissue Sealants - Arrival of an Enigma

Cyanoacrylate Medical Adhesives to Command Increased Market Penetration

Silicone Face-lifting Adhesive Market

Pit and Fissure Sealants Scoring High Grades

Growing Dental-Care Consciousness Dents Market

Maximizing on the ‘Minimal’ Market

High Resistance to Sterilization Props Growth in Allied Markets

Demand for Polyethylene Glycol and Plasma/Protein Sealants to Surge

Adhesives and Sealants to Witness Rapid Gains in Cardiovascular Procedures

3. Industry Overview

Hemostatic Agents and Tissue Sealants: Applications in Urology

Upsurge in Medical Adhesives and Sealants Market

US First-Aid Category Sounds Strong with Ample Choices

Biggies Drive the Innovation Trend

Bandage Market Catches up the Licensing Fetish

Private-Labeled Bandages Make their Presence Felt

Hemostatic Bandages Breathe an Air of Dynamism

Present Market Scenario: Reality ‘Bites’

Disposable Medical Devices - Key End-Use Application for Adhesives

Merging for Better

A Case for Consolidation

Stupendous Growth Lures Adhesive Majors

Synopsized Review of Growth Drivers

Information & Knowledge Dispersion: Key to Increased Consumer Adoption

Healthcare Budget Rationing: An Unlikely Growth Driver

FDA Approvals Spur Market Interest

Proven Clinical Evidences Boost the Market

Utility of Surgical Adhesives Soaring High

Regulatory Standards for Surgical Glues

US Scorecard for Surgical Adhesives

Table 6: A Historical Review of Adhesives & Sealants’ Usage in Surgical Procedures in the US: Percentage Share of Adhesives and Sealants’ Usage in Cardiovascular, Digestive, Ear, Endocrine System, Eye, Female Genital Organs, Hemic and Lymphatic System, Integumentary System, Male Genital Organs, Musculoskeletal System, Nervous System, Nose, Mouth, Pharynx, Obstetrical Procedures, Respiratory System and Urinary System Surgeries (includes corresponding Graph/Chart)

Tissue Adhesives and Sealants Harness Growth in the US Market

Tissue Sealants Bank Upon Growing Number of Approved Indications

Table 7: Tissue Sealants Market in the US (2003): Percentage Breakdown of the Usage by Type of Surgery - Abdominal Aortic Aneurysm, Burn Debridement, Coronary Artery Bypass Graft, Colon Resection, Hip Replacement, Knee Replacement, Mastectomy, Lung Resection, Liver Surgery Biopsy, Skin Grafting, Spinal Surgery and Others (includes corresponding Graph/Chart)

Competitive Landscape

Tentative Approvals Leading to a Weary Growth

Regulatory Concerns for Medical Adhesives and Sealants

4. Adhesives & Sealants - A Curtain Raiser

Adhesives

Sealants

Medical Adhesives vis-à-vis Industrial Grade Adhesives

Evolution of Adhesives

Pressure Sensitive Adhesives Bag Higher Attention

Tissue Sealants Make Surgeries Trouble-free

Banking on Ongoing Innovations

5. Segmental Overview

Application Specific Categorization of Medical Adhesives & Sealants

Other Categorizations of Medical Adhesives & Sealants

By Chemical Type

By Curing Methodology

By Functional Type

By Origin

By Physical Form

Adhesives and Sealants for Dentistry

A Backdrop

Emerging Adhesive and Sealant Application Trends in Dentistry

Harmful Cavities - A Sealant Seizure

Esthetic Dental Care

Dental Sealants and Composites - A Key Note

Composite Resins

Segmental Overview of Dental Adhesives & Sealants

Denture and Orthodontic Bonding Agents

Pit & Fissure Sealants and Luting Cements

Pit and Fissure Sealants

Luting Cements

Restorative Adhesives & Sealants

Dental Fluorosis - A Key Application Area

Glass Ionomers - Raging Hot in Restorative Dentistry

Tray Adhesives

Dental Surgical Tissue Bonding Agents for Dental Reconstruction

Medical Adhesives & Sealants for Surgical and External Applications

Adhesives & Sealants for Surgical/Internal Medical Applications

Vital Factors to be Considered While Using Surgical Adhesives

Significance of Surgical Adhesives and Sealants

Surgical Adhesive and Sealants Utility in Surgeries

Why Use Medical Adhesives and Sealants Over Traditional Sutures and Staples?

Surgical Sealants as an Adjunct to Sutures & Staples

A ‘Functional’ Invasion

A Focus on Surgical Adhesives & Sealants’ Applications in Surgical

Procedures

Surgical Sealants for PTCA Punctures

Adhesives & Sealants for External Medical Applications

Adhesives for Wound Management: Impressed by Value

6. A Peek into Product Chemistry

Chemical Nature of Adhesives & Sealants

Synthetic-Polymer based Adhesives and Sealants

Natural-Polymer based Adhesives and Sealants

Light-Curable Adhesives

Radiation-Cured Adhesives

Acrylics

Anaerobic Adhesives

Cyanoacrylate

Cyanoacrylate Tissue Sealants

Epoxies

Benefits of Epoxies

Silicones

Types of Silicone Adhesives

Advantages Offered by Silicone Pressure Sensitive Adhesives

Characteristic Traits of Silicones

Other Chemistries

Polymeric Adhesives

Thermosets

Thermoplastics

Polyurethane Adhesives

Benefits of Polyurethane

Drawbacks of Polyurethane

Hydrocolloids

Plasma & Protein based Sealants

Collagen-based Sealants

Fibrin Sealants

Human Recombinant Fibrin Sealant

Fibrin Sealant Application in Various Surgeries

Cardiac Surgery

Plastic Surgery

Thoracic Surgery

Vascular Surgery

Albumin-based Sealants

Bovine Serum Albumin

7. Technological Innovations

Researchers Discover Novel Bacterial Glue with Potential Medical Applications

Faster Time to Market Needs Shirk the Innovation Lull

Visible and Ultraviolet Light Cured Products

Under Trials

Surgical Sealants to Prevent Fluid & Air Leaches

Transparent Hydrogel for Eye Surgeries

8. Product Innovations/Introductions

Kimberly-Clark Releases InteguSeal Microbial Sealant

3M ESPE Upgrades Clicker™ Dispenser

Kerr Introduces NX3 Nexus® Third Generation

HemCon Launches Novel Dental Dressing

Rollprint Introduces Allegro® M Sealant

Scapa Medical Launches BioflexO Rx1207P

3M Launches Tegaderm Ag

Scapa Medical Develops Polyethylene and Polyurethane Adhesive Foams

Covalon’s Collagen-Based Wound Dressings Hit the Aisle

Johnson & Johnson Rolls out PROMOGRAN PRISMA™

Scapa Introduces Advanced Pressure Sensitive Adhesive

Bone Solutions Rolls Out Injectable Adhesive

DuraSeal Receives Marketing Approval from FDA

Scapa Medical Debuts Rubber-Based Medical Adhesives

Surgical Sealants Debuts Surgical Adhesive and Sealant Products

New Skin Crack Gel from CLOSURE Medical

Surgical Sealants Debuts Thorex

CLOSURE Medical Expands Dermabond® Family

9. Recent Industry Activity

CryoLife Signs Distribution Agreement with MAST Biosurgery

HemCon’s ChitoFlex Obtains CE Marking

3M Acquires OMNII Oral

ADEPT® Obtains FDA Approval

Approval of New Rigid Applicator Tip for Cryolife’s Bioglue®

HemCon to Distribute Bandages in South Africa

HemCon Changes Name to Hemcon Medical Technologies

CryoLife Associates with BioForm Medical

Nerites Seals a Pact with MORF

Tyco to Acquire Confluent Surgical

ThermoGenesis Signs Distribution Agreements for CryoSeal FS System

Apollo Acquires Two Divisions of Tyco

Johnson & Johnson Acquires CLOSURE Medical

DENTSPLY Embarks on Acquisitions to Boost Presence in Orthodontic Market

Baxter Collaborates with Kuros

Kensey and St. Jude Medical Revise Distribution Terms for Angio-Seal™

Innocoll to Tie Up with Surgical-IOC

Hemcon Ties up with TVF&R for Hemcon® Bandage

AMS’ Liquiband™ to Set Foot in the US Market

CryoLife Signs Endologix for BioFoam

Haemacure Ramps Up Production Capacity of Florida based Plant

Angiotech Signs up Orthovita for a Hemostat Product

Hemcon Expands its Bandage Production Center

Angiotech Purchases Assets of NeuColl

Angiotech Partners with Baxter

10. Focus on Select Key Players

3M

Adhesives Research, Inc

Aveva Drug Delivery Systems

Baxter International, Inc

Confluent Surgical, Inc

Covalence Specialty Materials Corp

CryoLife, Inc

Den-Mat Corporation

DENTSPLY International, Inc

Ethicon, Inc

CLOSURE Medical Corporation

HARTMANN-CONCO, Inc

HemCon Medical Technologies, Inc

Procter & Gamble Company

Protein Polymer Technologies, Inc

Schering-Plough Corp

Sybron Dental Specialties, Inc

Kerr Corporation

11. Market Analytics

Table 8: US Recent Past, Current & Future Analysis for Medical Adhesives and Sealants by Market Segment/ Application - Dental Adhesives & Sealants (Denture & Orthodontic Bonding Agents, Pit & Fissure Sealants and Luting Cements, Restorative Adhesives, Tray Adhesives, and Dental Surgical Tissue Bonding Agents) and Medical Adhesives & Sealants (Surgical/Internal, and External) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 9: US Long-term Projections for Medical Adhesives and Sealants by Market Segment/Application - Dental Adhesives & Sealants (Denture & Orthodontic Bonding Agents, Pit & Fissure Sealants and Luting Cements, Restorative Adhesives, Tray Adhesives, and Dental Surgical Tissue Bonding Agents) and Medical Adhesives & Sealants (Surgical/Internal, and External) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 10: US 10-Year Perspective for Medical Adhesives and Sealants by Market Segment/ Application - Percentage Breakdown of Dollar Sales for Dental Adhesives & Sealants (Denture & Orthodontic Bonding Agents, Pit & Fissure Sealants and Luting Cements, Restorative Adhesives, Tray Adhesives, and Dental Surgical Tissue Bonding Agents) and Medical Adhesives & Sealants (Surgical/Internal, and External) Markets for Years 2000, 2006, and 2010 (includes corresponding Graph/Chart)

III. COMPETITION

1. 3M Company (USA)

Table 11: Market Share Analysis by Segment: 2004-2006 (% Breakdown of Value Sales)

Table 12: Market Share Analysis by Geographic Region: 2004-2006 (% Breakdown of Value Sales)

Table 13: Annual Sales Analysis: 2004-2006 (In US$ billion)

Table 14: Annual Sales Analysis by Quarter: 2006 Vs. 2005 (In US$ billion)

Table 15: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In US$ billion)

Table 16: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In US$ billion)

Table 17: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ billion)

Table 18: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In US$ billion)

Table 19: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ billion)

3M ESPE (USA)

3M Medical Specialties & OEM Products (USA)

3M Unitek Corporation (USA)

2. Adchem Corporation (USA)

3. Adhesives Research, Inc. (USA)

4. Advanced Medical Solutions PLC (United Kingdom)

Table 20: Annual Sales Analysis: 2006 Vs.2005 (In £ million)

5. AliMed, Inc. (USA)

6. Angiotech Pharmaceuticals, Inc. (Canada)

Table 21: First Quarter Sales Analysis: 2007 Vs. 2006 (In US$ million)

Table 22: Annual Sales Analysis: 2006 Vs. 2005 (In US$ million)

Table 23: Annual Sales Analysis by Quarter: 2006 Vs. 2005 (In US$ million)

Table 24: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In US$ million)

Table 25: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In US$ million)

7. Avery Dennison - Specialty Tape Division (USA)

Table 26: Nine Months Sales Analysis by Quarter: 2004-2005 (Nine Months Ended, September) (In US$ billion)

Table 27: Nine Months Sales Analysis by Segment: 2004-2005 (Nine Months Ended, September) (In US$ billion)

8. Aveva Drug Delivery Systems (USA)

9. Basic Adhesives, Inc. (USA)

10. Baxter International, Inc. (USA)

Table 28: Annual Sales Analysis: 2004-2006 (In US$ million)

Table 29: Annual Sales Analysis by Quarter: 2006 Vs. 2005 (In US$ million)

Table 30: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 31: Annual Sales Analysis by Business Segment: 2005 Vs. 2004 (In US$ million)

Table 32: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

Baxter Healthcare Corporation (USA)

Table 33: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ billion)

11. BioForm Medical, Inc. (USA)

12. Bisco, Inc. (USA)

13. Bone Solutions, Inc. (USA)

14. BVM Medical Ltd (UK)

15. Collano, Inc. (USA)

16. Confluent Surgical, Inc. (USA)

17. Covalence Specialty Materials Corp. (USA)

Table 34: First Quarter Sales Analysis: 2007 Vs. 2006 (In US$ billion)

Table 35: Annual Sales Analysis: 2006 Vs. 2005 (In US$ billion)

18. CryoLife, Inc. (USA)

Table 36: Nine Months Sales Analysis: 2005-2006 (Nine Months Ended, September) (In US$ million)

Table 37: Nine Months Sales Analysis by Quarter: 2005-2006 (Nine Months Ended, September) (In US$ million)

Table 38: Nine Months Sales Analysis by Business Segment: 2005-2006 (Nine Months Ended, September) (In US$ million)

Table 39: Annual Sales Analysis: 2004-2005 (In US$ million)

Table 40: Annual Sales Analysis by Business Segment: 2004-2005 (In US$ million)

Table 41: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million)

Table 42: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million)

19. Danville Materials (USA)

20. Den Mat Corporation (USA)

21. DENTSPLY International, Inc. (USA)

Table 43: Nine Months Sales Analysis: 2005-2006 (Nine Months Ended, September) (In US$ million)

Table 44: Nine Months Sales Analysis by Quarter: 2005-2006 (Nine Months Ended, September) (In US$ million)

Table 45: Annual Sales Analysis: 2004-2005 (In US$ million)

Table 46: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million)

Table 47: Annual Sales Analysis by Segment: 2004-2005 (In US$ million)

Table 48: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million)

22. Corning Corporation (USA)

Table 49: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

23. DYMAX Corporation (USA)

24. Epoxy Technology (USA)

25. Ferndale Laboratories, Inc. (USA)

26. GC America, Inc. (USA)

27. GlaxoSmithKline PLC (United Kingdom)

Table 50: Market Share by Geographic Region: 2006 (% Breakdown of Value Sales)

Table 51: Annual Sales Analysis: 2006 Vs. 2005 (In £ million)

Table 52: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In £ million)

Table 53: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In £ million)

GlaxoSmithkline - Consumer Healthcare Ltd. (USA)

28. Haemacure Corporation (USA)

29. HARTMANN-CONCO, Inc. (USA)

30. HemCon Medical Technologies, Inc. (USA)

31. Henkel Loctite Corporation (USA)

32. Hollister, Inc. (USA)

33. Innovata PLC (United Kingdom)

34. Ivoclar Vivadent, Inc. (USA)

35. Johnson & Johnson (USA)

Table 54: Nine Months Sales Analysis: 2005-2006 (Nine Months Ended, September) (In US$ million)

Table 55: Nine Months Sales Analysis by Quarter: 2005-2006 (Nine Months Ended, September) (In US$ million)

Table 56: Nine Months Sales Analysis by Business Segment: 2005-2006 (Nine Months Ended, September) (In US$ million

Table 57: Nine Months Sales Analysis by Geographic Region: 2005-2006 (Nine Months Ended, September) (In US$ million)

Table 58: Annual Sales Analysis: 2004-2005 (In US$ million))

Table 59: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million)

Table 60: Annual Sales Analysis by Business Segment: 2004-2005 (In US$ million)

Table 61: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million)

Ethicon, Inc. (USA)

Closure Medical Corporation (USA)

36. Kuraray America Company (USA)

37. Lintec of America, Inc. (USA)

38. MAST Biosurgery, Inc. (USA)

39. Nerites Corporation (USA)

40. Plasto, Inc. (USA)

41. Procter & Gamble Company (USA)

Table 62: Half Yearly Sales Analysis: 2007 Vs. 2006 (H1) (In US$ million)

Table 63: Half Yearly Sales Analysis by Quarter: 2007 Vs. 2006 (H1) (In US$ million)

Table 64: Half Yearly Sales Analysis by Business Segment: 2007 Vs. 2006 (H1) (In US$ million)

Table 65: Annual Sales Analysis: 2006 Vs. 2005 (In US$ million)

Table 66: Annual Sales Analysis by Quarter: 2006 Vs. 2005 (In US$ million)

Table 67: Annual Sales Analysis by Business Segment: 2006 Vs. 2005 (In US$ million)

Procter & Gamble Health Care (USA)

42. Protein Polymer Technologies, Inc. (USA)

Table 68: Annual Sales Analysis: 2006 Vs. 2005 (In US$ thousands)

43. Pulpdent Corporation (USA)

44. Rohm and Haas Company (USA)

Table 69: Market Share by Business Segment: 2005 (% Breakdown of Value Sales)

Table 70: Market Share by Geographic Region: 2005 (% Breakdown of Value Sales)

Table 71: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September)(In US$ million)

Table 72: Nine Months Sales Analysis by Business Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 73: Nine Months Sales Analysis by Geographic Region: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 74: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 75: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 76: Annual Sales Analysis by Business Segment: 2005 Vs. 2004 (In US$ million)

Table 77: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

45. Rollprint Packaging Products, Inc. (USA)

46. Scapa North America (USA)

47. Schering-Plough Corporation (USA)

Table 78: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 79: Nine Months Sales Analysis by Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 80: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 81: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 82: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In US$ million)

Table 83: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

48. Smith & Nephew Wound Management (USA)

49. Sybron Dental Specialties, Inc. (USA)

Table 84: First Quarter Sales Analysis: 2005-2006 (In US$ million)

Table 85: First Quarter Sales Analysis by Segment: 2005-2006 (In US$ million)

Table 86: First Quarter Sales Analysis by Business Operation: 2005-2006 (In US$ million)

Table 87: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million)

Table 88: Annual Sales Analysis by Segment: 2004-2005 (In US$ million)

Table 89: Annual Sales Analysis by Business Operation: 2004-2005 (In US$ million)

Table 90: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million)

Kerr Corporation (USA)

50. Tangent Industries, Inc. (USA)

51. Tape-O Corporation (USA)

52. ThermoGenesis Corporation (USA)

Table 91: Nine Months Sales Analysis: 2007 Vs. 2006 (Nine Months Ended, March) (In US$ thousands)

Table 92: Annual Sales Analysis: 2006 Vs. 2005 (In US$ thousands)

Table 93: Annual Sales Analysis: 2006 Vs. 2005 (In US$ thousands)

53. TruMed Technologies, Inc. (USA)

54. United States Surgical - Syneture Division (USA)

Abstract

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