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Indian Bioinformatics industryPublished by: Digital Vector Published: Oct. 1, 2004 - 45 Pages Table of ContentsINTRODUCTION BIOTECHNOLOGY DEFINED TISSUE CULTURE CELL FUSION EMBRYO TRANSFER RECOMBINANT DNA TECHNOLOGY APPLICATIONS OF BIOTECHNOLOGY HEALTHCARE AGRICULTURAL BIOTECHNOLOGY THE HUMAN GENOME PROJECT (HGP) GOALS OF THE HUMAN GENOME PROJECT BENEFITS OF THE HUMAN GENOME PROJECT GENOMICS ROLE OF IT DATA MANAGEMENT EXPERIMENTATION, SIMULATION AND INFORMATION RESEARCH EFFICIENCY INFORMATICS DEFINITION & ROLE OF BIOINFORMATICS TYPES OF DATA AND BIOINFORMATICS APPLICATIONS HISTORICAL PERSPECTIVE CURRENT STATE FUNCTIONS OF INFORMATICS SOFTWARE INDUSTRY CHARACTERISTICS TARGET MARKETS FOR INFORMATICS SOFTWARE STEPS INVOLVED IN BRINGING A DRUG TO MARKET COSTS INCURRED IN DEVELOPING A NEW DRUG INDUSTRY DRIVERS AND CHALLENGES INDUSTRY RISKS PRODUCTS, PROCESSES & TOOLS OF BIOINFORMATICS PRODUCTS OF BIOINFORMATICS BIOINFORMATICS PROCESSES INFORMATICS TOOLS AND FUNCTIONALITIES ROLE OF BIOINFORMATICS IN THE BIOTECHNOLOGY VALUE CHAIN BIOINFORMATICS MARKET SEGMENTS DATABASE HARDWARE SOFTWARE BIOINFORMATICS SERVICES BIOINFORMATICS MARKET SIZE METHODOLOGY SALES AND R&D IT BUDGET PROJECTED BIOINFORMATICS MARKET SIZE BIOINFORMATICS MARKET BREAK-UP BIOINFORMATICS BUSINESS MODELS CHANGING BUSINESS MODELS COMPETITION FOR PURE PLAY INFORMATICS FIRMS NONPROFIT ORGANIZATIONS IN-HOUSE BIOINFORMATICS SOLUTIONS LARGE IT COMPANIES BIOINFORMATICS TARGET SCIENTIFIC DISCIPLINES COMPARATIVE GENOMICS PHARMACOGENOMICS FUNCTIONAL GENOMICS PROTEOMICS STRUCTURAL GENOMICS IMAGE INFORMATICS CLINICAL TRIAL INFORMATICS BIOINFORMATICS ARCHITECTURE BIOINFORMATICS APPLICATIONS DATA SEARCH TOOLS DATA VISUALIZATION TOOLS DATA MINING AND CLUSTERING APPLICATIONS ENTERPRISE SOLUTIONS DATAWAREHOUSING EVALUATION OF BIOINFORMATIC SOLUTIONS REQUIREMENTS STUDY SHORTLISTING THE OPTIONS SCORING PATTERNS PERFORMANCE DATA STORAGE DATA MANAGEMENT IN DRUG DISCOVERY KEY ISSUES IN BIOINFORMATICS STORAGE CONVERGENCE OF INDUSTRIES PROTEINS AS A DRIVER BIOTECH ALLIANCES CURRENT BIOINFORMATICS RESEARCH PATENTING BIOINFORMATICS ALGORITHMS CURRENT STATE OF THE INDUSTRY THE FUTURE TRENDS FOR THE FUTURE KEY APPLICATIONS OF THE FUTURE List of Tables Table 1: Leading Biotechnology companies Table 2: Data source and Bioinformatic Investigations Table 3: Drivers and challenges of the Bioinformatics industry Table 4: Bioinformatics courses on offer Table 5: Web based Bioinformatics courses on offer Table 6 - Bioinformatics activities, sub activities and key players Table 7: Alliances between IT/Telecom and Biotechnology firms List of Figures Figure 2: Number of Venture Capital deals in biotechnology Figure 3: Equity investments in biotechnology during year 2001 Figure 4: Informatics applications along the drug discovery value chain Figure 5: Bioinformatics software functionalities Figure 6: Growth of GenBank Figure 7: EMBL Database Growth Figure 8: Steps involved in bringing a drug to market Figure 9: Break up of the total costs in developing a new drug ($ US Million) Figure 10: Role of Bioinformatics in the biotechnology value chain Figure 11: Worldwide projected sales and R&D Expenditure ($ US Billion) Figure 12: Worldwide projected growth in IT Budget ($ US Billion) Figure 13: Worldwide projected Bioinformatics market ($ US Billion) Figure 14: Worldwide Bioinformatics market break-up ($ US Billion) Figure 15: Steps of a Proteomics experiment Figure 16: Bioinformatics Architecture Vendor Profiles 1. 3RD MILLENIUM INC. (WWW.3RDMIL.COM) 2. ACCELRYS (WWW.ACCELRYS.COM) 3. ACLARA (WWW.ACLARA.COM) 4. AGILENT TECHNOLOGIES (WWW.AGILENT.COM) 5. ALGONOMICS (WWW.ALGONOMICS.COM) 6. AFFYMETRIX (WWW.AFFYMETRIX.COM) 7. ALKAMI BIOSYSTEMS (WWW.ALKAMI.COM) 8. ANVIL (WWW.ANVILINFORMATICS.COM) 9. BIODISCOVERY (WWW.BIODISCOVERY.COM) 10. BIOINFORMATICS SOLUTIONS (WWW.BIOINFORMATICSSOLUTIONS.COM) 11. BIOSENTIENTS (WWW.BIOSENTIENTS.COM) 12. BIOTOOLS INC. (WWW.BIOTOOLS.COM) 13. BLACKSTONE COMPUTING (WWW.BLACKSTONECOMPUTING.COM) 14. CELERA (WWW.CELERA.COM) 15. COMPUGEN (WWW.CGEN.COM) 16. CURAGEN (WWW.CURAGEN.COM) 17. DECODON (WWW.DECODON.COM) 18. DISCOVERY PARTNERS INTERNATIONAL (WWW.DISCOVERYPARTNERS.COM) 19. GENEDATA (WWW.GENEDATA.COM) 20. GENE LOGIC (WWW.GENELOGIC.COM) 21. GENODYSSEE (WWW.GENODYSSE.COM) 22. GENOMICS COLLABORATIVE (WWW.GENOMICSINC.COM) 23. GENOMIC SOLUTIONS (WWW.GENOMICSOLUTIONS.COM) 24. GEOSPIZA (WWW.GEOSPIZA.COM) 25. IMAGING RESEARCH (WWW.IMAGINGRESEARCH.COM) 26. INCYTE (WWW.INCYTE.COM) 27. INFORMAX (WWW.INFORMAXINC.COM) 28. KSHEMA TECHNOLOGIES (WWW.KSHEMA.COM) 29. LABSTREAM (WWW.LABSTREAM.COM) 30. LION BIOSCIENCE (WWW.LIONBIOSCIENCE.COM) 31. MOLECULAR MINING (WWW.MOLECULARMINING.COM) 32. NEXUS GENOMICS (WWW.NEXUSGENOMICS.COM) 33. PARACEL (WWW.PARACEL.COM) 34. PARTEK (WWW.PARTEK.COM) 35. ROSETTA INPHARMICS (WWW.RII.COM) 36. SILCON GENETICS (WWW.SILICONGENETICS.COM) 37. SPOTFIRE (WWW.SPOTFIRE.COM) 38. STRAND GENOMICS PVT. LTD. (WWW.STRANDGENOMICS.COM) 39. STRUCTURAL BIOINFORMATICS INC. (WWW.STRUBIX.COM) 40. THIRD WAVE TECHNOLOGIES (WWW.TWT.COM) 41. TIMELOGIC (WWW.TIMELOGIC.COM) 42. TRIPOS (WWW.TRIPOS.COM) 43. TURBOGENOMICS (WWW.TURBOGENOMICS.COM) AbstractThe industry comprises of players in areas such as contract research and development (R and D) services, clinical and proof of concept clinical investigation, clinical trials, contract research, bio-engineering, stem cell research, contract manufacturing, bioinformatics and drug development. We are also witnessing activity in the field of research and development in biotechnology with companies like Ranbaxy, Dr Reddy’s Laboratories and Nicholas Piramal have been working on licensed molecules, clinical trials of drugs already formulated, and bioprospecting from Ayurveda, which is India’ s traditional medicine.
The Indian software companies have
come up with the software tools to
capture, manage and analyse the
voluminous amount of genetic data.
India’ s skilled but low cost manpower is
the reason why MNCs are sending their
genomic and proteomic data to India for
analysis. A key advantage of India is the
availability of skilled but low cost
manpower. Unlike IT, bioinformatics
requires a highly skilled work force with
knowledge of IT, molecular biology,
protein separation chemistry, instrument
control, data acquisition and data
analysis tools. |
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