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Published by: Espicom Healthcare Intelligence
Published: Oct. 3, 2006 - 180 Pages
Table of Contents
- OVERVIEW
- Orthopaedic Market overview
- Table 1 - 2005 Worldwide Orthopaedic Market by Product (Market Size US$26 billion)
- SPINAL MARKET
- Overview
- Fig.1: Global Spinal Market Shares, 2005
- Table 2: Leading Spinal Companies - 2005 Spinal Sales, US$ million
- Fig. 2: Worldwide Spinal Device Market 2006-2011 (CAGR = 16%)
- Fig. 3: Worldwide Spinal Device Market Scenarios 2011
- The Spine
- Spinal Disorders
- Herniated Disc
- Degenerative Disc Disease
- Facet Joint Arthritis
- Stenosis
- Spondylolisthesis
- Spondylolysis
- Scoliosis
- Trauma
- Tumours
- Back Pain
- Traditional Surgical Treatments
- Spinal Fusion
- Spine Surgery Instrumentation
- Bone Grafts
- Demineralised Bone Matrix
- Synthetic Substitutes
- Bone Morphogenetic Protein (BMP)
- Electrical Stimulation Units
- IntraDiscal ElectroThermal (IDET) Therapy
- Market Dynamics
- Favourable Demographics
- Development of new implants for younger patients
- Increased use of implants
- Increased use of minimally-invasive procedures
- Orthobiologics/Osteobiologics
- Gene Therapy
- Switch from fusion to motion-preserving devices
- MOTION PRESERVATION/NON-FUSION Market
- Table 3: Projected Worldwide Spinal Fusion/Motion Preservation Device Revenues 2006-2011
- Table 4: Projected Worldwide Spinal Motion Preservation Device Revenues 2006-2011
- TOTAL DISC REPLACEMENTS
- Table 5: Criteria to Determine Candidacy for TDR
- LUMBAR DISCS
- Table 6: Select Lumbar Discs - Design Comparison
- DePuy Spine - Charité Artificial Lumbar Disc
- Charité Clinical Trial Results
- Synthes
- ProDisc-L
- Charité vs ProDisc
- Medtronic Sofamor Danek.(MSD)
- Maverick Artificial Lumbar Disc
- US Clinical Trial
- Stryker Spine
- FlexiCore Artificial Lumbar Disc
- B..Braun/Aesculap
- activL
- SpinalMotion
- Kineflex Lumbar Disc
- LDR
- Mobidisc
- Vertebron
- Lumbar Motion Preservation (LMP)
- Theken Disc
- eDisc
- Ranier Technology
- CAdisc
- AxioMed
- Freedom Lumbar Disc
- TranS1
- Percutaneous Disc Reconstruction (PDR)
- NuVasive
- SpineMedica
- SaluDisc
- Biomet./.EBI
- Rescue Total Disc Replacement
- Min T Total Disc Replacement
- Amedica
- Altia Spinal Disc
- Nexgen Spine
- Physio-L
- US Spine
- Spartacus
- Zimmer
- Dynardi Artificial Lumbar Disc
- Disc Motion Technologies
- Total Spinal Motion Segment System (TSMS)
- Table 7: Lumbar Total Disc Replacement Devices - Competitive Landscape
- CERVICAL DISCS
- Medtronic Sofamor Danek
- Prestige ST Cervical Disc
- Prestige ST - US Clinical Trial Results
- Prestige LP Cervical Disc
- Prestige LP - US Clinical Trial
- Bryan Cervical Disc System
- Bryan and Prestige ST - US Clinical Trials
- Synthes
- ProDisc-C
- Cervitech
- PCM (Porous Coated Motion) Cervical Disc System
- US Clinical Trial
- LDR Spine
- Mobi-C
- SpinalMotion
- Kineflex/C Cervical Disc
- Stryker Spine
- CerviCore Artificial Cervical Disc
- Globus Medical
- Secure-C Cervical Artificial Disc
- Scient’x
- Discocerv
- NuVasive
- CerPass
- NeoDisc
- DePuy Spine
- Discover Artificial Cervical Disc
- Vertebron
- Cervical Motion Preservation Device (CMP)
- Blackstone Medical
- Advent Cervical Disc
- Table 8: Cervical Total Disc Replacement Products - Competitive Landscape
- Market Outlook.-.Total Disc Replacements
- Table 9: Projected Worldwide TDR Revenues 2006-2011
- Table 10: Projected Worldwide TDR Market, 2011
- NUCLEUS REPLACEMENT DEVICES
- Raymedica
- HydraFlex Nucleus Arthroplasty System
- PDN-Solo and PDN-Solo XL
- PDN-Solo, 24-Month Preliminary Results of International Multi-centre Study
- PDN Study - 10-Year Results with 1st Generation PDN Disc
- Spine Wave
- NuCore Injectable Nucleus
- IDE Clinical Trial
- First arm study findings
- Pioneer Surgical Technology
- Nubac Disc Arthroplasty System
- Disc Dynamics Inc
- Dascor Disc Arthroplasty System
- CryoLife
- BioDisc
- BioDisc Study
- Biomet/EBI
- Regain Lumbar Nucleus Replacement
- TranS1
- PNR
- Arthro Kinetics
- NuCell
- Zimmer
- Injectable Hyrodgel Nucleus Device
- Synthes Spine
- Hydrafil
- Replication Medical
- NeuDisc
- Gentis
- DiscCell
- Progress Update
- Table 11: Nucleus Replacement Devices - Competitive Landscape
- Market Outlook.-.Nucleus Replacement Devices
- Table 12: Projected Worldwide Partial Replacement Device Revenues 2006-2011
- DYNAMIC STABILISATION systems
- Pedicle Screw-Based Systems
- Zimmer
- Dynesys
- SpineVision (FlexSpine)
- FlexPLUS
- Applied Spine Technologies
- Stabilimax NZ
- Scient’x
- Isobar TTL
- N Spine
- N Flex
- Globus Medical
- Posterior Dynamic Stabilisation System
- Alphatec Spine
- Mekanika
- Modulus 60C
- Innovative Spinal Technologies (IST)
- Interspinous Spacer Systems
- St. Francis Medical Technologies
- X Stop Interspinous Process Decompression (IPD) System
- X Stop PK
- X Stop Clinical Trial Data
- Abbott Spine
- Wallis Stabilisation System
- US Clinical Trial
- Medtronic Sofamor Danek
- DIAM Spinal Stabilisation System
- Paradigm Spine
- coflex
- Fixano
- Interspinous U
- NuVasive
- ExtenSure
- Biomet
- Interspinous System (ISS)
- Biorthex
- Actipore Vertebral Body Replacement System
- GM Reis
- Dynafix
- Facet Joint Replacement Devices
- Archus Orthopedics
- Total Facet Arthroplasty System (TFAS)
- Facet Solutions
- Anatomic Facet Replacement System
- Impliant
- TOPS Motion Preservation System
- Spinal Elements (formerly Quantum Orthopedics)
- Zyre Facet Arthroplasty System
- Market Outlook.-.Dynamic Stabilisation Ssystems
- Table 13: Dynamic Stabilisation Systems - Competitive Landscape
- Table 14: Projected Worldwide Dynamic Stablisation Device Revenues 2006-2011
- ANNULAR REPAIR
- Anulex Technologies
- Inclose Surgical Mesh System
- Intrinsic Therapeutics
- NUCLEUS REMOVAL DEVICES
- CoreSpine Technologies
- Complete Nucleus Removal (CNR) Device
- ORTHOBIOLOGICS
- Medtronic
- InFUSE Bone Graft
- Stryker Biotech
- OP-1
- CELL THERAPY
- co-don
- co don chondrotransplant DISC
- EuroDISC Study
- STEM CELL THERAPY
- Blackstone Medical/Osiris
- Trinity Matrix/Osteocel
- Aastrom Biosciences
- Tissue Repair Cell (TRC)
- GENE-bASED DIAGNOSTIC TESTING
- Axial Biotech
- MINIMALLY-INVASIVE SPINAL SYSTEMS
- Endius
- Atavi Atraumatic Spine Surgery System
- Medtronic Sofamor Danek
- MAST
- CD Horizon Sextant Rod Insertion System
- CD Horizon Eclipse
- METRx System
- X-Tube
- Arthro Kinetics
- KISS
- Globus Medical
- Pivot MIS System
- DePuy Spine
- Pipeline, Concorde and Viper
- Aperture Spinal Access System
- Abbott Spine
- PathFinder
- TraXis
- Harmony
- NuVasive
- Zimmer
- VuePASS Portal Access Surgical System
- US Spine
- Facet Fixation System
- Mazor Surgical Technologies’
- SpineAssist
- DiscAssist
- REGIONAL MARKETS
- Fig. 4: Projected Motion Preservation Market by Region, 2006-2011
- Table 15: Projected Motion Preservation Market by Region, 2006-2011
- US
- Table 16: Back-related Diagnoses in the US in 2003
- Table 17: Spine Procedures in the US in 2003
- Europe
- Asia Pacific
- Latin America
- MOTION PRESERVATION - CONCLUSIONS
- MANUFACTURERS
- Aastrom Biosciences
- Agreements
- Orthovita
- Abbott Spine
- Acquisitions
- Spinal Concepts
- Spine Next SA
- Agreements
- Invibio
- AlloSource
- curasan
- Alphatec Spine
- Acquisitions
- Cortek
- Agreements
- IsoTis
- Hansen A Yuan
- Financials
- Amedica
- Patent Portfolio
- Metal-on-Ceramic Bearings Patent
- Spine Graft Patent
- Agreements
- Funding
- Anulex Technologies
- Annular Repair
- Funding
- Applied Spine Technologies
- Funding
- Archus Orthopedics
- Series C Financing
- Arthro Kinetics
- Joint Venture
- Australian Biotechnologies Pty Ltd
- Axial Biotech
- Funding
- AxioMed Spine
- Financials
- Biomet
- Motion Preservation Products
- Financials - Spinal Products
- US Spinal Products Market,.2005-2006
- Biorthex
- Agreements
- Nitinol Device & Components
- Blackstone Medical
- Proposed Acquisition by Orthofix International
- B..Braun/Aesculap
- Cervitech
- Funding
- co don
- CoreSpine Technologies
- Corin
- Financials
- CryoLife
- Financials
- DePuy Spine
- Acquisitions
- Bright Group’s Minimally-invasive Spinal Technology
- Link Spine Group
- Financials
- Disc Dynamics
- Funding
- Disc Motion Technologies
- Dynamic Spine
- Endius
- Facet Solutions
- Funding
- Fixano
- GM Reis
- Gentis
- Funding
- Genzyme
- Synvisc Clinical Trial Data
- Additional Study Findings
- Globus Medical
- Financials
- Impliant
- Financials
- Innovative Spinal Technologies
- Financials
- Agreements
- GE Healthcare Technologies
- Intrinsic Therapeutics
- Funding
- K2M
- Funding
- LDR
- Funding
- Life Spine
- Mazor Surgical Technologies
- Funding
- Medtronic Sofamor Danek
- Non-Fusion Acquisitions
- Spinal Dynamics Corporation
- Agreements
- Wyeth and Yamanouchi Pharmaceutical
- Financials
- Mekanika
- N Spine
- Funding
- Nexgen Spine
- NuVasive
- Acquisitions
- NeoDisc Technology
- ExtenSure
- Financials
- Orthofix
- Agreement to acquire Blackstone Medical
- Financials
- Orthonics
- Osiris Therapeutics
- Osteocel
- Financials
- Paradigm Spine
- Adolescent Idiopathic Scoliosis - Canadian Study
- Pioneer Surgical Technology
- Ranier Technology
- Funding
- Raymedica
- Funding
- Replication Medical
- Funding
- Scient’x
- Agreements
- Encore Medical
- SeaSpine
- Spinal Elements.(formerly Quantum Orthopedics)
- SpinalMotion
- Spine Wave
- Funding
- SpineVision
- SpineMedica
- Agreements
- SaluMedica
- Spinal Restoration
- St..Francis Medical Technologies
- X Stop Interspinous Process Decompression (IPD) System
- Stryker Spine
- Stryker Biotech - Orthobiologics
- Financials
- Synthes
- Acquisitions
- Gelifex
- Spine Solutions
- Minority Investments
- Innovative Spinal Technologies
- Financials
- Theken Disc
- Funding
- TranS1
- Funding
- US Spine
- Funding
- Verterbron
- Agreements
- medArtis International
- Innovasis
- US Tissue and Cell
- Musculoskeletal Transplant Foundation
- Acquisitions
- Intellectual Property
- Funding
- X-spine
- Financials
- Zimmer Spine
- Agreements
- ISTO Technologies
- Revivicor
- Tutogen Medical
- Massachusetts General Hospital and Cambridge Polymer Group
- Financials
- Table 18: Zimmer Spine Sales by Geographic Region, 2004-2005 (US$ million)
- Table 19: Zimmer’s Global Orthopaedic Market Estimates
- References
- Index of tables
- Table 1 - 2005 Worldwide Orthopaedic Market by Product (Market Size US$26 billion)
- Fig.1: Global Spinal Market Shares, 2005
- Table 2: Leading Spinal Companies - 2005 Spinal Sales, US$ million
- Table 3: Projected Worldwide Spinal Fusion/Motion Preservation Device Revenues 2006-2011
- Table 4: Projected Worldwide Spinal Motion Preservation Device Revenues 2006-2011
- Table 5: Criteria to Determine Candidacy for TDR
- Table 6: Select Lumbar Discs - Design Comparison
- Table 7: Lumbar Total Disc Replacement Devices - Competitive Landscape
- Table 8: Cervical Total Disc Replacement Products - Competitive Landscape
- Table 9: Projected Worldwide TDR Revenues 2006-2011
- Table 10: Projected Worldwide TDR Market, 2011
- Table 11: Nucleus Replacement Devices - Competitive Landscape
- Table 12: Projected Worldwide Partial Replacement Device Revenues 2006-2011
- Table 13: Dynamic Stabilisation Systems - Competitive Landscape
- Table 14: Projected Worldwide Dynamic Stablisation Device Revenues 2006-2011
- Table 15: Projected Motion Preservation Market by Region, 2006-2011
- Table 16: Back-related Diagnoses in the US in 2003
- Table 17: Spine Procedures in the US in 2003
- Table 18: Zimmer Spine Sales by Geographic Region, 2004-2005 (US$ million)
- Table 19: Zimmer’s Global Orthopaedic Market Estimates
Abstract"By 2011, motion preservation technologies will achieve revenues of US$5.1 billion and account for 50% of the market"
Motion preservation is the hottest topic around in spinal orthopaedics - a sector forecast to achieve 16% growth per year till 2011.
The concept of motion preservation in the spine is an intriguing one and the array of non-fusion technologies being introduced to the market offer a great deal of promise for spinal surgery patients.
However, despite the fact that some of these technologies have been in use in Europe and other international markets for many years, the clinical outcomes data available are extremely limited in proportion to the tens of thousands of procedures performed. While this has apparently not inhibited international growth, regulatory clearance criteria in the US are by far the most rigorous in the world. As such, the paucity of well-designed studies to prove the safety and effectiveness of artificial discs may hinder growth in the US.
Despite the lack of evidence, patient demand has not been dampened. A recent industry study of 461 prospective spine fusion patients, found that 49% would rather wait for a motion preserving implant than undergo a fusion procedure. A further 26% are still weighing the pros and cons of the two surgeries. Only 26% opted for the fusion procedure. Of course, owing to the many contradictions for total disc replacement, not all patients will be suitable candidates for the procedure.
What has become clear is that for optimal results, patient selection is critical with poor selection too often resulting in poor outcome. For certain segments of the patient population, traditional fusion will remain the appropriate therapy.
What’s it all about?
Spinal fusion has become the standard surgical care for numerous pathologic conditions of the spine. Spinal fusion surgery is frequently performed to treat spinal disorders such as spondylolisthesis, scoliosis, degenerative disc disease (DDD), instability of the spine or spinal fractures.
An alternative to spinal fusion in the treatment of DDD, is an artificial intervertebral disc. Unlike spinal fusion which achieves pain relief through immobilisation, artificial discs maintain motion at the operative level once the damaged disc has been removed. By preserving normal physiological motion, it is thought this may also reduce or prevent the development of adjacent segment degeneration. In addition, a bone graft is not required for an artificial disc replacement and this alleviates complications such as bone graft donor site pain and pseudo-arthritis. Furthermore, artificial disc replacements provide a more rapid return to activity than fusion surgery which requires time for the bone graft to grow into a solid mass.
This report provides real insights:
For executives working in industry and commerce, the need to understand the issues, players and products in this sector of high growth potential is essential. That is why Espicom, for 25 years a leading publisher of strategic business information for the medical device community, has published this extensive report.
In over 175-pages, the report examines the background to market, provides key figures and estimates for market growth and examines in-depth the companies and innovative products that are driving change.
This report answers key business questions:
- What % of the market may be taken by the fledgling disc nucleus replacement market if it can overcome regulatory obstacles in the USA?
- What competitive impact will Medtronic’s breakthrough have in the US cervical TDR market?
- What % of the global market will Dynamic Stabilisation Systems command in 2011?
- What is the potential for minimally-invasive spinal technology?
- Which development companies have the most promising and innovative technology and present the most attractive acquisition targets?
- To what degree will gene-based diagnostic testing affect the market in the future?
Providing:
- Comprehensive market forecasts of technology and application sectors to 2011
- A thorough review of the spinal orthopaedic market worldwide
An examination of key products that are currently in development:
- Total Disc Replacement
- Dynamic Stabilisation Devices
- Disc Nucleus Replacement
A competitive review of 63 companies actively developing spinal preservation products
Get Full Details About This Report >>
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