Providing market research reports, industry analysis, company profiles and country reports for strategic planning, competitive intelligence, marketing and business research.
Search for Market Research Reports:    

Global Markets for Alzheimer's Disease Medications

Published by: Millennium Research

Published: Apr. 1, 2005


Table of Contents



EXECUTIVE SUMMARY




METHODOLOGY




1.0 AD OVERVIEW

1.1 Definition of AD

1.1.1 Symptoms

1.1.2 Diagnosis

1.2 Segmentation of AD

1.3 Prevalence of AD

1.4 Unmet Needs in AD

1.5 Market Analyses Assumptions

1.5.1 Generic Competition

1.5.2 UK Forecasts

1.5.3 Mild to Moderate Market Assumptions

1.5.4 Moderate to Severe Market Assumptions

1.6 Market Analysis

1.6.1 US Market Forecast

1.6.2 European Market Forecast

1.6.3 Japanese Market Forecast

1.7 Competitive Analysis

1.8 Drugs That Address Associated Conditions

1.9 AD Research and Development

1.9.1 ACh Modulators

1.9.2 Neuroprotective and Neurotrophic Drugs

1.9.3 Beta-Amyloid Modulators

1.9.4 Beta-Secretase Inhibitors

1.9.5 Other Compounds Under Development for AD

1.9.6 Application of Existing Products to AD

1.9.7 Innovative Approaches




2.0 AD PATIENT POPULATION

2.1 Definition of AD

2.1.1 Epidemiology

2.1.1.1 Clinical Investigations

2.1.2 Symptoms

2.1.3 Diagnosis

2.1.3.1 Psychological Testing

2.2 Segmentation of AD

2.2.1 Mild to Moderate Forms of AD

2.2.1.1 Mild Cognitive Impairment

2.2.2 Moderate to Severe Forms of AD

2.3 AD Prevalence

2.3.1 Mild to Moderate AD Prevalence

2.3.1.1 Mild to Moderate AD Prevalence in US

2.3.1.2 Mild to Moderate AD Prevalence in Europe

2.3.1.3 Mild to Moderate AD Prevalence in Japan

2.3.2 Moderate to Severe AD Prevalence

2.3.2.1 Moderate to Severe AD Prevalence in the US

2.3.2.2 Moderate to Severe AD Prevalence in Europe

2.3.2.3 Moderate to Severe AD Prevalence in Japan

2.4 Treated AD Patients

2.5 Average Selling Prices

2.6 Unmet Needs in Diagnosis and Treatment of AD

2.6.1 Unmet Needs in the Diagnosis and Treatment of AD in the US

2.6.1.1 US Health Care Structure

2.6.1.2 Issues Specific to AD Patients

2.6.2 Unmet Needs in the Diagnosis and Treatment of AD in Europe

2.6.2.1 European Health Care Structure

2.6.2.2 Issues Specific to AD Patients

2.6.3 Unmet Needs in the Diagnosis and Treatment of AD in Japan

2.6.3.1 Japanese Health Care Structure

2.6.3.2 Issues Specific to AD Patients




3.0 MILD TO MODERATE AD MARKET

3.1 Market Overview

3.2 Mild to Moderate AD Drugs

3.2.1 Cognex

3.2.1.1 Cognex Clinical Results

3.2.1.2 Cognex Formulation, Dosing, and Compliance

3.2.2 Aricept (Memac)

3.2.2.1 Aricept Clinical Results

3.2.2.2 Aricept Formulation, Dosing and Compliance

3.2.3 Exelon (Prometax)

3.2.3.1 Exelon Clinical Results

3.2.3.2 Exelon Formulation, Dosing, and Compliance

3.2.4 Reminyl

3.2.4.1 Reminyl Clinical Results

3.2.4.2 Reminyl Formulation, Dosing and Compliance

3.3 Market Analysis

3.3.1 US Market Forecast

3.3.2 European Market Forecast

3.3.3 Japanese Market Forecast

3.4 Competitive Analysis




4.0 MODERATE TO SEVERE AD MARKET

4.1 Market Overview

4.2 Moderate to Severe AD Drugs

4.2.1 Namenda

4.2.1.1 Namenda Clinical Results

4.2.1.2 Namenda Formulation, Dosing and Compliance

4.2.2 Axura

4.2.2.1 Axura Clinical Results

4.2.2.2 Axura Formulation, Dosing, and Compliance

4.2.3 Ebixa

4.2.3.1 Ebixa Clinical Results

4.2.3.2 Ebixa Formulation, Dosing, and Compliance

4.3 Market Analysis

4.3.1 US Market Forecast

4.3.2 European Market Forecast

4.3.3 Japanese Market Forecast

4.4 Competitive Analysis




5.0 RESEARCH AND DEVELOPMENT

5.1 AD Research Overview

5.1.1 ACh Modulators

5.1.1.1 ACh Modulators Drug Overview

5.1.1.2 ACh Modulators Drug Clinical Trial Data

5.1.1.3 ACh Modulators Drug Candidates by Clinical Stage

5.1.2 Neuroprotective and Neurotrophic Drugs

5.1.2.1 Neuroprotective and Neurotrophic Drug Overview

5.1.2.2 Neuroprotective and Neurotrophic Drug Clinical Trial Data

5.1.2.3 Neuroprotective and Neurotrophic Drug Candidates by Clinical Stage

5.1.3 Beta-Amyloid Modulators

5.1.3.1 Beta-Amyloid Modulators Overview

5.1.3.2 Beta-Amyloid Modulators Clinical Trial Data

5.1.3.3 Beta-Amyloid Modulator Drug Candidates by Clinical Stage

5.1.4 Beta-Secretase Inhibitors

5.1.4.1 Beta-Secretase Inhibitor Drug Overview

5.1.4.2 Beta Secretase (BACE) Inhibitor Clinical Trial Data

5.1.4.3 Beta-Secretase (BACE) Inhibitor Drug Candidates by Clinical Stage

5.1.5 Other Drugs Under Development for AD

5.1.5.1 NMDA Receptor Antagonists

5.1.5.2 Phospholipid-Based Drugs

5.1.5.3 L-Type Calcium Channel Modulators

5.1.5.4 PDE-4 Compounds

5.1.5.5 Ampakine Compounds

5.1.5.6 Protein Deposition Inhibitors Overview

5.1.6 Application of Existing Products to AD

5.1.6.1 Statins

5.1.6.2 Antioxidants

5.1.6.3 Hormones

5.1.6.4 Lithium

5.1.6.5 Rosiglitazone

5.1.6.6 Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

5.1.6.7 Anti-Hypertensives

5.1.6.8 Rasagilene

5.1.6.9 HT Agonists

5.1.6.10 Valproate

5.1.7 Innovative Approaches

5.1.7.1 Gene Therapy

5.1.7.2 Vaccines

5.2 Companies Involved in AD Research

5.2.1 Eli Lilly

5.2.2 Pfizer/Eisai

5.2.3 Sanofi-Aventis

5.2.4 Axonyx

5.2.5 Nymox

5.2.6 Prana Biotechnology

5.2.7 Neurochem

5.3 Discontinued Development Projects

5.3.1 ProMem — Bayer

5.3.2 Viviq — Aventis




APPENDIX A: MRG ACRONYMS AND INITIALISMS




List of Exhibits




EXECUTIVE SUMMARY

Exhibit ES-1: AD Drug Market, by Region, Global, (US$), 2003-2009

Exhibit ES-2: AD Prevalence Rates, by Region and Disease Stage, Global, 2004. ES-3

Exhibit ES-3: Treated AD Patients, by Region, Global, 2003-2009

Exhibit ES-4: ASP per Patient, by Region, Global, (US$), 2003-2009

Exhibit ES-5: Mild to Moderate AD Drug Market, by Brand, Global, (US$), 2003-2009

Exhibit ES-6: Memantine Marketing Rights, by Region, Brand, and Company, Global, 2004

Exhibit ES-7: Moderate to Severe AD Drug Market, as a % of Total, by Region, Europe, 2004 versus 2009

Exhibit ES-8: Leading Competitors in the AD Drug Market, Global, 2004




CHAPTER 1: AD OVERVIEW

Exhibit 1-1: AD Prevalence Rates, by Region and Disease Stage, Global, 2004

Exhibit 1-2: Availability of AD Drug Medications, by Region Global, Q1 2005

Exhibit 1-3: AD Drug Market, by Region, Global, (US$), 2003-2009 (Tabular Format)

Exhibit 1-4: AD Drug Market, by Region, Global, (US$), 2003-2009 (Graphical Format)

Exhibit 1-5: AD Drug Market, by Brand, Global, (US$), 2003-2009 (Tabular Format)

Exhibit 1-6: AD Drug Market, by Brand, Global, (US$), 2003-2009 (Graphical Format)

Exhibit 1-7: AD Drug Market, by Brand, US, (US$), 2003-2009 (Tabular Format)

Exhibit 1-8: AD Drug Market, by Brand, US, (US$), 2003-2009 (Graphical Format)

Exhibit 1-9: AD Drug Market, by Region, Europe, (US$), 2003-2009

Exhibit 1-10: AD Drug Market, by Region, Europe, (€), 2003-2009

Exhibit 1-11: AD Drug Market, by Region, as a % of Total, Europe, 2003-2009 (Tabular Format)

Exhibit 1-12: AD Drug Market, by Region, as a % of Total, Europe, 2003-2009 (Graphical Format)

Exhibit 1-13: AD Drug Market, by Brand, Europe, (US$), 2003-2009 (Tabular Format)

Exhibit 1-14: AD Drug Market, by Brand, Europe, (€), 2003-2009

Exhibit 1-15: AD Drug Market, by Brand, Europe, (US$), 2003-2009 (Graphical Format)

Exhibit 1-16: AD Drug Market, by Brand, France, (US$), 2003-2009

Exhibit 1-17: AD Drug Market, by Brand, France, (€), 2003-2009

Exhibit 1-18: AD Drug Market, by Brand, Germany, (US$), 2003-2009

Exhibit 1-19: AD Drug Market, by Brand, Germany, (€), 2003-2009

Exhibit 1-20: AD Drug Market, by Brand, UK, (US$), 2003-2009

Exhibit 1-21: AD Drug Market, by Brand, UK, (€), 2003-2009

Exhibit 1-22: AD Drug Market, by Brand, UK, (£), 2003-2009

Exhibit 1-23: AD Drug Market, by Brand, Italy, (US$), 2003-2009

Exhibit 1-24: AD Drug Market, by Brand, Italy, (€), 2003-2009

Exhibit 1-25: AD Drug Market, by Brand, Spain, (US$), 2003-2009

Exhibit 1-26: AD Drug Market, by Brand, Spain, (€), 2003-2009

Exhibit 1-27: AD Drug Market, by Brand, Japan, (US$), 2003-2009 (Tabular Format)

Exhibit 1-28: AD Drug Market, by Brand, Japan, (¥), 2003-2009

Exhibit 1-29: AD Drug Market, by Brand, Japan, (US$), 2003-2009 (Graphical Format)

Exhibit 1-30: Leading Competitors in the AD Drug Market, by Region, Global, 2004

Exhibit 1-31: Leading Competitors in the AD Drug Market, Global, 2004

Exhibit 1-32: Leading Competitors in the AD Drug Market, by Region, Europe, 2004

Exhibit 1-33: Leading Competitors in the AD Drug Market, Europe, 2004

Exhibit 1-34: Leading Competitors in the AD Drug Market, Market Value and Market Shares, (US$), Global, 2004

Exhibit 1-35: Leading Competitors in the AD Drug Market, Market Value and Market Shares, (US$), US, 2004

Exhibit 1-36: Leading Competitors in the AD Drug Market, Market Value and Market Shares, Europe, 2004

Exhibit 1-37: Leading Competitors in the AD Drug Market, Market Value and Market Shares, France, 2004

Exhibit 1-38: Leading Competitors in the AD Drug Market, Market Value and Market Shares, Germany, 2004

Exhibit 1-39: Leading Competitors in the AD Drug Market, Market Value and Market Shares, UK, 2004

Exhibit 1-40: Leading Competitors in the AD Drug Market, Market Value and Market Shares, Italy, 2004

Exhibit 1-41: Leading Competitors in the AD Drug Market, Market Value and Market Shares, Spain, 2004




CHAPTER 2: AD PATIENT POPULATION

Exhibit 2-1: GDS AD Classification Framework

Exhibit 2-2: AD Prevalence, by Region and Disease Stage, Global, 2004 (Tabular Format)

Exhibit 2-3: AD Prevalence, by Region and Disease Stage, Global, 2004 (Graphical Format)

Exhibit 2-4: AD Prevalence Rates, by Region, Global, 2004

Exhibit 2-5: AD Prevalence, by Region, Global, 2003-2009 (Tabular Format)

Exhibit 2-6: AD Prevalence, by Region, Global, 2003-2009 (Graphical Format)

Exhibit 2-7: AD Prevalence, by Region, Europe, 2003-2009 (Tabular Format)

Exhibit 2-8: AD Prevalence, by Region, Europe, 2003-2009 (Graphical Format)

Exhibit 2-9: Mild to Moderate AD Prevalence, by Region, Global, 2003-2009 (Tabular Format)

Exhibit 2-10: Mild to Moderate AD Prevalence, by Region, Global, 2003-2009 (Graphical Format)

Exhibit 2-11: Mild to Moderate AD Prevalence, by Region, Europe, 2003-2009 (Tabular Format)

Exhibit 2-12: Mild to Moderate AD Prevalence, by Region, Europe, 2003-2009 (Graphical Format)

Exhibit 2-13: Moderate to Severe AD Prevalence, by Region, Global, 2003-2009 (Tabular Format)

Exhibit 2-14: Moderate to Severe AD Prevalence, by Region, Global, 2003-2009 (Graphical Format)

Exhibit 2-15: Moderate to Severe AD, by Region, Europe, 2003-2009 (Tabular Format)

Exhibit 2-16: Moderate to Severe AD, by Region, Europe, 2003-2009 (Graphical Format)

Exhibit 2-17: AD Treatment Rates, as % of AD Prevalence, by Region, Global, 2003-2009

Exhibit 2-18: Treated AD Patients, by Region, Global, 2003-2009 (Tabular Format)

Exhibit 2-19: Treated AD Patients, by Region, Global, 2003-2009 (Graphical Format)

Exhibit 2-20: Treated AD Patients, by Region, Europe, 2003-2009 (Tabular Format)

Exhibit 2-21: Treated AD Patients, by Region, Europe, 2003-2009 (Graphical Format)

Exhibit 2-22: ASP per Patient, by Region, Global, (US$), 2003-2009 (Tabular Format)

Exhibit 2-23: ASP per Patient, by Region, Global, (Local Currencies), 2003-2009

Exhibit 2-24: ASP per Patient, by Region, Global, (US$), 2003-2009 (Graphical Format)

Exhibit 2-25: ASP per Patient, by Region, Europe, (US$), 2004




CHAPTER 3: MILD TO MODERATE AD MARKET

Exhibit 3-1: Mild to Moderate AD Drug Market, Global, (US$), 2003-2009

Exhibit 3-2: Availability of Mild to Moderate AD Drugs, by Brand, Global, 2004

Exhibit 3-3: Selected New Mild to Moderate AD Medications, Global, 2003-2009

Exhibit 3-4: Mild to Moderate AD Drug Market, by Region, Global, (US$), 2003-2009 (Tabular Format)

Exhibit 3-5: Mild to Moderate AD Drug Market, by Region, Global, (US$), 2003-2009 (Graphical Format)

Exhibit 3-6: Mild to Moderate AD Drug Market, by Brand, Global, (US$), 2003-2009 (Tabular Format)

Exhibit 3-7: Mild to Moderate AD Drug Market, by Brand, Global, (US$), 2003-2009 (Graphical Format)

Exhibit 3-8: Mild to Moderate AD Drug Market, by Brand, US, (US$), 2003-2009 (Tabular Format)

Exhibit 3-9: Mild to Moderate AD Drug Market, by Brand, US, (US$), 2003-2009 (Graphical Format)

Exhibit 3-10: Mild to Moderate AD Drug Market, by Region, Europe, (US$), 2003-2009

Exhibit 3-11: Mild to Moderate AD Drug Market, by Region, Europe, (€), 2003-2009

Exhibit 3-12: Mild to Moderate AD Drug Market, by Region, as a % of Total, Europe, 2003-2009

Exhibit 3-13: Mild to Moderate AD Drug Market, by Region, as a % of Total, Europe, 2004

Exhibit 3-14: Mild to Moderate AD Drug Market, by Brand, Europe, (US$), 2003-2009 (Tabular Format)

Exhibit 3-15: Mild to Moderate AD Drug Market, by Brand, Europe, (€), 2003-2009

Exhibit 3-16: Mild to Moderate AD Drug Market, by Brand, Europe, (US$), 2003-2009 (Graphical Format)

Exhibit 3-17: Mild to Moderate AD Drug Market, by Brand, France, (US$), 2003-2009

Exhibit 3-18: Mild to Moderate AD Drug Market, by Brand, France, (€), 2003-2009

Exhibit 3-19: Mild to Moderate AD Drug Market, by Brand, Germany, (US$), 2003-2009

Exhibit 3-20: Mild to Moderate AD Drug Market, by Brand, Germany, (€), 2003-2009

Exhibit 3-21: Mild to Moderate AD Drug Market, by Brand, UK, (US$), 2003-2009

Exhibit 3-22: Mild to Moderate AD Drug Market, by Brand, UK, (€), 2003-2009

Exhibit 3-23: Mild to Moderate AD Drug Market, by Brand, UK, (£), 2003-2009

Exhibit 3-24: Mild to Moderate AD Drug Market, by Brand, Italy, (US$), 2003-2009

Exhibit 3-25: Mild to Moderate AD Drug Market, by Brand, Italy, (€), 2003-2009

Exhibit 3-26: Mild to Moderate AD Drug Market, by Brand, Spain, (US$), 2003-2009

Exhibit 3-27: Mild to Moderate AD Drug Market, by Brand, Spain, (€), 2003-2009

Exhibit 3-28: Mild to Moderate AD Drug Market, by Brand, Japan, (US$), 2003-2009 (Tabular Format)

Exhibit 3-29: Mild to Moderate AD Drug Market, by Brand, Japan, (¥), 2003-2009

Exhibit 3-30: Mild to Moderate AD Drug Market, by Brand, Japan, (US$), 2003-2009 (Graphical Format)

Exhibit 3-31: Leading Competitors in the Mild to Moderate AD Drug Market, by Region, Global, 2004

Exhibit 3-32: Leading Competitors in the Mild to Moderate AD Drug Market, Global, 2004

Exhibit 3-33: Leading Competitors in the Mild to Moderate AD Drug Market, by Region, Europe, 2004

Exhibit 3-34: Leading Competitors in the Mild to Moderate AD Drug Market, Europe, 2004




CHAPTER 4: MODERATE TO SEVERE AD MARKET

Exhibit 4-1: Moderate to Severe AD Drug Market, by Region, Global, (US$), 2003-2009 (Graphical Format)

Exhibit 4-2: Memantine Marketing Rights, by Region, Brand, and Company, Global, 2004

Exhibit 4-3: Anticipated Medications for Treatment of Moderate to Severe AD, Global, 2003-2009

Exhibit 4-4: Moderate to Severe AD Drug Market, by Region, Global, (US$), 2003-2009 (Tabular Format)

Exhibit 4-5: Moderate to Severe AD Drug Market, by Brand, Global, (US$), 2003-2009

Exhibit 4-6: Moderate to Severe AD Drug Market, by Brand, as a % of Total, Global, 2004 versus 2009

Exhibit 4-7: Moderate to Severe AD Drug Market, by Brand, US, (US$), 2003-2009 (Tabular Format)

Exhibit 4-8: Moderate to Severe AD Drug Market, by Brand, US, (US$), 2003-2009 (Graphical Format)

Exhibit 4-9: Moderate to Severe AD Drug Market, by Region, Europe, (US$), 2003-2009

Exhibit 4-10: Moderate to Severe AD Drug Market, by Region, Europe, (€), 2003-2009

Exhibit 4-11: Moderate to Severe AD Drug Market, by Region, as a % of Total, Europe, 2003-2009 (Tabular Format)

Exhibit 4-12: Moderate to Severe AD Drug Market, by Region, as a % of Total, Europe, 2003-2009 (Graphical Format)

Exhibit 4-13: Moderate to Severe AD Drug Market, by Brand, Europe, (US$), 2003-2009 (Tabular Format)

Exhibit 4-14: Moderate to Severe AD Drug Market, by Brand, Europe, (€), 2003-2009

Exhibit 4-15: Moderate to Severe AD Drug Market, by Brand, Europe, (US$), 2003-2009 (Graphical Format)

Exhibit 4-16: Moderate to Severe AD Drug Market, by Brand, France, (US$), 2003-2009

Exhibit 4-17: Moderate to Severe AD Drug Market, by Brand, France, (€), 2003-2009

Exhibit 4-18: Moderate to Severe AD Drug Market, by Brand, Germany, (US$), 2003-2009

Exhibit 4-19: Moderate to Severe AD Drug Market, by Brand, Germany, (€), 2003-2009

Exhibit 4-20: Moderate to Severe AD Drug Market, by Brand, UK, (US$), 2003-2009

Exhibit 4-21: Moderate to Severe AD Drug Market, by Brand, UK, (€), 2003-2009

Exhibit 4-22: Moderate to Severe AD Drug Market, by Brand, UK, (£), 2003-2009

Exhibit 4-23: Moderate to Severe AD Drug Market, by Brand, Italy, (US$), 2003-2009

Exhibit 4-24: Moderate to Severe AD Drug Market, by Brand, Italy, (€), 2003-2009

Exhibit 4-25: Moderate to Severe AD Drug Market, by Brand, Spain, (US$), 2003-2009

Exhibit 4-26: Moderate to Severe AD Drug Market, by Brand, Spain, (€), 2003-2009

Exhibit 4-27: Moderate to Severe AD Drug Market, by Brand, Japan, (US$), 2003-2009 (Tabular Format)

Exhibit 4-28: Moderate to Severe AD Drug Market, by Brand, Japan, (¥), 2003-2009

Exhibit 4-29: Moderate to Severe AD Drug Market, by Brand, Japan, (US$), 2003-2009 (Graphical Format)

Exhibit 4-30: Leading Competitors in the Moderate to Severe AD Drug Market, by Region, Global, 2004

Exhibit 4-31: Exhibit 4-24: Leading Competitors in the Moderate to Severe AD Drug Market, by Region, Europe, 2004

Exhibit 4-32: Leading Competitors in the Moderate to Severe AD Drug Market, Global, 2004




CHAPTER 5: RESEARCH AND DEVELOPMENT

Exhibit 5-1: Selected New AD Drug Candidates, by Clinical Stage, Q4 2004

Exhibit 5-2: Selected ACh Modulators Drug Candidates, by Clinical Stage, Q4 2004

Exhibit 5-3: Selected Neuroprotective and Neurotrophic Drug Candidates, by Clinical Stage, Q4 2004

Exhibit 5-4: Selected Beta Amyloid Modulators Drug Candidates, by Clinical Stage, Q4 2004

Exhibit 5-5: Selected BACE Inhibitor Drug Candidates, by Clinical Stage, Q4 2004

Abstract

The global AD drug market will continue to experience strong growth over the forecast period driven by increasing AD prevalence, physician and patient awareness, improved diagnostic tools, increasing prices, the introduction of new AD products, and expanded indications for existing products.

Get Full Details About This Report >>
US: 800.298.5699
Int'l: +1.240.747.3093
Buy this Report

Price and Delivery Options

See related reports or call the number above for help from a research specialist.


advertise with us

 

About MarketResearch.com
MarketResearch.com is an online aggregator selling over 160,000 market research reports, company profiles and country profiles from over 600 research firms. Our reports will provide you with the critical business and competitive intelligence you need for strategic planning and marketing research. Coverage includes the US, UK, Europe, Asia and global markets.

 

© MarketResearch.com 2008