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Prevention of Coronary Heart Disease - Promoting Healthy Lifestyles

Published by: Datamonitor

Published: Jul. 29, 2005 - 39 Pages


Table of Contents


TABLE OF CONTENTS

EXECUTIVE SUMMARY 4

Introduction 4

Scope and coverage of the Brief 4

Key findings 4

ATHEROSCLEROSIS OVERVIEW 6

Disease definition 6

Epidemiology 7

Burden of atherosclerosis and coronary heart disease 8

PREVENTION OF ATHEROSCLEROSIS 11

Atherosclerotic risk factors 11

AHA recommendations for the prevention of coronary heart disease 17

Therapeutic lifestyle changes 24

Drug therapy 24

Metabolic syndrome 28

APPENDIX 36

Bibliography 36





Abstract

Introduction
Coronary heart disease is the most common cause of death in Europe and the US, at a rate of one in five. However, the majority of coronary events can be prevented by education about risk factors, lifestyle changes and drug therapy. The increasing prevalence of metabolic syndrome, which is a cluster of risk factors in one individual, is associated with a two-fold increase in cardiovascular disease.

Scope
Examines atherosclerosis epidemiology, mortality statistics and the burden it places on healthcare spending
Identifies the risk factors which can be changed or treated to reduce the risk of atherosclerotic disease
Explores risk factor screening, global risk estimation and risk intervention measures including therapeutic lifestyle changes and drug therapy
Recognizes the significance of multiple risk factors present in one individual as metabolic syndrome, leading to coronary heart disease
Highlights
Cardiovascular disease is the leading cause of mortality in the US and Europe with more than one in five deaths from coronary heart disease. Also, the cost of coronary heart disease is huge -the American Heart Association estimates costs of $142 billion in 2005 and the British Heart Foundation estimates it costs the UK almost $14 billion per year.

The majority of heart disease is potentially preventable through continued education and identification of risk factors to prevent the onset of cardiovascular disease leading to heart attack or stroke. Guidelines promote a healthy diet, weight loss and exercise, although drug therapy is recommended where lifestyle changes are insufficient.

Metabolic syndrome is characterized by a cluster of risk factors in one individual. Central obesity and insulin resistance are considered important causative factors. This combination leads to a high risk of type 2 diabetes and cardiovascular disease with an increase in risk of between 1.5 and 2 times.

Reasons to Purchase
Examine the epidemiology of coronary heart disease to identify future patient potential and new market opportunities
Align your product portfolio to the key risk factors associated with coronary heart disease and target the most lucrative markets
Explore current treatment practices and the extent to which unmet needs are not met in order to target additional gaps in the market



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