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Nanotechnology in Health Care

Published by: Freedonia Group Inc

Published: Feb. 1, 2007


Table of Contents


INTRODUCTION

I. EXECUTIVE SUMMARY

II. MARKET ENVIRONMENT

General

Macroeconomic Outlook

Demographic Trends

Health Care Trends

Medical Conditions

Chronic Conditions

Acute Conditions

Health Insurance & Reimbursement

National Health Expenditures

Medical Providers

Hospitals

Outpatient Facilities

Physicians

Dentists

Other Health Care Providers

Patient Activity

Surgical Procedures

Outpatient Visits

Diagnostic Tests

Medical Product Demand

Pharmaceuticals

Diagnostic Products

In Vitro Diagnostic (IVD) Products

In Vivo Imaging Agents

Medical Supplies & Devices

III. NANOTECHNOLOGY OVERVIEW

General

Product Groups

Regulatory Trends

Pharmaceuticals

Diagnostic Products

Medical Supplies & Devices

Current Good Manufacturing Practices (cGMPs)

Investment Environment

International Markets

IV. NANOMATERIALS

General

Monoclonal Antibodies

DNA Materials

Nanoparticles

Nanotubes & Nanowires

Dendrimers

Fullerenes

Quantum Dots

Other Nanomaterials

V. NANOMEDICINES

General

Product Groups

Monoclonal Antibodies

Marketed Products

Products in Development

Polymer-Based Nanomedicines

Marketed Products

Developmental Activities

Other Nanomedicines

Nanocrystal Therapies

Liposomes

Marketed Products

Products in Development

All Other Nanomedicines

Marketed Products

Products in Development

VI. NANODIAGNOSTICS

General

In Vitro Diagnostics

Monoclonal Antibodies

Immunological Reagents & Test Kits

Immunohematology

Cellular Analysis

Research Reagents

DNA Testing Materials

Amplified DNA Probes

Direct DNA Probes

DNA Microarrays

Other DNA Testing Materials

In Vivo Diagnostics

MRI Imaging Agents

Advanced Magnetics

Kereos

Other Development Stage Compounds

Other Diagnostic Imaging Agents

VII. NANOTECH MEDICAL SUPPLIES & DEVICES

General

Orthopedic Products

Bone Cement

Bone Substitutes

Orthopedic Implants

Wound Management Products

Wound Closures

Wound Dressings

Dental Products

Surgical Products

Ophthalmic Products

Other Nanotechnology Medical Supplies & Devices

Disinfectants

Cardiac Implants

Cochlear Implants

Catheters

Neuron Regenerators

Artificial Skin

VIII. APPLICATIONS

General

Cancer

Epidemiological Trends

Nanomedicines

Diagnostics

Central Nervous System Conditions

Epidemiological Trends

Nanomedicines

Diagnostics

Medical Supplies & Devices

Infective & Parasitic Conditions

Epidemiological Trends

Nanomedicines

Diagnostics

Cardiovascular Conditions

Epidemiological Trends

Nanomedicines

Diagnostics

Medical Supplies & Devices

Other Applications

IX. INDUSTRY STRUCTURE

General

Market Share

Competitive Strategies

Licensing Agreements

Research & Development

Marketing & Distribution

Manufacturing

Company Profiles

Abbott Laboratories

Abraxis BioScience Incorporated

Access Pharmaceuticals Incorporated

Advanced Magnetics Incorporated

Advion BioSciences Limited

Alnis BioSciences Incorporated

Altair Nanotechnologies Incorporated

ALZA Corporation, see Johnson & Johnson

American BioScience, see Abraxis BioScience

American Pharmaceutical Partners, see Abraxis BioScience

Amgen Incorporated

Angstrom Medica Incorporated

Arrowhead Research Corporation

AstraZeneca plc

Avidimer Therapeutics Incorporated

Baxter International Incorporated

Bayer AG

BioDelivery Sciences International

BioForce Nanosciences Holdings Incorporated

Biogen Idec Incorporated

Biophan Technologies Incorporated

BioSante Pharmaceuticals Incorporated

BioTrove Incorporated

Bristol-Myers Squibb Company

C Sixty, see Carbon Nanotechnologies

Carbon Nanotechnologies Incorporated

CritiTech Incorporated

Crystalplex Corporation

CytImmune Sciences Incorporated

Danaher Corporation

Dendritic NanoTechnologies, see Starpharma Holdings

Dow Chemical Company

Elan Corporation plc

Enzon Pharmaceuticals Incorporated

eSpin Technologies Incorporated

Ferro Corporation

Flamel Technologies SA

GeneFluidics Incorporated

Genentech Incorporated

Health Plus International Incorporated

Improvita Health Products Incorporated

Insert Therapeutics, see Arrowhead Research

International Business Machines Corporation

Intradigm Corporation

Introgen Therapeutics Incorporated

Invitrogen Corporation

Johnson & Johnson

Kerr Corporation, see Danaher Corporation

Lavipharm Corporation

Luna Innovations Incorporated

Mallinckrodt, see Tyco International

Merck & Company Incorporated

Mersana Therapeutics Incorporated

NanoBio Corporation

NanoBioMagnetics Incorporated

NanoBioTec GmbH

Nanobiotix SA

NanoCarrier Company Limited

NanoCure Corporation, see Avidimer Therapeutics

NanoDel Technologies GmbH

Nanodisc Incorporated

Nanogen Incorporated

NanoHorizons Incorporated

NanoInk Incorporated

NanoLab

NanoMaterials Technology Pte Limited

NanoMed Pharmaceuticals Incorporated

Nanomix Incorporated

Nanopharma Corporation, see Mersana Therapeutics

Nanoplex Technologies, see Oxonica Limited

Nanospectra Biosciences Incorporated

Nanosys Incorporated

Nektar Therapeutics

Novagali Pharma SA

Novavax Incorporated

NUCRYST Pharmaceuticals Corporation

Ortho Biotech Products, see Johnson & Johnson

Orthovita Incorporated

Oxonica Limited

Pfizer Incorporated

PharmaSol GmbH

pSivida Limited

Quantum Dot, see Invitrogen Corporation

Roche Holding Limited

Salvona LLC

Sensatex Incorporated

Siemens AG

SkyePharma plc

Smiths Group plc

Soliqs, see Abbott Laboratories

Spire Corporation

Starpharma Holdings Limited

Sybron Dental Specialties, see Danaher

Tailored Materials Corporation Incorporated

Teva Pharmaceutical Industries Limited

3M Company

Triton BioSystems Incorporated

Tyco International Limited

Wyeth

LIST OF TABLES

SECTION I -- EXECUTIVE SUMMARY

Summary Table

SECTION II -- MARKET ENVIRONMENT

1 Macroeconomic Indicators

2 Population by Age Group

3 Medical Conditions by Duration & Type

4 National Health Expenditures by Type

5 Selected Medical Providers by Type

6 Selected Patient Activity by Type

7 Medical Product Demand by Type

8 Pharmaceutical Demand by Therapeutic Class

9 Diagnostic Product Demand by Type

SECTION III -- NANOTECHNOLOGY OVERVIEW

1 Nanotechnology Medical Product Demand by Type

2 R&D Investment in Nanotechnology Medical Products

SECTION V -- NANOMEDICINES

1 Nanomedicine Demand by Therapeutic Class

2 Nanomedicine Demand by Product Group

3 Therapeutic Monoclonal Antibody Demand

4 Therapeutic Monoclonal Antibodies Approved for US Sale

5 Therapeutic Monoclonal Antibodies -- US Sales by Product, 2001 & 2006

6 Polymer-Based Nanomedicine Demand

7 Polymer-Based Nanomedicines Approved for US Sale

8 Polymer-Based Nanomedicines -- US Sales by Product, 2001 & 2006

9 Other Nanomedicine Demand

10 Nanocrystal Medicines Approved for US Sale

11 Liposomal Therapies Approved for US Sale

12 Other Nanomedicines Approved for US Sale

SECTION VI -- NANODIAGNOSTICS

1 Nanotechnology-Based Diagnostic Product Demand by Segment

2 Nanotechnology In Vitro Diagnostic Product Demand by Type

3 Monoclonal Antibody-Based Diagnostic Product Demand by Type

4 Monoclonal Antibody-Based Immunological Reagent & Test Kit Demand

5 Monoclonal Antibody-Based Immunohematology Reagent & Test Kit Demand

6 Monoclonal Antibody-Based Cellular Analysis Reagent & Test Kit Demand

7 Monoclonal Antibody-Based Research Reagent Demand

8 DNA Testing Material Demand by Type

9 Amplified DNA Probe Demand

10 Direct DNA Probe Demand

11 DNA Microarray Demand

12 Other DNA Testing Material Demand by Type

13 Nanotechnology In Vivo Diagnostic Product Demand

SECTION VII -- NANOTECH MEDICAL SUPPLIES & DEVICES

1 Nanotechnology Medical Supply & Device Demand by Product Group

2 Nanotechnology Orthopedic Product Demand

3 Nanopolymer Bone Cement Demand

4 Nanomaterial Bone Substitute Demand

5 Nanotechnology Orthopedic Implant Demand by Type

6 Nanotechnology Wound Management Product Demand

7 Nanotechnology Wound Closure Demand

8 Nanotechnology Wound Dressing Demand

9 Nanotechnology Dental Product Demand

10 Nanotechnology Surgical Product Demand

11 Nanotechnology Ophthalmic Product Demand

12 Other Nanotechnology Medical Supply & Device Demand

SECTION VIII -- APPLICATIONS

1 Nanotechnology Medical Product Demand by Application

2 Nanotechnology Cancer Product Demand

3 Nanotechnology Central Nervous System Product Demand

4 Nanotechnology Product Demand for Infective & Parasitic Conditions

5 Nanotechnology Cardiovascular Product Demand

6 Nanotechnology Medical Product Demand in Other Applications by Product Class & Type

SECTION IX -- INDUSTRY STRUCTURE

1 Selected Cooperative Agreements

LIST OF CHARTS

SECTION III -- NANOTECHNOLOGY OVERVIEW

1 Nanotechnology Medical Product Demand by Type, 2011

SECTION V -- NANOMEDICINES

1 Nanomedicine Demand by Therapeutic Class, 2011

2 Nanomedicine Demand by Product Group, 2011

SECTION VI -- NANODIAGNOSTICS

1 Nanodiagnostics Demand by Product Group, 2011

SECTION VII -- NANOTECH MEDICAL SUPPLIES & DEVICES

1 Nanotech Medical Supply & Device Demand by Product Group, 2011

SECTION VIII -- APPLICATIONS

1 Nanotechnology Medical Product Demand by Application, 2011

SECTION IX -- INDUSTRY STRUCTURE

1 Nanotechnology Medical Product Market Share, 2006

Abstract

US demand to rise over 17% annually through 2011
US demand for nanotechnology health care products will grow over 17 percent per year to $50 billion in 2011. Afterwards, the increasing flow of new nanomedicines, nanodiagnostics, and nanotech-based medical supplies and devices into the US marketplace will boost demand to $107 billion in 2016 and $225 billion in 2021. The critical need for new or improved therapies for many medical conditions will promote the adaptation of nanotechnology to an expanding number of pharmaceuticals. The total market for nanomedicines will command strong growth over the long term, rising to $41 billion in 2011, $84 billion in 2016 and $175 billion in 2021. Treatments based on humanized monoclonal antibodies, nanopolymers and nanoproteins will drive gains, with compounds for cancer, neurological disorders, viral infections and ischemic heart diseases leading new product introductions and growth opportunities. Eventually, pharmaceutical applications of nanotechnology will extend into all major therapeutic classes, encompassing numerous formulations and delivery systems.

Nanodiagnostics to grow 13% per year through 2011
Advances in nanotechnology will also contribute significant improvements to the quality and performance of medical diagnostic products. Nanosized labels, probes and biosensors will greatly enhance the speed, accuracy, capabilities and cost-effectiveness of in vitro diagnostic testing, drug discovery and medical research procedures. Nanoparticle formulations of superparamagnetic iron oxide, gadolinium, perfluorocarbon and specialty polymers will broaden in vivo imaging capabilities by enabling the detection of tumors, plaque, genetic defects and other disease states at much earlier stages and with lower, safer concentrations of injected compounds. Reflecting these advantages and new offerings, demand for nanodiagnostic products is projected to increase over 13 percent per year to 2011 and continue rising at a double digit annual pace through 2021.

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