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Knowledge Management Tools for Drug Discovery

Published by: Decision Resources

Published: Jun. 15, 2005 - 19 Pages


Table of Contents


Overview

The Challenge: Integrating Information and Knowledge

Challenges in Knowledge Generation

Electronic Laboratory Notebooks

Model-Oriented Knowledgebases

Evolution Toward Integrated Applications

Company Profiles

Outlook for Electronic Laboratory Notebooks and Knowledgebases




Table 1. Electronic Laboratory Notebook Vendors and Organizations

Table 2. Model-Oriented Knowledgebase Vendors and Organizations




Figure 1. Silos of Expertise

Figure 2. The Scientific Method Workflow

Figure 3. Synthesizing Knowledge to Make Decisions

Abstract

Pharmaceutical companies are investing in new R&D technologies in the hope that they will accelerate research and, ultimately, improve both productivity and profitability. Before these technologies can boost profitability, however, the data they produce must be converted into knowledge that can be applied to the development of new drugs. A significant bottleneck in this process is the long practiced, but inefficient, method that scientists use to integrate new data and information with existing knowledge-i.e., the paper-based notebook. In this report, we examine how knowledge management principles can be used to identify and apply computational tools, including electronic laboratory notebooks and knowledgebases, to synthesize scientific knowledge.

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