Bioinformatics Markets

Published by: Trimark Publications

Published: Jun. 14, 2006 - 181 Pages

Table of Contents

1. Overview

1.1 Statement of Report

1.2 Objectives of this Report

1.3 Scope of this Report

1.4 Methodology

2. Introduction

2.1 Global Bioinformatics Products Industry

2.2 Computers and Biology

2.2.1 Bioinformatics and the Internet

2.3 Company Evaluation Overview

2.4 Market Outlook

2.4.1 Competitive Structure

2.5 Applications of Bioinformatics

2.5.1 Healthcare

2.5.2.1 Allocation of R&D

2.5.2.2 Traditional Drug Discovery Process

2.5.2.3 Drug Discovery and Informatics

2.5.2.4 Collaborative Agreements

2.6 The Human Genome Project (HGP)

2.6.1 Goals of the Human Genome Project

2.6.2 Benefits of the Human Genome Project

2.7 Barriers to Entry

2.8 Proteomics and Databases

2.8.1 Protein Database Standards

2.8.2 Future Trends

3. The U.S. Bioinformatics Market

3.1 Overview

3.2 Market Revenue and Growth Forecasts

3.3 Market Drivers

4. Genomics

4.1 The Biotechnology Industry

4.2 The Development of a Genomics Market

4.2.1 Market Drivers

4.2.2 Market Restraints

4.2.3 Market Size and Growth Projections

4.2.4 The U.S. Genomics Market

4.3 Biochips and Microarrays

4.3.1 Key Challenges

4.3.2 Freeware

4.3.3 New Tools

4.4 Bioinformatics

4.5 Disease Targets

4.6 Functional Genomics

4.7 Gene Sequencing

4.8 Gene Sequence Variation Detection

4.9 Comparative Genomics

4.10 Genome Database Arrays

4.11 High-throughput Genomics

4.11.1 High-throughput Technology

4.11.2 Lab on a Chip

4.12 Pharmacogenomics

4.13 Probe Arrays

4.13.1 Gene Expression Monitoring Arrays

4.14 DNA Analysis Arrays

4.15 Proteomics

4.16 Sequencing

4.17 Single Nucleotide Polymorphisms (SNPs)

4.18 Structural Genomics

4.19 Photolithography

4.20 Instrumentation

5. The Bioinformatics Industry

5.1 Definition and Role of Bioinformatics

5.1.1 Bioinformatics Sector Overview

5.1.2 The Future Status of Bioinformatics

5.1.3 Barriers to Growth

5.2 Types of Data and Bioinformatics Applications

5.2.1 Validated Core Modeling Technology

5.2.2 Broad Applicability

5.2.3 Data Management Compliant with Industry Standards

5.2.4 Open Architecture

5.2.5 Ease of Use

5.2.6 Increased Access

5.3 Functions of Informatics Software

5.3.1 Data Management

5.3.2 Data Transformation

5.3.3 Data Collaboration

5.3.4 Interface for Online Data Sources

5.4 Target Markets for Informatics Software

5.5 Steps Involved in Bringing a Drug to Market

5.6 Costs Incurred in Developing a New Drug

5.7 Industry Drivers and Challenges

5.8 Industry Risks

5.9 Products of Bioinformatics

5.10 Bioinformatics Processes

5.11 Informatics Tools and Functionalities

5.11.1 Sequence to Structure

5.11.2 Lead Identification and Optimization

5.11.3 Development and Formulation

5.11.4 Improving Materials and Processes

5.11.5 Other Materials-based Industries

5.12 Role of Bioinformatics in the Biotechnology Value Chain

5.13 Bioinformatics Market Segments

5.13.1 Databases

5.13.2 Hardware

5.13.3 Software

5.13.4 Bioinformatics Services

5.14 Bioinformatics Market Size

5.14.1 Sales and R&D

5.14.2 IT Budget

5.14.3 Projected Bioinformatics Market Size

5.14.4 Bioinformatics Market Components

5.15 Bioinformatics Business Models

5.15.1 Changing Business Models

5.15.2 Competition for Pure Play Informatics Companies

5.15.3 Non-Profit Organizations

5.15.4 In-House Bioinformatics Solutions

5.15.5 Large IT Companies

5.16 Bioinformatics Target Disciplines

5.16.1 Comparative Genomics

5.16.2 Pharmacogenomics

5.16.3 Functional Genomics

5.16.4 Proteomics

5.16.5 Structural Genomics

5.16.6 Image Informatics

5.16.7 Clinical Trial Informatics

5.16.8 Cheminformatics

5.17 Bioinformatics Architecture

5.18 Bioinformatics Applications

5.18.1 Data Search Tools

5.18.2 Data Visualization Tools

5.18.3 Data Mining and Clustering

5.18.4 Enterprise Solutions

5.18.5 Data Warehousing

5.19 Evaluation of Bioinformatics Solutions

5.19.1 Requirements of Study

5.19.2 Shortlisting the Options

5.19.3 Scoring Patterns

5.19.4 Performance

5.19.5 Data Storage

5.19.6 Data Management in Drug Discovery

5.19.7 Key Issues in Bioinformatics Data Storage

5.20 Convergence of Industries

5.21 Proteins as a Driver

5.23 Current Bioinformatics Research

5.24 New Bioinformatics Modeling Algorithms

5.25 3D Modeling

5.26 Patenting Bioinformatics Algorithms

6. Recent Industry Activity: Collaborations and Acquisitions

7. Product Development and Launches

8. Global Market Perspective

9. Corporate Profiles

9.1 Accelrys

9.2 Affymetrix, Inc.

9.3 Agencourt Bioscience Corporation

9.4 Agilent Technologies

9.5 AlgoNomics

9.6 ALLEZ Software

9.7 ApoCom Genomics

9.8 Applied Biosystems

9.9 Ariadne Genomics, Inc.

9.10 Array Genetics

9.11 Automated Handling Systems, Inc.

9.12 Avestha Gengraine Technologies Pvt. Ltd.

9.13 Bioalma

9.14 Biobase GmbH

9.15 BioCarta

9.16 Biodatabases (AMITA Corporation)

9.17 BioDiscovery, Inc.

9.18 BioInformatics, LLC

9.19 BioInformatics Services

9.20 BioInformatics Solutions, Inc.

9.21 Biomax Informatics AG

9.22 Bioreason, Inc.

9.23 Biosiris

9.24 BioSoftSolutions

9.25 Biotique Systems, Inc.

9.26 BioWisdom Ltd.

9.27 Bio-Xtal

9.28 Cambridge Antibody Technology

9.29 Cambridge BlueGnome (BlueGnome)

9.30 Capital Genomix

9.31 Celera Genomics

9.32 Cellomics, Inc.

9.33 Cellectis

9.34 CeuticalSoft

9.35 Chemical Computing Group

9.36 Cimarron Software, Inc.

9.37 CLONDIAG Chip Technologies

9.38 CodonCode Corporation

9.39 Cognia Corporation

9.40 CompuDrug

9.41 Compugen Ltd.

9.42 Corimbia

9.43 CSIRO Bioinformatics

9.44 CuraGen Corporation

9.45 CyberGene

9.46 Data Unlimited International

9.47 deCODE Genetics

9.48 Decodon GmbH

9.49 Deltagen, Inc.

9.50 Digilab BioVisioN

9.51 Discovery Partners International, Inc.

9.52 DNA Software, Inc.

9.53 DNAPrint Genomics, Inc.

9.54 DNA Star, Inc.

9.56 DxS Genotyping, Ltd.

9.57 Electric Genetics, Pvt. Ltd.

9.58 Entelos

9.59 Epigenomics, AG

9.60 Epitope Informatics, Ltd.

9.61 e-Proteomics.net

9.62 EraGen Biosciences

9.63 Essential Informatics

9.64 European Bioinformatics Institute (EBI) Industry Programme

9.65 Evolutionary BioInformatics

9.66 Genamics

9.67 Genebio

9.68 Gene Biotechnologies

9.69 GeneData, AG

9.70 Gene-IT

9.71 Gene Logic, Inc.

9.72 GenOdyssee, SA

9.73 Genolyze

9.74 Genomatica

9.75 Genomics Collaborative

9.76 Genomic Solutions Inc.

9.77 Genomining

9.78 Geospiza, Inc.

9.79 Glycominds

9.80 Health Discovery Corporation

9.81 Hitachi Corporate Technology Group

9.82 Improved Outcomes Software, Inc.

9.83 INCOGEN, Inc.

9.84 Incyte Corporation

9.85 Informagen

9.86 Inpharmatica

9.87 Insightful Corporation

9.88 Insilico Software

9.89 Insilicos

9.90 Intrexon Corporation

9.91 Invenio Biosolutions

9.92 Invitrogen Corporation

9.93 IO Informatics

9.94 Kshema Technologies Ltd.

9.95 LabBook

9.96 LabVantage Solutions

9.97 Lifespan Biosciences

9.98 Lion Bioscience, AG

9.99 MathEcology LLC

9.100 Matrix Science

9.101 Medicel, Ltd.

9.102 METabolic EXplorer

9.103 Metahelix Life Sciences

9.104 Metalife

9.105 Monogram Biosciences, Inc.

9.106 Neurome, Inc.

9.107 Nonlinear Dynamics

9.108 Ocimum Biosolutions

9.109 OmniViz, Inc.

9.110 Partek Inc.

9.111 Perlegen Inc.

9.112 Prokaria

9.113 Quantiom Bioinformatics

9.114 Relevant Software, Inc.

9.115 Rosetta Inpharmatics

9.116 SBI Science LLC

9.117 Seascape Learning

9.118 Spotfire, U.S. Headquarters

9.119 Spotfire AB, European Headquarters

9.120 Spotfire, Japan Headquarters

9.121 Strand Life Sciences Pvt. Ltd.

9.122 Sun Microsystems

9.123 Syngene

9.124 Tahoe Informatics

9.125 3rd Millennium, Inc.

9.126 Thomson Scientific

9.127 TIB MOLBIOL

9.128 Tripos, Inc.

9.129 United Bioinformatica, Inc.

9.130 VizXLabs

INDEX OF FIGURES

Figure 4.1: Global Biotechnology Industry

Figure 5.1: Informatics Applications along the Drug-Discovery Value Chain

Figure 5.2: Functions of Bioinformatics Software in Research

Figure 5.3: Growth of GenBank, 1982-2002

Figure 5.4: EMBL Database Growth, 1991-2003

Figure 5.5: Steps Involved in Bringing a Drug to Market

Figure 5.6: Analysis of the Total Costs in Developing a New Drug

Figure 5.7: Role of Bioinformatics in the Biotechnology Value Chain

Figure 5.8: Worldwide Projected Pharmaceutical Sales and R&D Expenditure, 2000-2010

Figure 5.9: Worldwide Projected Growth in IT Budget, 2000-2010

Figure 5.10: Worldwide Projected Bioinformatics Market, 2000-2010

Figure 5.11: Worldwide Bioinformatics Market Vendor Components, 2000-2010

Figure 5.12: Steps of a Proteomics Experiment

Figure 5.13: Bioinformatics Architecture

INDEX OF TABLES

Table 2.1: Leading Biotechnology Companies

Table 2.2: Pharmaceutical R&D Expenditures by World Region, 1990-2003

Table 2.3: Total of Domestic U.S. R&D and R&D Abroad, Ethical Pharmaceuticals, Research-Based Pharmaceutical Companies, 1980-2003

Table 2.4: Global Pharmaceutical R&D Expenditures, 1993-2004

Table 2.5: SIB Informatics Databases

Table 4.1: The U.S. Biotechnology Industry Size and Revenue, 1995-2005

Table 4.2: Global Biotechnology Industry Major Segments

Table 4.3: Genomics Sector Market Size, 2001-2008

Table 4.4: The Biochip Array Market, 2000-2010

Table 4.5: Selected Competitors in the Biochip Market

Table 4.6: Biochip Microarray Products

Table 4.7: Bioinformatics Tools

Table 4.8: Functional Genomics Companies Building Advanced Integrated Platforms and Substantial Databases

Table 4.9: Companies Using New Genomic Tools

Table 4.10: Non-DNA Based Chip Suppliers

Table 4.11: Robotics or “Lab-on-a-Chip” Market Sector

Table 4.12: Key High-Throughput and Systemic Approaches for Genomic Analysis

Table 4.13: Total Biochip Market, 2002-2010

Table 4.14: Pharmacogenomics Segment Players

Table 4.15: The Worldwide Market for Pharmacogenomics, 2000-2008

Table 4.16: Competitors in the SNP Genotyping Segment

Table 4.17: Scanning and Detection Technology Suppliers

Table 5.1: Data Sources and Bioinformatic Investigations

Table 5.2: Drivers and Challenges of the Bioinformatics Industry

Table 5.3: Bioinformatics Activities, Sub-Activities and Key Players

Table 5.4: Alliances between IT/Telecom and Biotechnology Firms

Table 5.5: Types of Intellectual Property Protection for Bioinformatics Tools

Table 8.1: Bioinformatics Market Size, 2000-2010

Table 8.2: Cheminformatics Market Size, 2004-2010

Table 8.3: In-silico Informatics Market Size, 2004-2010

Table 8.4: Bioinformatics Hardware and Systems Market Size, 2004-2010

Abstract

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