Life Science Informatics: Strategies & Business Models

Published by: Datacomm Research

Published: May. 1, 2003 - 143 Pages

Table of Contents

Executive Summary

The current market

Opportunities & illusions

Business models & strategies

Conclusions & recommendations

Mapping the Genome and Searching for Profits

Life Science Informatics

Applications

Research

Health care

Pharmaceuticals

Agriculture

Veterinary

Food processing

Forensics

Manufacturing

IT applications

Information technology (IT) infrastructure

Data access

Data storage

Computing architectures

The Market

Pharmaceutical and biotech firms

Government and university research labs

Healthcare providers

Information Technology Opportunities & Requirements

Regulatory Issues

Business models

Focus: Hardware

Computing hardware sales

Storage hardware sales

Networking hardware sales

Instrumentation hardware sales

Focus: Life Science Informatics Services

Application Service Provider (ASP)

Outsourced Drug Discovery Processes

Consulting

Focus: Software

Discipline-based tools

Task-based tools

Software: off-the-shelf

Software: customized for flat fee

Software licensing: free with charges for upgrades, support, and extras

Software licensing: modest upfront fee plus royalties

Software licenses: upfront fee plus annual maintenance and consulting

Focus: Systems & Other

Integration model

Eclectic model

Strategic collaboration/acquisition model

Drug discovery model

Healthcare applications model

Vendor Profiles

3rd MILLENIUM INC.

ACCELRYS

ACLARA

AFFYMETRIX

AGILENT TECHNOLOGIES

ALGONOMICS

ALKAMI BIOSYSTEMS

ANVIL

ARQULE

APPLIED BIOSYSTEMS GROUP

BIODISCOVERY

BIOINFORMATICS SOLUTIONS

BIOSENTIENTS

BIOTOOLS INC.

BLACKSTONE COMPUTING

CALLIDA GENOMICS

CB TECHNOLOGIES

CELERA GENOMICS

CEREP

COMPUGEN

CURAGEN

DECODE GENETICS

DECODON

DELTAGEN, INC.

DISCOVERY PARTNERS INTERNATIONAL

ENTELOS INC.

GENEDATA

GENEFORMATICS, INC.

GENEPROT

GENE LOGIC

GENODYSSEE

GENOME THERAPEUTICS CORP.

GENOMICS COLLABORATIVE

GENOMIC SOLUTIONS

GEOSPIZA

HEWLETT-PACKARD

IBM LIFE SCIENCES

IMAGING RESEARCH

INCYTE GENOMICS, INC.

INFORMAX

KSHEMA TECHNOLOGIES

LABSTREAM

LARGE SCALE BIOLOGY CORP.

LINUX NETWORX

LION BIOSCIENCE

MOLECULAR MINING

MOTOROLA LIFE SCIENCES

NANOGEN

NEXUS GENOMICS

PANVERA LLC

PARACEL

PARTEK

PERLEGEN SCIENCES

PHARSIGHT

PHASE FORWARD

PHT CORPORATION

PHYSIOME SCIENCES

PLATFORM COMPUTING

ROSETTA INPHARMICS

SILCON GENETICS

SPOTFIRE

STRAND GENOMICS PVT. LTD.

STRUCTURAL BIOINFORMATICS INC.

STRUCTURAL GENOMICS

THIRD WAVE TECHNOLOGIES

TIMELOGIC

TISSUEINFORMATICS

TRIPOS

TURBOWORX

UNITED DEVICES

VISUALIZE INC.

Tables

Table 1 Factors Driving/Inhibiting Life Science Informatics Business

Table 2 Major life science informatics activities

Table 3 Major supercomputer manufacturers

Table 4 Twenty largest supercomputing sites

Table 5 Comparison of supercomputers, server clusters, and grid computing

Table 6 Major manufacturers of server clusters

Table 7 Comparison of high speed network interfaces

Table 8 The largest pharmaceutical and biotech firms

Table 9 Buyer profiles for four major life science informatics market segments

Table 10 Growth in GenBank database, 1982 - 2002

Table 11 Advantages & disadvantages (for customers) of using application service providers (ASPs)

Table 12 Business model evolution for select life science informatics vendors

Figures

Figure 1 Major high performance computing architectures (supercomputer, server cluster, and grid)

Figure 2 Percentage of top 500 high performance computing sites dedicated to life sciences

Figure 3 Blade server architecture saves space and reduces power consumption

Figure 4 Growth in European Molecular Biology Laboratory (EMBL) database, 1982 - 2003

Figure 5 New drug applications, 1995 – 2003 (first part of 2003)

Figure 6 Drug development & approval process

Figure 7 Breakdown of drug development costs, US$ millions

Abstract

Life science informatics promises to harness the flood of data from the Human Genome Project and related research. But living organisms are complex, and designing drugs exclusively in silico is not ready for prime time. Based on months of research, this report sheds new light on the life science informatics industry: what's real, what's not, and how today's science-driven ventures can become tomorrow's profit makers.

Life Science Informatics: Strategies & Business Models is the latest in Datacomm Research's CompetitiveEdge™ series. The report is based on more than two dozen in-depth interviews and includes sections on life science informatics applications and markets, information technology infrastructure (including storage area networks, server clusters, and grid computing), and business models. More than 70 vendors-from 3rd Millenium, Inc. to Visualize, Inc.-are profiled.

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