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Commercial Insight: Antihypertensives - Can Manufacturers Maintain Value?Published by: Datamonitor Published: Oct. 22, 2004 - 89 Pages Table of ContentsTABLE OF CONTENTS CHAPTER 1 EXECUTIVE SUMMARY 3 Objective of the analysis 3 Datamonitor insight into the hypertension market 4 CHAPTER 2 CURRENT MARKET ASSESSMENTS 9 Strategic scoping and focus 9 Market definition for this report 10 Antihypertensive drug classes 11 Global overview 19 Global: current market assessment 20 National markets 26 Leading global brands 27 Market issues 28 US: current market assessment 41 Overview 41 Market issues in the US 42 Japan: current market assessment 45 Overview 45 Market issues in Japan 46 European Union: current market assessment 48 Overview 48 Market issues in the EU5 49 Summary of environmental issues affecting antihypertensive market size 55 CHAPTER 3 FORECAST ANALYSIS 56 Assumptions and events 56 Ongoing trends 56 Trial results 56 New product launches 59 Patent expiries 60 ARB patent expiries 61 CCB patent expiries 63 Beta-blocker patent expiries 63 ACE inhibitor patent expiries 64 Other patent expiries 65 Additional indications 65 Methodology 67 Forecasts 67 CHAPTER 4 COMMERCIAL IMPACT AND LIFECYCLE MANAGEMENT: CASE STUDIES 68 Introduction 68 Clinical trials 69 Gaining novel additional indications 73 Entry strategy 76 APPENDIX A - MARKET DATA AND MAJOR BRAND KEY FACTS 80 Global hypertension market data 80 Therapeutic classification 80 APPENDIX B 83 Bibliography 83 Report methodology 85 General 85 Japan sales data 85 ATC codes 85 Key opinion leaders 85 About Datamonitor 86 About Datamonitor Healthcare 86 About the Cardiovascular Disease analysis team 87 Disclaimer 88 Glossary 89 AbstractIntroductionThe antihypertensive market accounted for almost $30 billion in the seven major markets in 2003 and this value is set to rise as prevalence increases. The increasing use of multiple drug therapy and the falling use of older drug classes in the absence of specific compelling indications is continuing to drive sales of the largest classes and will provide a growing market for an new entrants. Scope Country specific event-driven sales forecasts for the period 2004-14 for the US, Japan, France, Germany, Italy, Spain and the UK and Global overview Patient potential and prescribing trends overview of the antihypertensive market based on historical sales data and future key events Profiles of the country and market specific issues which will impact future sales in the market including generic erosion and class switching Case studies presenting the effect of launch strategy into the ARB market, additional indications and outcome-based clinical trials Highlights The antihypertensive market has seen continuing growth driven by increasing global prevalence and more aggressive treatment allow it to grow to a 30 billion dollar market in 2003, these trends are set to continue but as governments seek to reduce healthcare spending antihypertensives will come under scrutiny as a source of savings. Patent expiries of major brands will be the leading events shaping the future of the antihypertensives market in the period until 2014, the global market leader, Norvasc, and the fastest growing class, ARBs, will both face genericization during this period, driving down costs and encouraging switching from older classes. Datamonitor forecasts that combination products will drive sales in the ARB class once key product patent expiries force allow genericization of plain formulation products, however physicians are often cynical of manufacturers motives for producing these combinations and the benefits to patients must be highlighted to maintain physician confidence. Reasons to Purchase Identify possible future strategy to maximize product potential and minimize risks for the ARB market View independent, event-driven forecasts for key antihypertensive products and classes across the seven major markets Assess the impact of the Norvasc patent expiry on the market and identify which CCBs, if any, could benefit from the increased competition Get Full Details About This Report >> |
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