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Published by: BCC Research
Published: Dec. 1, 2005 - 188 Pages
Table of Contents
- INTRODUCTION
- GOALS AND OBJECTIVES
- REASONS FOR PUBLISHING THE REPORT
- CONTRIBUTION OF THE REPORT AND FOR WHOM
- SCOPE AND FORMAT OF THE REPORT
- METHODOLOGY
- BCC CREDENTIALS
- DISCLAIMER
- SUMMARY
- Summary Table: U.S. MARKET SIZE AND GROWTH OF ANALYTIC SEPARATION SYSTEMS, THROUGH 2010 ($ MILLIONS)
- Summary Figure: U.S. MARKET SIZE AND GROWTH OF ANALYTIC SEPARATION SYSTEMS, 2002-2010 ($ MILLIONS)
- INDUSTRY OVERVIEW
- TYPES OF ANALYTIC SEPARATIONS SYSTEMS
- BIOSENSORS
- CHROMATOGRAPHY
- ELECTROPHORESIS
- MICROARRAYS
- SPECTROSCOPY
- GOVERNMENT REGULATIONS
- ANALYTICAL SEPARATIONS MARKET BY TECHNOLOGY
- TOTAL MARKET SIZE
- Table 1 U.S. MARKET SIZE AND GROWTH OF ANALYTIC SEPARATION SYSTEMS BY TYPE, THROUGH 2010 ($ MILLIONS)
- Figure 1 SHARE OF U.S. MARKET SIZE FOR ANALYTIC SEPARATIONS SYSTEMS BY TYPE, 2005 AND 2010 (%)
- BIOSENSORS
- DESCRIPTION AND TYPES
- Figure 2 BIOSENSOR SCHEMATIC
- Biocatalysis-Based Biosensors
- Bioaffinity-Based Biosensors
- Microorganism-Based Biosensors
- KEY BIOSENSOR PLAYERS
- Figure 3 BIOSENSOR COMPANY MARKET SHARES, 2004 (%)
- Table 2 BIOSENSOR SUPPLIERS
- U.S. PATENT ANALYSIS
- General Trends
- Table 3 NUMBER OF U.S. PATENTS ISSUED FOR BIOSENSOR TECHNOLOGY ANNUALLY, 1976-2004
- Trends by Country
- Figure 4 SHARES OF U.S. PATENTS AND APPLICATIONS RELATED TO BIOSENSORS BY COUNTRY, 1976-2005 (%)
- Trends by Assignee
- Table 4 U.S. PATENTS ASSIGNED TO KEY PLAYERS IN BIOSENSOR TECHNOLOGY, 1976-2005
- Conclusions of Analysis
- VALUE OF BIOSENSORS FOR ANALYTIC SEPARATIONS
- Table 5 U.S. MARKET SIZE AND GROWTH OF THE ANALYTIC SEPARATION BIOSENSOR MARKET, THROUGH 2010 ($ MILLIONS)
- CHROMATOGRAPHY
- DESCRIPTION AND TYPES
- Liquid Chromatography
- Figure 5 LIQUID CHROMATOGRAPHY SCHEMATIC
- Ion Chromatography
- Gas Chromatography
- Figure 6 GAS CHROMATOGRAPHY SCHEMATIC
- Supercritical Fluid Chromatography
- Figure 7 SUPERCRITICAL FLUID CHROMATOGRAPHY SCHEMATIC
- KEY ANALYTIC CHROMATOGRAPHY PLAYERS
- Figure 8 CHROMATOGRAPHY COMPANY MARKET SHARES, 2004 (%)
- Table 6 CHROMATOGRAPHY SUPPLIERS
- U.S. PATENT ANALYSIS
- Figure 9 U.S. PATENTS AND APPLICATIONS FROM 1976 TO 2005 FOR CHROMATOGRAPHIC TECHNOLOGIES (%)
- General Trends
- Table 7 NUMBER OF U.S. PATENTS ISSUED FOR CHROMATOGRAPHIC TECHNOLOGY ANNUALLY, 1976-2004
- Trends by Country
- Figure 10 SHARES OF U.S. PATENTS AND APPLICATIONS RELATED TO CHROMATOGRAPHY BY COUNTRY, 1976-2005 (%)
- Trends by Assignee
- Table 8 U.S. PATENTS ASSIGNED TO KEY PLAYERS IN CHROMATOGRAPHY TECHNOLOGY, 1976-2005
- Conclusions of Analysis
- VALUE OF CHROMATOGRAPHY FOR ANALYTIC SEPARATIONS
- Table 9 U.S. MARKET SIZE AND GROWTH OF THE ANALYTIC CHROMATOGRAPHY MARKET BY TECHNOLOGY TYPE, THROUGH 2010 ($ MILLIONS)
- ELECTROPHORESIS
- DESCRIPTION AND TYPES
- Gel Electrophoresis
- Figure 11 GEL ELECTROPHORESIS SCHEMATIC
- Two-Dimensional Gel Electrophoresis
- Figure 12 TWO-DIMENSIONAL ELECTROPHORESIS SCHEMATIC
- Polyacrylamide Gel Electrophoresis
- Sodium Dodecyl Sulfate PAGE
- Capillary Electrophoresis
- Figure 13 CAPILLARY ELECTROPHORESIS SCHEMATIC
- Capillary Zone Electrophoresis
- Capillary Gel Electrophoresis
- Capillary Isoelectric Focusing
- Isotachophoresis
- Electrokinetic Chromatography
- Micellar Electrokinetic Capillary Chromatography
- Microemulsion Electrokinetic Chromatography
- Nonaqueous Capillary Electrophoresis
- Capillary Electrochromatography
- KEY ANALYTICAL ELECTROPHORESIS PLAYERS
- Figure 14 ELECTROPHORESIS COMPANY MARKET SHARES, 2004 (%)
- U.S. PATENT ANALYSIS
- Figure 15 U.S. PATENTS GRANTED FROM 1976 TO 2005 FOR ELECTROPHORESIS TECHNOLOGIES (%)
- General Patent Analysis Trends
- Table 10 NUMBER OF U.S. PATENTS AND APPLICATIONS FOR ELECTROPHORESIS TECHNOLOGY ANNUALLY, 1976-2004
- Figure 16 SHARES OF U.S. PATENTS AND APPLICATIONS RELATED TO ELECTROPHORESIS BY COUNTRY, 1976-2004 (%)
- Trends by Assignee
- Table 11 U.S. PATENTS ASSIGNED TO KEY PLAYERS IN ELECTROPHORESIS TECHNOLOGY, 1976-2005
- Conclusions of Analysis
- VALUE OF ELECTROPHORESIS FOR ANALYTIC SEPARATIONS
- Table 12 U.S. MARKET SIZE AND GROWTH OF THE ANALYTIC ELECTROPHORESIS SECTOR BY TECHNOLOGY TYPE, THROUGH 2010 ($ MILLIONS)
- MICROARRAYS
- DESCRIPTION AND TYPES
- DNA Microarrays
- Tissue Microarrays
- Other Types of Microarrays
- Protein Microarrays
- Whole-Cell Microarrays
- KEY MICROARRAY PLAYERS
- Figure 17 MICROARRAY COMPANY MARKET SHARES, 2004 (%)
- U.S. PATENT ANALYSIS
- General Trends
- Table 13 NUMBER OF U.S. PATENTS AND APPLICATIONS FOR BIOSENSOR TECHNOLOGY ANNUALLY, 1995-2004
- Trends by Country
- Trends by Assignee
- Conclusions of Analysis
- VALUE OF MICROARRAYS
- Table 14 U.S. MARKET SIZE AND GROWTH OF THE ANALYTIC SEPARATIONS MICROARRAY SECTOR BY TECHNOLOGY TYPE, THROUGH 2010 ($ MILLIONS)
- SPECTROSCOPY
- DESCRIPTION AND TYPES
- Molecular Spectroscopy
- Infrared Spectroscopy
- Near-Infrared Spectroscopy
- Fourier Transform Infrared Spectroscopy
- Ultraviolet and Visible Spectroscopy
- Electron Spin Resonance Spectroscopy
- Raman Spectroscopy
- Nuclear Magnetic Resonance Spectroscopy
- Ion Mobility Spectrometry
- Figure 18 SCHEMATIC OF THE IONSCAN ION MOBILITY SPECTROMETRY SYSTEM
- Atomic Spectroscopy
- Flame Atomic Absorption Spectroscopy
- Graphite Furnace Atomic Absorption Spectroscopy
- Inductively Coupled Plasma Emission Spectroscopy
- Inductively Coupled Plasma Mass Spectroscopy
- Mass Spectrometry
- Figure 19 MASS SPECTROMETRY SCHEMATIC
- Fluorescence Spectroscopy
- Nondispersive Spectroscopy
- Hyphenated Spectroscopy
- KEY SPECTROSCOPY PLAYERS
- Figure 20 SPECTROSCOPY COMPANY MARKET SHARES, 2004 (%)
- U.S. PATENT ANALYSIS
- Figure 21 U.S. PATENTS AND APPLICATIONS FROM 1976-2005 FOR SPECTROSCOPIC TECHNOLOGIES (%)
- General Trends
- Table 15 NUMBER OF U.S. PATENTS AND APPLICATIONS FOR SPECTROSCOPIC TECHNOLOGY ANNUALLY, 1995-2004
- Trends by Country
- Figure 22 SHARES OF U.S. PATENTS AND APPLICATIONS RELATED TO SPECTROSCOPY BY COUNTRY, 1976-2005 (%)
- Trends by Assignee
- Table 16 U.S. PATENTS ASSIGNED TO KEY PLAYERS IN SPECTROSCOPY TECHNOLOGY, 1976-2005
- Conclusions of Analysis
- VALUE OF SPECTROSCOPY FOR ANALYTIC SEPARATIONS
- Table 17 U.S. MARKET SIZE AND GROWTH OF THE ANALYTIC SPECTROSCOPY SECTOR BY TECHNOLOGY TYPE, THROUGH 2010 ($ MILLIONS)
- VALUE OF ANALYTIC SEPARATIONS BY APPLICATION
- TOTAL MARKET SIZE
- Table 18 U.S. MARKET AND GROWTH OF ANALYTICAL SEPARATIONS SYSTEMS BY APPLICATION, THROUGH 2010 ($ MILLIONS)
- Figure 23 SHARES OF ANALYTICAL SEPARATIONS SYSTEMS BY APPLICATION, 2005 AND 2010 (%)
- BIOSENSORS
- DESCRIPTION AND APPLICATION TYPES
- Defense
- Environment
- Food and Beverage
- Table 19 BIOSENSORS USED BY THE FOOD AND BEVERAGE INDUSTRY
- Medical/Diagnostic Applications
- Glucose Monitors
- Clinical Testing
- Research
- INDUSTRY LEADERS BY APPLICATION
- VALUE OF BIOSENSORS BY APPLICATION
- Table 20 U.S. MARKET FOR ANALYTIC BIOSENSORS BY APPLICATION, THROUGH 2010
- Figure 24 SHARES OF ANALYTIC BIOSENSORS BY APPLICATION, 2005 AND 2010 (%)
- CHROMATOGRAPHY
- DESCRIPTION AND APPLICATION TYPES
- Biotechnology
- Chemical/Petrochemical
- Environmental
- Food and Beverage
- Medical/Pharmaceuticals
- VALUE OF ANALYTICAL CHROMATOGRAPHY BY APPLICATION
- Table 21 U.S. MARKET FOR ANALYTIC CHROMATOGRAPHY BY APPLICATION, THROUGH 2010 ($ MILLIONS)
- Figure 25 SHARES OF ANALYTIC CHROMATOGRAPHY BY APPLICATION, 2005 AND 2010 (%)
- ELECTROPHORESIS
- DESCRIPTION AND APPLICATION TYPES
- Biotechnology
- Genetics
- Proteomics
- Outlook
- Environmental
- Water Monitoring
- Metals Detection
- Environmental Estrogens
- Outlook
- Food and Beverage
- Quality Control
- Dietary Supplements
- Dairy Industry
- Outlook
- Pharmaceuticals
- Drug Analysis
- Drug Development
- Outlook
- VALUE OF ANALYTICAL ELECTROPHORESIS BY APPLICATION
- Table 22 U.S. MARKET FOR ANALYTIC ELECTROPHORESIS BY APPLICATION, THROUGH 2010 ($ MILLIONS)
- Figure 26 SHARES OF ANALYTIC ELECTROPHORESIS BY APPLICATION, 2005 AND 2010 (%)
- MICROARRAYS
- DESCRIPTION AND APPLICATION TYPES
- Biotechnology
- Detection/Diagnosis
- Environmental
- Pharmaceutical
- VALUE OF MICROARRAYS BY APPLICATION
- Table 23 U.S. MARKET FOR ANALYTIC MICROARRAYS BY APPLICATION, THROUGH 2010 ($ MILLIONS)
- Figure 27 SHARES OF ANALYTIC MICROARRAYS BY APPLICATION, 2005 AND 2010 (%)
- SPECTROSCOPY
- DESCRIPTION AND APPLICATION TYPES
- Biotechnology
- Chemical/Industrial
- Environmental
- Food and Beverage
- Pharmaceuticals
- VALUE OF SPECTROSCOPY BY APPLICATIONS
- Table 24 U.S. MARKET FOR ANALYTIC SPECTROSCOPY BY APPLICATION, THROUGH 2010 ($ MILLIONS)
- Figure 28 SHARES OF ANALYTIC SPECTROSCOPY BY APPLICATION, 2005 AND 2010 (%)
- APPENDIX
- COMPANY PROFILES
- ABBOTT LABORATORIES, INC.
- ABTECH SCIENTIFIC, INC.
- ACLARA BIOSCIENCES, INC.
- AFFYMETRIX , INC.
- AGILENT TECHNOLOGIES
- ALCOTT CHROMATOGRAPHY, INC.
- ALLTECH ASSOCIATES, INC.
- AMERSHAM BIOSCIENCES
- AMETEK, INC.
- APPLIED ANALYTICS
- APPLIED BIOSYSTEMS GROUP
- APPLIED SPECTROMETRY ASSOCIATES, INC.
- ATTANA AB
- AVIVA BIOSCIENCES CORP.
- AXIOM ANALYTICAL, INC.
- BAYER DIAGNOSTICS
- BECKMAN COULTER
- BECTON DICKINSON & CO.
- BIACORE INTERNATIONAL, SA
- BIO-RAD LABORATORIES, INC.
- BRINKMANN INSTRUMENTS, INC.
- BRUKER BIOSPIN CORP.
- BRUKER DALTONICS
- CALIPER LIFE SCIENCES, INC.
- CAMBRIDGE LIFE SCIENCES, LTD.
- CELERA DIAGNOSTICS
- CEPHEID THERAPEUTICS
- CIPHERGEN BIOSYSTEMS
- DADE BEHRING, INC.
- DIONEX CORP.
- DUPONT
- ELECTRONIC SENSOR TECHNOLOGY
- ENZO BIOCHEM
- ESA BIOSCIENCES, INC.
- EUROGENTEC
- FLUIDIGM CORP.
- FOSS ANALYTICAL
- FOTODYNE, INC.
- GENE LOGIC
- GENEOHM SCIENCES, INC.
- GENETIX, LTD.
- GENISPHERE, INC.
- HELENA LABORATORIES
- HEWLETT-PACKARD CO.
- HITACHI HIGH-TECHNOLOGIES CORP.
- HOEFER, INC.
- HOME DIAGNOSTICS, INC.
- HORIBA INSTRUMENTS, INC.
- HYPROMATRIX, INC.
- IBIS THERAPEUTICS
- ILLUMINA, INC.
- INTEGRATED SENSING SYSTEMS, INC.
- INVITROGEN LIFE TECHNOLOGIES
- TELEDYNE ISCO
- JASCO, INC.
- JEOL, INC.
- LAB CONNECTIONS, INC.
- LABINTELLIGENCE
- LIFE TECHNOLOGIES, INC.
- LIFESCAN, INC.
- LIFEPOINT, INC.
- LUMINEX CORP.
- M-BIOTECH, INC.
- MEDTRONIC MINIMED
- MERCK BIOSCIENCES
- MICRONICS, INC.
- MILLIPORE, INC.
- MUNICH INNOVATIVE BIOMATERIALS GMBH
- NANOGEN, INC.
- NIMBLEGEN SYSTEMS, INC.
- NOVA BIOMEDICAL
- NUVELO, INC.
- ORCHID BIOSCIENCES, INC.
- PERKINELMER, INC.
- PHENOMENEX
- PHYSICAL ELECTRONICS, INC.
- POWERZYME, INC.
- PROTEOME SCIENCES, PLC
- QIAGEN, INC.
- QUESTSTAR MEDICAL, INC.
- ROCHE DIAGNOSTICS
- ROSEMOUNT ANALYTICAL, INC.
- ROSETTA INPHARMATICS, LLC
- SARTORIUS CORP.
- SAVANT INSTRUMENTS, INC.
- SCANALYTICS, INC.
- SCIENTIFIC INSTRUMENT SERVICES, INC.
- SCHLEICHER & SCHUELL BIOSCIENCE
- SEBIA, INC.
- SELERITY TECHNOLOGIES, INC.
- SEQUENOM, INC.
- SHIMADZU AMERICA/SHIMADZU SCIENTIFIC INSTRUMENTS
- SIGMA-ALDRICH CORP.
- SMITHS DETECTION-PASADENA
- SRI INSTRUMENTS
- STRATEGIC DIAGNOSTICS, INC.
- SUPELCO, INC.
- TELECHEM INTERNATIONAL/ARRAYIT DIVISION
- TELEDYNE ANALYTICAL INSTRUMENTS
- THERMO ELECTRON CORP.
- TOSHIBA CORP.
- VARIAN, INC.
- VYSIS, INC.
- WATERS CORP.
- XANTEC BIOANALYTICS GMBH
- XENOPORE CORP.
- XEOTRON CORP.
- YSI, INC.
- ZYOMYX, INC.
- INDUSTRY ACTIVITY
- BIOSENSORS
- Sontra Presents Clinical Results from Glucose-Monitoring Study
- Bruker Offers Prespotted Anchorchip
- Qtl Biosystems Receives Broad Patent
- Innovative Biosensors Launches Ultrasensitive Test for Pathogenic E. Coli
- Micro-Draw Glucose Monitoring System Receives FDA Approval
- Micro Biosensor Chip Moves Dna
- Isis Pharmaceuticals Gets Award from Department of Homeland Security For Microbial Forensics
- Electronic Nose Sniffs Out Early Traces Of Lung Cancer
- NVE Notified of Biosensor Patent Grant
- CHROMATOGRAPHY
- Agilent Improves PAH Analysis
- CHIRAL DRUGS PRODUCED USING SMB
- Selerity Goes Supercritical
- Varian Offers Diode Array Detector for Broadest Range of HPLC Applications
- UHPLC Possible With Noncapillary Columns
- TPLC ENABLES GREENER SEPARATIONS
- SUPELCO INTRODUCES HPLC COLUMNS USING SURFACE-OPTIMIZED TECHNOLOGY
- Zirchrom to Develop New Class of Chiral Chromatography Products
- Transgenomic Launches Wave Microbial Analysis System
- ELECTROPHORESIS
- Common Cleanser Offers Cheaper DNA Separation
- Combisep Separates with Chromatofocusing
- Brits Attempt To Dry Out DNA Processing
- NextGen Granted a2DE Patent
- CE Microchip Measures Lithium
- Chip Offers Quick Analysis
- Novel Immunoassay Developed
- Researchers Investigate 2D in One Capillary
- Microchip Aids Protein Analysis
- MICROARRAYS
- Purdue Creates Quick Microchips
- Affymetrix Completes Smallpox Array
- Library Printed On a Slide
- NJIT Paves the Way For Cheap Field Tests
- Microchip Tracks Micrornas
- Boston Microsystems Heats Up Lab-On-A-Chip
- Affymetrix Launches Comprehensive Array
- Agilent Achieves Cancer Breakthrough
- SPECTROSCOPY
- Laser Method Counts Toxic Molecules
- MRSI Detects Breast Cancer
- Ion Bright Source Enhances Performance
- Silver Staining Interference Minimized
- ESA Systems Expand Molecular Detection
- Interest in AMS Growing
- Method Speeds Protein Analysis
- A New Spin On NMR
- Flying Through The Vapor Phase
- Laboratory Bloodhound Gets Sharper Nose
- Laser Technique Used In Forensics
- Lawrence Berkeley Observes Ions
- INDUSTRY ACRONYMS
AbstractINTRODUCTION
The field of analytic separations is composed of both established and novel technologies. Both types continue to evolve as limitations are addressed and standards grow even more rigorous. Researchers in university and industrial laboratories continue to explore, develop, and improve processes and technologies. The market is driven primarily by biotech/health care, security, and environmental monitoring. Improvements in quality control, instrument design, and software are having a positive impact on the industry.
Analytic separation is an industry in flux due to the seemingly constant emergence of newly introduced instruments and methods. The industry is comprised of a diverse group of technologies, which are all used to perform some sort of analytic-scale separation; often these technologies may not have much else in common. Used separately or in combination with one another, the analytic separation methods create a multibillion dollar U.S. market.
This report examines techniques used for analytic separations and analyzes the markets by both technology and application. Analytic separations have never been more commonplace; the technologies presented in this report are being used in applications as diverse as air-pollution monitoring and biotechnology. Processing samples in the microscale and nanoscale ranges are the next challenge, with concentrations at the micromole and femtomole level.
SCOPE OF STUDY
The report contains:
- Examination of analytical separation technology categories including biosensors, chromatography, electrophoresis, microarrays and spectroscopy
- A process description for each technique as well as discussion of appropriate uses
- Market analysis, forecasts, and growth rates for the 2005-2010 timeframe by applications and technology
- Examination of the industry’s structure
- Profiles of key organizations involved in the supply of analytic separation systems.
METHODOLOGY
The background research for this report consisted of a thorough analysis of trade, government, and company publications, as well as information contained in Business Communication Co.'s (BCC's) vast database. Interviews with industry representatives, trade associations, and government officials followed the background work. The comments of these people, combined with BCC experience and analysis, provided the basis for the content of this report. The major sources of information are noted throughout the report. The tables reflect forecasts for individual markets and are based on information provided by multiple industry sources, and are followed by reasoned and expert BCC analysis.
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