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Worldwide Markets for Blood Disorder Treatments

Published by: BCC Research

Published: Jun. 1, 2004 - 142 Pages


Table of Contents


Introduction

Study Goals And Objectives



Scope Of Study



Methodology And Information Sources



Analyst Credentials



Related Bcc Reports



Bcc Online Services



Disclaimer


Executive Summary

Summary Table:

Worldwide Market Size Of Blood Disorder Treatments By Revenues At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Summary Figure:

Worldwide Market Size Of Blood Disorder Treatments By Revenues At Manufacturers' Sales Levels, 2001-2008 ($ Millions)


Industry Overview

Structure And Function Of The Hematological System



Bone Marrow



Blood Cells



Red Blood Cells



White Blood Cells



Platelets



Spleen



Lymph System



Liver



Normal Clotting Mechanisms



Effects Of Aging On The Hematologic System



Blood-Related Medical Conditions



Anemia



Table 1 Common Causes Of Anemia



Anemia Caused By Decreased Erythrocyte Production



Iron Deficiency Anemia



Thalassemia



Megaloblastic Anemia



Vitamin B12 Deficiency



Anemia Of Chronic Disease



Aplastic Anemia



Anemia Caused By Blood Loss



Anemia Caused By Increased Erythrocyte Destruction



Sickle Cell Disease



Glucose-6-Phosphate Dehydrogenase Deficiency



Acquired Hemolytic Anemia



Polycythemia



Table 2 Types Of Anemia



Hemophilia



Table 3 Common Causes Of Hemophilia



Neutropenia



Table 4 Common Infectious Causes Of Neutropenia



Table 5 Common Medication Causes Of Anemia



Thrombocytopenia



Table 6 Common Causes Of Thrombocytopenia



Thrombosis



Thromboembolus



Deep Vein Thrombosis



Table 7 Common Causes Of Thrombosis



Demographics



Table 8 Estimated U.S. Cases Of Selected Chronic Conditions/Diseases Treated With Blood Treatments, 2003



Figure 1 Estimated U.S. Cases Of Selected Leading Chronic Conditions/Diseases Treated With Blood Treatments, 2003



Table 9 Estimated Worldwide Cases Of Selected Chronic Conditions/Diseases Treated With Blood Treatments, 2003



Figure 2 Estimated Worldwide Cases Of Selected Leading Chronic Conditions/Diseases Treated With Blood Treatments, 2003



Table 10 U.S. Population By Selected Age Groups And By Percent Of Total Population, Through 2008 (Millions)



Figure 3 U.S. Population By Selected Age Groups, 2002-2008 (Millions)



Table 11 Worldwide Population By Selected Age Groups And By Percent Of Total Population, Through 2008 (Millions)



Figure 4 Worldwide Population By Selected Age Groups, 2002, 2003 And 2008 (Millions)



Licensing Disputes



Amgen And Ortho Biotech



Epogen



Procrit



Amgen And Transkaryotic Technologies



Education/Resources



Telemedicine For Hemophilia



Education



Reimbursement Issues



Cost



Pharmaceutical Landscape Changes



Impact Of Biotechnology



Table 12 Marketed Biotechnology Blood Treatments



Table 13 Marketed Biotechnology Product Impact



Biotechnology Products On The Market For Blood Disorders



Recombinant Human Erythropoietin



Leukine



Neupogen



Reopro



Retavase



Activase



Integrilin



Angiomax



Tnkase



Computers, Lifestyle, And Dvt



Medicare And The Elderly



Airline Travel Issues



Solutions To Airline-Caused Dvt



Pharmaceutical Rebate Issues



Rebate System Complexity



Product Segments By Type



Anemia Treatments



Anabolic Steroids



Cyanocobalamin And Combinations



Erythropoiesis Stimulants



Folic Acid And Derivatives



Iron And Derivatives



Hemophilia Treatments



Antihemophilic Factor



Anti-Inhibitor Coagulant Complex



Factor Ix Complex



Neutropenia Treatments



Granulocyte Colony Stimulating Factor



Granulocyte Macrophage Colony Stimulating Factor



Thrombosis Treatments



Anticoagulants



Antiplatelet Agents



Antithrombin Iii Agents



Thrombin Inhibitors



Thrombolytic Agents


Market Size And Growth

Table 14 Worldwide Market Size Of Blood Disorder Treatments By Revenues At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 5 Worldwide Market Size Of Blood Disorder Treatments By Revenues At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Blood Disorder Treatment Market By Geography



Table 15 Geographical Distribution Of Revenues In The Worldwide Blood Disorder Treatments Market At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 6 Geographical Distribution Of Revenues In The Worldwide Blood Disorder Treatments Market At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Blood Disorder Treatment Markets By Segment



Anemia Treatments Market



Table 16 Worldwide Market Size Of Anemia Treatments By Revenues At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 7 Worldwide Market Size Of Anemia Treatments By Revenues At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Table 17 Geographical Distribution Of Revenues In The Worldwide Anemia Treatments Market At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 8 Geographical Distribution Of Revenues In The Worldwide Anemia Treatments Market At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Hemophilia Treatments Market



Table 18 Worldwide Market Size Of Hemophilia Treatments By Revenues At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 9 Worldwide Market Size Of Hemophilia Treatments By Revenues At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Table 19 Geographical Distribution Of Revenues In The Worldwide Hemophilia Treatments Market At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 10 Geographical Distribution Of Revenues In The Worldwide Hemophilia Treatments Market At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Neutropenia Treatments Market



Table 20 Worldwide Market Size Of Neutropenia Treatments By Revenues At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 11 Worldwide Market Size Of Neutropenia Treatments By Revenues At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Table 21 Geographical Distribution Of Revenues In The Worldwide Neutropenia Treatments Market At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 12 Geographical Distribution Of Revenues In The Worldwide Neutropenia Treatments Market At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Thrombosis Treatments



Table 22 Worldwide Market Size Of Thrombosis Treatments By Revenues At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 13 Worldwide Market Size Of Thrombosis Treatments By Revenues At Manufacturers' Sales Levels, 2001-2008 ($ Millions)



Table 23 Geographical Distribution Of Revenues In The Worldwide Thrombosis Treatments Market At Manufacturers' Sales Levels, Through 2008 ($ Millions)



Figure 14 Geographical Distribution Of Revenues In The Worldwide Thrombosis Treatments Market At Manufacturers' Sales Levels, 2001-2003 And 2008 ($ Millions)


Research And Development

Table 24 Selected Blood Disorder Treatments In Development




Treatments Awaiting Approval/Phase Trials



Awaiting Approval



Advate



Angiomax



Hemopure



Phase Iii Clinical Trials



Dynepo



Flocor



Eculizumab



Exanta



Idraparinux



Polyheme



Procrit



Refacto Af



Rituxan



Phase Ii Clinical Trials



#



Amd3100



Azd6140



Cera



Decitabine



Hemolink



Hemoxin



Ica-17043



Marstem



R744



Razaxaban



Rnapc2



Phase I Clinical Trials



#



40sd02



Azd9684



Bay 59-7939



Coagulin-B



Dx-88



Factor Viii Gene Therapy



Gh9001



Iron Chelator



Toleragen



Pld-117



Pt-100



R1516



Sr 123781



Atryn


Industry Structure

Competitive Analysis



Table 25 Total Worldwide Manufacturers' Market Shares Of Blood Disorder Treatments By Revenues At Manufacturers' Sales Levels, 2003



Figure 15 Total Worldwide Manufacturers' Market Shares Of Blood Disorder Treatments, By Revenues, At Manufacturers' Sales Levels, 2003



Industry Participants By Product Type



Table 26 Blood Disorder Treatment Manufacturers By Product Type, 2003


Patents

Patent Analysis By Manufacturer



Table 27 Selected Manufacturer Patents For Blood Disorder And Related Technology By Application, 1976-Present



Patents By Application



Anemia Applications



Hemophilia



Neutropenia



Thrombosis



Leading Market Manufacturers



Table 28 Patent Analysis By Selected Leading Blood Disorder Treatment Manufacturers, 1976-Present


Company Profiles

Abbott Laboratories



History



Amgen, Inc.



History



Astrazeneca, Plc



History



Aventis Behring



History



Baxter Intl., Inc.



History



Bayer Ag



History



Biopure Corp.



History



Bristol-Myers Squibb Co.



History



Boehringer Ingelheim, Gmbh



History



Chugai Pharmaceutical Co., Ltd.



History



Eli Lilly & Company



History



Genentech, Inc.



History



Glaxosmithkline, Plc



History



Millennium Pharmaceuticals, Inc.



History



Novo Nordisk A/S



History



Ortho Biotech Products, Lp



History



Otsuka America, Inc.



History



Pfizer, Inc.



History



Roche



History



Sankyo Co., Ltd.



History



Sanofi-Synthelabo



History



Schering-Plough Corp.



History



Shire Pharmaceuticals Group, Plc



History



Wyeth



History


Appendices

Company Contact Information



Table 29 Extended Company List



Blood Disorder Associations And Resources Contact Information




Abstract

This timely BCC report details the market for blood disorder treatments. Several key issues are discussed in detail including the great need to educate patients and others about blood clots. The impact of thrombosis is underestimated. More than five million individuals are affected each year and it is the third most common cardiovascular event worldwide. Deep vein thrombosis (DVT) and pulmonary embolism (PE) account for more than 250,000 hospitalizations in the United States each year. DVT and PE can be silent killers, because patients do not always present with typical signs and symptoms. That makes the detection of DVT and PE much more difficult. Education seems to be the key to addressing this need. The report contains: Identification of the different products used to treat various blood disorders; Details on the blood disorder market size and its participants; Discussion of products in research and development; Details of the industry, its relationship to the health-care industry, its economic consequences and its participants; Market forecasts through 2008 for the following product segments: anemia, hemophilia, neutropenia and thrombosis.

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