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Commercial Insight: Asthma and COPD - Control is the Goal

Published by: Datamonitor

Published: Oct. 21, 2004 - 90 Pages


Table of Contents


TABLE OF CONTENTS

CHAPTER 1 EXECUTIVE SUMMARY 3

Objective of the analysis 3

Datamonitor insight into the disease market 3

CHAPTER 2 MARKET DEFINITION AND OVERVIEW 8

Market definition for this report 8

Current market situation 9

Strategic scoping and focus 15

CHAPTER 3 COUNTRY MARKET ASSESSMENTS 16

Current and future opportunities and threats in the asthma/COPD market 16

Global opportunities and threats 16

Opportunities 16

Threats 19

US: opportunities and threats 24

Opportunities 24

Threats 25

Japan: opportunities and threats 27

Opportunities 27

Threats 28

France: opportunities and threats 31

Opportunities 31

Threats 32

Germany: opportunities and threats 32

Opportunities 32

Threats 33

Italy: opportunities and threats 34

Opportunities 34

Threats 34

Spain: opportunities and threats 36

Opportunities 36

Threats 36

UK: opportunities and threats 37

Opportunities 37

Threats 39

CHAPTER 4 FORECAST ANALYSIS 42

Assumptions and events 42

Combination class 43

Oral anti-inflammatories class 54

Long & short B2-agonist class 55

Anti-muscarinic class 57

Biological class 58

Limitations of data 59

Forecasts 60

CHAPTER 5 COMMERCIAL IMPACT AND LIFECYCLE MANAGEMENT: CASE STUDIES 61

Introduction 61

Case studies 61

Advair - redefining the approach to asthma management 61

Sepracor - building a primary care presence 65

APPENDIX A - MARKET DATA AND MAJOR BRAND KEY FACTS 70

Global disease market data 70

Combination ICS/LABA 71

Oral non-steroidal anti-inflammatories 73

Inhaled corticosteroids 74

Long-acting bronchodilators 76

Long-acting anti-cholinergics 78

Combination anticholinergic/short-acting b2 agonists 79

Short-acting anticholinergics 80

APPENDIX B 81

Bibliography 81

Glossary 86

Report methodology 87

About Datamonitor 88

About Datamonitor Healthcare 88

About the Respiratory & Infectious Diseases analysis team 89

Disclaimer 90





Abstract

Introduction
The world market for asthma/COPD drugs, valued at $13.3 billion in 2003, is forecast to grow to $19.0 billion by 2009, driven by the expansion of combination steroid/bronchodilator products into a wider spectrum of patients, and strong growth in COPD specific therapies. GlaxoSmithKline and Merck remain the indisputable leaders in asthma, with Pfizer steadily building a presence in COPD.

Scope
Outlook for the asthma/COPD market, including key events impacting combination products, leukotriene antagonists, and anticholinergics
Global sales forecasts to 2014, including country-specific forecasts for the US, Japan, France, Germany, Italy, Spain and the UK
Review of global and country specific opportunities and threats impacting key brands, including Seretide, Symbicort, Singulair, Spiriva, and Daxas
Case studies on Seretide's promotional strategies on redefining asthma management, and building Xopenex's primary care presence
Highlights
GSK has added fresh impetus to Seretide growth by focusing on the control of asthma, rather than symptom severity, enabling Seretide to appeal to the full spectrum of patients and move beyond moderate to severe asthma.

The growth of Spiriva and Daxas will add breadth to an underdeveloped market and establish Pfizer as the premier company in COPD, which is the fastest growing segment of the market. Landmark morbidity and mortality trials, improved awareness, diagnosis and earlier therapeutic intervention, indicates a very promising outlook for this disease.

The dominance of Seretide and Singulair is not likely to be challenged in the foreseeable future, although the large market size, with few NCEs, makes it possible for companies to successfully launch niche products through effective patient targeting.

Reasons to Purchase
Evaluate the expansion of combination products into a wider spectrum of patients through new indications and promotional activities
Quantify the future size and scope of the asthma/COPD market and predict the future performance of key compounds
Examine the impact of future patent expiries in each of the seven country markets



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