Industrial Enzymes

Published by: Global Industry Analysts

Published: Aug. 1, 2006 - 368 Pages

Table of Contents

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations

Disclaimers

Data Interpretation & Reporting Level

Quantitative Techniques & Analytics

Product Definitions And Scope of Study

Product Segments

End-Use Segments

Definitions:

Industrial Enzymes

Industrial Carbohydrases

Industrial Proteases

Industrial Lipases

Others include Amylase, Cellulase, Hemicellulase, Isomerase, Lactases, and Oxidases

II. EXECUTIVE SUMMARY

1. Outlook

Market Snapshots

Technological Developments Set to Drive Growth for Industrial Enzymes

Competitive Scenario

Market Leaders

Table 1: Leading Players in the Global Industrial Enzymes Market (2005 & 2006): Percentage Breakdown of Value Sales for Novozymes, Danisco, DSM, and Others (includes corresponding Graph/Chart)

Pricing: The King Maker

Competitor Analysis

2. Industry Overview

Characteristics of the Market

Production and Consumption Pattern

Imports Expensive

Steady Growth

Ailed by Buyer’s Purchasing Power

Industry Drivers

Market Restraints

High Costs Stray Research

Market Maturity

Utility of New Technologies Tainted by Consumer Attitudes

Regulations Limit Market Potential

Strangled by Low Prices

Captive Production Capsizes Industry fortunes

Regulations

Emerging Trends

Surging Demand for Eco-Friendly Enzymes Spurs R&D Activities

Rapid Growth in Feed Enzyme Technology

Niche Marketing to Tide Over Commoditization

Economic Viability Upstages

Demand Acceleration for Enzymes in Diverse Industries

Need for Environmentally Friendly Processes Fuel Enzymes Sales

Diversifying Interests

Partnerships Spark Growth

Current and Future Analysis

Historic Review

3. Focus on Key Regional Markets

United States: Zooming Ahead at 5%

Europe: The Largest Market for Industrial Enzymes Worldwide

Asia-Pacific: Bountiful Opportunities

4. Select Segmental Analysis

Product Segments

Carbohydrases

Proteases

Lipases

End Use Segments

Food & Feed

Detergents

Innovative Enzymes Spice up the Detergents Market

Pulp & Paper

5. Product Overview

Enzymes - An Introduction

Role in Digestion and Metabolism

Effects of Enzyme Deficiency in Human Body

Advantages of Enzymes Vis-à-vis Chemical Catalysts

Historical Perspective

Market-Based Classification of Enzymes

Industrial Enzymes

The Quest for the Best

Limited Reproducibility in Hosts Starves Commercial Applications

Thermal Instability - A Process Stalemate

Denaturing of Enzymes Hampers Reuse

Low Catalytic Activity in Process Conditions - Technical Impasse

Enzymes Trigger Allergies - Voicing Serious Concerns

Industry Specific Challenges to Industrial Enzymes

The First Industrial Enzymes

Production Methods

Extraction from Plants or Animal Tissue

Culture of Microbial Hosts

Role of Biotechnology and Recombinant DNA Technologies

Extremophiles - A New Found Bliss for the Industry

Applications of Extremozymes Derived from Extremophiles

Transgenic Plants Emerge as Valuable Sources of Enzymes

Applications of Enzymes in Various End-Use Industries

Classification and Nomenclature of Industrial Enzymes

Industrial Carbohydrases

Amylases

Cellulases

Dextranase and Dextrinase

Glucose Isomerase

Galactosidase

Invertase

Naringinase

Pectinase

Pullulanase

Xylanase

Glucose Oxidase

Industrial Proteases

Alkaline Proteases

Chymosin

Lactase

Rennin

Papain

Bromelain

Keratinases

Application Areas of Industrial Proteases

Industrial Lipases

Other Industrial Enzymes

Amidases

Laccase

Lyases

Oxireductases

Phytase

Transferases

What’s In for Future?

6. End-Use Analysis

Food & Feed

Food Enzymes

Starch Processing

Brewing

Clear Beer

Beer for Calorie Conscious Consumers

Dairy

Cheese Making

Enhancement of Cheese Flavor

Baking

Replacement of Bromide

Replacement of Bromate

Enzymes for Softer Breads

Fruit Juice

Crystal Clear Juice

Feed Enzymes

Enzymes Enhance Nutrient Metabolism

Detergents

Enzyme Based Detergent Vs Conventional Synthetic Detergent

Removal of Stains

Grease Removal

Textiles

De-Starching Agents

Stonewashing Denim

Yarn Bleaching

Pulp and Paper

Pulping

Deinking

Leather

Processing of Leather

Dehairing

Bating

Degreasing

Other Enzymatic Uses

Enzymes for Meat tenderness

Enzymes Increase Confections’ Shelf Life

Cleans Contact Lens

Enzymes in Cosmetic Applications

Energy

Enzymes in Ethanol Production

7. Industrial Enzymes and the Environment

Enzymes Reduce Environmental Impact

Safer Workplace

Energy Conservation

Emerging Applications

Wastewater Treatment

8. Technological Development

Novozymes Develops Low-cost Lipozyme TL IM

Danisco-Genencor Develops New Enzyme

Textan Chemicals Develops Xylanase

Researchers of INEEL Discover a New Enzyme for Wastewater Treatment

Researchers of PNNL Find Technique to Immobilize Enzymes on Silica

Hayashibara Discovers a New Method to Manufacture Cyclic Tetrasaccharide

MIT Discovers Technique to Trace Active Industrial Enzymes

Protein Engineering Technology - A Key Historic Technology Break Through

Utility of Protein Engineering in Changing Enzyme Attributes

9. Product Introductions/Innovations

DSM Launches Rapidase Intense

Novozymes Launches Liquanase

DSM Launches Accelerzyme CPG

Danisco Launches New Pectolytic Enzymes

New Sanitizing Enzyme from Genencor

Ultra-Thin Approved by USFDA

European Commission Approves Danisco’s Avizyme® 1500

Danisco Launches New Enzymes for Baking Industry

AB Enzymes Launches Veron Brox in Asia

Genencor Launches New Enzymes

Novozymes and Chr. Hansen Jointly Launch YieldMax

Novozymes Launches New Industrial Enzymes

Danisco Cultor Unveils The Powerbake (Grindamyl) Line

10. Recent Industry Activity

Enzyme Majors Reach Settlement on Patent Litigations

Genencor to Participate in French Research Project

Novozymes Supplies Enzymes to Biogasol

Cornell University gets Federal Aid for Biopower Research

Dyadic Announces Genome Sequencing of C1 Fungus

Danisco Restructures R&D Facilities

Danisco Acquires Genencor

Diversa Enters into Agreement with Cargill

Genencor Plans to Establish New Plant in China

Pepscan and ServiceXS Sign Research-based Pact with Solvay Pharma

Novozymes and Chr Hansen Enter into Collaboration

Novozymes Enters into Research Collaboration with Solvay

Genencor Receives Exclusive Manufacturing and Marketing License

Danisco Wins Award for Grindamyl

Novozymes Purchases Operations of Roots

Prokaria Enters into Collaborative Agreement with Roquette

Prokaria Strikes Deal with Novozymes

Danisco Increases its Pectin Production Capacity in Czech Republic

Novozymes Buys George A. Jeffreys

AB Enzymes Acquires Gamma Chemie

Genencor Purchases Enzyme Bio-Systems

Novozymes Buys BioGaia Fermentation Plant

Novozymes and Chr. Hansen Form Alliance

Diversa Enters into a Partnership with DuPont Bio- Based Materials

Diversa Signs Agreement with Givaudan

Diversa Inks Agreement with Degussa

Novozymes Purchases Sybron Biochemicals from Bayer

Novozymes Enters into Collaboration with Maxygen

Innovase Ties-up with P&G

Genencor Inks an Agreement with Procter & Gamble

Dow Ventures with Diversa

Novo Nordisk and Roche Enter into a Global Alliance

Proteus Enters into a Licensing Agreement with University of Bern

Energy BioSystems Inks Pact with Genencor

Biotech International Inks MoU with Advanced Biochemicals

Novo Nordisk Spins-Off Enzymes Unit

11. Focus on Select Global Players

AB Enzymes Gmbh (Germany)

Advanced Enzyme Technologies Ltd. (India)

Aureozyme Inc. (USA)

Biocon Limited (India)

BioResource International (BRI) (USA)

Chr. Hansen (Denmark)

Danisco A/S (Denmark)

Genencor International, Inc. (USA) (Subsidiary of Danisco A/S)

DIREVO Biotech AG (Germany)

Diversa Corporation (USA)

DSM (The Netherlands)

Enchira Biotechnology Corporation (USA)

Enzymatic Deinking Technologies LLC (USA)

KBI BioPharma, Inc. (USA)

Maxygen (USA)

NEXGEN Biotechnologies, Inc. (Korea)

Novozymes A/S (Denmark)

12. Global Market Perspective

Table 2: World Recent Past, Current & Future Analysis for Industrial Enzymes by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 3: World Historic Review for Industrial Enzymes by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 4: World 20-Year Perspective for Industrial Enzymes by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 5: World Recent Past, Current & Future Analysis for Carbohydrases by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with nnual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 6: World Historic Review for Carbohydrases by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 7: World 20-Year Perspective for Carbohydrases by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 8: World Recent Past, Current & Future Analysis for Proteases by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 9: World Historic Review for Proteases by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 10: World 20-Year Perspective for Proteases by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 11: World Recent Past, Current & Future Analysis for Lipases by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 12: World Historic Review for Lipases by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 13: World 20-Year Perspective for Lipases by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 14: World Recent Past, Current & Future Analysis for Other Industrial Enzymes by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 15: World Historic Review for Other Industrial Enzymes by Geographic Region - USA, Canada, Japan, Europe, Asia- Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 16: World 20-Year Perspective for Other Industrial Enzymes by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia- Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 17: World Recent Past, Current & Future Analysis for Industrial Enzymes (Food & Feed) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 18: World Historic Review for Industrial Enzymes (Food & Feed) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 19: World 20-Year Perspective for Industrial Enzymes (Food & Feed) by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/ Chart)

Table 20: World Recent Past, Current & Future Analysis for Industrial Enzymes (Detergents) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 21: World Historic Review for Industrial Enzymes (Detergents) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 22: World 20-Year Perspective for Industrial Enzymes (Detergents) by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/ Chart)

Table 23: World Recent Past, Current & Future Analysis for Industrial Enzymes (Textiles) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 24: World Historic Review for Industrial Enzymes (Textiles) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 25: World 20-Year Perspective for Industrial Enzymes (Textiles) by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/ Chart)

Table 26: World Recent Past, Current & Future Analysis for Industrial Enzymes (Leather) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 27: World Historic Review for Industrial Enzymes (Leather) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 28: World 20-Year Perspective for Industrial Enzymes (Leather) by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia- Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/ Chart)

Table 29: World Recent Past, Current & Future Analysis for Industrial Enzymes (Pulp & Paper) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 30: World Historic Review for Industrial Enzymes (Pulp & Paper) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 31: World 20-Year Perspective for Industrial Enzymes (Pulp & Paper) by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/ Chart)

Table 32: World Recent Past, Current & Future Analysis for Industrial Enzymes (Other End Uses) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 33: World Historic Review for Industrial Enzymes (Other End Uses) by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 34: World 20-Year Perspective for Industrial Enzymes (Other End Uses) by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East and Latin America Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/ Chart)

III. MARKET

1. The United States

A.Market Analysis

Current & Future Analysis

Historic Review

Food Enzyme Industry: Key Challenges

Market Trends

Walking the Fine Line

Banking Upon Core Competencies

Genetically Modified Organisms (GMOs): Caught in the Swamp of Concerns

Product Approval

Strategic Corporate Developments

Key Players

Aureozyme, Inc.

BioResource International (BRI)

Diversa Corporation

Enchira Biotechnology Corporation

Enzymatic Deinking Technologies LLC

Genencor International, Inc.

KBI BioPharma, Inc.

Maxygen

B.Market Analytics

Table 35: US Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 36: US Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 37: US Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 38: US Historic Review for Industrial Enzymes by End- Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 ( includes corresponding Graph/Chart)

Table 39: US 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 40: US 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

2. Canada

Market Analysis

Current & Future Analysis

Historic Review

Table 41: Canadian Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 42: Canadian Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 43: Canadian Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 44: Canadian Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 45: Canadian 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/ Chart)

Table 46: Canadian 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

3. Japan

A.Market Analysis

Current & Future Analysis

Historic Review

Technological Development

B.Market Analytics

Table 47: Japanese Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 48: Japanese Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 49: Japanese Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 50: Japanese Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 51: Japanese 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 52: Japanese 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

4. Europe

A.Market Analysis

Current & Future Analysis

Historic Review

Market Overview

Pricing Pressures

Market Leaders

Emerging Trends

Rising Concerns for Food Safety Buoy Sales of Feed Enzymes

Genetic Engineering Upstages Viability

Dampened by Stringent Legislation

B.Market Analytics

Table 53: European Recent Past, Current & Future Analysis for Industrial Enzymes by Geographic Region - France, Germany, UK, Italy, Spain, Russia, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 54: European Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 55: European Recent Past, Current & Future Analysis for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 56: European Historic Review for Industrial Enzymes by Geographic Region - France, Germany, UK, Italy, Spain, Russia, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 57: European Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 58: European Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 59: European 20-Year Perspective for Industrial Enzymes by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, UK, Italy, Spain, Russia, and Rest of Europe Markets for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 60: European 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph /Chart)

Table 61: European 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

4a. France

A.Market Analysis

Current & Future Analysis

Historic Review

Strategic Corporate Developments

B.Market Analytics

Table 62: French Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 63: French Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 64: French Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 65: French Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 66: French 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 67: French 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

4b. Germany

A.Market Analysis

Current & Future Analysis

Historic Review

Strategic Corporate Development

Key Players

AB Enzymes GmbH

DIREVO Biotech AG

B.Market Analytics

Table 68: German Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 69: German Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 70: German Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 71: German Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 72: German 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 73: German 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

4c. The United Kingdom

Market Analysis

Current & Future Analysis

Historic Review

Table 74: UK Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 75: UK Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 76: UK Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 77: UK Historic Review for Industrial Enzymes by End- Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 78: UK 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 79: UK 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

4d. Italy

Market Analysis

Current & Future Analysis

Historic Review

Table 80: Italian Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 81: Italian Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 82: Italian Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 83: Italian Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 84: Italian 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 85: Italian 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

4e. Spain

Market Analysis

Current & Future Analysis

Historic Review

Table 86: Spanish Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 87: Spanish Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 88: Spanish Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 89: Spanish Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 90: Spanish 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 91: Spanish 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

4f. Russia

Market Analysis

Current and Future Analysis

Historic Review

Table 92: Russian Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 93: Russian Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 94: Russian Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 95: Russian Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 96: Russian 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 97: Russian 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

4g. Rest of Europe

A.Market Analysis

Current and Future Analysis

Historic Review

Product Launches/Developments

Strategic Corporate Developments

Key Players

Chr. Hansen (Denmark)

Danisco (Denmark)

DSM (Netherlands)

Novozymes A/S (Denmark)

B.Market Analytics

Table 98: Rest of Europe Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 99: Rest of Europe Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 100: Rest of Europe Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 101: Rest of Europe Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 102: Rest of Europe 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph /Chart)

Table 103: Rest of Europe 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

5. Asia-Pacific

A.Market Analysis

Current and Future Analysis

Historic Review

India - An Emerging Player

Major Players

Table104: Leading Players in the Global Industrial Enzymes Market (2005 & 2006): Percentage Breakdown of Value sales for Biocon, Novozymes, Advanced Enzyme, Rossari Biotech, Maps (India) Ltd., and Others

Product Launch

Strategic Corporate Development

Key Players

Advanced Enzyme Technologies Ltd. (India)

Biocon Limited (India)

NEXGEN Biotechnologies, Inc. (Korea)

B.Market Analytics

Table 105: Asia-Pacific Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 106: Asia-Pacific Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 107: Asia-Pacific Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 108: Asia-Pacific Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 109: Asia-Pacific 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 110: Asia-Pacific 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

6. The Middle East

Market Analysis

Current and Future Analysis

Historic Review

Table 111: Middle East Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 112: Middle East Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 113: Middle East Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million forYears 1991 through 2000 (includes corresponding Graph/Chart)

Table 114: Middle East Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 115: Middle East 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/ Chart)

Table 116: Middle East 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

7. Latin America

Market Analysis

Current and Future Analysis

Historic Review

Table 117: Latin America Recent Past, Current & Future Analysis for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/ Chart)

Table 118: Latin America Recent Past, Current & Future Analysis for Industrial Enzymes by End- Use Segments - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 2001 through 2010 (includes corresponding Graph/Chart)

Table 119: Latin America Historic Review for Industrial Enzymes by Product Segment - Carbohydrases, Proteases, Lipases, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 120: Latin America Historic Review for Industrial Enzymes by End-Use Segment - Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others Independently Analyzed with Annual Sales Figures in US$ Million for Years 1991 through 2000 (includes corresponding Graph/Chart)

Table 121: Latin America 20-Year Perspective for Industrial Enzymes by Product Segment - Percentage Breakdown of Dollar Sales for Carbohydrases, Proteases, Lipases, and Others for Years 1991, 1995, 2005 & 2010 (includes corresponding Graph/Chart)

Table 122: Latin America 20-Year Perspective for Industrial Enzymes by End-Use Segment - Percentage Breakdown of Dollar Sales for Food & Feed, Detergents, Textiles, Leather, Pulp & Paper, and Others for Years 1991,1995, 2005 & 2010 (includes corresponding Graph/Chart)

IV. COMPETITION

1. Aalto Scientific Ltd. (USA)

2. AB Enzymes GmbH (Germany)

AB Enzymes Oy (Finland)

3. Acca SpA (Italy)

4. Advanced Enzyme Technologies Ltd. (India)

5. Altus Pharmaceuticals, Inc. (USA)

Table 123: Annual Sales Analysis: 2003-2005 (In US$ million)

Table 124: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million)

6. Amano Enzyme, Inc. (Japan)

7. American Biosystems, Inc. (USA)

8. Aureozyme, Inc. (USA)

9. Bachem AG (Switzerland)

Table 125: Half Yearly Sales Analysis: 2005-2006 (H1) (In CHF million)

Table 126: Annual Sales Analysis: 2004-2005 (In CHF million)

Table 127: Annual Sales Analysis by Segment: 2004-2005 (In CHF million)

Table 128: Annual Sales Analysis by Geographic Region: 2004-2005 (In CHF million)

10. BASF Aktiengesellschaft (AG) (Germany)

Table 129: First Quarter Sales Analysis: 2005-2006 (In € billion)

Table 130: Annual Sales Analysis: 2003-2005 (In € billion)

BASF Corporation (USA)

Table 131: Annual Sales Analysis: 2003-2005 (In US$ billion)

11. Beldem SA (Belgium)

12. Biocatalysts, Ltd. (UK)

13. Biocon India Limited (India)

Table 132: Annual Sales Analysis: 2004-2005 (In INR million)

14. Biopole SA (Belgium)

15. Bioproton Pty., Ltd. (Australia)

16. BioResource International (BRI) (USA)

17. Blue Star Chemicals NV (Belgium)

18. Borer Chemie AG (Switzerland)

19. Carif SA (France)

20. Cernol Chemicals Ltd. (Mauritius)

21. Chimica Dr Fr D'agostino SpA (Italy)

22. CHR. Hansen A/S (Denmark)

CHR Hansen SA (France)

CHR. Hansen GmbH (Germany)

23. Chromagen, Inc. (USA)

24. Clariant International Ltd. (Switzerland)

Table 133: Half Yearly Sales Analysis: 2005-2006 (H1) (In CHF million)

Table 134: Half Yearly Sales Analysis by Segment: 2005- 2006 (H1) (In CHF million)

Table 135: Half Yearly Sales Analysis by Geographic Region: 2005-2006 (H1) (In CHF million):

Table 136: Annual Sales Analysis: 2004-2005 (In CHF million)

Table 137: Annual Sales Analysis by Segment: 2004-2005 (In CHF million)

Table 138: Annual Sales Analysis by Geographic Region: 2004-2005 (In CHF million)

Clariant Benelux SA (Belgium)

Clariant Egypt (Egypt)

Clariant SpA (Italy)

25. Danisco A/S (Denmark)

Table 139: Annual Sales Analysis: 2004-2006 (In DKK million)

Table 140: Annual Sales Analysis by Segment: 2005-2006 (In DKK million)

Table 141: Annual Sales Analysis by Geographic Region: 2005-2006 (In DKK million)

Table 142: Annual Sales Analysis by Geographic Region: 2004-2005 (In DKK million)

Genencor International, Inc. (USA)

Danisco Animal Nutrition (USA)

Danisco (Russian Federation)

Danisco Belgium SA-NV (Belgium)

Danisco Czech Republic AS (Czech Republic)

Danisco Deutschland GmbH (Germany)

Danisco Ingredients France Sarl (France)

Danisco Sweden AB (Sweden)

Genencor International Bvba (Belgium)

Genencor International France (France)

Genencor International Oy (Finland)

26. Degussa AG (Germany)

Table 143: Annual Sales Analysis: 2003-2005 (In € million)

Table 144: Annual Sales Analysis by Segment: 2004 - 2005 (In € million)

Degussa Bioactives (Italy)

27. Direvo Biotech AG (Germany)

28. Discoverx Corporation (USA)

29. Diversa Corporation (USA)

Table 145: Half Yearly Sales Analysis: 2004-2005 (H1) (In US$ million)

Table 146: Half Yearly Sales Analysis by Geographic Region: 2005-2006 (In US$ million)

Table 147: Annual Sales Analysis: 2004-2005 (In US$ million)

Table 148: Quarterly Sales Analysis: 2004-2005 (In US$ million)

30. Dow Chemical Company, The (USA)

Table 149: First Quarter Sales Analysis: 2005-2006 (In US$ million)

Table 150: Annual Sales Analysis: 2003-2005 (In US$ million)

Table 151: Annual Sales Analysis by Quarter: 2004-2005 (IN US$ million)

Table 152: Annual Sales Analysis by Segment: 2004-2005 (In US$ million)

Table 153: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million)

31. DSM NV (The Netherlands)

32. Dyadic International, Inc. (USA)

Table 154: Half Yearly Sales Analysis: 2005-2006 (H1) (In US$ million)

Table 155: Half Yearly Sales Analysis by Industry: 2005 -2006 (H1) (In US$ million)

Table 156: Half Yearly Sales Analysis by Geographic Region: 2005-2006 (H1) (In US$ million)

Table 157: Annual Sales Analysis: 2004-2005 (In US$ million)

Table 158: Annual Sales Analysis by Industry: 2004-2005 (In US$ million)

Table 159: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million)

33. E. Begerow GmbH & Co. (Germany)

34. Emilio Peña SA (Spain)

35. Enchira Biotechnology Corporation (USA)

36. Enzbank, Inc. (Korea)

37. Enzymase International SA (Belgium)

38. Enzymatic Deinking Technologies LLC (USA)

39. Enzyme Development Corporation (USA)

40. Esquim SA (Spain)

41. Everstar S.R.O. (Czech Republic)

42. Forventa Ltd. (New Zealand)

43. Gelda Scientific (Canada)

44. Greentech SA (France)

45. Halcyon Proteins Pty., Ltd. (Australia)

46. Hansa Chemie AG (Germany)

47. Hardtech Group SL (Spain)

48. Hasco-Lek (Poland)

49. Hev Chemicals (Germany)

50. Jan Dekker France S.A.R.L. (France)

51. KBI Biopharma, Inc. (USA)

52. Laffort Oenologie (France)

53. Lallemand SA (France)

54. Lyven (France)

55. Maps (India) Ltd. (India)

56. Mauri Yeast Australia Pty., Ltd. (Australia)

57. Maxygen, Inc. (USA)

Table 160: Half Yearly Sales Analysis: 2005-2006 (H1) (In US$ million)

Table 161: Annual Sales Analysis: 2004-2005 (In US$ million)

Table 162: Annual Sales Analysis by Segment: 2004-2005 (In US$ million)

JFC - Julich Fine Chemicals GmbH (Germany)

58. Maybridge PLC (UK)

59. Naturex SA (France)

60. NEXGEN Biotechnologies, Inc. (Korea)

61. Nopco Paper Technology AS (Spain)

62. Novozymes A/S (Denmark)

Table 163: Nine Months Ended Sales Analysis: 2004-2005 (Nine Months Ended, September) (In DKK million)

Table 164: Nine Months Ended Sales Analysis by Segment: 2004-2005 (Nine Months Ended, September) (In DKK million)

Table 165: Nine Months Ended Sales Analysis by Geographic Region: 2004-2005 (Nine Months Ended, September) (In DKK million)

Novozymes, Inc. (USA)

Novozymes Biologicals France SA (France)

Novozymes Switzerland AG (Switzerland)

Novozymes UK Ltd. (UK)

63. Organotechnie SA (France)

64. Palsgaard A/S (Denmark)

65. Pariser Industries, Inc. (USA)

66. PB Gelatins France (France)

67. Prodigene, Inc. (USA)

68. Proeco Químicas S.L. (Spain)

69. Proindiver SA (Spain)

70. RENCO New Zealand (New Zealand)

71. Rintekno Group (Finland)

72. Rohm And Haas Company (USA)

Table 166: First Quarter Sales Analysis: 2005-2006 (In US$ million)

Table 167: First Quarter Sales Analysis: 2005-2006 (In US$ million)

Table 168: First Quarter Sales Analysis by Geographic Region: 2005-2006 (In US$ million)

Table 169: Annual Sales Analysis: 2003-2005 (In US$ million)

Table 170: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million)

Table 171: Annual Sales Analysis by Segment: 2004-2005 (In US$ million)

Table 172: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million)

Rohm And Haas Italia, Srl (Italy)

73. Rossari Biotech Pvt., Ltd. (India)

74. SA Promer (France)

75. Sigma-Aldrich Corporation (USA)

Table 173: First Quarter Sales Analysis: 2005-2006 (In US$ million)

Table 174: Annual Sales Analysis: 2003-2005 (In US$ million)

Table 175: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million)

Table 176: Annual Sales Analysis by Segment: 2004-2005 (In US$ million)

Table 177: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million)

76. Specialty Enzymes And Biochemicals Co. (USA)

77. Super Glanz, SpA (Italy)

78. Synthron (France)

79. Tecnufar Iberica S.L. (Spain)

80. Tergo Industries Ltd. (New Zealand)

81. Valley Research, Inc. (USA)

82. Vialco Ltd. (Cyprus)

83. Zytex Pvt. Ltd. (India)

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