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Forteo: A Case Study in Launching a Breakthrough Therapy in a Saturated Market

Published by: Decision Resources

Published: Oct. 30, 2006 - 16 Pages

Price reduced due to age.

Table of Contents


Executive Summary

Strategic Considerations

Stakeholder Implications

Introduction

An Overview of Osteoporosis

Disease Description, Prevalence, and Economic Burden

Current Treatments

Bisphosphonates

SERMs

Osteoporosis Market in 2005

Case Study: Forteo

Forteo's Development and Approval

Forteo's Launch and Early Performance

The Outlook for Forteo

What Can Be Learned from Forteo?

Tables

1. Leading Therapies for the Treatment of Osteoporosis

2. Factors Limiting the Use of Forteo

Figures

1. Diagram of Bone Remodeling

2. Targets for Current Drugs in the Bone Remodeling Process

3. Market Share of Leading Drug Classes, 2005

4. Quarterly Sales of Forteo, 2002 to 2006

Abstract

The osteoporosis market has grown nearly 20% per year since 2000, presenting many opportunities for drug manufacturers. However, several effective, well-established, and reasonably priced agents dominate the market. Even novel therapies satisfying a distinct need face tremendous challenges when launched in this competitive arena.

Get the Answers You Need to Shape Your Strategy
Eli Lilly's bone-building drug Forteo (teriparatide) was a promising breakthrough treatment for osteoporosis that achieved disappointing sales and relatively low acceptance among patients and physicians. Why did Forteo fail to meet early expectations for its use?

Several issues during Forteo's development phase greatly affected its launch and initial uptake. What are some problems that can hinder the uptake of a breakthrough therapy? What lessons can be learned from Forteo's development and launch?

Even an effective novel agent may face challenges when placed in a market that is saturated with well-established therapies. What factors must drug developers consider when developing and launching new agents?

Scope
Overview of osteoporosis: disease description, prevalence, and economic burden. Current market for osteoporosis therapies: overview of common agents used to treat osteoporosis. Case study of Forteo: development and approval, launch and early performance, outlook, lessons to be learned.

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