Gene Silencing with RNA Interference: A New Generation of Pharmaceuticals? : Market Research Report

Gene Silencing with RNA Interference: A New Generation of Pharmaceuticals?

Published: Jul. 20, 2006 - 196 Pages

INTRODUCTION: 1. What is RNA Interference (RNAi); 2. How Does RNA Interference Work?; 3. RNA Interference vs. Antisense; 4. Drug Development - RNAi fits where?; 5. RNA Interference Market is Expected to Explode; 6. Advantages of RNAi; 7. Disadvantages; 8. Questions to Answer
ANALYSIS PROCESS: 1. Overview of the Analysis Process; 2. Interpreting an Area Visual Index™ -Visualizing Technology Trends; 3. Interpreting a Company Visual Index™; 4. Interpreting a Company Focus Summary Table; 5. Interpreting a Technology Choices Array (TCA) Chart
ANALYSIS RESULTS: 1. Literature and Scientific Databases; 2. Database Validations; 3. RNAi Patent Database; 4. Publication/Patent Activity Comparison; 5. Overall Focuses from IPC Codes; 6. Patenting Activity Distributions; 7. Partnering Story: RNAi_Group; 8. RNAi Process Flow: Template for Area Analysis; 9. Organizing Patents into Business Relevant Groups; 10. RNA Synthesis: Well Developed Technology; 11. Disease Marker: Heavily Contested Space; 12. Sequence Selection Algorithms & Models; 13. RNAi - Delivery of the Molecule
STRATEGIC VIEW - Technology Choices Array (TCA) Chart: Conclusions from the TCA Chart for Patents; Company Focuses - TCA Chart Views (Top 25 companies)
RNAi_Group
SIRNA
WYETH
UCALIF
LEXICON GENETICS
EI_DUPONT
JOHNS HOPKINS
INCYTE_GENOMICS
AMGEN
EVOTEC NEURO
CHIRON
ONCOTHERAPY SCIENCE
AFFINIUM PHARMACEUTICALS
U.S. GOVT.
GENERAL HOSPITAL
EXELIXIS
DEVELOGEN
U. COLORADO
HARVARD
J&J
BAYLOR
COLUMBIA U
U.PENN
CALIFORNIA INSTITUTE OF_TECH
RIGEL PHARMACEUTICALS
PFIZER
ARES TRADING
ORIGENE_TECH
AVENTIS
CONCLUSIONS: 1. Points of Competition; 2. How will RNAi Technology Evolve?; 3. Escaping the Current Paradigm; 4. RNAi Application Development: Cutting to the Chase; 5. Recommendations
READER’S CHALLENGE
COMMENTS & SUGGESTIONS
ABOUT PATENT INSIGHTS
EXPLANATION OF APPENDIX TABLES
SELECTED REFERENCES
APPENDIX TABLES: Company Focus Summary Table - 25 Most Active Organizations; Company Focus Summary Table - Alphabetical Listing

Abstract

The market for RNA interference (RNAi) both as a research tool and as a new class of pharmaceuticals is projected to explode, but is the technology ready to support the expected growth? The purpose of this report is to map and assess the technology development status of RNAi and to determine which parts of the technology are ready for prime time.

Patent Insights’ report provides technology maps to answer strategic questions.

Is RNAi ready for prime time?
What diseases will RNAi treat?
What technology approaches are hot or cold today?
What barriers will RNAi drugs need to overcome?
How will the technology evolve?
What companies will profit form overcoming them?
What companies will lead the way? Where are they focused?

To complete the assessment, Patent Insights identified trends in technology developments by categorizing ~12000 RNAi related patents into 82 business relevant categories. Supplementing the patent trends with information from ~13000 journal references, Patent Insights was able to assess the significance of the patent trends and to make some educated predictions about the future direction of RNAi technology.

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Gene Silencing with RNA Interference: A New Generation of Pharmaceuticals?

Table of Contents

Abstract