• Overview of Top Products
  
• Opiate Agonists- Natural Alkaloids
  
• Opiate Agonists-Semisynthetic Analogs
  
• Opiate Agonists- Synthetic Compounds
  
• Phenylpiperdine Compounds
  
• New Products
  
• Market Size and Growth
  
• Market by Region

• Overview of Top Products
  
• Opiate Agonists- Natural Alkaloids
  
• Opiate Agonists-Semisynthetic Analogs
  
• Opiate Agonists- Synthetic Compounds
  
• Opiate Agonist-Antagonists
  
• Centrally-acting Synthetic Analgesic Compounds
  
• New Products
  
• Market Size and Growth
  
• Markets by Region

• Overview of Top Products
  
• Selective Serotonin Agonists
  
• New Products
  
• Market Size and Growth
  
• Markets by Region

• Overview of Top Products
  
• Phenylpiperidine Compounds
  
• Cox-2 Inhibitors
  
• Non-steroid Anti-inflammatory Drugs
  
• Opioid Agonists- Natural Alkaloids
  
• Hyaluronate Sodium Derivative
  
• New Products
  
• Market Size and Growth
  
• Markets by Region

• Overview of Top Products
  
• Antiseizure Drugs
  
• Opiate Agonists- Natural Alkaloids
  
• Opiate Agonists-Semi-Synthetic Analogs
  
• Phenylpiperidine Compounds
  
• New Products
  
• Market Size and Growth
  
• Markets by Region

• Overview of Top Products
  
• Opiate Agonists—Synthetic Compounds
  
• Opiate Agonist—Antagonists
  
• Centrally Acting Synthetic Analgesic Compounds
  
• Market Size and Growth
  
• Markets by Region

• Overview of Top Products
  
• Opiate Agonist-Antagonists
  
• Indole Analogs
  
• Opiate Agonists-Semisynthetic Analogs
  
• Opiate Agonists- Natural Alkaloids
  
• Market Size and Growth
  
• Markets by Region

• Overview of Top Products
  
• Opiate Agonists—Natural Alkaloids
  
• Opiate Agonists—Semisynthetic Analogs
  
• Opiate Agonists—Synthetic Compounds
  
• Opiate Agonist—Antagonists
  
• Centrally Acting Synthetic Analgesic Compounds
  
• New Product Approvals
  
• Market Size and Growth
  
• Markets by Region

Chapter Four: Drug Delivery

• Oral Drug Delivery
  
• Parenteral Drug Delivery
  
• Transdermal
  
• Patient Controlled Analgesia
  
• Intrathecal Implants
  
  
• Electrotransport Drug Delivery
  
• Drug Delivery in Development

Chapter Five: Pain Management Devices

• Transcutaneous Electrical Nerve Stimulators
  
• Neuromuscular Stimulators
  
• Spinal Cord Stimulators and Peripheral Nerve Stimulators
  
• PCAs and Intrathecal Pain Pumps
  
• Other Miscellaneous Devices
  
• Cranial Electrotherapy Stimulation
  
• Electrothermal and Electromagnetic Therapy
  
• Thermography
  
• Market Size and Growth
  
• Markets by Region

Chapter Six: Alternative Treatment Modalities

• Acupuncture
  
• ETPS Neuropathic acupuncture
  
• Low Level Laser Light Therapy
  
• Biofeedback
  
• Relaxation
  
• Music and Pain Relief
  
• Wave Therapy
  
• Acupressure
  
• Massage Therapy
  
• Natural Supplements in Pain Management
  
• Bioelectromagnetism

CHapter Seven: Issues and Trends

• Overview
  
• Barriers to Pain Management
  
• Cancer Pain
  
• Education

• Accelanyl
  
• Arcoxia
  
• Cellegesic
  
• Chronogesic
  
• CIP Tramadol
  
• Hyalgan
  
• Imitrex Nasal Spray (Pediatric)
  
• Pennsaid
  
• Prexige
  
• Trexima
  
• 406381
  
• ALGRX 3268
  
• BEMA-Fentanyl
  
• Bicifadine
  
• Dynastat
  
• HCT 3012
  
• IV APAP
  
• Lacosamide Oral
  
• LidoPain SP
  
• M6G
  
• Memantine (Namenda)
  
• Neurodex
  
• NGX 4010 (Transacin)
  
• OxyTrex
  
• OMS 103 HP
  
• Oros Hydromorphone
  
• Rapinyl
  
• Remoxy
  
• Rylomine
  
• Sativex
  
• Tapentadol
  
• Tavocept
  
• Tramadol
  
• TQ-1017

Chapter Eight: Market Summary

• Total Market Size and Forecast
  
• Top Revenue Producing Products
  
• Competitor Analysis

Chapter Nine: Corporate Profiles

• Abbott Laboratories
  
• AstraZeneca plc.
  
• Baxter International, Inc
  
• Boehringer Ingelheim
  
• Bristol-Myers Squibb Company
  
• Cephalon Inc.
  
• Endo Pharmaceutical Holdings Inc
  
• GlaxoSmithKline plc
  
• Javelin Pharmaceuticals
  
• Johnson & Johnson, Inc
  
• Medtronic, Inc
  
• Merck & Company
  
• Novartis International AG
  
• Ortho-McNeil (J&J)
  
• Pain Therapeutics
  
• Pfizer, Inc
  
  
• Purdue Pharma
  
• Sanofi-Aventis
  
• TEVA Pharmaceutical Industries, Ltd.
  
• Watson Pharmaceuticals, Inc.
  
• Wyeth

Appendix: Company Directory

List of Exhibits

chapter one: Executive Summary

• Table 1-1: Total World Pain Management Market 2004-2010
  
• Table 1-2: World Market for Top Pain Management Treatments Revenues and Segments of Participation by Major Areas of Participation 2006

Chapter Two: Introduction and Overview

• Table 2-1: Most Commonly Used Pain Quality Descriptors
  
• Table 2-2: Pharmacokinetics of Step I Analgesics by Product (Name, Typical
  
• Dose, Approximate Equivalent, Onset Time, Peak Effect Time,
  Duration)
  
• Table 2-3: Pharmacokinetics of Step II Analgesics (Name, Typical Dose, Approximate Equivalent, Onset Time, Peak Effect Time, Duration)
  
• Table 2-4: Pharmacokinetics of Step III Analgesics (Name, Typical Dose, Onset
  
• Time, Peak Effect Time, Duration)
  
• Table 2-5: Prevalence of Selected Pain-Related Conditions (Rheumatoid
  Arthritis, Back Pain, Cancer Pain, Migraine, Neuropathic Pain, Osteoarthritis)

Chapter three: Treatment Markets and Forecasts

• Table 3-1: World Market for Burn Pain Market 2004-2010
  
• Figure 3-1: World Market for Burn Pain Management 2004-2010
  
• Table 3-2: World Market for Burn Pain Management by Geographic Region
  (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 3-2: Regional Markets for Burn Pain Management 2004-2010
  
• Table 3-3: World Market for Cancer Pain Management 2004-2010
  
• Figure 3-3: World Market for Cancer Pain Management 2004-2010
  
• Table 3-4: World Market for Cancer Pain Management by Geographic Region (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 3-4: Regional Markets for Cancer Pain Management 2004-2010
  
• Table 3-5: The World Market for Dental/Facial Pain Management 2004-2010
  
• Figure 3-5: The World Market for Dental/Facial Pain Management 2004-2010
  
• Table 3-6: World Market for Dental/Facial Pain Management by Geographic
  
• Region (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 3-6: Regional Markets for Dental/Facial Pain Management 2004-2010
  
• Table 3-7: World Market for Migraine Pain Management 2004-2010
  
• Figure 3-7: World Market for Migraine Pain Management 2004-2010
  
• Table 3-8: World Market for Migraine Pain Management by Geographic
  
• Region (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 3-8: Regional Markets for Migraine Pain Management 2004-2010
  
• Table 3-9: World Market for Musculoskeletal Pain Management 2004-2010
  
• Figure 3-9: World Market for Musculoskeletal Pain Management 2004-2010
  
• Table 3-10: World Market for Musculoskeletal Pain Management by Geographic Region (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 3-10: Regional Markets for Musculoskeletal Pain Management 2004-2010
  
• Table 3-11: World Market for Neuropathic Pain Management 2004-2010
  
• Figure 3-11: World Market for Neuropathic Pain Management 2004-2010
  
• Table 3-12: World Market for Neuropathic Pain Management by Geographic
  
• Region (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 3-12: Regional Markets for Neuropathic Pain Management 2004-2010
  
• Table 3-13: World Market for Obstetrical Pain Management 2004-2010
  
• Figure 3-13: World Market for Obstetrical Pain Management 2004-2010
  
• Table 3-14: World Market for Obstetrical Pain Management by Geographic
  
• Region (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 3-14: Regional Markets for Obstetrical Pain Management 2004-2010
  
• Table 3-15: World Market for Pediatric Pain Management 2004-2010
  
• Figure 3-15: Total World Pediatric Pain Market 2004-2010
  
• Table 3-16: World Market for Pediatric Pain Management by Geographic
  
• Region (United States, Europe, ROW) 2004-2010
  
• Figure 3-16: Regional Markets for Pediatric Pain Management 2004-2010
  
• Table 3-17: World Market for Surgical and Trauma Pain Management
  2004-2010
  
• Figure 3-17: World Market for Surgical and Trauma Pain Management
  2004-2010
  
• Table 3-18: World Market for Surgical and Trauma Pain Management by Geographic Region (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 3-18: Regional Markets for Surgical and Trauma Pain Management
  2004-2010

chapter five: Pain Management Devices

• Table 5-1: World Market for Pain Management Devices 2004-2010
  
• Figure 5-1: World Market for Pain Management Devices 2004-2010
  
• Table 5-2: World Market for Pain Management Devices by Geographic Region (United States, Europe, Japan, ROW) 2004-2010
  
• Figure 5-2: Regional Markets for Pain Management Devices 2004-2010

Chapter six: Alternative Treatment Modalities

• Table 6-1: Pain Management Supplements in Clinical Trials

Chapter Seven: Issues and Trends

• Table 7-1: Pain Management Products in Development by Phase (Product,
  
• Active Ingredient, Indication, Developer) 2006

chapter eight: Market Summary

• Table 8-1: World Market for Pain Management Drugs and Devices 2004-2010
  
• Figure 8-1: Total World Pain Management Market 2004-2010
  
• Table 8-2: Total World Pain Management Market by Pain Type 2006 vs 2010
  
• Figure 8-2: The World Pain Management Market Share by Pain Type 2006
  
• Figure 8-3: The World Pain Management Market Share by Pain Type 2010
  
• Table 8-3: Revenues and Market Share by Top 16 Revenue-Producing
  Drugs 2006
  
• Figure 8-4: Market Share by Top Revenue Producing Drug 2006
  
• Table 8-4: World Market for Top Pain Management Treatments Revenues and Segments of Participation by Major Areas of Participation 2006

Abstract

Since more than 11 million Americans report pain as a significant disability, there’s no question that pain management is big business for healthcare practitioners today, and one area that market watchers need to understand. When viewed globally, there is a large underserved population for pain management medications, which indicates growth in what is now a 26 billion-dollar plus industry.

How big will the pain management drug and device market get in the next four years? Who are the key players that will lead this growth? What are the fastest-growing segments of pain management and which segments will just keep pace or fall? How will the Vioxx recall and Tylenol’s association with liver damage affect pain management market as a whole? What new drugs are in the pipeline and how are they expected to change the competitive landscape?

Kalorama’s World Market for Pain Management Drugs and Devices is your guide to the pain management marketplace. In great detail, the report analyzes the global marketplace for pain management products currently available and those in the product pipeline. Segmenting the market by pain indication, the report provides size, growth, and forecasts to 2010 for nine major pain indications:

• Burn Pain
• Cancer Pain
• Dental/Facial Pain
• Migraine Headache Pain
• MusculoSkeletal Pain
• Neuropathic Pain
• Obstetrical Pain
• Pediatric Pain
• Surgical and Trauma Pain

The truly global perspective of this report takes this information one step further, breaking down each of those segments by geography, providing current revenues and forecast revenues to 2010 by region:

• United States
• Europe
• Japan
• Rest of World

A comprehensive survey, Kalorama’s World Market for Pain Management Drugs and Devices provides information and market data on the pain management medical device sector as well, including modality/product descriptions, revenue forecasts, and regional breakdowns through 2010.

Competitive information on pipeline and product offerings as well as market share by top drug are provided. Extensive discussions of issues and trends, including chapters devoted to drug delivery and alternative pain therapies, and profiles of selected companies round out the comprehensive look at the market.

Kalorama’s trusted information-gathering process relies on more than just research into company and government data. Over 51 industry executives were interviewed to provide the basis for the market data and forecasts made in this report. The information and analysis presented in this report are based on extensive interviews with senior management of top companies and conference participants (business and clinical) in the pain management market. Background information was obtained from a comprehensive search of published literature and reports obtained from various government, business, medical trade, and international journals. Interviews were also used to confirm and/or adjust market size estimates, as well as in formulating market projections.