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Gene Expression Reagents Markets

Published by: Trimark Publications

Published: Apr. 1, 2007 - 113 Pages


Table of Contents




1. Overview

1.1 Objectives of the Report

1.2 Methodology

1.3 Scope of the Report

1.4 Executive Summary



2. Gene Expression

2.1 The Genomics Revolution

2.2 Basic Principles of Gene Expression

2.3.1 Quantitative Real-Time PCR (qRT-PCR)

2.3.2 PCR Labeling Chemistries

2.3.3 TaqMan® Probes

2.3.4 SYBR® Green

2.4 Microarray Technology

2.5 Microarray Target Preparation and Hybridization

2.6 RNA Sample Preparation and Assessment



3. Gene Expression Reagents

3.1 Kit Format vs. Home-Brew Assays

3.2 Whole Product Solutions

3.3 Emerging Technologies



4. Market Environment

4.1 Institutional and Government Budgeting

4.2 Worldwide Investment in Genomics Technologies and Research

4.3 Industry Consolidation and Acquisitions



5. Market Drivers

5.1 Improved Assay Performance

5.2 Cost Effective Systems

5.3 Automation

5.4 Bioinformatics Solutions



6. Worldwide Market for Gene Expression Reagents

6.1 Life Science Research

6.2 Drug Discovery and Development, Molecular Diagnostics

6.3 Commercial Production

6.4 Gene Expression Market Size

6.4.1 Real-Time PCR Revenue

6.4.2 Commercial Microarray Revenue

6.4.3 RNA Sample Preparation Revenue

6.5 Gene Expression Reagent Market by Region

6.6 Users of Gene Expression Products

6.6.1 Core Laboratories

6.6.2 Consortia

6.6.3 Pharmaceutical and Biotechnology Companies

6.7 Affiliation

6.8 Job Function and Decision Makers



7. Key Applications

7.1 BioMarker Identification and Pharmacogenomics

7.2 Toxicogenomics

7.3 Molecular Diagnostics



8. Vendor and Product Selection

8.1 Product Adoption

8.2 Drivers for Product Switching



9. Leading Vendors



10. Marketing Strategies

10.1 e-Marketing and e-Commerce

10.2 Catalog 38

10.3 On-Site Cabinet Programs



11. Pricing Strategies

11.1 Price Elasticity

11.2 Strategies



12. Distribution Channels



13. Competitive Situation



14. Opportunities



15. Market Strategy Profiles, Leading and Selected Vendors

15.1 Applied Biosystems

15.1.1 Applera Corporation—Corporate History and Structure

15.1.2 Molecular Biology Technology and Products

15.1.3 Acquisitions, Partnerships and Collaborations, 2006

15.1.4 Product Portfolio Summary

15.1.5 Real-Time PCR/Genomics Products and Consumables

15.1.6 Real-Time PCR/Genomics New Product Introductions, 2006

15.1.7 End-Users

15.1.8 Distribution Channels

15.1.9 Competition—Gene Expression Products

15.1.10 Competitive Analysis

15.1.11 Business Model

15.2 Affymetrix

15.2.1 Corporate History and Structure

15.2.2 Technology

15.2.3 Partnerships and Collaborations

15.2.4 Product Portfolio Summary

15.2.5 Complementary Services

15.2.6 New Product Introductions

15.2.7 End-Users

15.2.8 Distribution Channels

15.2.9 Competition

15.2.10 Competitive Analysis

15.2.11 Business Model

15.3 Invitrogen

15.3.1 Corporate History and Structure

15.3.2 Technology

15.3.3 Acquisitions

15.3.4 Partnerships and Collaborations

15.3.5 Product Profile Summary

15.3.6 Gene Expression Product Portfolio

15.3.7 New Product Introductions

15.3.8 End-Users

15.3.9 Distribution Channels

15.3.10 Competition

15.3.11 Competitive Analysis

15.3.12 Business Model

15.4 Qiagen

15.4.1 Corporate History and Structure

15.4.2 Technology

15.4.3 Acquisitions, Partnerships and Collaborations

15.4.4 Collaborations and Partnerships

15.4.5 Product Portfolio Summary

15.4.6 Complementary Services

15.4.7 New Product Introductions

15.4.8 End-Users

15.4.9 Distribution Channels

15.4.10 Competition

15.4.11 Competitive Analysis

15.4.12 Business Model

15.5 GE Healthcare (Formerly Amersham Biosciences)

15.5.1 Corporate History and Structure

15.5.2 Technology

15.5.3 Product Portfolio Summary

15.5.4 Complementary Services

15.5.5 Genomics New Product Introductions

15.5.6 Amersham Biosciences End-Users

15.5.7 Distribution Channels

15.5.8 Competition

15.5.9 Competitive Analysis

15.5.10 Business Model

15.6 Stratagene

15.6.1 Corporate History and Structure

15.6.2 Technology

15.6.3 Acquisitions, Collaborations, Alliances and Partnerships

15.6.4 Product Portfolio Summary—Research Products Division

15.6.5 New Product Introductions

15.6.6 Complementary Services

15.6.7 End-Users

15.6.8 Distribution Channels

15.6.9 Competition

15.6.10 Competitive Analysis

15.6.11 Business Model



Appendix I: Leading Vendor’s Gene Expression Products

Appendix II: Gene Expression Product Groups

Appendix III: Companies Offering Gene Expression Products





LIST OF FIGURES



Figure 2.1: Gene Expression Process

Figure 2.2: qRT-PCR Workflow

Figure 2.3: Microarray Workflow

Figure 6.1: Gene Expression Market by Region

Figure 6.2: Researchers Using Gene Expression Technologies Worldwide, 2005

Figure 6.3: Distribution of Laboratory Workers by Organization in North America

Figure 6.4: Laboratory Job Function

Figure 6.5: Product Selection and Purchasing Decision Makers





LIST OF TABLES



Table 5.1: Microarray Analysis Cost per Sample

Table 5.2: Cost of qRT-PCR Research Reagents and Systems

Table 6.1: Five-Year Forecast—Gene Expression Reagents, Instruments

Table 6.2: RNA Sample Preparation Revenue

Table 6.3: Forecasted Annual Revenue—qRT-PCR, 2005-2010

Table 6.4: Forecasted Annual Revenue—Commercial Microarrays, Reagents, Instruments, 2005-2010

Table 6.5: Forecasted Annual Revenue—Gene Expression Reagents, Instruments, 2005-2010

Table 6.6: Forecasted Annual Revenue—RNA Sample Preparation, 2005-2010

Table 6.7: Projected Revenue Growth of Microarrays and Related Products

Table 6.8: Major Players’ Distribution of Revenue by Region, 2005

Table 6.9: Decision Makers Profile

Table 9.1: Major Vendors—Gene Expression Reagents and RNA Sample Preparation

Table 9.2: Vendors’ Key Statistics, 2005

Table 9.3: Vendors’ Technology and Products

Table 11.1: RNA Sample Preparation—Vendors Prices

Table 11.2: qPCR Kits—Vendor’s Prices

Table 11.3: Reverse Transcriptase—Vendor’s Prices

Table 12.1: Distribution Channels

Table 15.1: Applied Biosystems Revenue, 2005

Table 15.2: Affymetrix Revenue, 2005

Table 15.3: Invitrogen Revenue, 2005

Table 15.4: Qiagen Revenue, 2005

Table 15.5: GE Healthcare Revenue, 2005

Table 15.6: Stratagene Revenue, 2005



Abstract

The area of gene expression reagents is one of the newest and most important sectors of pharmaceutical and bioscience research and development. The term gene expression reagents refers to chemicals that are used in gene expression experiments that are performed to determine whether a particular gene is expressed—i.e., present—and in some cases at what levels, in a biological sample. The purpose of this TriMark Publications report is to describe the specific segments of the global gene expression reagents market. Within this area, the study covers those segments that are highly active in terms of innovation and growth. Specifically, this review examines the markets for gene expression reagents and small lab equipment all the way up to highly automated platforms. Emphasis is on those companies that are actively developing and marketing gene expression reagents for genomics research in the academic sector and the pharmaceutical, bioscience industry. This study concentrates on the laboratory reagent market segment and the companion gene expression reagents sector in the U.S. and around the world that use materials for genetic research. Particular attention is paid to those areas of the gene expression reagents sector that are showing the greatest growth or the most innovation.

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