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Global Protein Therapeutics Market Analysis

Published by: RNCOS

Published: Sep. 1, 2007 - 150 Pages


Table of Contents


1. Analyst View

2. Global Therapeutic Proteins Market

2.1 Market Analysis

2.1.1 Market Size

2.1.2 Therapeutic Proteins Market vs Pharmaceutical Market

2.1.3 Market Segmentation

2.1.4 Future Outlook (2007-2010)

3. Industry Performance

3.1 Monoclonal Antibodies (mAb)

3.1.1 Market Size

3.1.2 By Application

3.1.2.1 Oncology Treatment

3.1.2.2 Immunologic & Inflammatory Diseases Treatment

3.1.2.3 Cardiovascular & Infectious Diseases Treatment

3.1.3 Key Geographical Markets

3.1.3.1 US

3.1.3.2 Europe

3.1.3.3 Japan

3.1.4 Key Players & Drugs

3.1.5 Industry Analysis

3.1.5.1 Drivers

3.1.5.2 Restraints

3.1.6 Future Outlook (2007-2011)

3.2 Erythropoietin (EPO)

3.2.1 Market Size

3.2.1.1 First Generation Erythropoietin

3.2.1.2 Second Generation Erythropoietin

3.2.2 By Application

3.2.2.1 Renal Anemia Treatment

3.2.2.2 Cancer Anemia Treatment

3.2.3 Key Geographical Markets

3.2.3.1 US

3.2.3.2 Europe

3.2.3.3 Japan

3.2.4 Key Players & Drugs

3.2.4.1 Erythropoietin Alpha

3.2.4.2 Erythropoietin Beta

3.2.4.3 Darbepoetin Alpha

3.2.5 Industry Analysis

3.2.5.1 Drivers

3.2.5.2 Restraints

3.2.6 Future Outlook (2007-2010)

3.3 Insulin

3.3.1 Market Size

3.3.2 By Application

3.3.2.1 Diabetes Treatment

3.3.3 Key Geographical Markets

3.3.3.1 India

3.3.3.2 China

3.3.3.3 US

3.3.3.4 Russia

3.3.3.5 Japan

3.3.3.6 Germany

3.3.3.7 Brazil

3.3.4 Key Players & Drugs

3.3.5 Industry Analysis

3.3.5.1 Drivers

3.3.5.2 Restraints

3.3.6 Future Outlook (2007-2010)

3.4 Interferon (IFN)

3.4.1 Market Size

3.4.1.1 Interferon Alpha

3.4.1.1.1 By Application

3.4.1.1.1.1 Hepatitis B Treatment

3.4.1.1.1.2 Hepatitis C Treatment

3.4.1.2 Interferon Beta

3.4.1.2.1 By Application

3.4.1.2.1.1 Multiple Sclerosis Treatment

3.4.2 Key Geographical Markets

3.4.2.1 US

3.4.2.2 Europe

3.4.2.2.1 Germany

3.4.2.3 Japan

3.4.3 Key Players & Drugs

3.4.3.1 Interferon Alpha

3.4.3.2 Interferon Beta

3.4.4 Industry Analysis

3.4.4.1 Drivers

3.4.4.2 Restraints

3.4.5 Future Outlook (2007-2011)

3.5 Human Growth Hormone (HGH)

3.5.1 Market Size

3.5.2 By Application

3.5.2.1 Pediatric Growth Hormone Deficiency Treatment

3.5.2.2 Adult Growth Hormone Deficiency Treatment

3.5.3 Key Geographical Markets

3.5.3.1 US

3.5.3.2 Europe & Japan

3.5.4 Key Players & Drugs

3.5.5 Industry Analysis

3.5.5.1 Drivers

3.5.5.2 Restraints

3.5.6 Future Outlook (2007-2010)

3.6 Blood Clotting Factor

3.6.1 Market Size

3.6.1.1 Recombinant Factor VIII

3.6.1.2 Recombinant Factor VIIa

3.6.1.3 Recombinant Factor IX

3.6.2 Key Players & Drugs

3.6.3 Industry Analysis

3.6.3.1 Drivers

3.6.3.2 Restraints

3.6.4 Future Outlook (2007-2010)

3.7 Follicle Stimulating Hormone (FSH)

3.7.1 Market Size

3.7.2 Key Players & Drugs

3.7.3 Industry Analysis

3.7.3.1 Drivers

3.7.3.2 Restraints

3.7.4 Future Outlook (2007-2010)

3.8 Granulocyte Colony Stimulating Factor (G-CSF)

3.8.1 Market Size

3.8.2 Key Players & Drugs

3.8.3 Industry Analysis

3.8.3.1 Drivers

3.8.3.2 Restraints

3.8.4 Future Outlook (2007-2010)

4. Industry Analysis

4.1 Drivers

4.1.1 Higher Efficacy than Traditional Drugs

4.1.2 High Rate of Approval

4.1.3 Ageing Population

4.1.4 Healthcare Insurance

4.2 Opportunities

4.2.1 Biogenerics

4.2.2 Contract Research

4.2.3 Drug Delivery Devices

4.2.4 Healthcare Insurance

4.2.5 Drug Packaging

4.3 Challenges

4.3.1 Immunogenicity

4.3.2 High R&D Cost

4.3.3 High Price

4.3.4 High Failure Rates in Phase-3 Clinical Trials

4.3.5 Insurance Reimbursements

4.3.6 Lack of Predictability in the Operating Environment

5. Key Players

5.1 Johnson & Johnson

5.2 Biogen Idec Inc.

5.3 Eli Lilly & Company

5.4 Novo Nordisk A/S

5.5 Sanofi-Aventis

5.6 Roche Group

5.7 Amgen Inc.

5.8 Genentech, Inc.

5.9 Merck Serono S.A

5.10 Genzyme Corporation


List of Figures:


Figure 2-1: Global - Therapeutic Proteins Market (in Billion US$), 2005 & 2006E

Figure 2-2: Global - Comparison of Therapeutic Proteins Market to Pharmaceutical Market (in Billion US$), 2005 & 2006

Figure 2-3: Global - Therapeutic Proteins Market by Segment (%), 2006

Figure 2-4: Global - Forecast for Therapeutic Proteins Market (in Billion US$), 2007-2010

Figure 2-5: Global - Forecast for Therapeutic Proteins Market by Segment (%), 2010

Figure 3-1: Global - Monoclonal Antibodies Market (in Billion US$), 2004-2006E

Figure 3-2: Global - Monoclonal Antibodies Market in Cancer Treatment (in Billion US$), 2001, 2003 & 2006E

Figure 3-3: Global - Monoclonal Antibodies Market in Rheumatoid Arthritis Treatment (in Million US$), 2003-2005

Figure 3-4: Global - Monoclonal Antibodies Market in Cardiovascular & Infectious Diseases Treatment (in Million US$), 2004

Figure 3-5: US - Monoclonal Antibodies Market (in Billion US$), 2005 & 2006E

Figure 3-6: US - Forecast for Monoclonal Antibodies Market (in Billion US$), 2007-2012

Figure 3-7: Europe - Monoclonal Antibodies Market (in Billion US$), 2004-2006E

Figure 3-8: Europe - Forecast for Monoclonal Antibodies Market (in Billion US$), 2007-2011

Figure 3-9: Europe - Forecast for Monoclonal Antibodies Market by Application (%), 2011

Figure 3-10: Japan - Monoclonal Antibodies Market (in Billion JPY), 2003-2006E

Figure 3-11: Japan - Forecast for Monoclonal Antibodies Market (in Billion JPY), 2007-2011

Figure 3-12: Global - Share of Key Players in Monoclonal Antibodies Market (%), 2005

Figure 3-13: Global - Top Selling Monoclonal Antibodies (in Million US$), 2006

Figure 3-14: Global - Number of New Cancer Cases (in Million), 2000 & 2020F

Figure 3-15: Global - Forecast for Monoclonal Antibodies Market (in Billion US$), 2007-2011

Figure 3-16: Global - Forecast for Monoclonal Antibodies Market by Application (%), 2011

Figure 3-17: Global - Erythropoietin Market (in Billion US$), 2005 & 2006

Figure 3-18: Global - First Generation Erythropoietin Market (in Million US$), 2005 & 2006

Figure 3-19: Global - First Generation Erythropoietin Alpha Market (in Million US$), 2005 & 2006

Figure 3-20: Global - First Generation Erythropoietin Beta Market (in Million US$), 2005 & 2006

Figure 3-21: Global - Second Generation Erythropoietin Market (in Million US$), 2005 & 2006

Figure 3-22: Global - Number of Dialysis Patients (in Million), 2003-2006E

Figure 3-23: Global - Breakup of Dialysis Patients by Region (%), 2004

Figure 3-24: Europe - Number of Dialysis Patients Treated & Not Treated by Erythropoietin (in ‘000), 2004

Figure 3-25: Europe - Erythropoietin & Untapped Erythropoietin Market (in Million Euro), 2004

Figure 3-26: Global - Number of Cancer Patients (in Million), 2003-2006E

Figure 3-27: Global - Breakup of Cancer Patients by Region (%), 2004

Figure 3-28: Europe - Breakup of Cancer Therapy (%), 2004

Figure 3-29: Europe - Number of Chemotherapy Patients Treated & Not Treated by Erythropoietin (in ‘000), 2004

Figure 3-30: Europe - Erythropoietin & Untapped Erythropoietin Market (in Million Euro), 2004

Figure 3-31: US - Share in Global Erythropoietin Market (%), 2005

Figure 3-32: Europe - Erythropoietin Market (in Billion US$), 2003-2006E

Figure 3-33: Europe - Forecast for Erythropoietin Market (in Billion US$), 2007-2011

Figure 3-34: Europe - Erythropoietin Market in Renal Anemia Treatment (in Million US$), 2004-2006E

Figure 3-35: Europe - Forecast for Erythropoietin Market in Renal Anemia Treatment (in Million US$), 2007-2011

Figure 3-36: Europe - Erythropoietin Market in Oncology Treatment (in Million US$), 2004-2006E

Figure 3-37: Europe - Forecast for Erythropoietin Market in Oncology Treatment (in Million US$), 2007-2011

Figure 3-38: Europe - First Generation Erythropoietin Patent* Expiry by Major Country

Figure 3-39: Japan - Erythropoietin Market (in Billion JPY), 2003-2006E

Figure 3-40: Global - Forecast for Erythropoietin Market (in Billion US$), 2007-2010

Figure 3-41: Europe - Forecast for Share of Oncology & Renal Anemia in Erythropoietin Market (%), 2016

Figure 3-42: Global - Insulin Market (in Billion US$), 2005 & 2006

Figure 3-43: India - Insulin Market (in Million US$), 2004-2007E

Figure 3-44: India - Share of Key Players in Insulin Market (%), 2004

Figure 3-45: China - Insulin Market (in Million US$), 2006-2009E

Figure 3-46: China - Share of Key Players in Insulin Market (%), 2005

Figure 3-47: US - Insulin Market (in Billion US$), 2002-2006E

Figure 3-48: US - Share of Key Players in Insulin Market (%), 2005

Figure 3-49: Russia - Insulin Market (in Million US$), 2005-2008E

Figure 3-50: Russia - Share of Key Players in Insulin Market (%), 2005

Figure 3-51: Russia - Insulin Market by Channel of Sales (%), 2005

Figure 3-52: Japan - Insulin Market (in Million US$), 2005-2008E

Figure 3-53: Japan - Share of Key Players in Insulin Market (%), 2006

Figure 3-54: Germany - Share of Insulin in Genetically Manufactured Pharmaceuticals Market (%), 2005

Figure 3-55: Brazil - Insulin Market (in Million US$), 2000, 2006 & 2010F

Figure 3-56: Global - Share of Key Players in Insulin Market (%), Q1 2005

Figure 3-57: Global - Share of Novo Nordisk in Major Insulin Markets (%), 2006

Figure 3-58: Global - Share of Insulin Market by Brand (%), 2006*

Figure 3-59: Global - Number of Diabetic Patients (in Million), 2006 & 2025F

Figure 3-60: Global - Forecast for Insulin Market (in Billion US$), 2007-2010

Figure 3-61: Global - Interferon Market (in Billion US$), 2005 & 2006

Figure 3-62: Global - Share of Interferon Market by Segment (%), 2006

Figure 3-63: Global - Interferon Alpha Market (in Billion US$), 2005 & 2006

Figure 3-64: Global - Forecast for Hepatitis B Treatment Market (in Billion US$), 2010-2015

Figure 3-65: Global - Hepatitis C Treatment Market (in Billion US$), 2005 & 2006

Figure 3-66: Global - Forecast for Hepatitis C Treatment Market (in Billion US$), 2007-2015

Figure 3-67: Global - Forecast for Share of Interferon in Hepatitis C Treatment Market (%), 2015

Figure 3-68: Global - Interferon Beta Market (in Billion US$), 2005 & 2006

Figure 3-69: Global - Multiple Sclerosis Treatment Market (in Billion US$), 2006 & 2016F

Figure 3-70: US - Interferon Market (in Billion US$), 2006*

Figure 3-71: Europe - Interferon Market (in Million US$), 2004

Figure 3-72: Germany - Interferon Market (in Million Euro), 2005

Figure 3-73: Japan - Interferon Market (in Billion JPY), 2004-2006E

Figure 3-74: Global - Forecast for Interferon Market (in Billion US$), 2007-2011

Figure 3-75: Global - Human Growth Hormone Market (in Billion US$), 2005 & 2006

Figure 3-76: US, Europe & Japan - Number of Patients with Pediatric Growth Hormone Deficiency (in ‘000), 2005

Figure 3-77: Global - Share of Growth Hormones in Treatment of Pediatric Short Stature (%), 2006

Figure 3-78: Global - Adult Growth Hormone Deficiency Market (in Million US$), 2006

Figure 3-79: Global - Breakup of Human Growth Hormone Market by Region (%), 2003

Figure 3-80: US - Human Growth Hormone Market (in Million US$), 2003, 2005E & 2006E

Figure 3-81: Japan & Europe - Human Growth Hormone Market (in Million US$), 2003

Figure 3-82: Global - Share of Key Players in Human Growth Hormone Market (%), 2006

Figure 3-83: Global - Forecast for Human Growth Hormone Market (in Billion US$), 2007-2010

Figure 3-84: Global - Blood Clotting Factor Market (in Billion US$), 2005 & 2006E

Figure 3-85: Global - Share of Blood Clotting Factor Market by Segment (%), 2006

Figure 3-86: Global - Share of Key Players in Blood Clotting Factor Market (%), 2006

Figure 3-87: Global - Forecast for Blood Clotting Factor Market (in Billion US$), 2007-2010

Figure 3-88: Global - Recombinant Follicle Stimulating Hormone Market (in Billion US$). 2005 & 2006

Figure 3-89: Global - Forecast for Recombinant Follicle Stimulating Hormone Market (in Billion US$), 2007-2010

Figure 3-90: Global - Granulocyte Colony Stimulating Factor Market (in Billion US$), June 2005 & June 2006

Figure 3-91: Global - Breakup of Granulocyte Colony Stimulating Factor Market by Region (%), 2006

Figure 3-92: Global - Share of Granulocyte Colony Stimulating Factor Market by Brand (%), 2006*

Figure 3-93: Global - Forecast for Granulocyte Colony Stimulating Factor Market (in Billion US$), 2007-2010

Figure 4-1: Global - Approval Rate for Biopharmaceuticals & Conventional Pharmaceuticals (%)

Figure 4-2: Global - Population in Age Group of 65 Years & Above by Region (%), 2000, 2015F & 2030F

Figure 4-3: US & EU - Forecast for Biogeneric Market by Segment (in Million US$), 2010

Figure 4-4: Global - Contract Research Organization Market (in Billion US$), 2006 & 2010F

Figure 4-5: Global - Forecast for Drug Delivery Market (in Billion US$), 2007-2009

Figure 4-6: US - Number of Uninsured People (in Million), 2005 & 2006E

Figure 4-7: Global - Comparison of Annual Cost of Biotech Drugs to Traditional Drugs (in US$), 2006

Figure 4-8: Global - Failure Rate in Phase-3 Clinical Trials of Biotech & Traditional Drugs (%)


List of Tables:


Table 3-1: Global - Key Players & Drugs in Erythropoietin Alpha Market by Sale (in Million US$), 2006

Table 3-2: Global - Key Players & Drugs in Erythropoietin Beta Market by Sale (in Million CHF), 2006

Table 3-3: Global - Key Players & Drugs in Darbepoetin Alpha Market by Sale (in Million US$), 2006

Table 3-4: India - Diabetic Patients in Age Group 20-79 (in ‘000), 2003

Table 3-5: India - Forecast for Diabetic Patients in Age Group 20-79 (in ‘000), 2025

Table 3-6: China - Diabetic Patients in Age Group 20-79 (in ‘000), 2003

Table 3-7: China - Forecast for Diabetic Patients in Age Group 20-79 (in ‘000), 2025

Table 3-8: US - Diabetic Patients in Age Group 20-79 (in '000), 2003

Table 3-9: US - Forecast for Diabetic Patients in Age Group 20-79 (in ‘000), 2025

Table 3-10: Russia - Diabetic Patients in Age Group 20-79 (in '000), 2003

Table 3-11: Russia - Forecast for Diabetic Patients in Age Group 20-79 (in '000), 2025

Table 3-12: Japan - Diabetic Patients in Age Group 20-79 (in '000), 2003

Table 3-13: Japan - Forecast for Diabetic Patients in 20-79 Age Group (in '000), 2025

Table 3-14: Germany - Diabetic Patients in Age Group 20-79 (in '000), 2003

Table 3-15: Germany - Forecast for Diabetic Patients in Age Group 20-79 (in '000), 2025

Table 3-16: Brazil - Diabetic Patients in Age Group 20-79 (in '000), 2003

Table 3-17: Brazil - Forecast for Diabetic Patients in Age Group 20-79 (in '000), 2025

Table 3-18: Global - Key Players & Drugs in Interferon Alpha Market by Sale (in Million US$), 2006

Table 3-19: Global - Key Players & Drugs in Interferon Beta Market by Sale (in Million US$), 2006

Table 3-20: Global - Key Players & Drugs in Human Growth Hormone Market by Sale (in Million US$), 2006

Table 3-21: Global - Key Players & Drugs in Blood Clotting Factor Market by Sale (in Million US$), 2006

Table 3-22: Global - Key Players & Drugs in Recombinant Follicle Stimulating Hormone Market by Sale (in Million US$), 2006

Table 4-1: US & Europe - Patent Expiry Dates for Recombinant Biologics

Table 5-1: Johnson & Johnson - Key Financials (in Million US$), 2004-2006

Table 5-2: Biogen Idec Inc. - Key Financials (in Million US$), 2004-2006

Table 5-3: Eli Lilly & Company - Key Financials (in Million US$), 2004-2006

Table 5-4: Novo Nordisk A/S - Key Financials (in Million US$), 2004-2006

Table 5-5: Sanofi-Aventis - Key Financials (in Million US$), 2004-2006

Table 5-6: Roche Group - Key Financials (in Million CHF), 2004-2006

Table 5-7: Amgen, Inc. - Key Financials (in Million US$), 2004-2006

Table 5-8: Genentech, Inc. - Key Financials (in Million US$), 2004-2006

Table 5-9: Merck Serono S.A - Key Financials (in Million US$), 2003-2005

Table 5-10: Genzyme Corporation - Key Financials (in Million US$), 2004-2006

Abstract

The latest market research report “Global Protein Therapeutics Market Analysis” by RNCOS provides an exhaustive view on the global protein therapeutics industry, examining and giving a detailed analysis of the various protein therapeutics used for disease prevention. The report discusses various aspects of the Protein Therapeutic Market, such as market size, area of applications and key geographical markets along with the drivers and restraints affecting the growth of each segment.

The Protein Therapeutic Market was valued in excess of US$ 57 Billion in 2006 and according to projections, it would grow at a CAGR 12.83% till 2010. The market is presently dominated by Monoclonal Antibodies and with double-digit growth projected for future, the segment is expected to bolster its dominant position. Insulin, Interferon Beta, G-CSF and coagulation factors are also exhibiting double-digit growth rates.

One of the biggest opportunity areas in the Protein Therapeutics Market will be in the field of Biogenerics, which is expected to create a multi-billion dollar market in future.

Key Findings
  • US is the largest market for therapeutic proteins in the world followed by Europe and Japan.
  • Insurance reimbursement is a major factor that decides the success of protein therapeutics.
  • Growth in protein therapeutic market will create new opportunities for the drug discovery Contract Research Organizations (CROs).
  • High expenditure on R&D and high rate of failure in phase-3 clinical trials remains a major challenge for the global protein therapeutics market.
  • Until recently, protein therapeutics faced little generic threat; however, this is likely to change in future with regulatory pathways for the approval of generics already present in Europe and Asia and to be introduced in US by 2009.
Key Issues and Facts Analyzed
  • Evaluation of past, current and future market trends.
  • Discussion about the major protein therapeutics and their markets.
  • Analysis of key geographical markets.
  • Analysis of various challenges and opportunities for the industry.
  • Future prospects of the various protein therapeutics segments.
  • Profile discussion of key players in this sector.
Key Players Analyzed
This section provides the overview, key facts, and financial information of prominent players in the global protein therapeutics market, such as Amgen, Genentech, Roche Group, Merck Serono S.A, Johnson & Johnson, Novo Nordisk A/S etc.

Research Methodology Used

Information Sources
Information has been sourced from credible sources including books, newspapers, trade journals, and white papers, industry portals, government agencies, trade associations, monitoring industry news and developments, and through access to more than 3000 paid databases.

Analysis Methods
The analysis methods include ratio analysis, historical trend analysis, linear regression analysis using software tools, judgmental forecasting, and cause and effect analysis.

For the purpose of this report, the following segments have been included in the Protein Therapeutics Market: Monoclonal antibodies, EPO, Interferon’s, Blood Clotting Factors, HGH, FSH, G-CSF and Insulin

The following currency conversion has been followed in the report:
1 US$ = Euros 0.73, JPY 121

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