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World Pharmacogenomics - Future of Healthcare Industry 2009™

Published by: Venn Research, Inc.

Published: Mar. 1, 2006 - 65 Pages


Table of Contents



1. ASSESSING PHARMACOGENOMICS TECHNOLOGY AND PHARMACEUTICAL INDUSTRY




1.1. THE PHARMACEUTICAL INDUSTRY TODAY

1.2. BLOCKBUSTER DRUG SALES BY PHARMACEUTICAL SECTOR (2005)

1.3. COST OF DRUG DISCOVERY AND PHARMACOGENOMICS

1.4. FUTURE OF PHARMACOGENOMICS IN DRUG DEVELOPMENT




2. GLOBAL MARKET FOR PHARMACOGENOMICS DEVICES AND DIAGNOSTIC TOOLS




2.1. MARKET FOR MICROARRAYS (2004-2009)

2.1.1 Types of Microarrays

2.1.1.1 Nanochip Arrays

2.1.1.2 Bead Arrays

2.1.1.3 Nanoparticles Arrays

2.1.2 Market Demand for Microarrays in Pharmacogenomics

2.2. MARKET FOR PCR ARRAYS (2004-2009)

2.2.1 Types of PCR Array Technologies

2.2.1.1 LightCycler

2.2.1.2 TaqMan Technology

2.2.1.3 Invader

2.2.1.4 ReadIt Depolymerixation Assay

2.2.1.5 Tag-It Mutation Assay

2.2.2 Market Demand for PCR-Assays (2004-2009)

2.3. IN SITU ANALYSIS




3. DEMAND FOR PHARMACOGENOMICS TREATMENT, BY DISEASE APPLICATIONS (2004-2009)




3.1. CARDIOVASCULAR DISEASE

3.2. BREAST CANCER

3.3. LEUKEMIA

3.4. HIV/AIDS

3.5. GENETIC RESISTANCE TESTING AND PHARMACOGENOMICS




4. PHARMACOGENOMICS PATENT ANALYSIS AND IPO




4.1. PHARMACOGENOMICS PATENTS, BY APPLICATION CATEGORY

4.2. PHARMACOGENOMICS PATENTS, BY DISEASE

4.3. PHARMACOGENOMICS PATENTS, BY REGIONAL DISTRIBUTION




5. PHARMACOGENOMICS RESEARCH AND APPLICATION, BY REGION




5.1. UNITED STATES

5.2. EUROPEAN UNION

5.3. JAPAN

5.4. OTHER REGIONS




6. PHARMACOGENOMICS AND DRUG METABOLISM




6.1. DRUG METABOLISM BY CYTOCHROMES

6.2. P-450 ISOZYMES AND PHARMACEUTICALS

6.2.1 P450 Isozyme CYP3A

6.2.2 P450 Isozyme CYP2D6

6.2.3 P450 Isozyme CYP2C9

6.2.4 P450 Isozyme 2C19

6.2.5 P450 Isozyme 1A2

6.3. GLOBAL MARKET FOR AMPLICHIP ARRAYS

6.4. COMPETITION WITH PHENOTYPIC ASSAY




7. COMPANY PROFILES




7.1. AFFYMETRIX INC.

7.1.1 Sales Revenue by Region and Product Type, 2005

7.1.2 Research and Development Expenses

7.1.3 New Products Launches and Issues

7.2. AGILENT TECHNOLOGIES, INC.

7.2.1 Sales and Revenue, By Region and Types of Products 2004

7.2.2 Research And Development Expenses

7.2.3 New Product Launches and Initiatives

7.3. THIRD WAVE TECHNOLOGIES, INC

7.3.1 Sales and Revenue, By Region and Product Type 2004

7.3.2 Research and Development Revenues

7.3.3 Products Launches and Initiatives

7.4. NANOGEN INC.

7.4.1 Sales and Revenue, by Region and Product Type, 2004

7.4.2 Research and Development Revenues

7.4.3 Product Launches and Initiatives

7.5. OTHER COMPETITORS

7.5.1 Applied Biosystems

7.5.2 GE Healthcare

7.5.3 Sequenom Inc.

7.5.4 Molecular Devices Corporation

7.5.5 Illumina

7.5.6 Incyte Corporation

7.5.7 deCODE genetics, Inc.

7.5.8 Caliper Life Sciences

7.5.9 Orchid BioSciences, Inc.

7.5.10 Beckman Coulter, Inc.

7.5.11 Quest Diagnostics Incorporated




List of Figures:




Figure 1:1 - Total Pharmaceutical Excipients Market Revenue, In %Age, 2004-2008

Figure 1:2 - Cost Of Developing New Drugs, In Percentage, 2005

Figure 1:3 - Attrition Rates Of New Compounds In The Drug Development Processes, In %Age, 2004

Figure 1:4 - How Pharmacogenomics Can Streamline Future Clinical Trials

Figure 2:1 - Demand For Pharmacogenomics Diagnostic Tools Worldwide, By Type, 2004-2009

Figure 2:2: World Biochips Market, In Billion Dollars, 2001-2009

Figure 2:3 - World Market For Microarrays In Pharmacogenomics By Type, In ($Million), 2001-2009

Figure 2:4 - World Market For Pcr-Assays In Pharmacogenomics By Type, In ($Million), 2001-2009

Figure 3:1 - Number Of Cardiovascular Death, By Gender (Deaths Per 100,000 Population), 2000-2005

Figure 3:2 - World Statin Market Value, In Billion Dollars, 2005-2009

Figure 3:3 - Estimated Breast Cancer Cases/Deaths Worldwide, By Region, Per 100, 000 Population (2000-2004)

Figure 3:4 - World Market For Herceptin, By Region, ($ Millions), 2001-2009

Figure 3:5 - Leukemia Survival Rates, By Type, In Percentage Change, 2005

Figure 3:6- Regional Statistics For Hiv & Aids, End Of 2005, In Millions

Figure 3:7-Market For Hiv Resistance Testing Worldwide, By Region, ($ Million) 2003-2009

Figure 4:1-Number Of Pharmacogenomics Patents Filed And %Age Share, By Technology - 2005

Figure 4:2-Number Of Patents Application Filed, By Disease Target, 2005

Figure 4:3-Total Pharmacogenomics Patents By Assignee, January 2004- January 2005

Figure 4:4-Number Of Patents Filed, By Region (In Percentage), 2005

Figure 6:1-Drug Metabolism Enzymes And Frequency Of Their Mutations In Ethnic Population

Figure 6:2-Major Cytochrome P450 Isozymes

Figure 6:3-Global Market For Amplichip Arrays In Diagnostic Use By Region, Through 2009 ($ Millions)




List of Tables:




Table 1:1 - Blockbuster Drug Sales, By Major Pharmaceutical Companies, 2004

Table 2:1 - World Market For Microarrays In Pharmacogenomics By Type, Through 2009 (Aagr %Age)

Table 2:2: World Market For Pcr-Assays, By Type, 2001-2009 (Aagr %Age)

Table 2:3 - World Market For In Situ, By Type, 2001-2009 (Aagr %Age)

Table 3:1 - Total Number Of Cardiovascular Cases Diagnosed And Reported Death, 2005

Table 3:2 - Leading Products In 2004 By Global Pharmaceutical Sales

Table 3:3 - World Gleevec Market Value, By Region, In Million Dollars, 2001-2009

Table 3:4 - Market For Hiv Resistance Testing Worldwide, By Region, (Aagr %Age) 2003-2009

Table 6:1 - World Market For Amplichip-Assays, By Type, 2001-2009 (Aagr %Age)

Table 7:1 - Affymetrix Inc. Sales Revenue By Region And Product Type, 2004

Table 7:2 - Research Revenue, For Three Months Ended September 30, 2004-2005, In Millions

Table 7:3 - Agilent Technologies Inc., Sales Revenue By Region And Product Type, 2004

Table 7:4 - Research Revenue, For Three Months Ended July 31, 2004-2005, In Millions

Table 7:5 - Third Wave Technologies., Sales Revenue By Region And Product Type, 2004

Table 7:6 - Third Wave Technologies Research Revenue, For Three Months Ended September 31, 2004-2005, In Millions

Table 7:7 - Nanogen Sales Revenue By Region And Product Type, 2004

Table 7:8 - Nanogen Research Revenue, For Three Months Ended September31, 2004-2005, In Millions

Abstract

Venn’s study on World Pharmacogenomics — Future of Healthcare Industry 2009™ include the identification of novel genomic targets for drug development, the clinical applications of genomics science, potential benefits of pharmacogenomics, effect of genetic variability on drug toxicity and efficacy.

Importantly, this market research report integrate new developments in genomics and proteomics to clinical medicine, pharmacology, and therapeutics and assess the trends, developments and challenges that the industry faces.

Venn Research, in association to its network of partners provides information and research to thousands of clients worldwide. The information provided herein has been obtained from reliable sources to provide a holistic survey on the market dynamics.

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