Separation Systems for Commercial Biotechnology : Market Research Report

Separation Systems for Commercial Biotechnology

Published by: BCC Research

Published: Feb. 1, 2007 - 150 Pages

INTRODUCTION
EXECUTIVE SUMMARY: SUMMARY TABLE U.S. MARKET FORECAST FOR COMMERCIAL
OVERVIEW
INTRODUCTION TO THE COMMERCIAL PROTEIN SEPARATION: MARKET; TABLE 1 GLOBAL MANUFACTURE OF BULK PRODUCTS BY CHEMICAL SUBSTANCE USED IN BIOTECHNOLOGICAL PROCESSES, 2006 (TONS IN MILLIONS/EUROS PER KG)
COMMERCIAL SEPARATION SYSTEMS END-USE MARKETS: COMMERCIAL BIOTECHNOLOGY SEPARATION SYSTEMS ENDUSER DISTRIBUTION WITHIN THE U.S. MARKET; TABLE 2 U.S. DISTRIBUTION OF THE PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRY, BY REGION, 2006; FIGURE 1 BIOTECHNOLOGY ACTIVITY IN THE UNITED STATES
COMMERCIAL BIOTECH SEPARATION SYSTEMS MARKET: FIGURE 2 SEPARATION TECHNIQUES; TABLE 3 GLOBAL MARKET FORECAST FOR BIOTECHNOLOGY SEPARATIONS SYSTEMS INDUSTRY BY REGION, THROUGH 2011 ($ MILLIONS)
FIGURE 3 GLOBAL MARKET FORECAST FOR BIOTECHNOLOGY SEPARATION SYSTEMS INDUSTRY BY REGION, 2011 ($ MILLIONS): TABLE 4 GLOBAL MARKET VALUE OF SEPARATION SYSTEMS BY METHOD OF SEPARATION, 2006 ($ MILLIONS); FIGURE 4 GLOBAL SEPARATION SYSTEMS MARKET SHARES BY METHOD OF SEPARATION, 2006 (%); TABLE 5 U.S. MARKET SHARES: FORECAST FOR SEPARATION SYSTEMS BY METHOD OF SEPARATION, THROUGH 2011; FIGURE 5 U.S. MARKET SHARES: SEPARATION SYSTEMS MARKET SHARES BY METHOD OF SEPARATION, 2006 (%); FIGURE 5 (CONTINUED); TABLE 6 EUROPEAN MARKET SHARES: FORECAST FOR SEPARATION SYSTEMS BY METHOD OF SEPARATION, THROUGH 2011 ($ MILLIONS); FIGURE 6 EUROPEAN SEPARATION SYSTEMS MARKET SHARES BY METHOD OF SEPARATION, 2006 (%); TABLE 7 REST OF WORLD FORECAST FOR SEPARATION SYSTEMS BY METHOD OF SEPARATION, THROUGH 2011 ($ MILLIONS); FIGURE 7 REST OF THE WORLD SEPARATION SYSTEM MARKET SHARES BY METHOD OF SEPARATION, 2006; TABLE 8 COMPETITIVE STRUCTURE, 2006; OVERVIEW OF GLOBAL SEPARATION SYSTEMS MARKET SHARE ANALYSIS; FIGURE 8 GLOBAL MARKET SEPARATION SYSTEMS MARKET SHARES BY KEY PLAYER, 2006 (%)
CENTRIFUGATION SYSTEMS IN BIOTECHNOLOGY: TABLE 9 BIOTECHNOLOGICAL PROCESSES AND CHEMICALS USED; TABLE 10 PRICE OF CENTRIFUGATION SYSTEMS EQUIPMENT, 2006; TABLE 11 GLOBAL MARKET FORECAST FOR CENTRIFUGATION SEPARATION SYSTEMS BY REGION, THROUGH 2011 ($ MILLIONS); FIGURE 9 GLOBAL MARKET SHARES OF CENTRIFUGATION SEPARATION SYSTEMS BY REGION, 2004-2011 ($ MILLIONS); FIGURE 10 GLOBAL MARKET SHARES OF KEY PLAYERS IN THE CENTRIFUGATION SEPARATION SYSTEMS MARKET, 2006 (%)
LIQUID CHROMATOGRAPHY IN BIOTECHNOLOGY: LIQUID CHROMATOGRAPHY IN BIOTECHNOLOGY RECENT DEVELOPMENTS IN THE LIQUID CHROMATOGRAPHY MARKET; TABLE 12 PRODUCTS TECHNOLOGY IN CHROMATOGRAPHY BY COMPANY, 2006; FUTURE TRENDS; APPLICATIONS OF LIQUID CHROMATOGRAPHY IN THE; COST DRIVERS OF LIQUID CHROMATOGRAPHY IN THE BIOTECH INDUSTRY; TABLE 13 PRICE OF CHROMATOGRAPHY EQUIPMENT, 2006 ($) MARKET ANALYSIS OF GLOBAL LIQUID CHROMATOGRAPHY BIOTECH INDUSTRY THROUGH 2011; TABLE 14 GLOBAL MARKET FORECAST FOR LIQUID CHROMATOGRAPHY SYSTEMS BY REGION, THROUGH 2011; FIGURE 11 GLOBAL MARKET FORECAST FOR LIQUID CHROMATOGRAPHY SEPARATION SYSTEMS BY REGION, 2004-2011 ($ MILLIONS); TABLE 15 KEY PLAYERS IN THE CHROMATOGRAPHY SEPARATION SYSTEMS MARKET; FIGURE 12 GLOBAL LIQUID CHROMATOGRAPHY SEPARATION SYSTEMS MARKET SHARES BY KEY PLAYER, 2006 (%)
ELECTROPHORESIS IN BIOTECHNOLOGY: TABLE 16 PRICE OF ELECTROPHORESIS EQUIPMENT, 2006; TABLE 17 GLOBAL MARKET FORECAST FOR ELECTROPHORESIS SYSTEMS BY REGION, THROUGH 2011 ($ MILLIONS); FIGURE 13 GLOBAL MARKET FORECAST FOR ELECTROPHORESIS SYSTEMS BY REGION, 2004-2011 ($ MILLIONS); FIGURE 14 GLOBAL ELECTROPHORESIS MARKET SHARE BY KEY PLAYER, 2006 (%)
MEMBRANE FILTRATION IN BIOTECHNOLOGY
NICHE METHODS OF SEPARATION IN BIOTECHNOLOGY: TABLE 21 GLOBAL MARKET FORECAST FOR NICHE SEPARATION SYSTEMS BY REGION, THROUGH 2011 ($ MILLIONS); FIGURE 17 GLOBAL MARKET FORECAST FOR NICHE SEPARATION SYSTEMS BY REGION, 2004-2011 ($ MILLIONS); FIGURE 18 GLOBAL MARKET SHARE OF NICHE SEPARATION SYSTEMS BY KEY PLAYER, 2006 (%)
COMPANY PROFILES
PATENT ANALYSIS FOR THE COMMERCIAL BIOTECHNOLOGY SEPARATIONS MARKET: TABLE 22 PERCENTAGE OF DESIGN PATENTS RECORDED AGAINST TOTAL PATENTS FOUND IN SEARCH, 1996-2006; FIGURE 19 PATENTS* FILED ANNUALLY FOR BIOTECHNOLOGY SEPARATION SYSTEMS INCLUDING DESIGN AND TECHNOLOGY INNOVATION, DESIGN PATENTS VS TOTAL PATENTS 1996-2006; FIGURE 20 GEOGRAPHIC ORIGIN OF DESIGN PATENT APPLICATIONS, 1996-2006 (%); TABLE 23 TOTAL GLOBAL DESIGN PATENTS FILED BY PATENT HOLDER OR ASSIGNEE (PATENTS ISSUED AND PATENT APPLICATIONS), 1996-2006; FIGURE 21 SEPARATION SYSTEMS IN COMMERCIAL BIOTECHNOLOGY, GLOBAL DESIGN PATENTS FILED, 1996-2006 (%); TABLE 24 GLOBAL PATENTS BY TYPE OF SEPARATION, 1996-2006; FIGURE 22 GLOBAL PATENTS BY TYPE OF SEPARATION, 1996-2006; FIGURE 23 PROJECTED GLOBAL FUTURE PATENT APPROVALS, SEPARSATION SYSTEMS IN COMMERCIAL BIOTECHNOLOGY, 2006-2008 (%); TABLE 25 GLOBAL CHROMATOGRAPHY PATENTS; TABLE 25 (CONTINUED); TABLE 26 PENDING GLOBAL CHROMATOGRAPHY PATENT APPLICATIONS; TABLE 26 (CONTINUED); TABLE 27 MEMBRANE FILTRATION PATENTS; TABLE 27 (CONTINUED); TABLE 28 PENDING MEMBRANE FILTRATION PATENT APPLICATIONS; TABLE 28 (CONTINUED); TABLE 29 ELECTROPHORESIS PATENTS; TABLE 30 PENDING ELECTROPHORESIS PATENT APPLICATIONS
APPENDIX
LIST OF TABLES
SUMMARY TABLE U.S. MARKET FORECAST FOR COMMERCIAL BIOTECH SEPARATION SYSTEMS BY METHOD OF SEPARATION, THROUGH 2011 ($ MILLIONS)
TABLE 1 GLOBAL MANUFACTURE OF BULK PRODUCTS BY CHEMICAL SUBSTANCE USED IN BIOTECHNOLOGICAL PROCESSES, 2006 (TONS IN MILLIONS/EUROS PER KG)
TABLE 2 U.S. DISTRIBUTION OF THE PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRY, BY REGION, 2006
TABLE 3 GLOBAL MARKET FORECAST FOR BIOTECHNOLOGY SEPARATIONS SYSTEMS INDUSTRY BY REGION, THROUGH ($ MILLIONS)
TABLE 4 GLOBAL MARKET VALUE OF SEPARATION SYSTEMS BY METHOD OF SEPARATION, 2006 ($ MILLIONS)
TABLE 5 U.S. MARKET SHARES: FORECAST FOR SEPARATION SYSTEMS BY METHOD OF SEPARATION, THROUGH 2011
TABLE 6 EUROPEAN MARKET SHARES: FORECAST FOR SEPARATION SYSTEMS BY METHOD OF SEPARATION, THROUGH 2011 ($ MILLIONS)
TABLE 7 REST OF WORLD FORECAST FOR SEPARATION SYSTEMS BY METHOD OF SEPARATION, THROUGH 2011 ($ MILLIONS)
TABLE 8 COMPETITIVE STRUCTURE, 2006
TABLE 9 BIOTECHNOLOGICAL PROCESSES AND CHEMICALS USED
TABLE 10 PRICE OF CENTRIFUGATION SYSTEMS EQUIPMENT, 2006
TABLE 11 GLOBAL MARKET FORECAST FOR CENTRIFUGATION SEPARATION SYSTEMS BY REGION, THROUGH 2011 ($ MILLIONS)
TABLE 12 PRODUCTS TECHNOLOGY IN CHROMATOGRAPHY BY COMPANY, 2006
TABLE 13 PRICE OF CHROMATOGRAPHY EQUIPMENT, 2006 ($)
TABLE 14 GLOBAL MARKET FORECAST FOR LIQUID CHROMATOGRAPHY SYSTEMS BY REGION, THROUGH 2011
TABLE 15 KEY PLAYERS IN THE CHROMATOGRAPHY SEPARATION SYSTEMS MARKET
TABLE 16 PRICE OF ELECTROPHORESIS EQUIPMENT, 2006
TABLE 17 GLOBAL MARKET FORECAST FOR ELECTROPHORESIS SYSTEMS BY REGION, THROUGH 2011 ($ MILLIONS)
TABLE 18 CLASSES OF FILTRATION BY PORE SIZE AND APPLICATION
TABLE 19 PRICE OF EQUIPMENT IN MEMBRANE FILTRATION, 2006
TABLE 20 GLOBAL MARKET FORECAST FOR MEMBRANE FILTRATION SYSTEMS BY REGION, THROUGH 2011 ($ MILLIONS)
TABLE 21 GLOBAL MARKET FORECAST FOR NICHE SEPARATION SYSTEMS BY REGION, THROUGH 2011 ($ MILLIONS)
TABLE 22 PERCENTAGE OF DESIGN PATENTS RECORDED AGAINST TOTAL PATENTS FOUND IN SEARCH, 1996-2006
TABLE 23 TOTAL GLOBAL DESIGN PATENTS FILED BY PATENT HOLDER OR ASSIGNEE (PATENTS ISSUED AND PATENT APPLICATIONS), 1996-2006
TABLE 24 GLOBAL PATENTS BY TYPE OF SEPARATION, 1996-2006
TABLE 25 GLOBAL CHROMATOGRAPHY PATENTS
TABLE 26 PENDING GLOBAL CHROMATOGRAPHY PATENT APPLICATIONS
TABLE 27 MEMBRANE FILTRATION PATENTS
TABLE 28 PENDING MEMBRANE FILTRATION PATENT APPLICATIONS
TABLE 29 ELECTROPHORESIS PATENTS
TABLE 30 PENDING ELECTROPHORESIS PATENT APPLICATIONS
LIST OF FIGURES
SUMMARY FIGURE A U.S. MARKET FORECAST FOR COMMERCIAL BIOTECH SEPARATION SYSTEMS BY METHOD OF SEPARATION, 2004-2011 ($ MILLIONS)
SUMMARY FIGURE B U.S. MARKET SHARES OF COMMERCIAL BIOTECH SEPARATION SYSTEMS BY METHOD OF SEPARATION, 2006 (%) v
FIGURE 1 BIOTECHNOLOGY ACTIVITY IN THE UNITED STATES
FIGURE 2 SEPARATION TECHNIQUES
FIGURE 3 GLOBAL MARKET FORECAST FOR BIOTECHNOLOGY SEPARATION SYSTEMS INDUSTRY BY REGION, 2011 ($ MILLIONS)
FIGURE 4 GLOBAL SEPARATION SYSTEMS MARKET SHARES BY METHOD OF SEPARATION, 2006 (%)
FIGURE 5 U.S. MARKET SHARES: SEPARATION SYSTEMS MARKET SHARES BY METHOD OF SEPARATION, 2006 (%)
FIGURE 6 EUROPEAN SEPARATION SYSTEMS MARKET SHARES BY METHOD OF SEPARATION, 2006 (%)
FIGURE 7 REST OF THE WORLD SEPARATION SYSTEM MARKET SHARES BY METHOD OF SEPARATION, 2006
FIGURE 8 GLOBAL MARKET SEPARATION SYSTEMS MARKET SHARES BY KEY PLAYER, 2006 (%)
FIGURE 9 GLOBAL MARKET SHARES OF CENTRIFUGATION SEPARATION SYSTEMS BY REGION, 2004-2011 ($ MILLIONS)
FIGURE 10 GLOBAL MARKET SHARES OF KEY PLAYERS IN THE CENTRIFUGATION SEPARATION SYSTEMS MARKET, 2006 (%)
FIGURE 11 GLOBAL MARKET FORECAST FOR LIQUID CHROMATOGRAPHY SEPARATION SYSTEMS BY REGION, 2004-2011 ($ MILLIONS)
FIGURE 12 GLOBAL LIQUID CHROMATOGRAPHY SEPARATION SYSTEMS MARKET SHARES BY KEY PLAYER, 2006 (%)
FIGURE 13 GLOBAL MARKET FORECAST FOR ELECTROPHORESIS SYSTEMS BY REGION, 2004-2011($ MILLIONS)
FIGURE 14 GLOBAL ELECTROPHORESIS MARKET SHARE BY KEY PLAYER, 2006 (%)
FIGURE 15 GLOBAL MARKET FORECAST FOR MEMBRANE FILTRATION SYSTEMS BY REGION, 2004-2011 ($ MILLIONS)
FIGURE 16 GLOBAL MARKET SHARE OF MEMBRANE FILTRATIONS BY KEY PLAYER, 2006 (%)
FIGURE 17 GLOBAL MARKET FORECAST FOR NICHE SEPARATION SYSTEMS BY REGION, 2004-2011 ($ MILLIONS)
FIGURE 18 GLOBAL MARKET SHARE OF NICHE SEPARATION SYSTEMS BY KEY PLAYER, 2006 (%)
FIGURE 19 PATENTS FILED ANNUALLY FOR BIOTECHNOLOGY SEPARATION SYSTEMS INCLUDING DESIGN AND TECHNOLOGY INNOVATION, DESIGN PATENTS VS TOTAL PATENTS 1996-2006
FIGURE 20 GEOGRAPHIC ORIGIN OF DESIGN PATENT APPLICATIONS, 1996-2006 (%)
FIGURE 21 SEPARATION SYSTEMS IN COMMERCIAL BIOTECHNOLOGY, GLOBAL DESIGN PATENTS FILED, 1996-2006 (%)
FIGURE 22 GLOBAL PATENTS BY TYPE OF SEPARATION, 1996-2006
FIGURE 23 PROJECTED GLOBAL FUTURE PATENT APPROVALS, SEPARSATION SYSTEMS IN COMMERCIAL BIOTECHNOLOGY, 2006-2008 (%)

Abstract

REPORT HIGHLIGHTS
- The U.S. market for protein separation systems is estimated to be valued at almost $3.0 billion in the base year, 2006. This market is expected to grow with an average annual growth rate (AAGR) of 11.1% and cross the $5.0 billion by the year 2011.

- The liquid chromatography market was $944 million in 2004 and will rise to more than $1.1 billion in the year 2006. This market has been showing exceptional growth due to its ability to separate large molecules before major analysis. This market is expected to reach $2.1 billion by 2011, an AAGR of 13.0%.

- The membrane filtration segment is valued at $538 million in year 2006 with an estimated growth of 10.8% and is predicted to grow to $898 million in year 2011. Though the capital costs involved in membrane filtration are higher than chemical treatments, the system increases energy and utilizes less company space as compared to chemical processes. This enables companies to reduce costs by upwards of 65%.

INTRODUCTION

BCC Research's goal in conducting this study was to determine the present status of the worldwide protein separation market and to evaluate its potential over the 5-year period from 2006 to 2011. In assessing this market, all of the important segments were considered. In addition, a review of the market potential for emerging technologies in the protein separation market was conducted

With increasing R&D conducted in developing new drugs in the pharmaceutical and biotechnology sectors, the importance of protein separation is evident. Thus, BCC Research sought to determine which industries use protein separation techniques and to assess which of the techniques are poised for growth.

SCOPE OF STUDY

This report contains:
- The U.S. market for separation systems of commercial biotechnology broken down into five segments: liquid chromatography, centrifugation, membrane filtration, electrophoresis and niche separations
- Market trends, historical data, and five-year projections to 2011
- A discussion and review of important technology and the latest technological advancements in the industry
- Lists and analysis of important and upcoming patents
- Profiles for the top players within the industry.

METHODOLOGY

BCC Research presents an analysis by each protein separation technique used for biotechnology application considering the base year 2006. Estimated values are based on what manufacturers have paid in undepreciated dollars. Analysis of potential applications for technology and forecast unit shipments for 2006 and 2011 were based on survey research.

INFORMATION SOURCES

The major sources of information for this study have been the primary research done by interviewing the majority of the key players in this industry and secondary research compiled from the Internet, company websites, current financial and trade information, and government sources.

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Separation Systems for Commercial Biotechnology

Table of Contents

Abstract