Biosensors in Medical Diagnostics

Published by: Global Industry Analysts

Published: Aug. 1, 2006 - 207 Pages

Table of Contents

I-A. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability And Reporting Limitations

Disclaimers

Data Interpretation & Reporting Level

Quantitative Techniques & Analytics

Product Definitions And Scope Of Study

Medical Biosensors

Glucose Sensors

Other Sensors

Environmental Biosensors

Other Biosensors

I-B. GENERAL OVERVIEW OF MEDICAL DEVICES AND DIAGNOSTICS INDUSTRY

II. EXECUTIVE SUMMARY

1. Global Market Overview and Analysis

Commercialization of Biosensors-Challenges Ahead

Facts and General Trends

Impediments to Commercialization

Global Biosensors Market

Medical Biosensors: A Promising Area

Increasing Medical Applications for Biosensors

Painless Technologies Spark Evolution in Glucose Monitoring Segment

Biosensors Primarily Used in Blood Gas/Electrolyte Analyzers, Glucose Meters & Metabolite Analyzers

2. A Retrospective

3. Competitive Scenario

Intensity of Competition

4. Product Overview

About Biosensors

Types of Biosensors

Components of Biosensors

Types of Biosensors

Glucose Sensor

Medical Telesensors

Detecting Cancer and Health Abnormalities

Lactate Sensor

Alcohol Sensor

Biochemical Oxygen Demand Sensor (BOD)

Bioreporters

Miniaturized Devices

Components of Biosensors

Components Include

Receptor

Transducer

Separator

Biological Components

Attributes of a Good Biosensor

Classes of Biosensors

Potentiometric

Amperometric

Optical Biosensors

Other Physicochemical Biosensors

Methods to Manufacture Optical Biosensors

Simple Fiber Optic Biosensors

Evanescent Wave System

Surface Plasmon Resonance (SPR)

5. Application Areas

A. Medical Applications

Glucose Meters

The Diabetes Monitoring Market

Categorization

Biosensors in Home Glucose Monitors

PBGM Devices: Based on Photometric or Biosensor Technology

Product Innovations Rule the Roost

Non-Invasive Products

The Blood Gas Market

Sensors Facilitate Analysis of Blood

Market for DNA Biosensors and Genechips in Nascent Stage

B. Environmental Biosensors

C. Industrial Applications

Summarization of Available Biosensors & Technological Applications

D. Other Application Areas

Biological Warfare- An Increasingly Important Area for Biosensors

Fingerprinting- A Much Needed Advantage?

6. Recent Industry Activity

EPSRC Enters Joint Research Agreement with Philips

Biophage Pharma Enters Agreement with Biosensor Systems

Kimberly-Clark Acquires Stake in Axela Biosensors

Axis Participates in Biosensor Platform Development Project

US Genomics Bags Biosensor Contract from DHS

Bio-Nano Sensium Files Patent Application for Wireless Biosensors

SPO Medical Completes Reverse Acquisition of United Diagnostic

Biophage Pharma Develops New Technology to Detect Bacteria

Cygnus Turns to Liquidation

TGC Research Acquires Certain Assets of Diametrics

Diametrics Restructures

Abbott Acquires I-Stat

Seahawk Contracts with In-Q-Tel

Pinnacle Signs an Agreement with Primetech

RoboDesign Enters into an Agreement with Isis

Theron Enters into a Licensing Agreement

Innovative Biosensors Enters Licensing Agreement with MIT

Biosensors International and X-Cell Medical Mutually Agree to Form a New Company

Biosensors International Private Ltd. Divests Stent System to Guidant Corporation

Medtronic Acquires MiniMed, Inc. and Medical Research Group, Inc.

Virtek Vision Acquires FONA Diagnostics

Dow Corning Strategically Alliances with Genencor

Synthetic Blood International Obtains Patent

Prolinx Forges an Agreement with Texas Instruments

Kumetrix Bags SBIR Contract from NIDDK

Standard MEMS Forms BioMEMS Technology Group

7. Technological Developments

Holograms - The Next Generation Biosensors ..

Smart Bandages- A New Way of Wound Care

Axela Biosensors to Launch dotLab™ System

PulseTracer Unveils PT100 Biosensor

Molecular Biology- Increasingly Used in the Biosensor Business

Micro-System Platforms for Biosensor Applications

Microelectromechanical Systems- Creating New Horizons

Biochips: Increasingly Being Used in Point-Of-Care Devices

Implantable Biosensors: A Possibility in the Near Future

Biosensors to Carry Out Medical-Checkups at Home

Immunosensors to Enhance Current Immunoassay Techniques

Microfluidic Glucose Sensor

Biosensors in Mycotoxin Detection

Some Major Technological Developments in Recent Years

Animas into Development of Implantable Sensors for Blood Glucose

Cytoplex Develops Biosensor

Immunosensor Ricin Detector

Biosensor to Identify Viruses Electronically

Electrochemical Array Biosensor Technology

Polymer-Coated Microheaters Enters Market

Animas into Development of Implantable Sensors for Blood Glucose

Technology Archive

UCSD Instrumental in the Development of Polymer-based, Nanoscale Biosensors

Applied Digital Solutions Launches VeriChip™

Applied Digital Solutions, Inc. Incorporates Biosensors Technology in New Device

University of Rhode Island Develops Biosensor to Detect Pathological Bacteria in Foods

Cellomics Launches the Development of Biowarfare Detection

Biosensors- Speed Pathogen Detection

Optic Interferometic Sensor for Detecting Biological Hazards and Attacks

Digital Signal Processing Technology (DSP) in Biosensors

The World’s Smallest Biosensors

MiniMed Gains FDA Approval for Its Subcutaneous Glucose Sensor

The Nanomachine: The World’s Smallest Machine

Knoxville Cancer Survival Center Develops Laser-based Sensor

Genetic Engineering Creates Biosensors to Clean Environment

New Horizons Develops Immunoassay Tests

John Hopkins University Develops New Alfa-Toxin Fab

Texas Instruments Develops a New Surface Plasmon Resonance Sensor

A New Biosensor to Confirm Pregnancy

Gold Biosensor to Detect Carcinogens

Drug Detecting Biosensor

Functional Genomics Technology Uses Biosensors

8. Focus on Select Players

Companies Developing Biosensor-Based Devices

Abbott laboratories

I-Stat Corporation (USA)

Affinity Sensors (USA)

IAsys Plus

Bayer Diagnostics (USA)

Animas Corp (US)

Lifescan, Inc. (USA)

Medtronic MiniMed Inc. (USA)

Roche Diagnostics (USA)

Leading Developers of Biosensor Technology

AgaMatrix Inc. (USA)

Cranfield Biotechnology Center (UK)

LifeSensors INC. (USA)

M-Biotech (USA)

Nova Biomedical (USA)

9. Global Market Perspective

Table 1: World Recent Past, Current & Future Market Analysis for Biosensors by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 2: World 10-Year Perspective for Biosensors by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 3: World Recent Past, Current & Future Market Analysis for Medical Biosensors by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 4: World Recent Past, Current & Future Market Analysis for Medical Biosensors by Product Segments- Glucose Biosensors and Other Medical Biosensors Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010) (includes corresponding Graph/Chart)

Table 5: World 10-Year Perspective for Medical Biosensors by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 6: World 10-Year Perspective for Medical Biosensors by Product Segment- Percentage Breakdown of Dollar Sales for Glucose Biosensors and Other Medical Biosensors Markets for Years 2000, 2005 & 2010

Table 7: World Recent Past, Current & Future Market Analysis for Glucose Biosensors by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 8: World 10-Year Perspective for Glucose Biosensor by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 9: World Recent Past, Current & Future Market Analysis for Other Medical Biosensors by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 10: World 10-Year Perspective for Other Medical Biosensor by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 11: World Recent Past, Current & Future Market Analysis for Environmental Biosensors by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 12: World 10-Year Perspective for Environmental Biosensor by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Markets for Years 2000, 2005 & 2010. (includes corresponding Graph/Chart)

Table 13: World Recent Past, Current & Future Market Analysis for Other Biosensors by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 14: World 10-Year Perspective for Other Biosensor by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

III. MARKET

1. The United States

A.Market Analysis

Other Facts and Figures

The US Diabetes Monitoring Market

Biosensors- Speeding Pathogen Detection

Product Launches/Innovations

Strategic Corporate Developments

Focus on Select Key Players

Companies Developing Biosensor-Based Devices

Abbott Laboratories

I-Stat Corporation

Affinity Sensors

IAsys Plus

Animas Corporation

Bayer Diagnostics

LifeScan

Medtronic MiniMed Inc

Roche Diagnostics

Leading Developers of Biosensor Technology

AgaMatrix Inc.

LifeSensors Inc.

M-Biotech

Nova Biomedical

B.Market Estimates/Projections

Table15: US Recent Past, Current & Future Market Analysis for Biosensors by Product Segment - Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table16: US 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/Chart)

2. Canada

A.Market Analysis

Biosensor Researches in Canada

Microfluidic Systems

Biosensor Institutions

Product Launch

B.Market Estimates/Projections

Table17: Canadian Recent Past, Current & Future Market Analysis for Biosensors by Product Segment - Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 18: Canadian 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/ Chart)

3. Japan

A.Market Analysis

Strategic Corporate Developments

B.Market Estimates/Projections

Table 19: Japanese Recent Past, Current & Future Market Analysis for Biosensors by Product Segment - Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 20: Japanese 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/ Chart)

4. Europe

A.Market Analysis

Market Trends & Issues

Environmental Monitoring Diffusing in the Europe Countries

B.Market Estimates/Projections

Table 21: European Recent Past, Current & Future Market Analysis for Biosensors by Geographic Region - France, Germany, Italy, UK & Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 22: European Recent Past, Current & Future Market Analysis for Biosensors by Product Segment - Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 23: European 10-Year Perspective for Biosensors by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK & Rest of Europe Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 24: European 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/ Chart)

Table25: European Recent Past, Current & Future Market Analysis for Medical Biosensors by Geographic Region - France, Germany, Italy, UK and Rest of Europe Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table26: European Recent Past, Current & Future Market Analysis for Medical Biosensors by Product Segments- Glucose Biosensors and Other Medical Biosensors Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 27: European 10-Year Perspective for Medical Biosensors by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 28: European 10-Year Perspective for Medical Biosensors by Product Segment- Percentage Breakdown of Dollar Sales for Glucose Biosensors and Other Medical Biosensors Markets for Years 2000, 2005 & 2010

Table 29: European Recent Past, Current & Future Market Analysis for Glucose Biosensors by Geographic Region -France, Germany, Italy, UK and Rest of Europe Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 30: European 10-Year Perspective for Glucose Biosensor by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 31: European Recent Past, Current & Future Market Analysis for Other Medical Biosensors by Geographic Region - France, Germany, Italy, UK and Rest of Europe Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 32: European 10-Year Perspective for Other Medical Biosensor by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 33: European Recent Past, Current & Future Market Analysis for Environmental Biosensors by Geographic Region - France, Germany, Italy, UK and Rest of Europe Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 34: European 10-Year Perspective for Environmental Biosensor by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

Table 35: European Recent Past, Current & Future Market Analysis for Other Biosensors by Geographic Region - France, Germany, Italy, UK and Rest of Europe Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 36: European 10-Year Perspective for Other Biosensor by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart)

4a. France

A.Market Analysis

B.Market Estimates/Projections

Table 37: French Recent Past, Current & Future Market Analysis for Biosensors by Product Segment - Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table38: French 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/Chart)

4b. Germany

A.Market Analysis

B.Market Estimates/Projections

Table 39: German Recent Past, Current & Future Market Analysis for Biosensors by Product Segment - Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 40: German 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/ Chart)

4c. Italy

A.Market Analysis

B.Market Estimates/Projections

Table 41: Italian Recent Past, Current & Future Market Analysis for Biosensors by Product Segment - Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 42: Italian 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/ Chart)

4d. The United Kingdom

A.Market Analysis

Future Outlook of Industrial Biosensors

Leading Developers of Biosensor Technology in UK

Cranfield Biotechnology Center

Strategic Corporate Developments

B.Market Estimates/Projections

Table 43: UK Recent Past, Current & Future Market Analysis for Biosensors by Product Segment - Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 44: UK 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/Chart)

4e. Rest of Europe

A.Market Analysis

Strategic Corporate Developments

B.Market Estimates/Projections

Table 45: Rest of Europe Market for Biosensors - Recent Past, Current & Future Analysis by Product Segment for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 46: Rest of Europe 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/ Chart)

5. Asia-Pacific

A.Market Analysis

Historic Review

CFTRI of India Announces New Biosensor

CRC Develops an Extremely High Sensor

Nanomachine Developed in Australia

B.Market Estimates/Projections

Table 47: Asia Pacific Market for Biosensors - Recent Past, Current & Future Analysis by Product Segment for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 48: Asia Pacific 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/ Chart)

6. Rest of World

A.Market Analysis

B.Market Estimates/Projections

Table 49:Rest of World Market for Biosensors - Recent Past, Current & Future Analysis by Product Segment for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 50: Rest of World 10-Year Perspective for Biosensors by Product Segment - Percentage Breakdown of Dollar Sales for Medical Biosensors (Glucose Biosensors and Other Medical Biosensors), Environmental Biosensors and Other Biosensors Markets for 2000, 2005 & 2010 (includes corresponding Graph/ Chart)

IV. COMPETITION

1. Abbott Laboratories (USA)

Table 51: Annual Sales Analysis: 2003-2005 (In US$ Billion)

Table 52: Annual Sales Analysis by Quarter: 2004-2005 (In US$ billion)

Table 53: Annual Sales Analysis by Segment: 2004-2005 (In US$ billion)

Table 54: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ billion)

Abbott Point Of Care (USA)

2. Abtech Scientific, Inc. (USA)

3. Agamatrix, Inc. (USA)

4. Applied Biophysics, Inc. (USA)

5. Axela Biosensors, Inc. (Canada)

6. Axis-Shield PLC (UK)

Table 55: Annual Sales Analysis: 2003-2005 (In £ million)

Table 56: Annual Sales Analysis by Segment: 2004-2005 (In £ million)

7. Biacore International AB (Sweden)

8. Bio-Nano Sensium Technologies (UK)

9. Biophage Pharma, Inc. (Canada)

Table 57: Nine Months Sales Analysis: 2005-2004 (Nine Months Ended, August) (In Can$ million)

Table 58: Nine Months Sales Analysis by Quarter: 2005- 2004 (Nine Months Ended, August) (In Can$ million)

10. Biosensor Applications Sweden AB (Sweden)

Table 59: Annual Sales Analysis: 2003-2005 (In SEK million)

11. Biosensor Systems Design, Inc. (USA)

12. BST Bio Sensor Technologie GmbH (Germany)

13. Cranfield Biotechnology Center (UK)

14. Cytoplex Biosciences (USA)

15. Digital Angel Corporation (USA)

16. Engineering And Physical Sciences Research Council (United Kingdom)

17. Epocal, Inc. (Canada)

18. Farfield Group Ltd. (UK)

Neosensors Limited (UK)

19. Gambro AB (Sweden)

20. Genencor International, Inc. (USA)

21. IMEC (Belgium)

22. Lifescan, Inc. (USA)

Animas Corporation (USA)

23. LifeSensors, Inc. (USA)

24. Maxtec, Inc. (USA)

25. M-Biotech, Inc. (USA)

26. Medtronic MiniMed, Inc. (USA)

27. Nanosensors, Inc. (USA)

28. Neurometrix, Inc. (USA)

29. Nova Biomedical (USA)

30. Oak Ridge National Laboratory (USA)

31. Oxford Biosensors Ltd. (UK)

32. Pelikan Technologies, Inc. (USA)

33. Philips Research (The Netherlands)

34. Pinnacle Technology, Inc. (USA)

35. Primetech Corporation (Japan)

36. Pulsetracer Technologies, Inc. (Canada)

37. Remedios Ltd. (UK)

38. Roche Diagnostics Corporation (USA)

39. Sensalyse Ltd. (UK)

40. Senslab GmbH (Germany)

41. Siemens Medical Solutions (Germany)

42. Siemens Medical Solutions USA, Inc. (USA)

43. SPO Medical, Inc. (USA)

Table 60: First Quarter Sales Analysis: 2005-2006 (Q1) (In US$ million)

Table 61: Annual Sales Analysis: 2004-2005 (In US$ million)

44. Synthetic Blood International, Inc. (USA)

45. Universal Sensors, Inc. (USA)

46. U.S. Genomics, Inc. (USA)

47. Virtek Vision International, Inc. (Canada)

48. YSI, Inc. (USA)

Abstract

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